Motif ID: SMAD2

Z-value: 0.989


Transcription factors associated with SMAD2:

Gene SymbolEntrez IDGene Name
SMAD2 ENSG00000175387.11 SMAD2



Activity profile for motif SMAD2.

activity profile for motif SMAD2


Sorted Z-values histogram for motif SMAD2

Sorted Z-values for motif SMAD2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_7297519 1.249 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chr17_-_15165854 1.234 ENST00000395936.1
ENST00000395938.2
PMP22

peripheral myelin protein 22

chr12_-_47473557 1.110 ENST00000321382.3
AMIGO2
adhesion molecule with Ig-like domain 2
chr11_-_33913708 1.069 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_-_47473642 1.052 ENST00000266581.4
AMIGO2
adhesion molecule with Ig-like domain 2
chr17_-_7297833 1.032 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr20_-_23066953 1.027 ENST00000246006.4
CD93
CD93 molecule
chr17_-_46623441 1.011 ENST00000330070.4
HOXB2
homeobox B2
chr12_-_47473425 1.009 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chrX_-_107018969 0.958 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr3_-_15374659 0.928 ENST00000426925.1
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr3_+_150321068 0.908 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
SELT


Selenoprotein T


chr20_+_43343517 0.873 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr6_+_6588316 0.850 ENST00000379953.2
LY86
lymphocyte antigen 86
chr20_+_43343886 0.839 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr20_+_43343476 0.835 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr17_+_68165657 0.756 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_+_93965451 0.743 ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chr1_-_153508460 0.701 ENST00000462776.2
S100A6
S100 calcium binding protein A6
chr6_+_6588902 0.640 ENST00000230568.4
LY86
lymphocyte antigen 86
chr17_+_7792101 0.638 ENST00000358181.4
ENST00000330494.7
CHD3

chromodomain helicase DNA binding protein 3

chr16_+_31483374 0.623 ENST00000394863.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr2_+_5832799 0.578 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr12_+_93965609 0.574 ENST00000549887.1
ENST00000551556.1
SOCS2

suppressor of cytokine signaling 2

chr8_-_95907423 0.571 ENST00000396133.3
ENST00000308108.4
CCNE2

cyclin E2

chr3_+_9834179 0.554 ENST00000498623.2
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr9_+_125137565 0.531 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_3571934 0.519 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chrX_-_107019181 0.518 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3



TSC22 domain family, member 3



chr1_+_100111479 0.517 ENST00000263174.4
PALMD
palmdelphin
chr3_+_52529346 0.514 ENST00000321725.6
STAB1
stabilin 1
chr5_-_150521192 0.499 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr1_+_100111580 0.498 ENST00000605497.1
PALMD
palmdelphin
chr11_-_108464465 0.492 ENST00000525344.1
EXPH5
exophilin 5
chr3_-_88108192 0.481 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr22_+_24891210 0.478 ENST00000382760.2
UPB1
ureidopropionase, beta
chr3_-_88108212 0.477 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr12_+_68042517 0.468 ENST00000393555.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr6_-_152489484 0.467 ENST00000354674.4
ENST00000539504.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr10_-_14372870 0.462 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr6_+_99282570 0.461 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr6_+_39760129 0.448 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr4_-_41216492 0.437 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr4_-_5890145 0.429 ENST00000397890.2
CRMP1
collapsin response mediator protein 1
chr4_-_41216473 0.420 ENST00000513140.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr22_+_29876197 0.418 ENST00000310624.6
NEFH
neurofilament, heavy polypeptide
chr12_-_10251576 0.413 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr12_-_8765446 0.405 ENST00000537228.1
ENST00000229335.6
AICDA

activation-induced cytidine deaminase

chr16_-_17564738 0.401 ENST00000261381.6
XYLT1
xylosyltransferase I
chr13_+_114238997 0.400 ENST00000538138.1
ENST00000375370.5
TFDP1

transcription factor Dp-1

chr12_-_10251603 0.383 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr1_+_16693578 0.374 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SZRD1




SUZ RNA binding domain containing 1




chr9_+_101867359 0.369 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr1_-_211752073 0.361 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr8_+_82192501 0.346 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr6_+_39760783 0.343 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr21_-_38639813 0.342 ENST00000309117.6
ENST00000398998.1
DSCR3

Down syndrome critical region gene 3

chr3_-_49761337 0.341 ENST00000308388.6
ENST00000480687.1
ENST00000308375.6
ENST00000535833.1
GMPPB


AMIGO3
GDP-mannose pyrophosphorylase B


adhesion molecule with Ig-like domain 3
chr12_-_10251539 0.340 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr3_+_23847394 0.333 ENST00000306627.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr20_-_56284816 0.326 ENST00000395819.3
ENST00000341744.3
PMEPA1

prostate transmembrane protein, androgen induced 1

chr5_+_140762268 0.326 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr9_+_34990219 0.325 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr9_+_101867387 0.325 ENST00000374990.2
ENST00000552516.1
TGFBR1

transforming growth factor, beta receptor 1

chr6_+_143772060 0.312 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr3_+_130569592 0.312 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr7_-_10979750 0.312 ENST00000339600.5
NDUFA4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
chr11_-_107729887 0.309 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr4_-_41216619 0.302 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr4_-_103749205 0.296 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr11_+_75273101 0.293 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1


serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


chr3_+_130569429 0.289 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr11_-_107590383 0.280 ENST00000525934.1
ENST00000531293.1
SLN

sarcolipin

chr21_+_47401650 0.279 ENST00000361866.3
COL6A1
collagen, type VI, alpha 1
chr3_+_23847432 0.265 ENST00000346855.3
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr3_+_123813509 0.263 ENST00000460856.1
ENST00000240874.3
KALRN

kalirin, RhoGEF kinase

chr3_-_195163803 0.262 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr17_-_46178741 0.260 ENST00000581003.1
ENST00000225603.4
CBX1

chromobox homolog 1

chr1_-_149783914 0.235 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF


histone cluster 2, H2bf


chr12_+_53443963 0.234 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr1_-_149908217 0.225 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr4_-_164534657 0.224 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr12_-_56583243 0.221 ENST00000550164.1
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr11_+_117857063 0.219 ENST00000227752.3
ENST00000541785.1
ENST00000545409.1
IL10RA


interleukin 10 receptor, alpha


chr11_-_101454658 0.217 ENST00000344327.3
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr19_-_43383819 0.217 ENST00000312439.6
ENST00000403380.3
PSG1

pregnancy specific beta-1-glycoprotein 1

chr11_-_3859089 0.215 ENST00000396979.1
RHOG
ras homolog family member G
chr12_+_67663056 0.213 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr4_-_39979576 0.209 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr12_+_68042495 0.206 ENST00000344096.3
DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr12_-_71003568 0.206 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB




protein tyrosine phosphatase, receptor type, B




chr19_-_3606838 0.204 ENST00000375190.4
TBXA2R
thromboxane A2 receptor
chr2_+_113033164 0.204 ENST00000409871.1
ENST00000343936.4
ZC3H6

zinc finger CCCH-type containing 6

chr1_-_201915590 0.200 ENST00000367288.4
LMOD1
leiomodin 1 (smooth muscle)
chr12_-_120554534 0.191 ENST00000538903.1
ENST00000534951.1
RAB35

RAB35, member RAS oncogene family

chr11_+_71238313 0.190 ENST00000398536.4
KRTAP5-7
keratin associated protein 5-7
chr1_+_160085501 0.183 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr7_+_155250824 0.181 ENST00000297375.4
EN2
engrailed homeobox 2
chr12_-_104531785 0.176 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr19_-_44285401 0.169 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_+_28889801 0.165 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr7_-_102257139 0.165 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RASA4




RAS p21 protein activator 4




chr4_-_103749179 0.164 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr16_+_28889703 0.160 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr15_+_75498739 0.152 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr12_+_122516626 0.148 ENST00000319080.7
MLXIP
MLX interacting protein
chr1_-_44482979 0.148 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr9_+_15422702 0.147 ENST00000380821.3
ENST00000421710.1
SNAPC3

small nuclear RNA activating complex, polypeptide 3, 50kDa

chr1_-_207119738 0.144 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr1_+_160097462 0.143 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_149908710 0.143 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11


myotubularin related protein 11


chr22_-_24641027 0.141 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
GGT5




gamma-glutamyltransferase 5




chr22_+_22764088 0.135 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr20_+_1875942 0.132 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr22_+_31518938 0.131 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J






inositol polyphosphate-5-phosphatase J






chr5_+_140345820 0.130 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr6_+_30689401 0.130 ENST00000396389.1
ENST00000396384.1
TUBB

tubulin, beta class I

chr19_+_41594377 0.123 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chrX_+_153029633 0.120 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3



plexin B3



chr20_+_44098385 0.120 ENST00000217425.5
ENST00000339946.3
WFDC2

WAP four-disulfide core domain 2

chr12_-_3982511 0.116 ENST00000427057.2
ENST00000228820.4
PARP11

poly (ADP-ribose) polymerase family, member 11

chr19_-_11688447 0.115 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr4_-_103749313 0.112 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr22_-_31885514 0.110 ENST00000397525.1
EIF4ENIF1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr3_-_49131013 0.104 ENST00000424300.1
QRICH1
glutamine-rich 1
chr12_+_53443680 0.102 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr2_+_27237615 0.101 ENST00000458529.1
ENST00000402218.1
MAPRE3

microtubule-associated protein, RP/EB family, member 3

chr19_-_42636543 0.095 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2




POU class 2 homeobox 2




chr8_-_102217796 0.094 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706



zinc finger protein 706



chr19_+_49128209 0.089 ENST00000599748.1
ENST00000443164.1
ENST00000599029.1
SPHK2


sphingosine kinase 2


chr5_+_133861339 0.089 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr11_-_46142948 0.088 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr7_-_102158157 0.085 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B


RAS p21 protein activator 4B


chr1_-_44497118 0.085 ENST00000537678.1
ENST00000466926.1
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr19_-_14224969 0.083 ENST00000589994.1
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr20_+_44098346 0.083 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr9_+_133569108 0.081 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2





exosome component 2





chr17_-_1389419 0.076 ENST00000575158.1
MYO1C
myosin IC
chr11_+_2923423 0.076 ENST00000312221.5
SLC22A18
solute carrier family 22, member 18
chr14_+_62162258 0.075 ENST00000337138.4
ENST00000394997.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr14_+_70078303 0.071 ENST00000342745.4
KIAA0247
KIAA0247
chr15_+_68570062 0.069 ENST00000306917.4
FEM1B
fem-1 homolog b (C. elegans)
chr10_+_105314881 0.066 ENST00000437579.1
NEURL
neuralized E3 ubiquitin protein ligase 1
chr4_-_99851766 0.064 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr3_-_195603566 0.063 ENST00000424563.1
ENST00000411741.1
TNK2

tyrosine kinase, non-receptor, 2

chr7_-_105516923 0.060 ENST00000478915.1
ATXN7L1
ataxin 7-like 1
chr21_-_38338773 0.057 ENST00000399120.1
ENST00000419461.1
HLCS

holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)

chr9_-_136006496 0.056 ENST00000372062.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr12_-_57410304 0.053 ENST00000441881.1
ENST00000458521.2
TAC3

tachykinin 3

chr12_-_57472522 0.051 ENST00000379391.3
ENST00000300128.4
TMEM194A

transmembrane protein 194A

chr2_-_73053126 0.050 ENST00000272427.6
ENST00000410104.1
EXOC6B

exocyst complex component 6B

chr10_+_72972281 0.046 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr19_-_46105411 0.044 ENST00000544371.1
ENST00000323040.4
OPA3
GPR4
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
G protein-coupled receptor 4
chr2_+_168725458 0.043 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr19_+_13106383 0.042 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr7_+_107384579 0.041 ENST00000222597.2
ENST00000415884.2
CBLL1

Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase

chrX_-_47489244 0.041 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP


complement factor properdin


chr16_+_53164833 0.041 ENST00000564845.1
CHD9
chromodomain helicase DNA binding protein 9
chr19_-_42636617 0.037 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2




POU class 2 homeobox 2




chr16_-_67997947 0.037 ENST00000537830.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr12_-_89918522 0.036 ENST00000529983.2
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr1_+_156163880 0.036 ENST00000359511.4
ENST00000423538.2
SLC25A44

solute carrier family 25, member 44

chr11_-_34535297 0.036 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr2_-_72375167 0.034 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr22_+_22676808 0.033 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr19_-_54824344 0.030 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5



leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5



chr1_+_2407754 0.030 ENST00000419816.2
ENST00000378486.3
ENST00000378488.3
ENST00000288766.5
PLCH2



phospholipase C, eta 2



chr22_-_38851205 0.029 ENST00000303592.3
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr15_-_88799384 0.024 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr5_-_64064508 0.024 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr1_+_174933899 0.024 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_159141397 0.023 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3


cell adhesion molecule 3


chr8_+_94241867 0.023 ENST00000598428.1
AC016885.1
Uncharacterized protein
chr4_-_103748880 0.022 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr19_-_6481776 0.022 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C


DENN/MADD domain containing 1C


chr19_-_14606900 0.021 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1






GIPC PDZ domain containing family, member 1






chr3_-_150320937 0.016 ENST00000479209.1
SERP1
stress-associated endoplasmic reticulum protein 1
chr19_-_18337240 0.015 ENST00000262805.12
PDE4C
phosphodiesterase 4C, cAMP-specific
chr22_+_22735135 0.014 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr14_-_106478603 0.012 ENST00000390596.2
IGHV4-4
immunoglobulin heavy variable 4-4
chr4_-_103749105 0.011 ENST00000394801.4
ENST00000394804.2
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chrX_-_30595959 0.010 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr16_-_425205 0.009 ENST00000448854.1
TMEM8A
transmembrane protein 8A
chr15_-_88799661 0.009 ENST00000360948.2
ENST00000357724.2
ENST00000355254.2
ENST00000317501.3
NTRK3



neurotrophic tyrosine kinase, receptor, type 3



chr13_+_25670268 0.005 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr1_-_160040038 0.005 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr1_-_94586651 0.005 ENST00000535735.1
ENST00000370225.3
ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

chr19_+_11466167 0.002 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.2 0.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.7 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.4 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 1.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.5 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 3.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) mitochondrial calcium ion homeostasis(GO:0051560) positive regulation of mitochondrial calcium ion concentration(GO:0051561) relaxation of skeletal muscle(GO:0090076)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.6 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.1 1.2 GO:0032288 myelin assembly(GO:0032288)
0.1 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.4 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:0045010 actin nucleation(GO:0045010)
0.1 1.3 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 1.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.1 0.3 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 0.4 GO:0090281 negative regulation of neurotransmitter transport(GO:0051589) negative regulation of calcium ion import(GO:0090281)
0.1 0.3 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.0 GO:0042116 macrophage activation(GO:0042116)
0.0 0.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.7 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.5 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928) negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0070781 response to biotin(GO:0070781)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.7 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.5 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.3 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 1.7 GO:0006959 humoral immune response(GO:0006959)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.0 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0046618 drug transmembrane transport(GO:0006855) tetracycline transport(GO:0015904) drug export(GO:0046618)
0.0 0.4 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.0 GO:0008360 regulation of cell shape(GO:0008360)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0030904 retromer complex(GO:0030904)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0001940 male pronucleus(GO:0001940)
0.1 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.6 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.4 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 2.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.6 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187) glycine:sodium symporter activity(GO:0015375)
0.1 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.5 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.9 GO:0008430 selenium binding(GO:0008430)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.