Motif ID: SOX5

Z-value: 2.567


Transcription factors associated with SOX5:

Gene SymbolEntrez IDGene Name
SOX5 ENSG00000134532.11 SOX5



Activity profile for motif SOX5.

activity profile for motif SOX5


Sorted Z-values histogram for motif SOX5

Sorted Z-values for motif SOX5



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_6233828 4.897 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr7_-_111846435 4.351 ENST00000437633.1
ENST00000428084.1
DOCK4

dedicator of cytokinesis 4

chr6_+_12290586 3.967 ENST00000379375.5
EDN1
endothelin 1
chr11_+_46402583 3.130 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_86043921 2.920 ENST00000535924.2
DDAH1
dimethylarginine dimethylaminohydrolase 1
chrY_+_15016013 2.858 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chrX_+_15525426 2.843 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr11_+_46402744 2.778 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_99594948 2.761 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr3_-_99595037 2.578 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr2_-_188312971 2.569 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL


calcitonin receptor-like


chr7_-_27205136 2.479 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr7_-_131241361 2.228 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr4_-_186732048 2.178 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr4_-_101439148 2.136 ENST00000511970.1
ENST00000502569.1
ENST00000305864.3
EMCN


endomucin


chr4_-_101439242 2.111 ENST00000296420.4
EMCN
endomucin
chr11_+_46402482 2.096 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_8686479 2.094 ENST00000544814.1
ENST00000427408.1
SSUH2

ssu-2 homolog (C. elegans)

chrX_-_99891796 2.024 ENST00000373020.4
TSPAN6
tetraspanin 6
chr2_-_133427767 1.951 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr7_-_47621736 1.856 ENST00000311160.9
TNS3
tensin 3
chr18_-_52989217 1.834 ENST00000570287.2
TCF4
transcription factor 4
chr11_-_89224638 1.810 ENST00000535633.1
ENST00000263317.4
NOX4

NADPH oxidase 4

chr20_-_45985172 1.763 ENST00000536340.1
ZMYND8
zinc finger, MYND-type containing 8
chr7_-_11871815 1.717 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr21_-_39870339 1.683 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chr2_-_160473114 1.672 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr10_-_116444371 1.650 ENST00000533213.2
ENST00000369252.4
ABLIM1

actin binding LIM protein 1

chr14_-_89883412 1.506 ENST00000557258.1
FOXN3
forkhead box N3
chr6_+_89790490 1.496 ENST00000336032.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr18_-_52989525 1.492 ENST00000457482.3
TCF4
transcription factor 4
chr12_-_71031185 1.458 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr11_+_19799327 1.458 ENST00000540292.1
NAV2
neuron navigator 2
chr2_-_192711968 1.450 ENST00000304141.4
SDPR
serum deprivation response
chr6_+_89790459 1.445 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr12_-_71003568 1.432 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB




protein tyrosine phosphatase, receptor type, B




chr18_-_53177984 1.405 ENST00000543082.1
TCF4
transcription factor 4
chr1_+_81771806 1.371 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr11_+_128563948 1.347 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_-_12677714 1.345 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr5_-_16936340 1.334 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr6_-_128841503 1.334 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr11_+_19798964 1.266 ENST00000527559.2
NAV2
neuron navigator 2
chr11_+_128563652 1.250 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr3_+_173116225 1.201 ENST00000457714.1
NLGN1
neuroligin 1
chr12_-_89746173 1.201 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr20_-_45985464 1.163 ENST00000458360.2
ENST00000262975.4
ZMYND8

zinc finger, MYND-type containing 8

chr20_-_45981138 1.146 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr14_+_61654271 1.143 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr14_-_55878538 1.115 ENST00000247178.5
ATG14
autophagy related 14
chr11_+_128562372 1.112 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr10_-_13523073 1.105 ENST00000440282.1
BEND7
BEN domain containing 7
chr14_+_77228532 1.072 ENST00000167106.4
ENST00000554237.1
VASH1

vasohibin 1

chr20_-_45985414 1.030 ENST00000461685.1
ENST00000372023.3
ENST00000540497.1
ENST00000435836.1
ENST00000471951.2
ENST00000352431.2
ENST00000396281.4
ENST00000355972.4
ENST00000360911.3
ZMYND8








zinc finger, MYND-type containing 8








chr1_+_10271674 1.015 ENST00000377086.1
KIF1B
kinesin family member 1B
chr3_+_25469802 0.996 ENST00000330688.4
RARB
retinoic acid receptor, beta
chr8_-_93115445 0.985 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_-_71031220 0.961 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr2_-_70475701 0.887 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr11_-_35441524 0.872 ENST00000395750.1
ENST00000449068.1
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr2_-_70475730 0.852 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1


TIA1 cytotoxic granule-associated RNA binding protein


chrX_-_64196376 0.848 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr3_-_114343039 0.823 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_102314161 0.816 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr11_-_102323489 0.803 ENST00000361236.3
TMEM123
transmembrane protein 123
chr7_+_29519486 0.797 ENST00000409041.4
CHN2
chimerin 2
chr6_-_152957944 0.788 ENST00000423061.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr10_+_97803151 0.782 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ



cyclin J



chr12_+_52306113 0.774 ENST00000547400.1
ENST00000550683.1
ENST00000419526.2
ACVRL1


activin A receptor type II-like 1


chr3_-_114790179 0.770 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr11_-_102323740 0.759 ENST00000398136.2
TMEM123
transmembrane protein 123
chr7_+_134576317 0.755 ENST00000424922.1
ENST00000495522.1
CALD1

caldesmon 1

chr11_-_35440796 0.753 ENST00000278379.3
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_33661382 0.752 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrX_+_107683096 0.734 ENST00000328300.6
ENST00000361603.2
COL4A5

collagen, type IV, alpha 5

chr15_+_66994561 0.732 ENST00000288840.5
SMAD6
SMAD family member 6
chr3_-_129407535 0.730 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr10_+_99079008 0.725 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr2_-_160472952 0.703 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B



bromodomain adjacent to zinc finger domain, 2B



chr9_+_27109133 0.691 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chr3_-_11685345 0.686 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr12_-_498620 0.684 ENST00000399788.2
ENST00000382815.4
KDM5A

lysine (K)-specific demethylase 5A

chr16_-_73093597 0.669 ENST00000397992.5
ZFHX3
zinc finger homeobox 3
chr3_+_25469724 0.665 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr2_+_86668464 0.657 ENST00000409064.1
KDM3A
lysine (K)-specific demethylase 3A
chr7_+_134576151 0.656 ENST00000393118.2
CALD1
caldesmon 1
chr7_+_134551583 0.647 ENST00000435928.1
CALD1
caldesmon 1
chr7_+_111846643 0.621 ENST00000361822.3
ZNF277
zinc finger protein 277
chr8_-_57123815 0.611 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1


pleiomorphic adenoma gene 1


chr17_+_37894570 0.599 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr14_-_92413727 0.584 ENST00000267620.10
FBLN5
fibulin 5
chr12_+_53443680 0.577 ENST00000314250.6
ENST00000451358.1
TENC1

tensin like C1 domain containing phosphatase (tensin 2)

chr10_+_104535994 0.575 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr20_-_45984401 0.571 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr12_-_111926342 0.564 ENST00000389154.3
ATXN2
ataxin 2
chr1_+_163038565 0.563 ENST00000421743.2
RGS4
regulator of G-protein signaling 4
chr9_-_14314518 0.560 ENST00000397581.2
NFIB
nuclear factor I/B
chr9_-_124989804 0.527 ENST00000373755.2
ENST00000373754.2
LHX6

LIM homeobox 6

chr17_+_37894179 0.526 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7


growth factor receptor-bound protein 7


chr1_-_243418621 0.523 ENST00000366544.1
ENST00000366543.1
CEP170

centrosomal protein 170kDa

chr18_+_3451646 0.518 ENST00000345133.5
ENST00000330513.5
ENST00000549546.1
TGIF1


TGFB-induced factor homeobox 1


chr1_+_150337100 0.514 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr9_-_15510989 0.498 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1



PC4 and SFRS1 interacting protein 1



chr9_-_14314566 0.497 ENST00000397579.2
NFIB
nuclear factor I/B
chr12_+_53443963 0.492 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
TENC1


tensin like C1 domain containing phosphatase (tensin 2)


chr2_-_26205340 0.491 ENST00000264712.3
KIF3C
kinesin family member 3C
chr17_+_67498538 0.488 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_+_179159813 0.484 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr22_-_36236265 0.463 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr2_+_30569506 0.458 ENST00000421976.2
AC109642.1
AC109642.1
chrX_+_123094369 0.442 ENST00000455404.1
ENST00000218089.9
STAG2

stromal antigen 2

chr1_+_150337144 0.439 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2


regulation of nuclear pre-mRNA domain containing 2


chr1_-_150241341 0.438 ENST00000369109.3
ENST00000414276.2
ENST00000236017.5
APH1A


APH1A gamma secretase subunit


chrX_-_100872911 0.435 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
ARMCX6


armadillo repeat containing, X-linked 6


chr4_-_76598326 0.429 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr9_-_37465396 0.421 ENST00000307750.4
ZBTB5
zinc finger and BTB domain containing 5
chr11_+_111807863 0.415 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr11_-_35441597 0.403 ENST00000395753.1
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_189507460 0.398 ENST00000434928.1
TP63
tumor protein p63
chr1_+_167298281 0.364 ENST00000367862.5
POU2F1
POU class 2 homeobox 1
chr1_-_151119087 0.361 ENST00000341697.3
ENST00000368914.3
SEMA6C

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C

chr6_+_37137939 0.357 ENST00000373509.5
PIM1
pim-1 oncogene
chr22_+_38093005 0.352 ENST00000406386.3
TRIOBP
TRIO and F-actin binding protein
chrX_-_50557302 0.350 ENST00000289292.7
SHROOM4
shroom family member 4
chr1_-_243418344 0.341 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr10_+_63661053 0.341 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr14_+_23790655 0.337 ENST00000397276.2
PABPN1
poly(A) binding protein, nuclear 1
chr2_+_58655461 0.326 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr1_+_147013182 0.307 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr5_-_175964366 0.307 ENST00000274811.4
RNF44
ring finger protein 44
chr8_-_33424636 0.302 ENST00000256257.1
RNF122
ring finger protein 122
chr6_-_99873145 0.298 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr7_+_29519662 0.295 ENST00000424025.2
ENST00000439711.2
ENST00000421775.2
CHN2


chimerin 2


chr18_+_3451584 0.285 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr16_+_3704822 0.282 ENST00000414110.2
DNASE1
deoxyribonuclease I
chr4_+_110749143 0.279 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr6_+_119215308 0.276 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr7_-_32931387 0.276 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr8_-_72274467 0.275 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr20_+_32150140 0.267 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
CBFA2T2




core-binding factor, runt domain, alpha subunit 2; translocated to, 2




chr1_+_33116743 0.251 ENST00000414241.3
ENST00000373493.5
RBBP4

retinoblastoma binding protein 4

chr6_+_56954867 0.245 ENST00000370708.4
ENST00000370702.1
ZNF451

zinc finger protein 451

chr4_+_160188889 0.242 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr11_-_82708435 0.234 ENST00000525117.1
ENST00000532548.1
RAB30

RAB30, member RAS oncogene family

chr12_+_49761273 0.233 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
SPATS2




spermatogenesis associated, serine-rich 2




chr11_-_82708519 0.225 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr15_-_37391507 0.221 ENST00000557796.2
ENST00000397620.2
MEIS2

Meis homeobox 2

chr3_-_48754599 0.220 ENST00000413654.1
ENST00000454335.1
ENST00000440424.1
ENST00000449610.1
ENST00000443964.1
ENST00000417896.1
ENST00000413298.1
ENST00000449563.1
ENST00000443853.1
ENST00000437427.1
ENST00000446860.1
ENST00000412850.1
ENST00000424035.1
ENST00000340879.4
ENST00000431721.2
ENST00000434860.1
ENST00000328631.5
ENST00000432678.2
IP6K2

















inositol hexakisphosphate kinase 2

















chr15_-_37391614 0.220 ENST00000219869.9
MEIS2
Meis homeobox 2
chr4_-_2264015 0.219 ENST00000337190.2
MXD4
MAX dimerization protein 4
chrX_-_50557014 0.216 ENST00000376020.2
SHROOM4
shroom family member 4
chr1_+_15272271 0.216 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr6_+_126240442 0.213 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7


nuclear receptor coactivator 7


chr9_+_27109392 0.202 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chrX_+_123094672 0.201 ENST00000354548.5
ENST00000458700.1
STAG2

stromal antigen 2

chr3_-_52486841 0.199 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr12_-_91451758 0.198 ENST00000266719.3
KERA
keratocan
chr1_-_53018654 0.190 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11




zinc finger, CCHC domain containing 11




chr4_+_41614720 0.189 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr12_+_49761224 0.188 ENST00000553127.1
ENST00000321898.6
SPATS2

spermatogenesis associated, serine-rich 2

chr1_+_228337553 0.187 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr12_+_52445191 0.185 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr1_-_217250231 0.184 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr12_-_51477333 0.183 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2



cysteine-serine-rich nuclear protein 2



chr15_-_86338100 0.179 ENST00000536947.1
KLHL25
kelch-like family member 25
chr4_+_41614909 0.177 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr1_-_40367530 0.175 ENST00000372816.2
ENST00000372815.1
MYCL

v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

chr12_-_122985067 0.171 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr6_-_79944336 0.170 ENST00000344726.5
ENST00000275036.7
HMGN3

high mobility group nucleosomal binding domain 3

chr12_-_122985494 0.169 ENST00000336229.4
ZCCHC8
zinc finger, CCHC domain containing 8
chrX_+_107288197 0.167 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr14_+_23790690 0.165 ENST00000556821.1
PABPN1
poly(A) binding protein, nuclear 1
chr9_-_123239632 0.163 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr10_+_70480963 0.152 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1







cell division cycle and apoptosis regulator 1







chr16_+_31085714 0.145 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
ZNF646


zinc finger protein 646


chr1_-_8000872 0.140 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr15_+_75074410 0.136 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_-_208989225 0.135 ENST00000264376.4
CRYGD
crystallin, gamma D
chrX_+_107288239 0.135 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr17_-_39041479 0.131 ENST00000167588.3
KRT20
keratin 20
chr10_-_99094458 0.127 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr5_-_147162078 0.127 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_+_170581213 0.122 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr3_+_89156799 0.118 ENST00000452448.2
ENST00000494014.1
EPHA3

EPH receptor A3

chr15_-_86338134 0.115 ENST00000337975.5
KLHL25
kelch-like family member 25
chr11_-_115375107 0.114 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr8_-_72274095 0.112 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr2_-_55277654 0.109 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr14_+_22748980 0.106 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr19_+_38397839 0.104 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr1_-_167883327 0.098 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10


adenylate cyclase 10 (soluble)


chr2_-_86422523 0.093 ENST00000442664.2
ENST00000409051.2
ENST00000449247.2
IMMT


inner membrane protein, mitochondrial


chr5_-_134871639 0.089 ENST00000314744.4
NEUROG1
neurogenin 1
chr1_-_28177255 0.085 ENST00000601459.1
AL109927.1
HCG2032222; PRO2047; Uncharacterized protein
chr15_-_34610962 0.075 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr1_-_226926864 0.074 ENST00000429204.1
ENST00000366784.1
ITPKB

inositol-trisphosphate 3-kinase B

chrX_+_70503433 0.072 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
NONO



non-POU domain containing, octamer-binding



chr2_-_55277692 0.070 ENST00000394611.2
RTN4
reticulon 4
chr9_-_130712995 0.067 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr15_+_75074385 0.062 ENST00000220003.9
CSK
c-src tyrosine kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0060024 rhythmic synaptic transmission(GO:0060024) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.4 2.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.4 1.2 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.3 1.0 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.3 2.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 2.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 1.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.2 2.9 GO:0000052 citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527)
0.2 1.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.2 7.8 GO:0030325 adrenal gland development(GO:0030325)
0.2 0.8 GO:0001955 blood vessel maturation(GO:0001955)
0.2 0.5 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.2 3.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.6 GO:0060394 obsolete positive regulation of S phase of mitotic cell cycle(GO:0045750) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.6 GO:0070265 necrotic cell death(GO:0070265)
0.1 0.5 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) lens induction in camera-type eye(GO:0060235) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0010761 fibroblast migration(GO:0010761)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.7 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.8 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.5 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1 1.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.1 0.2 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.1 1.8 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 1.6 GO:0048566 embryonic digestive tract development(GO:0048566)
0.1 1.0 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1 2.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.4 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1 0.6 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.6 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576) otolith development(GO:0048840)
0.0 0.5 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 4.7 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.9 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:2000121 regulation of superoxide metabolic process(GO:0090322) regulation of removal of superoxide radicals(GO:2000121)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.5 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220) membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 1.0 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 2.6 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 3.7 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 2.3 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0071280 epithelial fluid transport(GO:0042045) cellular response to copper ion(GO:0071280) cellular response to mercury ion(GO:0071288)
0.0 0.3 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 2.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.1 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 3.8 GO:0032420 stereocilium(GO:0032420)
0.2 2.0 GO:0030673 axolemma(GO:0030673)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 5.5 GO:0016459 myosin complex(GO:0016459)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 7.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.5 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 1.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0004948 calcitonin receptor activity(GO:0004948)
0.8 4.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.6 2.9 GO:0016403 dimethylargininase activity(GO:0016403)
0.5 1.4 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 4.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.3 2.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 1.8 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.8 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 5.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 4.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 1.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 1.4 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.7 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.6 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 7.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 2.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 5.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0051015 actin filament binding(GO:0051015)
0.0 2.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 1.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.0 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction