Motif ID: SOX10_SOX15

Z-value: 2.004

Transcription factors associated with SOX10_SOX15:

Gene SymbolEntrez IDGene Name
SOX10 ENSG00000100146.12 SOX10
SOX15 ENSG00000129194.3 SOX15






Network of associatons between targets according to the STRING database.



First level regulatory network of SOX10_SOX15

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_32801825 4.310 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr8_-_80993010 3.265 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52




tumor protein D52




chr4_+_154387480 3.263 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922


KIAA0922


chr7_+_116660246 2.971 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7





suppression of tumorigenicity 7





chr1_+_200993071 2.881 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1

RP11-168O16.1

chr13_-_41593425 2.725 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr14_-_91884150 2.641 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr1_-_200992827 2.426 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr17_+_36861735 2.340 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr3_+_133118839 2.316 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr11_+_128563652 2.273 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr13_-_99959641 2.120 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chr4_-_109090106 2.083 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr5_-_175964366 2.066 ENST00000274811.4
RNF44
ring finger protein 44
chr1_+_11751748 2.012 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr20_+_60718785 1.936 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
SS18L1


synovial sarcoma translocation gene on chromosome 18-like 1


chr6_-_29527702 1.896 ENST00000377050.4
UBD
ubiquitin D
chr18_-_74207146 1.722 ENST00000443185.2
ZNF516
zinc finger protein 516
chr20_-_45985172 1.642 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr13_+_111767650 1.626 ENST00000449979.1
ENST00000370623.3
ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

chr3_-_141747950 1.564 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_151431909 1.555 ENST00000361398.3
ENST00000271715.2
POGZ

pogo transposable element with ZNF domain

chr3_+_151986709 1.547 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1



muscleblind-like splicing regulator 1



chr11_+_125496619 1.529 ENST00000532669.1
ENST00000278916.3
CHEK1

checkpoint kinase 1

chr10_+_11206925 1.503 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr20_-_4804244 1.419 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_+_192544857 1.381 ENST00000367459.3
ENST00000469578.2
RGS1

regulator of G-protein signaling 1

chr2_+_232573208 1.343 ENST00000409115.3
PTMA
prothymosin, alpha
chrX_+_129305623 1.341 ENST00000257017.4
RAB33A
RAB33A, member RAS oncogene family
chr2_+_70056762 1.321 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr3_-_124839648 1.290 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr14_-_65409502 1.278 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr9_-_130712995 1.268 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr10_+_35484793 1.260 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr15_-_70388943 1.240 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chr7_+_29234028 1.219 ENST00000222792.6
CHN2
chimerin 2
chr6_+_119215308 1.172 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr2_+_232573222 1.137 ENST00000341369.7
ENST00000409683.1
PTMA

prothymosin, alpha

chr18_+_72201829 1.115 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr4_-_109089573 1.110 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr18_-_74728998 1.102 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP










myelin basic protein










chr2_+_32288725 1.092 ENST00000315285.3
SPAST
spastin
chr8_+_21777159 1.083 ENST00000434536.1
ENST00000252512.9
XPO7

exportin 7

chr9_+_137218362 1.063 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr3_-_148939835 1.053 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr14_-_65409438 1.037 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr7_+_23146271 1.032 ENST00000545771.1
KLHL7
kelch-like family member 7
chr16_+_71660079 1.001 ENST00000565261.1
ENST00000268485.3
ENST00000299952.4
MARVELD3


MARVEL domain containing 3


chr2_+_27070964 0.958 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr14_-_51027838 0.944 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_67498538 0.937 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_122720681 0.927 ENST00000368455.4
ENST00000452194.1
HSF2

heat shock transcription factor 2

chr20_-_45984401 0.923 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr4_+_74301880 0.915 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr17_+_27071002 0.897 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4



TNF receptor-associated factor 4



chr2_+_32288657 0.885 ENST00000345662.1
SPAST
spastin
chrX_+_37639264 0.877 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr3_+_111260954 0.855 ENST00000283285.5
CD96
CD96 molecule
chr14_-_35344093 0.852 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr14_-_71107921 0.826 ENST00000500016.1
ENST00000553982.1
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
chr12_-_42631529 0.825 ENST00000548917.1
YAF2
YY1 associated factor 2
chrX_+_70503433 0.806 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr7_+_29234101 0.791 ENST00000435288.2
CHN2
chimerin 2
chr2_+_120517174 0.789 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr15_+_75074410 0.781 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_+_89184868 0.769 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr12_-_102874416 0.755 ENST00000392904.1
ENST00000337514.6
IGF1

insulin-like growth factor 1 (somatomedin C)

chr4_-_186877502 0.750 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr7_+_111846643 0.747 ENST00000361822.3
ZNF277
zinc finger protein 277
chr2_-_39348137 0.746 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr6_+_64282447 0.745 ENST00000370650.2
ENST00000578299.1
PTP4A1

protein tyrosine phosphatase type IVA, member 1

chr8_-_8751068 0.737 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr15_-_50647274 0.736 ENST00000543881.1
GABPB1
GA binding protein transcription factor, beta subunit 1
chr11_+_67007518 0.734 ENST00000530342.1
ENST00000308783.5
KDM2A

lysine (K)-specific demethylase 2A

chr5_-_65017921 0.724 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr12_-_102874378 0.724 ENST00000456098.1
IGF1
insulin-like growth factor 1 (somatomedin C)
chr18_+_6729698 0.708 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr1_+_183774240 0.704 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr11_+_63706444 0.703 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr12_-_102872317 0.700 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_+_37639302 0.692 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr7_+_50344289 0.692 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1







IKAROS family zinc finger 1 (Ikaros)







chr3_+_173116225 0.690 ENST00000457714.1
NLGN1
neuroligin 1
chr4_+_113152881 0.683 ENST00000274000.5
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr7_+_20370746 0.678 ENST00000222573.4
ITGB8
integrin, beta 8
chr20_+_61448376 0.671 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chrX_-_32173579 0.670 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr6_-_64029879 0.669 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN


lengsin, lens protein with glutamine synthetase domain


chr8_+_81397876 0.650 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chrX_-_110655306 0.650 ENST00000371993.2
DCX
doublecortin
chr15_-_50647370 0.646 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GABPB1


GA binding protein transcription factor, beta subunit 1


chr13_+_111365602 0.644 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr20_-_30795511 0.633 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr16_-_73082274 0.624 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr8_+_107738240 0.617 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr3_-_167813132 0.612 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr20_+_48884002 0.612 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3

RP11-290F20.3

chr4_+_113152978 0.607 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr17_+_75447326 0.607 ENST00000591088.1
SEPT9
septin 9
chr8_+_81398444 0.597 ENST00000455036.3
ENST00000426744.2
ZBTB10

zinc finger and BTB domain containing 10

chr2_+_10262857 0.591 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr1_-_151431647 0.586 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chr7_-_22233442 0.581 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_-_114355083 0.578 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr6_+_87865262 0.572 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr8_-_70745575 0.562 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_27114577 0.560 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr7_-_148581251 0.556 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2


enhancer of zeste homolog 2 (Drosophila)


chr1_+_66458072 0.555 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_12419703 0.552 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr1_+_244998602 0.547 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr15_+_57210961 0.540 ENST00000557843.1
TCF12
transcription factor 12
chr6_+_72596604 0.534 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr17_+_64961026 0.534 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr11_-_6677018 0.517 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr2_-_152955537 0.513 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr7_-_99679324 0.507 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3






zinc finger protein 3






chr7_-_140178726 0.506 ENST00000480552.1
MKRN1
makorin ring finger protein 1
chr12_-_102874102 0.504 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_+_39509163 0.503 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP


myelin-associated oligodendrocyte basic protein


chr6_+_108881012 0.497 ENST00000343882.6
FOXO3
forkhead box O3
chrX_-_110655391 0.497 ENST00000356915.2
ENST00000356220.3
DCX

doublecortin

chr17_-_76713100 0.497 ENST00000585509.1
CYTH1
cytohesin 1
chr1_-_46152174 0.493 ENST00000290795.3
ENST00000355105.3
GPBP1L1

GC-rich promoter binding protein 1-like 1

chr7_+_44788430 0.491 ENST00000457123.1
ENST00000309315.4
ZMIZ2

zinc finger, MIZ-type containing 2

chr17_-_73389737 0.482 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr10_+_35415978 0.477 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr3_-_65583561 0.475 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_-_102323489 0.469 ENST00000361236.3
TMEM123
transmembrane protein 123
chr11_-_102323740 0.468 ENST00000398136.2
TMEM123
transmembrane protein 123
chr4_+_76649797 0.466 ENST00000538159.1
ENST00000514213.2
USO1

USO1 vesicle transport factor

chr15_-_50647347 0.462 ENST00000220429.8
ENST00000429662.2
GABPB1

GA binding protein transcription factor, beta subunit 1

chr2_+_162272605 0.459 ENST00000389554.3
TBR1
T-box, brain, 1
chr5_+_43603229 0.457 ENST00000344920.4
ENST00000512996.2
NNT

nicotinamide nucleotide transhydrogenase

chrX_-_135962876 0.454 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX



RNA binding motif protein, X-linked



chr2_-_10588630 0.454 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr5_-_115910091 0.454 ENST00000257414.8
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_+_104359641 0.447 ENST00000537100.1
TDG
thymine-DNA glycosylase
chr12_+_15475462 0.446 ENST00000543886.1
ENST00000348962.2
PTPRO

protein tyrosine phosphatase, receptor type, O

chr17_-_79881408 0.441 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr10_+_35415719 0.441 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr14_-_31495569 0.440 ENST00000357479.5
ENST00000355683.5
STRN3

striatin, calmodulin binding protein 3

chr6_+_114178512 0.437 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr12_-_109027643 0.433 ENST00000388962.3
ENST00000550948.1
SELPLG

selectin P ligand

chr1_-_234614849 0.432 ENST00000040877.1
TARBP1
TAR (HIV-1) RNA binding protein 1
chr5_+_43602750 0.430 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT


nicotinamide nucleotide transhydrogenase


chr3_+_39509070 0.430 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP





myelin-associated oligodendrocyte basic protein





chr12_-_102874330 0.426 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr19_-_18717627 0.421 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr16_-_4852915 0.421 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr17_+_7590734 0.420 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr7_+_87563557 0.417 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22





ADAM metallopeptidase domain 22





chr11_+_46402744 0.414 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr20_-_23066953 0.414 ENST00000246006.4
CD93
CD93 molecule
chr5_-_115872142 0.411 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr15_+_92937144 0.405 ENST00000539113.1
ENST00000555434.1
ST8SIA2

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

chr11_+_46402583 0.402 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr4_+_118955500 0.402 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr15_+_92937058 0.401 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr3_-_46904946 0.400 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_+_52311398 0.400 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr9_-_120177342 0.400 ENST00000361209.2
ASTN2
astrotactin 2
chr3_-_48470838 0.400 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr12_-_102591604 0.399 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr12_+_124997766 0.396 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr2_+_169312725 0.394 ENST00000392687.4
CERS6
ceramide synthase 6
chr12_-_122985494 0.393 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chr9_-_73483958 0.392 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
TRPM3



transient receptor potential cation channel, subfamily M, member 3



chr3_-_46904918 0.390 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr19_+_4007644 0.390 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr7_+_111846741 0.386 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
ZNF277


zinc finger protein 277


chr4_+_41614720 0.384 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_14075865 0.377 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr17_-_49124230 0.377 ENST00000510283.1
ENST00000510855.1
SPAG9

sperm associated antigen 9

chr5_-_150521192 0.376 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr18_+_32558208 0.366 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr17_+_26698677 0.366 ENST00000457710.3
SARM1
sterile alpha and TIR motif containing 1
chr11_+_46402482 0.364 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_131352152 0.362 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr16_+_84801852 0.361 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr6_-_11232891 0.355 ENST00000379433.5
ENST00000379446.5
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr20_-_62284766 0.354 ENST00000370053.1
STMN3
stathmin-like 3
chr1_-_115053781 0.353 ENST00000358465.2
ENST00000369543.2
TRIM33

tripartite motif containing 33

chr3_+_52719936 0.345 ENST00000418458.1
ENST00000394799.2
GNL3

guanine nucleotide binding protein-like 3 (nucleolar)

chr14_+_22984601 0.342 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr17_-_73389854 0.336 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
GRB2


growth factor receptor-bound protein 2


chr2_+_198669365 0.335 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr14_+_97263641 0.329 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr2_-_47572105 0.326 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr7_-_25268104 0.322 ENST00000222674.2
NPVF
neuropeptide VF precursor
chr19_+_47105309 0.319 ENST00000599839.1
ENST00000596362.1
CALM3

calmodulin 3 (phosphorylase kinase, delta)

chr14_-_58618896 0.319 ENST00000267485.7
C14orf37
chromosome 14 open reading frame 37
chrX_-_11284095 0.319 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr3_+_183353356 0.316 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
KLHL24








kelch-like family member 24








chr12_-_122985067 0.309 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr5_-_111092930 0.308 ENST00000257435.7
NREP
neuronal regeneration related protein
chr1_+_66797687 0.308 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B


phosphodiesterase 4B, cAMP-specific


chr6_+_10556215 0.307 ENST00000316170.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_-_128568721 0.306 ENST00000322313.4
ENST00000393006.1
ENST00000409658.3
ENST00000436787.1
WDR33



WD repeat domain 33



chr6_+_83777374 0.306 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1


dopey family member 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214)
0.6 3.2 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.6 3.1 GO:0051450 myoblast proliferation(GO:0051450)
0.6 2.3 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.5 1.9 GO:0070842 aggresome assembly(GO:0070842)
0.4 1.5 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 2.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.3 2.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.2 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.2 1.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.2 1.6 GO:0043615 astrocyte cell migration(GO:0043615)
0.2 0.9 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 2.7 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 1.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.2 0.5 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.6 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.9 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.5 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.9 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.4 GO:0045938 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.9 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.1 GO:0031648 protein destabilization(GO:0031648)
0.1 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 2.6 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.6 GO:0045008 depyrimidination(GO:0045008)
0.1 1.0 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.5 GO:0045056 transcytosis(GO:0045056)
0.1 0.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1 0.1 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 1.1 GO:0006825 copper ion transport(GO:0006825)
0.0 3.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.2 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.3 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.4 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0031033 positive regulation of lamellipodium assembly(GO:0010592) myosin filament organization(GO:0031033) positive regulation of lamellipodium organization(GO:1902745)
0.0 1.0 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.0 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.1 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.0 1.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0010042 response to manganese ion(GO:0010042) positive regulation of glutamate secretion(GO:0014049) response to fungicide(GO:0060992)
0.0 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.2 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.2 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.1 GO:0039656 modulation by virus of host transcription(GO:0019056) modulation by virus of host gene expression(GO:0039656) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 2.1 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.5 GO:0006596 polyamine biosynthetic process(GO:0006596) cellular biogenic amine biosynthetic process(GO:0042401)
0.0 0.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.4 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 1.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.5 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 2.4 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.4 GO:0042116 macrophage activation(GO:0042116)
0.0 0.7 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 3.6 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0006883 cellular sodium ion homeostasis(GO:0006883) negative regulation of sodium ion transport(GO:0010766)
0.0 0.5 GO:0065003 macromolecular complex assembly(GO:0065003)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 0.2 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759) menarche(GO:0042696)
0.0 0.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.2 GO:0051028 mRNA transport(GO:0051028)
0.0 0.8 GO:0006810 transport(GO:0006810)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 1.1 GO:0033269 internode region of axon(GO:0033269)
0.2 1.9 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 1.9 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 1.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.1 0.9 GO:0031010 ISWI-type complex(GO:0031010)
0.1 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.0 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 0.2 GO:0001650 fibrillar center(GO:0001650)
0.1 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600) synaptic cleft(GO:0043083)
0.0 2.0 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.0 1.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 2.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 3.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.0 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.0 0.5 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.6 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.7 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 6.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.3 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0035326 enhancer binding(GO:0035326)
0.3 2.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 1.1 GO:0034701 tripeptidase activity(GO:0034701)
0.3 1.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 1.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.2 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.6 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.2 1.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.8 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.2 2.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 1.8 GO:0070628 proteasome binding(GO:0070628)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 2.6 GO:0043621 protein self-association(GO:0043621)
0.1 0.3 GO:0031997 N-terminal myristoylation domain binding(GO:0031997)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 3.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.5 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.1 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.2 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.7 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.9 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 5.2 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.0 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976) RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) core promoter proximal region sequence-specific DNA binding(GO:0000987) RNA polymerase II regulatory region DNA binding(GO:0001012) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) core promoter proximal region DNA binding(GO:0001159) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.6 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 2.3 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway