Motif ID: SMAD1

Z-value: 3.448


Transcription factors associated with SMAD1:

Gene SymbolEntrez IDGene Name
SMAD1 ENSG00000170365.5 SMAD1



Activity profile for motif SMAD1.

activity profile for motif SMAD1


Sorted Z-values histogram for motif SMAD1

Sorted Z-values for motif SMAD1



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_102608306 13.214 ENST00000332549.3
IL1R2
interleukin 1 receptor, type II
chr6_-_33048483 8.003 ENST00000419277.1
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chr14_-_106209368 7.182 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
IGHG1


immunoglobulin heavy constant gamma 1 (G1m marker)


chr22_+_23077065 5.889 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr18_-_11148587 5.375 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2


piezo-type mechanosensitive ion channel component 2


chr11_+_121461097 5.170 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr22_+_23040274 4.910 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr22_+_23247030 4.909 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr14_-_106111127 4.782 ENST00000390545.2
IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_106092403 4.559 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr22_+_23241661 4.527 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr14_-_106237742 4.485 ENST00000390551.2
IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr21_-_46330545 4.445 ENST00000320216.6
ENST00000397852.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr22_+_23134974 4.323 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr15_+_89181974 4.210 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_33043703 4.137 ENST00000418931.2
ENST00000535465.1
HLA-DPB1

major histocompatibility complex, class II, DP beta 1

chr22_+_23264766 4.049 ENST00000390331.2
IGLC7
immunoglobulin lambda constant 7
chr19_+_4229495 3.960 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr2_+_102624977 3.662 ENST00000441002.1
IL1R2
interleukin 1 receptor, type II
chr6_+_33048222 3.631 ENST00000428835.1
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr6_-_31239846 3.579 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C


major histocompatibility complex, class I, C


chr6_+_29910301 3.422 ENST00000376809.5
ENST00000376802.2
HLA-A

major histocompatibility complex, class I, A

chr15_+_89182178 3.417 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr15_+_89182156 3.350 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr3_+_53195136 3.261 ENST00000394729.2
ENST00000330452.3
PRKCD

protein kinase C, delta

chr6_+_32709119 3.248 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr14_-_106692191 3.177 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr6_-_29527702 3.172 ENST00000377050.4
UBD
ubiquitin D
chr19_+_49838653 3.110 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37





CD37 molecule





chr19_-_7764281 3.089 ENST00000360067.4
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr16_+_3115378 2.924 ENST00000529550.1
ENST00000551122.1
ENST00000525643.2
ENST00000548807.1
ENST00000528163.2
IL32




interleukin 32




chr1_+_192544857 2.831 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chr2_-_158345462 2.816 ENST00000439355.1
ENST00000540637.1
CYTIP

cytohesin 1 interacting protein

chr19_+_6531010 2.791 ENST00000245817.3
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr22_+_23243156 2.734 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr22_+_23237555 2.724 ENST00000390321.2
IGLC1
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_32605195 2.711 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr22_+_23165153 2.702 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chr6_+_31583761 2.688 ENST00000376049.4
AIF1
allograft inflammatory factor 1
chr22_+_23101182 2.551 ENST00000390312.2
IGLV2-14
immunoglobulin lambda variable 2-14
chr14_-_106406090 2.543 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr6_-_32784687 2.537 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr11_+_121447469 2.524 ENST00000532694.1
ENST00000534286.1
SORL1

sortilin-related receptor, L(DLR class) A repeats containing

chr16_+_3115323 2.484 ENST00000531965.1
ENST00000396887.3
ENST00000529699.1
ENST00000526464.2
ENST00000440815.3
IL32




interleukin 32




chr4_+_128554081 2.482 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr19_+_42381337 2.465 ENST00000597454.1
ENST00000444740.2
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr7_+_73623717 2.448 ENST00000344995.5
ENST00000460943.1
LAT2

linker for activation of T cells family, member 2

chr16_-_11681316 2.422 ENST00000571688.1
LITAF
lipopolysaccharide-induced TNF factor
chr16_+_32077386 2.374 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr15_+_81589254 2.332 ENST00000394652.2
IL16
interleukin 16
chr16_+_3115298 2.330 ENST00000325568.5
ENST00000534507.1
IL32

interleukin 32

chr14_-_106054659 2.325 ENST00000390539.2
IGHA2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr12_+_7055631 2.302 ENST00000543115.1
ENST00000399448.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr6_+_29691198 2.297 ENST00000440587.2
ENST00000434407.2
HLA-F

major histocompatibility complex, class I, F

chr19_-_7766991 2.292 ENST00000597921.1
ENST00000346664.5
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr14_-_106471723 2.281 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr15_-_79237433 2.263 ENST00000220166.5
CTSH
cathepsin H
chr17_-_29641104 2.241 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr6_-_31324943 2.227 ENST00000412585.2
ENST00000434333.1
HLA-B

major histocompatibility complex, class I, B

chr6_-_31550192 2.222 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr18_-_74844713 2.201 ENST00000397860.3
MBP
myelin basic protein
chr17_+_34640031 2.201 ENST00000339270.6
ENST00000482104.1
CCL4L2

chemokine (C-C motif) ligand 4-like 2

chr19_+_42381173 2.194 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr15_+_75074410 2.160 ENST00000439220.2
CSK
c-src tyrosine kinase
chr22_+_21133469 2.159 ENST00000406799.1
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr19_+_18284477 2.154 ENST00000407280.3
IFI30
interferon, gamma-inducible protein 30
chr2_+_68592305 2.153 ENST00000234313.7
PLEK
pleckstrin
chr14_+_105953204 2.121 ENST00000409393.2
CRIP1
cysteine-rich protein 1 (intestinal)
chr22_-_37545972 2.112 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr20_+_49411523 2.104 ENST00000371608.2
BCAS4
breast carcinoma amplified sequence 4
chr1_+_32739733 2.101 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr14_+_105953246 2.080 ENST00000392531.3
CRIP1
cysteine-rich protein 1 (intestinal)
chr9_+_137298396 2.066 ENST00000540193.1
RXRA
retinoid X receptor, alpha
chr1_+_12185949 2.052 ENST00000413146.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr6_+_32605134 2.017 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1


major histocompatibility complex, class II, DQ alpha 1


chr12_-_8765446 2.004 ENST00000537228.1
ENST00000229335.6
AICDA

activation-induced cytidine deaminase

chr22_+_23229960 1.991 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5


immunoglobulin lambda-like polypeptide 5


chr4_-_40517984 1.978 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr6_+_6588316 1.973 ENST00000379953.2
LY86
lymphocyte antigen 86
chr17_+_34431212 1.972 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr19_+_50922187 1.966 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB





Spi-B transcription factor (Spi-1/PU.1 related)





chr17_+_34639793 1.960 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2


chemokine (C-C motif) ligand 4-like 2


chr16_+_3115611 1.950 ENST00000530890.1
ENST00000444393.3
ENST00000533097.2
ENST00000008180.9
ENST00000396890.2
ENST00000525228.1
ENST00000548652.1
ENST00000525377.2
ENST00000530538.2
ENST00000549213.1
ENST00000552936.1
ENST00000548476.1
ENST00000552664.1
ENST00000552356.1
ENST00000551513.1
ENST00000382213.3
ENST00000548246.1
IL32
















interleukin 32
















chr1_+_207627575 1.943 ENST00000367058.3
ENST00000367057.3
ENST00000367059.3
CR2


complement component (3d/Epstein Barr virus) receptor 2


chr19_-_2041159 1.942 ENST00000589441.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr14_-_106174960 1.925 ENST00000390547.2
IGHA1
immunoglobulin heavy constant alpha 1
chr12_+_113344582 1.923 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1


2'-5'-oligoadenylate synthetase 1, 40/46kDa


chr17_-_46507567 1.906 ENST00000584924.1
SKAP1
src kinase associated phosphoprotein 1
chr17_-_29641084 1.900 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr14_+_105952648 1.894 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr14_-_106322288 1.892 ENST00000390559.2
IGHM
immunoglobulin heavy constant mu
chr15_+_45926919 1.882 ENST00000561735.1
ENST00000260324.7
SQRDL

sulfide quinone reductase-like (yeast)

chr14_-_106539557 1.881 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr11_-_116708302 1.866 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1



apolipoprotein A-I



chr17_+_41158742 1.862 ENST00000415816.2
ENST00000438323.2
IFI35

interferon-induced protein 35

chr14_-_107219365 1.859 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr19_-_39108568 1.838 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr3_+_52828805 1.830 ENST00000416872.2
ENST00000449956.2
ITIH3

inter-alpha-trypsin inhibitor heavy chain 3

chr14_+_21249200 1.818 ENST00000304677.2
RNASE6
ribonuclease, RNase A family, k6
chr14_-_106733624 1.816 ENST00000390610.2
IGHV1-24
immunoglobulin heavy variable 1-24
chr8_+_123793633 1.802 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr14_-_96180435 1.800 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
TCL1A



T-cell leukemia/lymphoma 1A



chr1_-_31230650 1.749 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr14_+_23016437 1.747 ENST00000478163.3
TRAC
T cell receptor alpha constant
chr12_+_7060432 1.746 ENST00000318974.9
ENST00000456013.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr16_-_55866997 1.745 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr15_-_20193370 1.742 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_+_46740730 1.738 ENST00000311907.5
ENST00000530231.1
ENST00000442468.1
F2


coagulation factor II (thrombin)


chr19_-_23578220 1.736 ENST00000595533.1
ENST00000397082.2
ENST00000599743.1
ENST00000300619.7
ZNF91



zinc finger protein 91



chr6_+_106959718 1.734 ENST00000369066.3
AIM1
absent in melanoma 1
chr2_+_33701286 1.728 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_+_30483962 1.726 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr13_-_99959641 1.690 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr12_+_7055767 1.689 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_+_65613340 1.660 ENST00000546702.1
AK4
adenylate kinase 4
chr1_+_79086088 1.653 ENST00000370751.5
ENST00000342282.3
IFI44L

interferon-induced protein 44-like

chr1_-_207095324 1.647 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr16_+_33605231 1.634 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr1_-_27961720 1.633 ENST00000545953.1
ENST00000374005.3
FGR

feline Gardner-Rasheed sarcoma viral oncogene homolog

chr19_-_2051223 1.625 ENST00000309340.7
ENST00000589534.1
ENST00000250896.3
ENST00000589509.1
MKNK2



MAP kinase interacting serine/threonine kinase 2



chr1_+_28206150 1.618 ENST00000456990.1
THEMIS2
thymocyte selection associated family member 2
chr1_-_111746966 1.609 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr6_+_29691056 1.608 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F


major histocompatibility complex, class I, F


chr22_+_18593446 1.603 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr16_+_28943260 1.576 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19


CD19 molecule


chr7_+_73624327 1.575 ENST00000361082.3
ENST00000275635.7
ENST00000470709.1
LAT2


linker for activation of T cells family, member 2


chr8_-_101348408 1.573 ENST00000519527.1
ENST00000522369.1
RNF19A

ring finger protein 19A, RBR E3 ubiquitin protein ligase

chr22_+_25003626 1.572 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1


gamma-glutamyltransferase 1


chr20_+_37434329 1.565 ENST00000299824.1
ENST00000373331.2
PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr9_-_116840728 1.553 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr15_+_81591757 1.540 ENST00000558332.1
IL16
interleukin 16
chr12_-_719573 1.537 ENST00000397265.3
NINJ2
ninjurin 2
chr1_+_6105974 1.528 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_-_24797546 1.524 ENST00000414428.1
ENST00000419307.1
ENST00000342947.3
DFNA5


deafness, autosomal dominant 5


chr19_-_12777509 1.522 ENST00000221363.4
ENST00000598876.1
ENST00000456935.2
ENST00000486847.2
MAN2B1



mannosidase, alpha, class 2B, member 1



chr1_+_13516066 1.518 ENST00000332192.6
PRAMEF21
PRAME family member 21
chr21_-_43816052 1.510 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr19_+_55141948 1.491 ENST00000396332.4
ENST00000427581.2
LILRB1

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1

chr2_+_90077680 1.485 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr8_+_28174649 1.482 ENST00000301908.3
PNOC
prepronociceptin
chr1_-_160681593 1.473 ENST00000368045.3
ENST00000368046.3
CD48

CD48 molecule

chr9_-_37034028 1.471 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr16_+_8806800 1.457 ENST00000561870.1
ENST00000396600.2
ABAT

4-aminobutyrate aminotransferase

chr19_+_39897453 1.453 ENST00000597629.1
ENST00000248673.3
ENST00000594045.1
ENST00000594442.1
ZFP36



ZFP36 ring finger protein



chr19_-_6481776 1.447 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C


DENN/MADD domain containing 1C


chr14_-_106994333 1.444 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr17_+_34430980 1.415 ENST00000250151.4
CCL4
chemokine (C-C motif) ligand 4
chr6_+_29795595 1.409 ENST00000360323.6
ENST00000376818.3
ENST00000376815.3
HLA-G


major histocompatibility complex, class I, G


chr6_-_90121789 1.400 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr1_+_207627697 1.398 ENST00000458541.2
CR2
complement component (3d/Epstein Barr virus) receptor 2
chr22_-_20368028 1.396 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr1_+_156123318 1.393 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_65613217 1.389 ENST00000545314.1
AK4
adenylate kinase 4
chr1_-_9131776 1.372 ENST00000484798.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_+_95691417 1.371 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr14_+_24563262 1.367 ENST00000559250.1
ENST00000216780.4
ENST00000560736.1
ENST00000396973.4
ENST00000559837.1
PCK2




phosphoenolpyruvate carboxykinase 2 (mitochondrial)




chr11_-_67205538 1.365 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr12_+_113344755 1.365 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_114135004 1.363 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_65613513 1.361 ENST00000395334.2
AK4
adenylate kinase 4
chr14_-_106963409 1.361 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr12_+_113354341 1.354 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr1_+_160709055 1.353 ENST00000368043.3
ENST00000368042.3
ENST00000458602.2
ENST00000458104.2
SLAMF7



SLAM family member 7



chr1_+_32716840 1.352 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr19_-_51875523 1.350 ENST00000593572.1
ENST00000595157.1
NKG7

natural killer cell group 7 sequence

chr19_-_6690723 1.347 ENST00000601008.1
C3
complement component 3
chr15_+_75335604 1.340 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr1_+_32716857 1.337 ENST00000482949.1
ENST00000495610.2
LCK

lymphocyte-specific protein tyrosine kinase

chr20_+_49411431 1.335 ENST00000358791.5
ENST00000262591.5
BCAS4

breast carcinoma amplified sequence 4

chr17_-_26903900 1.333 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC



aldolase C, fructose-bisphosphate



chr8_+_28351707 1.330 ENST00000537916.1
ENST00000523546.1
ENST00000240093.3
FZD3


frizzled family receptor 3


chr17_-_7080227 1.330 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr22_-_37640456 1.327 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2


ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)


chr6_-_32812420 1.323 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr4_+_15779901 1.317 ENST00000226279.3
CD38
CD38 molecule
chr12_+_113416191 1.313 ENST00000342315.4
ENST00000392583.2
OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa

chr19_+_1067271 1.307 ENST00000536472.1
ENST00000590214.1
HMHA1

histocompatibility (minor) HA-1

chr10_+_114133773 1.301 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr7_-_37024665 1.299 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr3_-_49395705 1.292 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr6_+_13272904 1.285 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr18_-_10701979 1.281 ENST00000538948.1
ENST00000285141.4
PIEZO2

piezo-type mechanosensitive ion channel component 2

chr19_-_6591113 1.280 ENST00000423145.3
ENST00000245903.3
CD70

CD70 molecule

chr1_-_169680745 1.279 ENST00000236147.4
SELL
selectin L
chr9_+_71320596 1.269 ENST00000265382.3
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr12_+_27485785 1.265 ENST00000544915.1
ARNTL2
aryl hydrocarbon receptor nuclear translocator-like 2
chr22_+_22930626 1.245 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr3_+_121554046 1.239 ENST00000273668.2
ENST00000451944.2
EAF2

ELL associated factor 2

chr7_+_101928380 1.238 ENST00000536178.1
SH2B2
SH2B adaptor protein 2
chr1_-_207095212 1.235 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr14_+_24563510 1.234 ENST00000545054.2
ENST00000561286.1
ENST00000558096.1
PCK2


phosphoenolpyruvate carboxykinase 2 (mitochondrial)


chrX_-_131547596 1.226 ENST00000538204.1
ENST00000370849.3
MBNL3

muscleblind-like splicing regulator 3

chr17_-_62009621 1.223 ENST00000349817.2
ENST00000392795.3
CD79B

CD79b molecule, immunoglobulin-associated beta

chr11_+_5617952 1.217 ENST00000354852.5
TRIM6-TRIM34
TRIM6-TRIM34 readthrough
chr1_+_111770232 1.206 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr2_+_241564655 1.204 ENST00000407714.1
GPR35
G protein-coupled receptor 35
chr17_+_67498538 1.196 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr13_-_47012325 1.195 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr6_-_154677900 1.188 ENST00000265198.4
ENST00000520261.1
IPCEF1

interaction protein for cytohesin exchange factors 1

chr6_+_14117872 1.188 ENST00000379153.3
CD83
CD83 molecule

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.3 5.2 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
1.2 29.4 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
1.1 3.3 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.9 6.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9 0.9 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.8 3.3 GO:0070842 aggresome assembly(GO:0070842)
0.8 2.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.7 2.8 GO:0033622 integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625)
0.7 17.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.7 2.6 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.6 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.6 2.4 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.6 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.6 1.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.6 0.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.5 17.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.5 2.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.5 3.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 3.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 2.7 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.5 2.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 0.5 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 1.5 GO:0035419 activation of MAPK activity involved in innate immune response(GO:0035419)
0.5 2.9 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.5 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.5 1.4 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.5 1.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 2.8 GO:0002335 mature B cell differentiation(GO:0002335)
0.4 1.3 GO:0021754 facial nucleus development(GO:0021754)
0.4 0.9 GO:0021571 rhombomere 5 development(GO:0021571)
0.4 0.9 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.4 1.7 GO:0030101 natural killer cell activation(GO:0030101)
0.4 3.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 1.7 GO:0006408 snRNA export from nucleus(GO:0006408) snRNA transport(GO:0051030)
0.4 0.8 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.4 1.5 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.4 1.5 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.4 9.0 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.4 3.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.4 2.5 GO:0015755 fructose transport(GO:0015755)
0.4 0.4 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.4 2.1 GO:0006562 proline catabolic process(GO:0006562)
0.3 1.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.3 1.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.3 2.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.3 2.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 2.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.3 0.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 2.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.3 1.7 GO:0060263 regulation of respiratory burst(GO:0060263)
0.3 1.3 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.3 3.0 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.3 1.0 GO:0048143 astrocyte activation(GO:0048143)
0.3 1.6 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.3 1.9 GO:0009649 entrainment of circadian clock(GO:0009649)
0.3 0.9 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.3 0.9 GO:0061024 membrane organization(GO:0061024)
0.3 1.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.3 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.3 2.2 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.3 0.9 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.3 4.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 0.9 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
0.3 1.8 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.3 0.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 0.8 GO:0042097 lymphotoxin A production(GO:0032641) interleukin-4 biosynthetic process(GO:0042097) lymphotoxin A biosynthetic process(GO:0042109) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.3 0.5 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 3.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 1.3 GO:0045576 mast cell activation(GO:0045576)
0.3 0.8 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.3 0.8 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.3 2.3 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 1.7 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.2 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 0.7 GO:0009635 response to herbicide(GO:0009635)
0.2 2.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 2.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.2 0.9 GO:0033986 response to methanol(GO:0033986) response to chromate(GO:0046687)
0.2 1.1 GO:0072125 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.2 1.3 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.2 2.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.2 0.2 GO:0006007 glucose catabolic process(GO:0006007)
0.2 6.3 GO:0097530 granulocyte chemotaxis(GO:0071621) granulocyte migration(GO:0097530)
0.2 1.7 GO:0006013 mannose metabolic process(GO:0006013)
0.2 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.4 GO:0046732 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by virus of host immune response(GO:0075528)
0.2 1.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.2 GO:0050772 positive regulation of axon extension(GO:0045773) positive regulation of axonogenesis(GO:0050772)
0.2 0.8 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.2 0.6 GO:0021836 chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.2 3.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.2 GO:0099515 nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.2 0.8 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 1.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 0.6 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.2 0.8 GO:0046827 regulation of protein export from nucleus(GO:0046825) positive regulation of protein export from nucleus(GO:0046827)
0.2 1.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.2 1.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.4 GO:0034695 response to prostaglandin E(GO:0034695)
0.2 0.4 GO:0014040 regulation of Schwann cell differentiation(GO:0014038) positive regulation of Schwann cell differentiation(GO:0014040)
0.2 0.6 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.2 1.7 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 1.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.2 0.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 1.5 GO:0001782 B cell homeostasis(GO:0001782)
0.2 2.3 GO:0002920 regulation of humoral immune response(GO:0002920)
0.2 2.5 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.2 0.8 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 0.6 GO:0071848 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) TNFSF11-mediated signaling pathway(GO:0071847) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.2 3.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 0.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 1.7 GO:0042940 D-amino acid transport(GO:0042940)
0.2 0.6 GO:0034126 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) positive regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034126)
0.2 1.5 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 0.5 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.2 2.7 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.4 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.2 0.2 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.2 1.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.2 0.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.2 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.2 1.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 0.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 1.7 GO:0015074 DNA integration(GO:0015074)
0.2 0.5 GO:0032570 response to progesterone(GO:0032570)
0.2 0.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.8 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.2 0.3 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.2 0.8 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.2 0.6 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.2 4.9 GO:0006968 cellular defense response(GO:0006968)
0.2 0.6 GO:0045299 otolith mineralization(GO:0045299)
0.2 0.5 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.2 1.2 GO:0015886 heme transport(GO:0015886)
0.2 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.6 GO:0048302 isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302)
0.1 6.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 1.2 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1 1.3 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.7 GO:0045010 actin nucleation(GO:0045010)
0.1 0.4 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.4 GO:0045475 locomotor rhythm(GO:0045475)
0.1 2.8 GO:0031648 protein destabilization(GO:0031648)
0.1 0.4 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 2.4 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 9.7 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.4 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting two-sector ATPase complex assembly(GO:0070071) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.9 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.5 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.1 1.8 GO:0045730 respiratory burst(GO:0045730)
0.1 2.2 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.1 1.8 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.1 GO:0045066 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) regulatory T cell differentiation(GO:0045066)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.3 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.1 1.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.6 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.5 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.2 GO:0090042 tubulin deacetylation(GO:0090042)
0.1 1.4 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.1 1.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 2.0 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.1 2.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.3 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.1 0.3 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 0.5 GO:0070482 response to oxygen levels(GO:0070482)
0.1 0.5 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.8 GO:0045007 depurination(GO:0045007)
0.1 0.3 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.8 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.7 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.1 0.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 1.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.3 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.1 0.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 7.1 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 0.3 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1 0.7 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 1.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 2.1 GO:0006298 mismatch repair(GO:0006298)
0.1 0.3 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.5 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0052510 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.1 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.2 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1 2.0 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.5 GO:0006857 oligopeptide transport(GO:0006857)
0.1 2.0 GO:0006825 copper ion transport(GO:0006825)
0.1 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.9 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 0.8 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.6 GO:0046618 drug export(GO:0046618)
0.1 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.8 GO:0030225 macrophage differentiation(GO:0030225)
0.1 0.3 GO:0010629 negative regulation of gene expression(GO:0010629)
0.1 0.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.5 GO:0071398 cellular response to fatty acid(GO:0071398)
0.1 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.8 GO:0006301 postreplication repair(GO:0006301)
0.1 0.6 GO:0016075 rRNA catabolic process(GO:0016075)
0.1 0.3 GO:0030307 positive regulation of cell growth(GO:0030307)
0.1 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 3.0 GO:0019079 viral genome replication(GO:0019079)
0.1 0.3 GO:1901722 regulation of cell proliferation involved in kidney development(GO:1901722)
0.1 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 0.2 GO:0007492 endoderm development(GO:0007492)
0.1 0.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 1.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.1 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1 0.2 GO:1904396 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.1 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.2 GO:0014063 regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.1 0.4 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.4 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.1 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.1 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleotide catabolic process(GO:0009155) deoxyribonucleoside triphosphate catabolic process(GO:0009204) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217)
0.1 0.5 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.2 GO:0010430 ethanol catabolic process(GO:0006068) fatty acid omega-oxidation(GO:0010430)
0.1 0.1 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.1 57.0 GO:0006955 immune response(GO:0006955)
0.1 0.2 GO:0046210 nitric oxide catabolic process(GO:0046210)
0.1 0.4 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.1 GO:0033002 muscle cell proliferation(GO:0033002)
0.1 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.6 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.3 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0006848 pyruvate transport(GO:0006848)
0.1 0.7 GO:0009404 toxin metabolic process(GO:0009404)
0.1 2.1 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.1 1.1 GO:0001662 behavioral fear response(GO:0001662)
0.1 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.3 GO:0043687 post-translational protein modification(GO:0043687)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 3.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 0.1 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.1 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.1 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0021794 thalamus development(GO:0021794)
0.1 1.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.9 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 1.5 GO:0019827 stem cell population maintenance(GO:0019827)
0.1 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.2 GO:0032096 negative regulation of response to food(GO:0032096)
0.1 0.5 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.1 0.2 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.1 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.4 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 0.2 GO:0010155 regulation of proton transport(GO:0010155)
0.1 0.2 GO:0032094 response to food(GO:0032094)
0.1 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.2 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1 0.2 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.1 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.1 GO:0009056 catabolic process(GO:0009056)
0.1 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.1 0.2 GO:0007285 primary spermatocyte growth(GO:0007285)
0.1 1.6 GO:0031424 keratinization(GO:0031424)
0.1 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.2 GO:0048341 renal glucose absorption(GO:0035623) paraxial mesoderm formation(GO:0048341)
0.1 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.3 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.2 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.5 GO:0006734 NADH metabolic process(GO:0006734)
0.1 0.6 GO:0006907 pinocytosis(GO:0006907)
0.1 0.5 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 0.2 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.4 GO:0009304 tRNA transcription(GO:0009304)
0.1 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.3 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.3 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278)
0.0 0.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.3 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.4 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.4 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.2 GO:0060070 canonical Wnt signaling pathway(GO:0060070)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.3 GO:0050812 acetyl-CoA biosynthetic process(GO:0006085) acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.2 GO:0098727 maintenance of cell number(GO:0098727)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.1 GO:0045778 positive regulation of ossification(GO:0045778)
0.0 0.2 GO:0006266 DNA ligation(GO:0006266)
0.0 0.2 GO:0048469 cell maturation(GO:0048469)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 1.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.0 GO:0014028 notochord formation(GO:0014028)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.2 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.6 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.4 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.4 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.3 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.9 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.1 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.5 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.1 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.0 0.1 GO:0033344 cholesterol efflux(GO:0033344)
0.0 4.0 GO:0016125 sterol metabolic process(GO:0016125)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.9 GO:0009451 RNA modification(GO:0009451)
0.0 0.4 GO:0070206 protein trimerization(GO:0070206)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0030147 obsolete natriuresis(GO:0030147)
0.0 0.2 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0090102 cochlea development(GO:0090102)
0.0 0.8 GO:0010243 response to organonitrogen compound(GO:0010243)
0.0 0.1 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.2 GO:0007143 female meiotic division(GO:0007143)
0.0 0.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.5 GO:0001906 cell killing(GO:0001906)
0.0 0.1 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0050766 regulation of phagocytosis(GO:0050764) positive regulation of phagocytosis(GO:0050766)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0060209 estrus(GO:0060209)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0032365 intracellular lipid transport(GO:0032365)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.1 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.4 GO:1903902 positive regulation of viral process(GO:0048524) positive regulation of viral transcription(GO:0050434) positive regulation of viral life cycle(GO:1903902)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 8.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0015992 proton transport(GO:0015992)
0.0 0.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173) ERBB signaling pathway(GO:0038127)
0.0 0.2 GO:0009268 response to pH(GO:0009268)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.0 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.2 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.0 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0003289 atrial septum development(GO:0003283) septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) atrial septum morphogenesis(GO:0060413)
0.0 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0061448 connective tissue development(GO:0061448)
0.0 0.9 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0045333 cellular respiration(GO:0045333)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 3.6 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.6 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.3 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 1.2 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0008272 sulfate transport(GO:0008272)
0.0 0.0 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.0 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.1 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.0 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.2 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.1 GO:2000737 negative regulation of stem cell differentiation(GO:2000737)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 1.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0035050 embryonic heart tube development(GO:0035050)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.1 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:0042551 neuron maturation(GO:0042551)
0.0 0.1 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.0 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0050954 sensory perception of mechanical stimulus(GO:0050954)
0.0 0.1 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0009791 post-embryonic development(GO:0009791)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 29.7 GO:0042613 MHC class II protein complex(GO:0042613)
1.1 6.6 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.6 2.5 GO:0033269 internode region of axon(GO:0033269)
0.6 2.4 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.5 13.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 0.5 GO:0031526 brush border membrane(GO:0031526)
0.5 1.4 GO:0000802 transverse filament(GO:0000802)
0.4 2.9 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.3 7.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.3 4.7 GO:0000242 pericentriolar material(GO:0000242)
0.3 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.0 GO:0001891 phagocytic cup(GO:0001891)
0.3 3.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 1.6 GO:0045179 apical cortex(GO:0045179)
0.3 0.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.2 11.4 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.2 0.7 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 3.9 GO:0016235 aggresome(GO:0016235)
0.2 2.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.1 GO:0032449 CBM complex(GO:0032449)
0.2 0.2 GO:0009295 nucleoid(GO:0009295)
0.2 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.2 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 2.1 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.2 1.1 GO:0030870 Mre11 complex(GO:0030870)
0.2 2.9 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.5 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 4.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.1 GO:0031143 pseudopodium(GO:0031143)
0.1 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0070695 FHF complex(GO:0070695)
0.1 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.3 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 9.4 GO:0016605 PML body(GO:0016605)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.7 GO:0045120 pronucleus(GO:0045120)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.5 GO:0045202 synapse(GO:0045202)
0.1 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0019718 obsolete rough microsome(GO:0019718)
0.1 1.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.1 GO:0005903 brush border(GO:0005903)
0.1 1.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.4 GO:0045298 tubulin complex(GO:0045298)
0.1 4.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.4 GO:0070820 tertiary granule(GO:0070820)
0.1 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.4 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.7 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 10.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.5 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.4 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.1 0.6 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 3.1 GO:0005884 actin filament(GO:0005884)
0.1 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.2 GO:0001772 immunological synapse(GO:0001772)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.2 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 0.7 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.8 GO:0097223 sperm part(GO:0097223)
0.1 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.5 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 1.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 4.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.2 GO:0031224 intrinsic component of membrane(GO:0031224)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.3 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0071817 MMXD complex(GO:0071817)
0.0 5.9 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 12.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.5 GO:1990904 intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 8.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0000805 X chromosome(GO:0000805) Barr body(GO:0001740)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 1.1 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 1.1 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 13.2 GO:0005624 obsolete membrane fraction(GO:0005624)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.8 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.8 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 4.1 GO:0005792 obsolete microsome(GO:0005792)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0000803 sex chromosome(GO:0000803)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.0 GO:0070938 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000445 transcription export complex(GO:0000346) THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.0 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 18.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
3.7 11.0 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
1.6 4.8 GO:0042610 CD8 receptor binding(GO:0042610)
1.5 20.4 GO:0032395 MHC class II receptor activity(GO:0032395)
1.3 4.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
1.1 15.8 GO:0032393 MHC class I receptor activity(GO:0032393)
0.9 5.6 GO:0019863 IgE binding(GO:0019863)
0.9 2.6 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.7 41.9 GO:0003823 antigen binding(GO:0003823)
0.7 2.1 GO:0019976 interleukin-2 binding(GO:0019976)
0.6 2.4 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.6 2.3 GO:0008907 integrase activity(GO:0008907)
0.5 2.7 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.5 1.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.5 7.6 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.5 3.2 GO:0004875 complement receptor activity(GO:0004875)
0.5 2.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.5 2.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.5 2.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.5 2.1 GO:0019862 IgA binding(GO:0019862)
0.5 4.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 1.5 GO:0017129 triglyceride binding(GO:0017129)
0.5 1.8 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 2.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.4 1.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.4 1.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.4 1.7 GO:0016531 copper chaperone activity(GO:0016531)
0.4 3.7 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.4 2.9 GO:0001515 opioid peptide activity(GO:0001515)
0.4 1.2 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4 2.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.4 1.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.4 1.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.4 2.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 1.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 1.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.3 1.0 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.3 1.7 GO:0034711 inhibin binding(GO:0034711)
0.3 1.0 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.3 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.3 0.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.3 9.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 0.9 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.3 0.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 2.4 GO:0016778 diphosphotransferase activity(GO:0016778)
0.3 2.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.3 2.8 GO:0051400 BH domain binding(GO:0051400)
0.3 1.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.3 6.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 5.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.3 1.6 GO:0019238 cyclohydrolase activity(GO:0019238)
0.3 5.9 GO:0004697 protein kinase C activity(GO:0004697)
0.3 3.7 GO:0008199 ferric iron binding(GO:0008199)
0.3 1.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 1.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 3.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.7 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 0.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 3.1 GO:0070628 proteasome binding(GO:0070628)
0.2 0.7 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.2 1.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 0.6 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 2.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.2 1.0 GO:0017096 acetylserotonin O-methyltransferase activity(GO:0017096)
0.2 0.8 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.2 2.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 1.0 GO:0042379 chemokine receptor binding(GO:0042379)
0.2 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 0.6 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.2 0.5 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.2 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 0.9 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.7 GO:0005534 galactose binding(GO:0005534)
0.2 1.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 3.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 2.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 0.6 GO:0017040 ceramidase activity(GO:0017040)
0.2 1.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.6 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.6 GO:0034701 tripeptidase activity(GO:0034701)
0.2 0.8 GO:0070061 fructose binding(GO:0070061)
0.2 0.8 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 1.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 2.2 GO:0015926 glucosidase activity(GO:0015926)
0.1 0.4 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 1.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.4 GO:0004796 thromboxane-A synthase activity(GO:0004796)
0.1 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.4 GO:0015217 purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.1 0.4 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.4 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.8 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 7.8 GO:0001948 glycoprotein binding(GO:0001948)
0.1 0.9 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 2.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.9 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 2.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.8 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 0.4 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.6 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.5 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 1.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 0.7 GO:0060229 lipase activator activity(GO:0060229)
0.1 1.0 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 0.8 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 1.1 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0042562 hormone binding(GO:0042562)
0.1 0.5 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.6 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.5 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.1 4.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.4 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.6 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.8 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.5 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 1.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 2.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.2 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.4 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.9 GO:0043621 protein self-association(GO:0043621)
0.1 0.3 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.2 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 2.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 0.2 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.1 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0035276 ethanol binding(GO:0035276)
0.1 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.3 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
0.1 0.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.6 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.1 0.3 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 2.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0005497 androgen binding(GO:0005497)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.1 0.3 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.1 1.7 GO:0015026 coreceptor activity(GO:0015026)
0.1 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0019001 guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 2.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.2 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.1 0.2 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 1.0 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.6 GO:0002020 protease binding(GO:0002020)
0.1 0.8 GO:0008143 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.2 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.2 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 1.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.9 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0051184 cofactor transporter activity(GO:0051184)
0.0 0.0 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176) extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0046975 RNA polymerase II core binding(GO:0000993) histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.5 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 7.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.9 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.4 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 6.7 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 4.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0008753 NADPH dehydrogenase (quinone) activity(GO:0008753)
0.0 0.4 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.3 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0016803 epoxide hydrolase activity(GO:0004301) ether hydrolase activity(GO:0016803)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 3.5 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 8.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.0 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 1.2 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 1.0 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0046332 SMAD binding(GO:0046332)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.0 GO:0051765 obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity(GO:0035300) inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0016566 obsolete specific transcriptional repressor activity(GO:0016566)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004988 obsolete mu-opioid receptor activity(GO:0004988)
0.0 5.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.0 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0035258 steroid hormone receptor binding(GO:0035258)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.0 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.0 GO:0008159 obsolete negative transcription elongation factor activity(GO:0008148) obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 16.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.2 10.3 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.2 6.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.2 0.3 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 4.9 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 2.5 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 0.5 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.3 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.8 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 0.7 ST_GAQ_PATHWAY G alpha q Pathway
0.1 0.2 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.6 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes