Motif ID: SOX7

Z-value: 0.910


Transcription factors associated with SOX7:

Gene SymbolEntrez IDGene Name
SOX7 ENSG00000171056.6 SOX7
SOX7 ENSG00000258724.1 SOX7



Activity profile for motif SOX7.

activity profile for motif SOX7


Sorted Z-values histogram for motif SOX7

Sorted Z-values for motif SOX7



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_95158644 1.500 ENST00000237858.6
 GLRX
glutaredoxin (thioltransferase)
chr22_+_23101182 1.317 ENST00000390312.2
 IGLV2-14
immunoglobulin lambda variable 2-14
chr14_-_106573756 1.172 ENST00000390601.2
 IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr5_-_95158375 0.961 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
 GLRX



glutaredoxin (thioltransferase)



chr11_+_7618413 0.872 ENST00000528883.1
 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr21_-_15918618 0.688 ENST00000400564.1
ENST00000400566.1
 SAMSN1

SAM domain, SH3 domain and nuclear localization signals 1

chr21_+_34144411 0.565 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
 C21orf49



chromosome 21 open reading frame 49



chr6_-_111804905 0.524 ENST00000358835.3
ENST00000435970.1
 REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr8_-_102803163 0.513 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD






neurocalcin delta






chr1_+_100598691 0.502 ENST00000370143.1
ENST00000370141.2
 TRMT13

tRNA methyltransferase 13 homolog (S. cerevisiae)

chr12_-_90049878 0.460 ENST00000359142.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_90049828 0.414 ENST00000261173.2
ENST00000348959.3
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr16_+_33020496 0.395 ENST00000565407.2
 IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr19_-_22379753 0.336 ENST00000397121.2
 ZNF676
zinc finger protein 676
chr16_-_33647696 0.322 ENST00000558425.1
ENST00000569103.2
 RP11-812E19.9

Uncharacterized protein

chr8_+_77593448 0.305 ENST00000521891.2
 ZFHX4
zinc finger homeobox 4
chr10_+_5005445 0.290 ENST00000380872.4
 AKR1C1
aldo-keto reductase family 1, member C1
chr12_-_57443886 0.268 ENST00000300119.3
 MYO1A
myosin IA
chr6_+_131894284 0.255 ENST00000368087.3
ENST00000356962.2
 ARG1

arginase 1

chr10_-_5046042 0.252 ENST00000421196.3
ENST00000455190.1
 AKR1C2

aldo-keto reductase family 1, member C2

chr2_-_166930131 0.177 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chrX_+_69353284 0.171 ENST00000342206.6
ENST00000356413.4
 IGBP1

immunoglobulin (CD79A) binding protein 1

chr6_+_42531798 0.152 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
 UBR2


ubiquitin protein ligase E3 component n-recognin 2


chr18_+_32820990 0.147 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
 ZNF397





zinc finger protein 397





chr1_+_10509971 0.145 ENST00000320498.4
 CORT
cortistatin
chr5_+_175511859 0.120 ENST00000503724.2
ENST00000253490.4
 FAM153B

family with sequence similarity 153, member B

chr12_-_58027138 0.115 ENST00000341156.4
 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr9_-_70465758 0.104 ENST00000489273.1
 CBWD5
COBW domain containing 5
chr10_+_96162242 0.104 ENST00000225235.4
 TBC1D12
TBC1 domain family, member 12
chr17_-_66951474 0.099 ENST00000269080.2
 ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr8_+_12803176 0.088 ENST00000524591.2
 KIAA1456
KIAA1456
chr4_+_76995855 0.081 ENST00000355810.4
ENST00000349321.3
 ART3

ADP-ribosyltransferase 3

chr6_+_150690028 0.079 ENST00000229447.5
ENST00000344419.3
 IYD

iodotyrosine deiodinase

chr6_+_150690133 0.071 ENST00000392255.3
ENST00000500320.3
 IYD

iodotyrosine deiodinase

chr15_+_59439899 0.070 ENST00000599727.1
 C15ORF31
C15ORF31
chr6_+_29555683 0.060 ENST00000383640.2
 OR2H2
olfactory receptor, family 2, subfamily H, member 2
chr9_+_105757590 0.050 ENST00000374798.3
ENST00000487798.1
 CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr8_-_19459993 0.049 ENST00000454498.2
ENST00000520003.1
 CSGALNACT1

chondroitin sulfate N-acetylgalactosaminyltransferase 1

chr1_+_11724167 0.046 ENST00000376753.4
 FBXO6
F-box protein 6
chr1_-_54303934 0.045 ENST00000537333.1
 NDC1
NDC1 transmembrane nucleoporin
chr4_-_47983519 0.033 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
 CNGA1


cyclic nucleotide gated channel alpha 1


chr5_+_161494521 0.029 ENST00000356592.3
 GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_-_88285309 0.020 ENST00000420840.2
 RGPD2
RANBP2-like and GRIP domain containing 2
chr6_-_46048116 0.015 ENST00000185206.6
 CLIC5
chloride intracellular channel 5
chr6_-_132910877 0.007 ENST00000258034.2
 TAAR5
trace amine associated receptor 5
chr14_+_50291993 0.005 ENST00000595378.1
 AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr16_-_20364030 0.003 ENST00000396134.2
ENST00000573567.1
ENST00000570757.1
ENST00000424589.1
ENST00000302509.4
ENST00000571174.1
ENST00000576688.1
 UMOD






uromodulin






chr5_+_161494770 0.002 ENST00000414552.2
ENST00000361925.4
 GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 2.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0050653 UDP-N-acetylgalactosamine metabolic process(GO:0019276) chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.2 0.9 GO:0008907 integrase activity(GO:0008907)
0.1 0.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0047042 androsterone dehydrogenase (B-specific) activity(GO:0047042) indanol dehydrogenase activity(GO:0047718)
0.1 0.3 GO:0047115 androsterone dehydrogenase activity(GO:0047023) androsterone dehydrogenase (A-specific) activity(GO:0047026) trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)