ISMARA results: SOX1

Motif ID: SOX1

Z-value: 0.938

Transcription factors associated with SOX1:

Gene Symbol	Entrez ID	Gene Name
SOX1	ENSG00000182968.3	SOX1

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_12058961	4.200	ENST00000053243.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr16_+_12059050	4.074	ENST00000396495.3	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr16_+_12059091	2.601	ENST00000562385.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr3_-_189840223	1.932	ENST00000427335.2	LEPREL1	leprecan-like 1
chr3_-_16524357	1.411	ENST00000432519.1	RFTN1	raftlin, lipid raft linker 1
chr11_+_125496619	0.978	ENST00000532669.1 ENST00000278916.3	CHEK1	checkpoint kinase 1
chr3_-_58200398	0.970	ENST00000318316.3 ENST00000460422.1 ENST00000483681.1	DNASE1L3	deoxyribonuclease I-like 3
chr11_-_57177586	0.888	ENST00000529411.1	RP11-872D17.8	Uncharacterized protein
chr14_+_21249200	0.815	ENST00000304677.2	RNASE6	ribonuclease, RNase A family, k6
chr11_+_125496124	0.698	ENST00000533778.2 ENST00000534070.1	CHEK1	checkpoint kinase 1
chr2_+_102615416	0.657	ENST00000393414.2	IL1R2	interleukin 1 receptor, type II
chr11_+_125496400	0.650	ENST00000524737.1	CHEK1	checkpoint kinase 1
chr2_-_163175133	0.620	ENST00000421365.2 ENST00000263642.2	IFIH1	interferon induced with helicase C domain 1
chr1_+_152957707	0.614	ENST00000368762.1	SPRR1A	small proline-rich protein 1A
chr18_-_51751132	0.601	ENST00000256429.3	MBD2	methyl-CpG binding domain protein 2
chr20_-_14318248	0.567	ENST00000378053.3 ENST00000341420.4	FLRT3	fibronectin leucine rich transmembrane protein 3
chr3_+_178276488	0.561	ENST00000432997.1 ENST00000455865.1	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr12_-_110434096	0.553	ENST00000320063.9 ENST00000457474.2 ENST00000547815.1 ENST00000361006.5	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2
chr12_+_100594557	0.454	ENST00000546902.1 ENST00000552376.1 ENST00000551617.1	ACTR6	ARP6 actin-related protein 6 homolog (yeast)
chr16_-_11876408	0.429	ENST00000396516.2	ZC3H7A	zinc finger CCCH-type containing 7A
chr17_+_75181292	0.361	ENST00000431431.2	SEC14L1	SEC14-like 1 (S. cerevisiae)
chrX_+_129040122	0.330	ENST00000394422.3 ENST00000371051.5	UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr1_+_65613340	0.325	ENST00000546702.1	AK4	adenylate kinase 4
chr14_+_74417192	0.309	ENST00000554320.1	COQ6	coenzyme Q6 monooxygenase
chr10_-_73976025	0.289	ENST00000342444.4 ENST00000533958.1 ENST00000527593.1 ENST00000394915.3 ENST00000530461.1 ENST00000317168.6 ENST00000524829.1	ASCC1	activating signal cointegrator 1 complex subunit 1
chr19_-_10491234	0.289	ENST00000524462.1 ENST00000531836.1 ENST00000525621.1	TYK2	tyrosine kinase 2
chr1_+_65613217	0.288	ENST00000545314.1	AK4	adenylate kinase 4
chr1_-_212004090	0.283	ENST00000366997.4	LPGAT1	lysophosphatidylglycerol acyltransferase 1
chrX_+_129040094	0.275	ENST00000425117.2	UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr17_-_29624343	0.260	ENST00000247271.4	OMG	oligodendrocyte myelin glycoprotein
chr1_-_200379129	0.258	ENST00000367353.1	ZNF281	zinc finger protein 281
chr7_-_36634181	0.256	ENST00000538464.1	AOAH	acyloxyacyl hydrolase (neutrophil)
chrX_-_62974941	0.248	ENST00000374872.1 ENST00000253401.6 ENST00000374870.4	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_+_174769006	0.246	ENST00000489615.1	RABGAP1L	RAB GTPase activating protein 1-like
chr4_+_154622652	0.236	ENST00000260010.6	TLR2	toll-like receptor 2
chr19_+_49588677	0.214	ENST00000598984.1 ENST00000598441.1	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr1_-_43638168	0.208	ENST00000431635.2	EBNA1BP2	EBNA1 binding protein 2
chr3_-_44519131	0.198	ENST00000425708.2 ENST00000396077.2	ZNF445	zinc finger protein 445
chr3_-_58613323	0.197	ENST00000474531.1 ENST00000465970.1	FAM107A	family with sequence similarity 107, member A
chr13_-_22178284	0.189	ENST00000468222.2 ENST00000382374.4	MICU2	mitochondrial calcium uptake 2
chr3_-_126327398	0.181	ENST00000383572.2	TXNRD3NB	thioredoxin reductase 3 neighbor
chr2_+_11864458	0.172	ENST00000396098.1 ENST00000396099.1 ENST00000425416.2	LPIN1	lipin 1
chr3_-_185655795	0.167	ENST00000342294.4 ENST00000382191.4 ENST00000453386.2	TRA2B	transformer 2 beta homolog (Drosophila)
chr11_-_104827425	0.156	ENST00000393150.3	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr7_+_142457315	0.155	ENST00000486171.1 ENST00000311737.7	PRSS1	protease, serine, 1 (trypsin 1)
chr14_-_89878369	0.154	ENST00000553840.1 ENST00000556916.1	FOXN3	forkhead box N3
chr9_-_95244781	0.150	ENST00000375544.3 ENST00000375543.1 ENST00000395538.3 ENST00000450139.2	ASPN	asporin
chr19_+_49588690	0.145	ENST00000221448.5	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr6_-_46048116	0.142	ENST00000185206.6	CLIC5	chloride intracellular channel 5
chr5_-_150460914	0.136	ENST00000389378.2	TNIP1	TNFAIP3 interacting protein 1
chr22_-_30662828	0.134	ENST00000403463.1 ENST00000215781.2	OSM	oncostatin M
chr1_+_19578033	0.131	ENST00000330263.4	MRTO4	mRNA turnover 4 homolog (S. cerevisiae)
chr6_+_26183958	0.125	ENST00000356530.3	HIST1H2BE	histone cluster 1, H2be
chr9_-_2844058	0.123	ENST00000397885.2	KIAA0020	KIAA0020
chr1_-_200379180	0.122	ENST00000294740.3	ZNF281	zinc finger protein 281
chr10_-_43892668	0.121	ENST00000544000.1	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr7_-_105029812	0.115	ENST00000482897.1	SRPK2	SRSF protein kinase 2
chr12_-_7848364	0.114	ENST00000329913.3	GDF3	growth differentiation factor 3
chr8_+_110551925	0.108	ENST00000395785.2	EBAG9	estrogen receptor binding site associated, antigen, 9
chr6_+_27833034	0.103	ENST00000357320.2	HIST1H2AL	histone cluster 1, H2al
chr8_-_110620284	0.102	ENST00000529690.1	SYBU	syntabulin (syntaxin-interacting)
chr1_-_200379104	0.098	ENST00000367352.3	ZNF281	zinc finger protein 281
chr18_+_21719018	0.097	ENST00000585037.1 ENST00000415309.2 ENST00000399481.2 ENST00000577705.1 ENST00000327201.6	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr11_-_47399942	0.089	ENST00000227163.4	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_132316081	0.069	ENST00000249887.2	ACKR4	atypical chemokine receptor 4
chr17_+_34391625	0.065	ENST00000004921.3	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr11_-_76381029	0.059	ENST00000407242.2 ENST00000421973.1	LRRC32	leucine rich repeat containing 32
chr11_-_18062872	0.058	ENST00000250018.2	TPH1	tryptophan hydroxylase 1
chr18_+_6834472	0.054	ENST00000581099.1 ENST00000419673.2 ENST00000531294.1	ARHGAP28	Rho GTPase activating protein 28
chr10_-_96829246	0.053	ENST00000371270.3 ENST00000535898.1 ENST00000539050.1	CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8
chr4_-_74486347	0.043	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr10_+_15085895	0.040	ENST00000378228.3	OLAH	oleoyl-ACP hydrolase
chr22_-_17302589	0.036	ENST00000331428.5	XKR3	XK, Kell blood group complex subunit-related family, member 3
chr12_+_75874460	0.026	ENST00000266659.3	GLIPR1	GLI pathogenesis-related 1
chr20_+_54823788	0.025	ENST00000243911.2	MC3R	melanocortin 3 receptor
chr5_+_140743859	0.024	ENST00000518069.1	PCDHGA5	protocadherin gamma subfamily A, 5
chr11_+_55029628	0.023	ENST00000417545.2	TRIM48	tripartite motif containing 48
chr6_+_149539767	0.023	ENST00000606202.1 ENST00000536230.1 ENST00000445901.1	TAB2 RP1-111D6.3	TGF-beta activated kinase 1/MAP3K7 binding protein 2 RP1-111D6.3
chr11_-_76381781	0.023	ENST00000260061.5 ENST00000404995.1	LRRC32	leucine rich repeat containing 32
chr17_-_39646116	0.022	ENST00000328119.6	KRT36	keratin 36
chr10_+_47894572	0.019	ENST00000355876.5	FAM21B	family with sequence similarity 21, member B
chr14_-_20801427	0.015	ENST00000557665.1 ENST00000358932.4 ENST00000353689.4	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr8_+_145133493	0.014	ENST00000316052.5 ENST00000525936.1	EXOSC4	exosome component 4
chr11_-_113577052	0.012	ENST00000540540.1 ENST00000545579.1 ENST00000538955.1 ENST00000299882.5	TMPRSS5	transmembrane protease, serine 5
chr13_+_49280951	0.012	ENST00000282018.3	CYSLTR2	cysteinyl leukotriene receptor 2
chr11_-_47400078	0.010	ENST00000378538.3	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene
chr4_+_156680153	0.003	ENST00000502959.1 ENST00000505764.1 ENST00000507146.1 ENST00000264424.8 ENST00000503520.1	GUCY1B3	guanylate cyclase 1, soluble, beta 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	2.3	GO:0071313	cellular response to caffeine(GO:0071313)
0.4	10.9	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1	0.3	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.1	0.2	GO:0070340	cell surface pattern recognition receptor signaling pathway(GO:0002752) detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.1	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.0	0.4	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.6	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.3	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.3	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	1.0	GO:0006309	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0060122	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088) inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:1901160	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.5	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.6	GO:0032480	negative regulation of type I interferon production(GO:0032480)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	0.6	GO:0032040	small-subunit processome(GO:0032040)
0.1	2.3	GO:0005657	replication fork(GO:0005657)
0.0	0.3	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.6	GO:0001533	cornified envelope(GO:0001533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.6	10.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.7	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1	0.6	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.8	GO:0004522	ribonuclease A activity(GO:0004522)
0.1	0.3	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
0.1	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.1	1.0	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.6	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.0	GO:0016297	oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0	0.6	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)