Motif ID: SOX10_SOX15
Z-value: 2.004
Transcription factors associated with SOX10_SOX15:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
SOX10 | ENSG00000100146.12 | SOX10 |
SOX15 | ENSG00000129194.3 | SOX15 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.0 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214) |
0.6 | 3.2 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121) |
0.6 | 3.1 | GO:0051450 | myoblast proliferation(GO:0051450) |
0.6 | 2.3 | GO:0009609 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) |
0.5 | 1.9 | GO:0070842 | aggresome assembly(GO:0070842) |
0.4 | 1.5 | GO:0071313 | cellular response to caffeine(GO:0071313) |
0.4 | 2.1 | GO:0002313 | mature B cell differentiation involved in immune response(GO:0002313) |
0.3 | 2.1 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383) |
0.2 | 1.0 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
0.2 | 1.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.2 | 1.6 | GO:0043615 | astrocyte cell migration(GO:0043615) |
0.2 | 0.9 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.2 | 2.7 | GO:0050858 | negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.2 | 0.6 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.2 | 1.1 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.2 | 0.5 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
0.1 | 0.6 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
0.1 | 0.9 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.1 | 0.8 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.1 | 0.5 | GO:0001543 | ovarian follicle rupture(GO:0001543) |
0.1 | 1.5 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.1 | 0.4 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.1 | 0.4 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.1 | 0.3 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 0.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
0.1 | 0.9 | GO:0042448 | progesterone metabolic process(GO:0042448) |
0.1 | 0.4 | GO:0045938 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
0.1 | 0.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.1 | 2.1 | GO:0031648 | protein destabilization(GO:0031648) |
0.1 | 0.6 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.1 | 2.6 | GO:0042554 | superoxide anion generation(GO:0042554) |
0.1 | 0.4 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
0.1 | 0.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.1 | 0.7 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.1 | 0.3 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.6 | GO:0045008 | depyrimidination(GO:0045008) |
0.1 | 1.0 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
0.1 | 0.6 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.1 | 0.4 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
0.1 | 0.5 | GO:0045056 | transcytosis(GO:0045056) |
0.1 | 0.8 | GO:0006491 | N-glycan processing(GO:0006491) |
0.1 | 0.2 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
0.1 | 0.2 | GO:0051097 | negative regulation of helicase activity(GO:0051097) |
0.1 | 0.3 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392) |
0.1 | 0.1 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
0.1 | 0.2 | GO:0021571 | rhombomere 5 development(GO:0021571) |
0.0 | 0.4 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
0.0 | 0.4 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
0.0 | 1.1 | GO:0006825 | copper ion transport(GO:0006825) |
0.0 | 3.3 | GO:0030183 | B cell differentiation(GO:0030183) |
0.0 | 0.1 | GO:0031018 | endocrine pancreas development(GO:0031018) |
0.0 | 0.2 | GO:0010761 | fibroblast migration(GO:0010761) |
0.0 | 0.3 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
0.0 | 0.4 | GO:0072164 | ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164) |
0.0 | 0.7 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.0 | 0.2 | GO:0031033 | positive regulation of lamellipodium assembly(GO:0010592) myosin filament organization(GO:0031033) positive regulation of lamellipodium organization(GO:1902745) |
0.0 | 1.0 | GO:0051925 | obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925) |
0.0 | 0.8 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
0.0 | 0.0 | GO:0048852 | diencephalon morphogenesis(GO:0048852) |
0.0 | 0.1 | GO:0046778 | modification by virus of host mRNA processing(GO:0046778) |
0.0 | 1.2 | GO:0030325 | adrenal gland development(GO:0030325) |
0.0 | 0.9 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.2 | GO:0010042 | response to manganese ion(GO:0010042) positive regulation of glutamate secretion(GO:0014049) response to fungicide(GO:0060992) |
0.0 | 0.2 | GO:0006734 | NADH metabolic process(GO:0006734) |
0.0 | 0.2 | GO:0033145 | positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145) |
0.0 | 0.2 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
0.0 | 0.3 | GO:0051205 | protein insertion into membrane(GO:0051205) |
0.0 | 0.2 | GO:0060008 | Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009) |
0.0 | 0.1 | GO:0039656 | modulation by virus of host transcription(GO:0019056) modulation by virus of host gene expression(GO:0039656) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
0.0 | 2.1 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.0 | 0.9 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
0.0 | 0.5 | GO:0006596 | polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401) |
0.0 | 0.2 | GO:0001885 | endothelial cell development(GO:0001885) |
0.0 | 0.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
0.0 | 1.3 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) |
0.0 | 0.2 | GO:0070875 | positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875) |
0.0 | 0.2 | GO:0007512 | adult heart development(GO:0007512) |
0.0 | 0.2 | GO:1901984 | negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757) |
0.0 | 0.2 | GO:0007413 | axonal fasciculation(GO:0007413) |
0.0 | 0.1 | GO:0046831 | regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831) |
0.0 | 0.5 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
0.0 | 2.4 | GO:0007018 | microtubule-based movement(GO:0007018) |
0.0 | 0.1 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.0 | 0.3 | GO:0006301 | postreplication repair(GO:0006301) |
0.0 | 0.4 | GO:0030641 | regulation of cellular pH(GO:0030641) |
0.0 | 0.4 | GO:0042116 | macrophage activation(GO:0042116) |
0.0 | 0.7 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
0.0 | 3.6 | GO:0007601 | visual perception(GO:0007601) |
0.0 | 0.1 | GO:0006883 | cellular sodium ion homeostasis(GO:0006883) negative regulation of sodium ion transport(GO:0010766) |
0.0 | 0.5 | GO:0065003 | macromolecular complex assembly(GO:0065003) |
0.0 | 0.8 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
0.0 | 0.4 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
0.0 | 0.3 | GO:0060711 | labyrinthine layer development(GO:0060711) |
0.0 | 0.2 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.0 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
0.0 | 0.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 1.2 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 0.8 | GO:0006810 | transport(GO:0006810) |
0.0 | 0.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 0.9 | GO:0006338 | chromatin remodeling(GO:0006338) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.1 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
0.3 | 1.1 | GO:0033269 | internode region of axon(GO:0033269) |
0.2 | 1.9 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.1 | 1.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.1 | 0.7 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.1 | 1.9 | GO:0016235 | aggresome(GO:0016235) |
0.1 | 0.8 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.2 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
0.1 | 0.9 | GO:0031010 | ISWI-type complex(GO:0031010) |
0.1 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.1 | 4.0 | GO:0005626 | obsolete insoluble fraction(GO:0005626) |
0.1 | 0.2 | GO:0001650 | fibrillar center(GO:0001650) |
0.1 | 0.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.1 | 0.2 | GO:0016600 | flotillin complex(GO:0016600) synaptic cleft(GO:0043083) |
0.0 | 2.0 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 0.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.0 | 0.2 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.0 | 0.4 | GO:0043073 | germ cell nucleus(GO:0043073) |
0.0 | 1.1 | GO:0016460 | myosin II complex(GO:0016460) |
0.0 | 0.4 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 2.7 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
0.0 | 3.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.0 | 0.7 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.2 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.0 | 1.0 | GO:0030018 | Z disc(GO:0030018) |
0.0 | 0.6 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 2.3 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 1.0 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.2 | GO:0030056 | hemidesmosome(GO:0030056) |
0.0 | 1.4 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 1.9 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
0.0 | 1.6 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.2 | GO:0005858 | axonemal dynein complex(GO:0005858) axoneme part(GO:0044447) |
0.0 | 0.5 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
0.0 | 0.6 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
0.0 | 0.5 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 1.7 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.0 | 6.5 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
0.0 | 0.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.0 | 0.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
0.0 | 0.1 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
0.0 | 0.9 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
0.0 | 0.3 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.2 | GO:0035326 | enhancer binding(GO:0035326) |
0.3 | 2.0 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.3 | 1.1 | GO:0034701 | tripeptidase activity(GO:0034701) |
0.3 | 1.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.2 | 1.0 | GO:0016211 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
0.2 | 1.1 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.2 | 0.6 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
0.2 | 1.1 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.2 | 0.8 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
0.2 | 2.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.2 | 0.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.1 | 0.6 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.1 | 1.8 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 1.1 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 0.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.1 | 2.3 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.1 | 1.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.1 | 0.8 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
0.1 | 1.0 | GO:0019826 | oxygen sensor activity(GO:0019826) |
0.1 | 2.6 | GO:0043621 | protein self-association(GO:0043621) |
0.1 | 0.3 | GO:0031997 | N-terminal myristoylation domain binding(GO:0031997) |
0.1 | 0.4 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.7 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 0.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
0.1 | 0.7 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.1 | 3.1 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.1 | 2.1 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.1 | 0.5 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 0.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.1 | 0.6 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.1 | 0.4 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 0.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.1 | 0.5 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
0.1 | 0.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.1 | 0.2 | GO:0030350 | iron-responsive element binding(GO:0030350) |
0.0 | 0.8 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.0 | 0.3 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.0 | 0.2 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
0.0 | 1.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.2 | GO:0000739 | obsolete DNA strand annealing activity(GO:0000739) |
0.0 | 0.5 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.4 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.4 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
0.0 | 0.3 | GO:0016004 | phospholipase activator activity(GO:0016004) |
0.0 | 2.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.0 | 0.2 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.0 | 0.2 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
0.0 | 0.1 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 1.1 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
0.0 | 1.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.1 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
0.0 | 0.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 1.6 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
0.0 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
0.0 | 0.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.0 | 0.1 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.1 | GO:0035014 | phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
0.0 | 0.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
0.0 | 0.4 | GO:0002039 | p53 binding(GO:0002039) |
0.0 | 0.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 1.2 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 0.5 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
0.0 | 1.7 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.9 | GO:0003823 | antigen binding(GO:0003823) |
0.0 | 0.4 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
0.0 | 0.5 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.0 | 0.0 | GO:0035198 | miRNA binding(GO:0035198) |
0.0 | 0.2 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
0.0 | 0.9 | GO:0050661 | NADP binding(GO:0050661) |
0.0 | 0.1 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 5.2 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
0.0 | 1.2 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.1 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) |
0.0 | 0.4 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.0 | GO:0000976 | transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) core promoter proximal region sequence-specific DNA binding(GO:0000987) RNA polymerase II regulatory region DNA binding(GO:0001012) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) core promoter proximal region DNA binding(GO:0001159) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 0.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.4 | GO:0005080 | protein kinase C binding(GO:0005080) |
0.0 | 0.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.2 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.2 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
0.0 | 1.8 | GO:0003713 | transcription coactivator activity(GO:0003713) |
0.0 | 0.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.5 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 1.6 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
0.0 | 0.9 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 2.3 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.0 | 0.9 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
0.0 | 0.3 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.2 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |