Motif ID: SP1

Z-value: 2.891


Transcription factors associated with SP1:

Gene SymbolEntrez IDGene Name
SP1 ENSG00000185591.5 SP1



Activity profile for motif SP1.

activity profile for motif SP1


Sorted Z-values histogram for motif SP1

Sorted Z-values for motif SP1



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_149688655 6.649 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2




profilin 2




chr19_-_50143452 6.582 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr9_-_35691017 5.995 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr10_-_126849588 5.800 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr2_+_30369859 5.748 ENST00000402003.3
YPEL5
yippee-like 5 (Drosophila)
chr17_-_1619535 5.719 ENST00000573075.1
ENST00000574306.1
MIR22HG

MIR22 host gene (non-protein coding)

chr19_+_41725088 5.574 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr17_-_1619491 5.379 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22HG














MIR22 host gene (non-protein coding)














chr2_+_30369807 5.043 ENST00000379520.3
ENST00000379519.3
ENST00000261353.4
YPEL5


yippee-like 5 (Drosophila)


chr3_-_149688502 5.000 ENST00000481767.1
ENST00000475518.1
PFN2

profilin 2

chr5_+_52776228 4.571 ENST00000256759.3
FST
follistatin
chr3_+_135684515 4.563 ENST00000264977.3
ENST00000490467.1
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr4_-_157892498 4.520 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr2_-_161350305 4.308 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_-_225840747 4.303 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chrX_-_34675391 4.184 ENST00000275954.3
TMEM47
transmembrane protein 47
chr2_-_224903995 4.161 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
SERPINE2


serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2


chrX_-_106243451 4.106 ENST00000355610.4
ENST00000535534.1
MORC4

MORC family CW-type zinc finger 4

chr11_-_2160180 4.078 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_+_65686802 4.070 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr7_+_130131907 4.051 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chrX_+_54834791 4.029 ENST00000218439.4
ENST00000375058.1
ENST00000375060.1
MAGED2


melanoma antigen family D, 2


chr4_-_57976544 3.973 ENST00000295666.4
ENST00000537922.1
IGFBP7

insulin-like growth factor binding protein 7

chr2_+_241375069 3.972 ENST00000264039.2
GPC1
glypican 1
chr13_-_110438914 3.969 ENST00000375856.3
IRS2
insulin receptor substrate 2
chr8_+_26371763 3.955 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr5_-_16936340 3.946 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr2_+_235860616 3.906 ENST00000392011.2
SH3BP4
SH3-domain binding protein 4
chr3_-_32022733 3.894 ENST00000438237.2
ENST00000396556.2
OSBPL10

oxysterol binding protein-like 10

chrX_+_135229559 3.886 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr2_-_110371720 3.872 ENST00000356688.4
SEPT10
septin 10
chr11_+_65686952 3.842 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr20_-_17662705 3.837 ENST00000455029.2
RRBP1
ribosome binding protein 1
chrX_+_135229600 3.830 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr5_+_52776449 3.796 ENST00000396947.3
FST
follistatin
chr1_+_114522049 3.779 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr3_+_110790590 3.653 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr11_-_115375107 3.649 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr12_+_49212514 3.640 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3


calcium channel, voltage-dependent, beta 3 subunit


chr12_-_106641728 3.636 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr14_-_69446034 3.624 ENST00000193403.6
ACTN1
actinin, alpha 1
chr4_-_177713788 3.610 ENST00000280193.2
VEGFC
vascular endothelial growth factor C
chr1_-_68299130 3.597 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr17_-_3571934 3.594 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr6_+_83073952 3.565 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr18_+_3449821 3.554 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr20_+_56884752 3.474 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr3_-_149688896 3.438 ENST00000239940.7
PFN2
profilin 2
chr7_+_17338239 3.420 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr2_-_161349909 3.416 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_-_20812690 3.402 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_+_36582857 3.397 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr16_-_65155979 3.393 ENST00000562325.1
ENST00000268603.4
CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

chr17_-_66453562 3.374 ENST00000262139.5
ENST00000546360.1
WIPI1

WD repeat domain, phosphoinositide interacting 1

chr10_+_114709999 3.363 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2






transcription factor 7-like 2 (T-cell specific, HMG-box)






chr6_-_167040731 3.347 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr11_-_111783595 3.333 ENST00000528628.1
CRYAB
crystallin, alpha B
chr14_-_69445968 3.315 ENST00000438964.2
ACTN1
actinin, alpha 1
chr6_-_128841503 3.301 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr9_+_133320301 3.292 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr2_+_46926326 3.286 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_+_12696102 3.263 ENST00000527636.1
ENST00000527376.1
TEAD1

TEA domain family member 1 (SV40 transcriptional enhancer factor)

chr17_+_48133459 3.252 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr8_-_67525473 3.239 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr20_-_17662878 3.205 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr3_-_124606074 3.195 ENST00000296181.4
ITGB5
integrin, beta 5
chr22_+_33197683 3.187 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_227664474 3.186 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr2_+_5832799 3.169 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr2_+_173292390 3.126 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr9_+_36036430 3.112 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr2_+_24272543 3.111 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr11_+_65686728 3.109 ENST00000312515.2
ENST00000525501.1
DRAP1

DR1-associated protein 1 (negative cofactor 2 alpha)

chr7_+_65670186 3.101 ENST00000304842.5
ENST00000442120.1
TPST1

tyrosylprotein sulfotransferase 1

chr2_-_235405679 3.075 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chrX_+_135229731 3.036 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr9_+_133320339 3.031 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
ASS1


argininosuccinate synthase 1


chr2_+_173292301 3.013 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chrX_-_128657457 3.013 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


chr19_+_54694119 2.998 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34


TSEN34 tRNA splicing endonuclease subunit


chr18_+_3449695 2.948 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chrX_+_54835493 2.930 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr3_-_45267760 2.921 ENST00000503771.1
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr12_+_6309517 2.899 ENST00000382519.4
ENST00000009180.4
CD9

CD9 molecule

chr10_+_13142075 2.883 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN



optineurin



chr3_-_120170052 2.865 ENST00000295633.3
FSTL1
follistatin-like 1
chr3_-_114866084 2.859 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_102268484 2.858 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_65686496 2.853 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr9_-_35689900 2.836 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
TPM2


tropomyosin 2 (beta)


chr14_-_69445793 2.797 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr4_+_88928777 2.774 ENST00000237596.2
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr10_-_81205373 2.773 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr2_-_110371664 2.773 ENST00000545389.1
ENST00000423520.1
SEPT10

septin 10

chr2_-_158732340 2.763 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1



activin A receptor, type I



chr6_-_33285505 2.753 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr8_+_38854418 2.753 ENST00000481513.1
ENST00000487273.2
ADAM9

ADAM metallopeptidase domain 9

chr2_+_173292280 2.746 ENST00000264107.7
ITGA6
integrin, alpha 6
chr8_+_94929168 2.741 ENST00000518107.1
ENST00000396200.3
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr21_+_42539701 2.727 ENST00000330333.6
ENST00000328735.6
ENST00000347667.5
BACE2


beta-site APP-cleaving enzyme 2


chr4_-_102268628 2.727 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr4_+_169753156 2.712 ENST00000393726.3
ENST00000507735.1
PALLD

palladin, cytoskeletal associated protein

chr1_+_169075554 2.710 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_-_42277203 2.705 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr13_+_73632897 2.694 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr14_-_30396802 2.669 ENST00000415220.2
PRKD1
protein kinase D1
chr2_+_20646824 2.667 ENST00000272233.4
RHOB
ras homolog family member B
chr3_-_52002403 2.663 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4



poly(rC) binding protein 4



chr15_-_59041768 2.648 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM10



ADAM metallopeptidase domain 10



chr16_-_65155833 2.646 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11


cadherin 11, type 2, OB-cadherin (osteoblast)


chr11_+_69455855 2.640 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr14_+_21538429 2.639 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chr4_-_39529049 2.638 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UGDH


UDP-glucose 6-dehydrogenase


chr14_-_53417732 2.627 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2



chr4_-_39529180 2.626 ENST00000515021.1
ENST00000510490.1
ENST00000316423.6
UGDH


UDP-glucose 6-dehydrogenase


chr2_+_24272576 2.619 ENST00000380986.4
ENST00000452109.1
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr8_+_94929110 2.618 ENST00000520728.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_-_216300784 2.618 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr17_-_1389228 2.616 ENST00000438665.2
MYO1C
myosin IC
chr16_+_56691838 2.612 ENST00000394501.2
MT1F
metallothionein 1F
chr9_+_131314859 2.611 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
SPTAN1


spectrin, alpha, non-erythrocytic 1


chr11_+_12695944 2.594 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_-_110371777 2.581 ENST00000397712.2
SEPT10
septin 10
chr8_+_94929077 2.575 ENST00000297598.4
ENST00000520614.1
PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr21_+_35014783 2.550 ENST00000381291.4
ENST00000381285.4
ENST00000399367.3
ENST00000399352.1
ENST00000399355.2
ENST00000399349.1
ITSN1





intersectin 1 (SH3 domain protein)





chr9_-_35115836 2.527 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
FAM214B


family with sequence similarity 214, member B


chr4_+_38869410 2.520 ENST00000358869.2
FAM114A1
family with sequence similarity 114, member A1
chr2_+_187454749 2.518 ENST00000261023.3
ENST00000374907.3
ITGAV

integrin, alpha V

chr10_-_17659357 2.500 ENST00000326961.6
ENST00000361271.3
PTPLA

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A

chr11_+_117070037 2.499 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chrX_-_51812268 2.498 ENST00000486010.1
ENST00000497164.1
ENST00000360134.6
ENST00000485287.1
ENST00000335504.5
ENST00000431659.1
MAGED4B





melanoma antigen family D, 4B





chr10_-_126849068 2.488 ENST00000494626.2
ENST00000337195.5
CTBP2

C-terminal binding protein 2

chr21_-_28217721 2.483 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr21_-_28338732 2.476 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr10_+_13142225 2.475 ENST00000378747.3
OPTN
optineurin
chr4_+_6271558 2.465 ENST00000503569.1
ENST00000226760.1
WFS1

Wolfram syndrome 1 (wolframin)

chrX_-_37706815 2.451 ENST00000378578.4
DYNLT3
dynein, light chain, Tctex-type 3
chr8_-_62627057 2.445 ENST00000519234.1
ENST00000379449.6
ENST00000379454.4
ENST00000518068.1
ENST00000517856.1
ENST00000356457.5
ASPH





aspartate beta-hydroxylase





chr2_+_242255297 2.441 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2









septin 2









chr5_-_57756087 2.433 ENST00000274289.3
PLK2
polo-like kinase 2
chr2_+_46524537 2.428 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr3_+_105085734 2.427 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr9_+_139873264 2.425 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr15_-_30114622 2.422 ENST00000495972.2
ENST00000346128.6
TJP1

tight junction protein 1

chr19_-_36523709 2.422 ENST00000592017.1
ENST00000360535.4
CLIP3

CAP-GLY domain containing linker protein 3

chr5_+_135364584 2.399 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr16_+_3068393 2.385 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chrX_-_140271249 2.379 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr3_-_48130707 2.373 ENST00000360240.6
ENST00000383737.4
MAP4

microtubule-associated protein 4

chr22_+_38142235 2.350 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIOBP


TRIO and F-actin binding protein


chr12_+_110718921 2.345 ENST00000308664.6
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr17_-_48943706 2.344 ENST00000499247.2
TOB1
transducer of ERBB2, 1
chr18_+_33877654 2.339 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3



formin homology 2 domain containing 3



chr11_-_65686586 2.337 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr2_-_37899323 2.336 ENST00000295324.3
ENST00000457889.1
CDC42EP3

CDC42 effector protein (Rho GTPase binding) 3

chr2_-_56150910 2.334 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1








EGF containing fibulin-like extracellular matrix protein 1








chr16_+_56691911 2.327 ENST00000568475.1
MT1F
metallothionein 1F
chr15_+_63340647 2.323 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chr10_+_76586348 2.320 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr22_-_50746027 2.314 ENST00000425954.1
ENST00000449103.1
PLXNB2

plexin B2

chr7_-_19157248 2.305 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr10_+_124221036 2.295 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr17_+_60704762 2.290 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr22_+_38071615 2.290 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr5_-_172756506 2.283 ENST00000265087.4
STC2
stanniocalcin 2
chr14_+_21538517 2.276 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr7_+_94023873 2.276 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr11_-_12030629 2.274 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr6_-_110500905 2.273 ENST00000392587.2
WASF1
WAS protein family, member 1
chr5_+_148521381 2.242 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr2_+_62933001 2.238 ENST00000263991.5
ENST00000354487.3
EHBP1

EH domain binding protein 1

chr8_+_26435359 2.236 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr4_-_99579733 2.232 ENST00000305798.3
TSPAN5
tetraspanin 5
chr3_+_49507559 2.218 ENST00000421560.1
ENST00000308775.2
ENST00000545947.1
ENST00000541308.1
ENST00000539901.1
ENST00000538711.1
ENST00000418588.1
DAG1






dystroglycan 1 (dystrophin-associated glycoprotein 1)






chr22_+_31477296 2.211 ENST00000426927.1
ENST00000440425.1
ENST00000358743.1
ENST00000347557.2
ENST00000333137.7
SMTN




smoothelin




chr20_-_43977055 2.211 ENST00000372733.3
ENST00000537976.1
SDC4

syndecan 4

chr2_-_161264385 2.207 ENST00000409972.1
RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_78009647 2.194 ENST00000310924.2
TBC1D16
TBC1 domain family, member 16
chr7_+_79764104 2.192 ENST00000351004.3
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr5_-_176924562 2.183 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7






PDZ and LIM domain 7 (enigma)






chr1_+_211432775 2.180 ENST00000419091.2
RCOR3
REST corepressor 3
chr3_-_123603137 2.171 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr17_-_7307358 2.150 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr5_+_40679584 2.150 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr1_-_52456352 2.146 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr11_-_111783919 2.139 ENST00000531198.1
ENST00000533879.1
CRYAB

crystallin, alpha B

chr22_-_36784035 2.121 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr11_+_832804 2.118 ENST00000397420.3
ENST00000525718.1
CD151

CD151 molecule (Raph blood group)

chr5_+_82767487 2.117 ENST00000343200.5
ENST00000342785.4
VCAN

versican

chr19_+_41284121 2.108 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B


RAB4B, member RAS oncogene family


chr11_+_129939811 2.106 ENST00000345598.5
ENST00000338167.5
APLP2

amyloid beta (A4) precursor-like protein 2

chr7_+_100770328 2.099 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr8_+_26240414 2.099 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_+_160175201 2.096 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr1_-_151965048 2.094 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr19_+_8478154 2.092 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2






membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase






chrX_-_51239425 2.091 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr11_-_65640198 2.090 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr7_+_116165038 2.090 ENST00000393470.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr14_-_74960030 2.087 ENST00000553490.1
ENST00000557510.1
NPC2

Niemann-Pick disease, type C2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
2.0 6.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
2.0 12.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
1.9 5.8 GO:0060539 diaphragm development(GO:0060539)
1.9 5.6 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
1.9 5.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.7 6.9 GO:0090161 Golgi ribbon formation(GO:0090161)
1.6 4.7 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
1.5 7.3 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
1.4 5.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
1.4 11.3 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
1.4 5.6 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
1.3 1.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
1.3 7.6 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
1.2 1.2 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
1.2 4.7 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
1.2 3.5 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
1.1 3.4 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.1 3.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
1.1 4.3 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
1.1 3.2 GO:0048627 myoblast development(GO:0048627)
1.0 6.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
1.0 2.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
1.0 4.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
1.0 3.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
1.0 2.9 GO:2000064 regulation of cortisol biosynthetic process(GO:2000064)
1.0 1.9 GO:0046836 glycolipid transport(GO:0046836)
1.0 5.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.0 4.8 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
1.0 3.8 GO:0030913 paranodal junction assembly(GO:0030913)
0.9 4.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.9 0.9 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.9 2.7 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.9 2.7 GO:0051541 elastin metabolic process(GO:0051541)
0.9 2.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.9 5.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.9 2.6 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.8 2.5 GO:0008218 bioluminescence(GO:0008218)
0.8 2.5 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.8 1.6 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.8 2.5 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.8 2.5 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.8 2.4 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.8 3.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.8 22.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.8 3.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.8 6.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.8 5.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.8 2.3 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of mesoderm development(GO:2000380)
0.8 7.6 GO:0031017 exocrine pancreas development(GO:0031017)
0.7 0.7 GO:0010470 regulation of gastrulation(GO:0010470)
0.7 2.2 GO:0002575 basophil chemotaxis(GO:0002575)
0.7 11.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.7 0.7 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.7 3.5 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.7 2.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.7 4.1 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.7 1.3 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.7 9.3 GO:0000052 citrulline metabolic process(GO:0000052)
0.6 0.6 GO:0070669 response to interleukin-2(GO:0070669)
0.6 1.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.6 3.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.6 0.6 GO:0007412 axon target recognition(GO:0007412)
0.6 3.0 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.6 5.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.6 1.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.6 2.4 GO:2001258 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315) negative regulation of calcium ion transmembrane transporter activity(GO:1901020) negative regulation of cation channel activity(GO:2001258)
0.6 2.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.6 1.8 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.6 1.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.6 0.6 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.6 1.7 GO:0071476 response to vitamin B1(GO:0010266) cellular hypotonic response(GO:0071476)
0.6 1.7 GO:0060596 mammary placode formation(GO:0060596)
0.6 2.8 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.6 10.1 GO:0035329 hippo signaling(GO:0035329)
0.6 2.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.6 1.7 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.6 2.8 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.6 3.3 GO:0016264 gap junction assembly(GO:0016264)
0.6 1.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.6 3.9 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.5 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 4.9 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.5 1.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.5 1.6 GO:0070672 response to interleukin-15(GO:0070672)
0.5 0.5 GO:0014044 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.5 2.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.5 3.6 GO:0034465 cellular potassium ion homeostasis(GO:0030007) response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.5 0.5 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.5 1.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.5 4.0 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.5 1.5 GO:0001955 blood vessel maturation(GO:0001955)
0.5 3.4 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.5 1.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.5 1.5 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.5 1.9 GO:0060209 estrus(GO:0060209)
0.5 4.2 GO:0001967 suckling behavior(GO:0001967)
0.5 2.4 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.5 0.9 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.5 6.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.5 2.8 GO:0070141 response to UV-A(GO:0070141)
0.5 0.5 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.5 1.4 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.5 1.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.5 0.9 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.5 0.5 GO:0060976 coronary vasculature development(GO:0060976)
0.5 2.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.4 2.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.4 1.8 GO:0071071 regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071)
0.4 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.4 1.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 2.6 GO:0018345 protein palmitoylation(GO:0018345)
0.4 1.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 3.5 GO:0006013 mannose metabolic process(GO:0006013)
0.4 1.3 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.4 3.9 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4 1.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.4 0.4 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.4 1.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.4 1.7 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.4 7.0 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.4 2.5 GO:0008354 germ cell migration(GO:0008354)
0.4 0.8 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.4 1.6 GO:0033986 response to methanol(GO:0033986) response to chromate(GO:0046687)
0.4 2.0 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.4 3.7 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.4 2.8 GO:0022417 protein maturation by protein folding(GO:0022417)
0.4 1.2 GO:0006740 NADPH regeneration(GO:0006740)
0.4 0.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.4 2.0 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.4 0.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.4 0.4 GO:0010044 response to aluminum ion(GO:0010044)
0.4 1.9 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.4 0.8 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.4 0.4 GO:0050951 sensory perception of temperature stimulus(GO:0050951)
0.4 1.1 GO:0030035 microspike assembly(GO:0030035)
0.4 0.8 GO:0022038 corpus callosum development(GO:0022038)
0.4 1.1 GO:0007538 primary sex determination(GO:0007538)
0.4 1.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 0.7 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) demethylation(GO:0070988)
0.4 1.5 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.4 2.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.4 0.4 GO:0070527 platelet aggregation(GO:0070527)
0.4 2.2 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.4 1.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.4 1.5 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.4 3.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.4 3.6 GO:0051014 actin filament severing(GO:0051014)
0.4 1.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.4 1.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.4 4.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.4 3.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 3.2 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.4 1.4 GO:0001941 postsynaptic membrane organization(GO:0001941)
0.3 0.3 GO:0048771 tissue remodeling(GO:0048771)
0.3 1.7 GO:0090343 positive regulation of cell aging(GO:0090343)
0.3 0.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307) DNA dealkylation(GO:0035510)
0.3 2.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.3 1.7 GO:1903008 organelle disassembly(GO:1903008)
0.3 1.7 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.3 0.7 GO:0070884 calcineurin-NFAT signaling cascade(GO:0033173) regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.3 33.8 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.3 22.7 GO:0034332 adherens junction organization(GO:0034332)
0.3 2.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.3 3.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.3 6.5 GO:0007032 endosome organization(GO:0007032)
0.3 1.0 GO:0032571 response to vitamin K(GO:0032571)
0.3 1.0 GO:0071529 cementum mineralization(GO:0071529)
0.3 1.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 0.9 GO:0031133 regulation of axon diameter(GO:0031133) regulation of cell projection size(GO:0032536)
0.3 5.0 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.3 1.3 GO:0030240 skeletal myofibril assembly(GO:0014866) skeletal muscle thin filament assembly(GO:0030240)
0.3 3.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.3 0.3 GO:0003338 metanephros morphogenesis(GO:0003338)
0.3 1.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 2.5 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.3 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.3 0.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.3 0.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.3 0.9 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 1.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 0.9 GO:0060129 corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.3 0.6 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.3 1.2 GO:0019046 release from viral latency(GO:0019046)
0.3 0.3 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.3 2.0 GO:0060414 aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.3 0.6 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.3 0.6 GO:0021570 rhombomere 4 development(GO:0021570)
0.3 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.3 3.8 GO:0008347 glial cell migration(GO:0008347)
0.3 1.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.1 GO:0002331 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.3 0.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.3 0.5 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.3 1.8 GO:0015904 tetracycline transport(GO:0015904)
0.3 0.8 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.3 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.3 1.0 GO:0009301 snRNA transcription(GO:0009301)
0.3 3.8 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.3 2.3 GO:0046697 decidualization(GO:0046697)
0.3 0.8 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3 0.5 GO:0071479 cellular response to radiation(GO:0071478) cellular response to ionizing radiation(GO:0071479)
0.2 0.7 GO:0030517 negative regulation of axon extension(GO:0030517)
0.2 0.7 GO:0003197 endocardial cushion development(GO:0003197)
0.2 0.7 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 3.6 GO:0032456 endocytic recycling(GO:0032456)
0.2 1.2 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.2 0.5 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.2 1.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.2 0.7 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.2 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 1.6 GO:0031529 ruffle organization(GO:0031529)
0.2 1.6 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 5.7 GO:0043462 regulation of ATPase activity(GO:0043462)
0.2 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.2 0.4 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.2 2.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 3.6 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.2 0.4 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.2 0.7 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.2 0.2 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.2 1.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.3 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.2 5.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 1.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.2 1.1 GO:1903020 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.2 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.3 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.2 1.3 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.2 0.6 GO:0043276 anoikis(GO:0043276)
0.2 0.8 GO:0015825 L-serine transport(GO:0015825)
0.2 1.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 1.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 2.3 GO:0007141 male meiosis I(GO:0007141)
0.2 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.2 0.6 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.2 0.8 GO:0021854 hypothalamus development(GO:0021854)
0.2 0.8 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.2 1.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 1.4 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.2 0.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.2 0.2 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.2 1.2 GO:0045916 negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.2 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.2 3.0 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.2 3.9 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.2 0.2 GO:0001885 endothelial cell development(GO:0001885)
0.2 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.2 1.7 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 1.3 GO:0097576 vacuole fusion(GO:0097576)
0.2 2.8 GO:0098764 meiosis I cell cycle phase(GO:0098764)
0.2 0.4 GO:0050957 equilibrioception(GO:0050957)
0.2 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.2 0.9 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 0.9 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.2 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 1.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.2 0.5 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.2 0.4 GO:0016241 regulation of macroautophagy(GO:0016241)
0.2 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 0.9 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.5 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.4 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.2 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.2 1.4 GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.2 0.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 0.5 GO:0014047 glutamate secretion(GO:0014047)
0.2 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 0.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.2 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.8 GO:0021548 pons development(GO:0021548)
0.2 2.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.2 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.2 1.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.2 0.2 GO:0045926 negative regulation of growth(GO:0045926)
0.2 0.7 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.2 1.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.7 GO:0042693 muscle cell fate commitment(GO:0042693)
0.2 0.5 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.2 1.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.6 GO:0019321 pentose metabolic process(GO:0019321)
0.2 1.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.2 0.2 GO:0060343 trabecula formation(GO:0060343) trabecula morphogenesis(GO:0061383)
0.2 0.8 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.2 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.7 GO:0002347 response to tumor cell(GO:0002347)
0.2 0.6 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 2.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.2 2.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2 1.1 GO:0016559 peroxisome fission(GO:0016559)
0.2 0.5 GO:0010761 fibroblast migration(GO:0010761)
0.2 0.5 GO:0045062 extrathymic T cell differentiation(GO:0033078) extrathymic T cell selection(GO:0045062)
0.2 0.3 GO:0006907 pinocytosis(GO:0006907)
0.2 3.1 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.6 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 0.5 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.3 GO:0046931 pore complex assembly(GO:0046931)
0.2 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.2 0.3 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.2 0.6 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.2 1.8 GO:0032964 collagen biosynthetic process(GO:0032964)
0.2 3.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.2 1.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 0.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 1.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.6 GO:0042335 cuticle development(GO:0042335)
0.1 0.1 GO:0006679 glucosylceramide metabolic process(GO:0006678) glucosylceramide biosynthetic process(GO:0006679)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.7 GO:0015827 tryptophan transport(GO:0015827) leucine import(GO:0060356)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0060405 regulation of penile erection(GO:0060405)
0.1 0.9 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 2.7 GO:0016236 macroautophagy(GO:0016236)
0.1 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 0.3 GO:0030856 regulation of epithelial cell differentiation(GO:0030856)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 27.8 GO:0007517 muscle organ development(GO:0007517)
0.1 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.7 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.6 GO:0032288 myelin assembly(GO:0032288)
0.1 1.8 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.1 1.0 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 1.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 1.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 1.3 GO:0007567 parturition(GO:0007567)
0.1 0.7 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.5 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.4 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.4 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.8 GO:0001945 lymph vessel development(GO:0001945)
0.1 3.4 GO:0032963 collagen metabolic process(GO:0032963)
0.1 0.8 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 0.9 GO:0043113 receptor clustering(GO:0043113)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.1 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 3.8 GO:0007613 memory(GO:0007613)
0.1 2.0 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.1 3.5 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.1 0.1 GO:0043270 positive regulation of ion transport(GO:0043270)
0.1 2.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.7 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 2.4 GO:0018208 peptidyl-proline modification(GO:0018208)
0.1 3.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 8.5 GO:0009408 response to heat(GO:0009408)
0.1 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.6 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.1 9.8 GO:0002576 platelet degranulation(GO:0002576)
0.1 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 1.5 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.8 GO:0045116 protein neddylation(GO:0045116)
0.1 0.2 GO:0034341 response to interferon-gamma(GO:0034341)
0.1 0.7 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 0.6 GO:0032909 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1 0.6 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 1.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.2 GO:0030317 sperm motility(GO:0030317)
0.1 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.1 0.4 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 2.6 GO:0007033 vacuole organization(GO:0007033)
0.1 0.2 GO:0090042 tubulin deacetylation(GO:0090042)
0.1 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.1 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.1 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.9 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 0.9 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.3 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.9 GO:0048678 response to axon injury(GO:0048678)
0.1 0.7 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.1 3.9 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 0.4 GO:0006694 steroid biosynthetic process(GO:0006694)
0.1 0.3 GO:0021924 cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.1 0.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.8 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.1 0.2 GO:0046060 dATP metabolic process(GO:0046060)
0.1 3.7 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.3 GO:1902414 positive regulation of receptor recycling(GO:0001921) protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.1 0.1 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.1 0.4 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1 2.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.1 0.3 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.4 GO:0071260 cellular response to abiotic stimulus(GO:0071214) cellular response to mechanical stimulus(GO:0071260)
0.1 0.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting two-sector ATPase complex assembly(GO:0070071) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 2.3 GO:0051899 membrane depolarization(GO:0051899)
0.1 0.5 GO:0050974 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910) detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.1 1.2 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.3 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.6 GO:0007566 embryo implantation(GO:0007566)
0.1 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.9 GO:0042246 tissue regeneration(GO:0042246)
0.1 1.1 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.1 1.3 GO:0009584 detection of visible light(GO:0009584)
0.1 2.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 2.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 0.2 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.4 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.6 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.1 0.6 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.1 0.9 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.1 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.3 GO:0003407 neural retina development(GO:0003407)
0.1 0.2 GO:0071901 negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.1 0.2 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.1 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 0.9 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.6 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.1 0.1 GO:0048562 embryonic organ morphogenesis(GO:0048562)
0.1 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.1 GO:0032847 regulation of cellular pH reduction(GO:0032847)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 3.2 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 0.8 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 1.9 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.2 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 2.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 0.7 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 3.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.9 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.1 20.5 GO:0097485 axon guidance(GO:0007411) neuron projection guidance(GO:0097485)
0.1 0.1 GO:0060073 micturition(GO:0060073)
0.1 0.4 GO:0000090 mitotic anaphase(GO:0000090)
0.1 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 0.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.2 GO:0007498 mesoderm development(GO:0007498)
0.1 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.1 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.1 0.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 0.4 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 0.1 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) striated muscle adaptation(GO:0014888) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.1 0.5 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.1 0.6 GO:0001709 cell fate determination(GO:0001709)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.5 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.1 0.2 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 2.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.1 1.5 GO:0034329 cell junction assembly(GO:0034329)
0.1 0.6 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 0.1 GO:0032106 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.1 0.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.4 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.1 0.3 GO:0014037 Schwann cell differentiation(GO:0014037)
0.1 0.3 GO:0006029 proteoglycan metabolic process(GO:0006029)
0.1 0.2 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.2 GO:0071801 podosome assembly(GO:0071800) regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 0.2 GO:0018126 protein hydroxylation(GO:0018126)
0.1 0.3 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.1 GO:2000021 regulation of ion homeostasis(GO:2000021)
0.1 0.3 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 2.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.5 GO:0045576 mast cell activation(GO:0045576)
0.1 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.1 5.8 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.9 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.3 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.0 1.5 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 1.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.9 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0007548 sex differentiation(GO:0007548)
0.0 0.1 GO:0042727 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 1.7 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0010759 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 4.7 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0070244 negative regulation of T cell apoptotic process(GO:0070233) negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.8 GO:0048477 oogenesis(GO:0048477)
0.0 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.9 GO:0006501 C-terminal protein lipidation(GO:0006501) preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.8 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.0 GO:0098762 meiotic cell cycle phase(GO:0098762)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.3 GO:0048536 spleen development(GO:0048536)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0007435 salivary gland morphogenesis(GO:0007435)
0.0 0.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0051271 negative regulation of cellular component movement(GO:0051271)
0.0 1.8 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 1.3 GO:0007338 single fertilization(GO:0007338)
0.0 0.2 GO:2001022 positive regulation of DNA repair(GO:0045739) positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.1 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.1 GO:0007584 response to nutrient(GO:0007584)
0.0 0.1 GO:0007285 primary spermatocyte growth(GO:0007285)
0.0 0.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 1.2 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.7 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 1.2 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.1 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.3 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.8 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0015758 hexose transport(GO:0008645) monosaccharide transport(GO:0015749) glucose transport(GO:0015758)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.6 GO:0042157 lipoprotein metabolic process(GO:0042157)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0042267 natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.8 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0001974 blood vessel remodeling(GO:0001974)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.0 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104) uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 1.4 GO:0030029 actin filament-based process(GO:0030029)
0.0 0.0 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0048483 autonomic nervous system development(GO:0048483)
0.0 0.7 GO:0031589 cell-substrate adhesion(GO:0031589)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) regulation of protein folding(GO:1903332) negative regulation of protein folding(GO:1903333)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.5 GO:0006897 endocytosis(GO:0006897)
0.0 0.2 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.8 GO:0071559 response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0045927 positive regulation of growth(GO:0045927)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.0 GO:0034765 regulation of transmembrane transport(GO:0034762) regulation of ion transmembrane transport(GO:0034765)
0.0 0.0 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.5 GO:0007588 excretion(GO:0007588)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.0 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.2 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0005955 calcineurin complex(GO:0005955)
1.4 4.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772)
1.3 6.5 GO:0060171 stereocilium membrane(GO:0060171)
1.2 23.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
1.2 4.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.1 6.5 GO:0070852 cell body fiber(GO:0070852)
1.1 4.3 GO:0043259 laminin-10 complex(GO:0043259)
1.0 6.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.9 4.6 GO:0070938 contractile ring(GO:0070938)
0.8 7.2 GO:0000145 exocyst(GO:0000145)
0.8 3.9 GO:0032449 CBM complex(GO:0032449)
0.8 3.1 GO:0070695 FHF complex(GO:0070695)
0.7 3.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.7 9.3 GO:0031143 pseudopodium(GO:0031143)
0.7 5.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.7 3.3 GO:0005899 insulin receptor complex(GO:0005899)
0.6 8.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 1.8 GO:0071953 elastic fiber(GO:0071953)
0.6 1.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.6 9.4 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.5 1.6 GO:0005588 collagen type V trimer(GO:0005588)
0.5 3.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.5 1.9 GO:0043219 lateral loop(GO:0043219)
0.5 5.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.5 2.8 GO:0031512 motile primary cilium(GO:0031512)
0.5 3.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.5 20.8 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.4 1.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.4 4.6 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.6 GO:0071797 LUBAC complex(GO:0071797)
0.4 2.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 1.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.4 1.1 GO:0032420 stereocilium(GO:0032420)
0.4 17.5 GO:0042641 actomyosin(GO:0042641)
0.3 5.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 3.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3 3.0 GO:0034464 BBSome(GO:0034464)
0.3 3.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 1.3 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 2.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.3 2.3 GO:0005915 zonula adherens(GO:0005915)
0.3 0.8 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 5.5 GO:0005581 collagen trimer(GO:0005581)
0.3 0.8 GO:0032432 actin filament bundle(GO:0032432)
0.3 8.4 GO:0005811 lipid particle(GO:0005811)
0.3 1.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.3 1.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.3 4.2 GO:0008091 spectrin(GO:0008091)
0.3 18.6 GO:0005604 basement membrane(GO:0005604)
0.3 1.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.3 2.0 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 2.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.2 3.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 0.9 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.2 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.2 1.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.9 GO:0000124 SAGA complex(GO:0000124)
0.2 3.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.1 GO:0030312 external encapsulating structure(GO:0030312)
0.2 1.3 GO:0005916 fascia adherens(GO:0005916)
0.2 4.9 GO:0005776 autophagosome(GO:0005776)
0.2 8.0 GO:0043195 terminal bouton(GO:0043195)
0.2 68.6 GO:0031012 extracellular matrix(GO:0031012)
0.2 6.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 2.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 4.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.2 1.9 GO:0043034 costamere(GO:0043034)
0.2 16.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.2 3.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 1.8 GO:0031094 platelet dense tubular network(GO:0031094)
0.2 1.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 0.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.6 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.2 0.7 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 6.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 1.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 15.0 GO:0005802 trans-Golgi network(GO:0005802)
0.2 9.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 0.5 GO:0001940 male pronucleus(GO:0001940)
0.2 4.4 GO:0030175 filopodium(GO:0030175)
0.2 2.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.2 9.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.2 1.2 GO:0070688 MLL5-L complex(GO:0070688)
0.2 6.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 8.2 GO:0031091 platelet alpha granule(GO:0031091)
0.1 2.4 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.9 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 2.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 1.7 GO:0005625 obsolete soluble fraction(GO:0005625)
0.1 10.3 GO:0042383 sarcolemma(GO:0042383)
0.1 2.8 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.4 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 12.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.4 GO:0030286 dynein complex(GO:0030286)
0.1 0.6 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.5 GO:0016528 sarcoplasm(GO:0016528)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 42.1 GO:0015629 actin cytoskeleton(GO:0015629)
0.1 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.1 8.2 GO:0030426 growth cone(GO:0030426)
0.1 8.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 2.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.9 GO:0031514 motile cilium(GO:0031514)
0.1 2.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.2 GO:0032059 bleb(GO:0032059)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.2 GO:0000800 lateral element(GO:0000800)
0.1 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.3 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.6 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.3 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.1 4.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 4.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.1 7.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.1 3.9 GO:0019717 obsolete synaptosome(GO:0019717)
0.1 1.6 GO:0016234 inclusion body(GO:0016234)
0.1 0.8 GO:0001772 immunological synapse(GO:0001772)
0.1 6.8 GO:0031252 cell leading edge(GO:0031252)
0.1 0.2 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.4 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 0.2 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 17.0 GO:0005774 vacuolar membrane(GO:0005774)
0.1 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 70.5 GO:0005576 extracellular region(GO:0005576)
0.0 3.7 GO:0043235 receptor complex(GO:0043235)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 8.8 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 3.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.3 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 1.0 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 15.5 GO:0044432 endoplasmic reticulum part(GO:0044432)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0044449 contractile fiber part(GO:0044449)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 9.6 GO:0071944 cell periphery(GO:0071944)
0.0 0.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0005624 obsolete membrane fraction(GO:0005624)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
1.8 9.2 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
1.7 8.5 GO:0016403 dimethylargininase activity(GO:0016403)
1.7 5.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
1.4 11.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.0 14.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.0 9.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.9 2.8 GO:0048184 obsolete follistatin binding(GO:0048184)
0.9 2.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.8 2.5 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.8 8.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.8 2.4 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.7 3.7 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.7 3.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.7 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.7 3.5 GO:0045499 chemorepellent activity(GO:0045499)
0.7 4.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.7 2.7 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542)
0.7 5.3 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.7 2.0 GO:0070052 collagen V binding(GO:0070052)
0.7 2.0 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.7 0.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.7 13.7 GO:0017166 vinculin binding(GO:0017166)
0.6 1.9 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.6 3.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.6 2.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.6 2.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.6 9.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 1.2 GO:0033691 sialic acid binding(GO:0033691)
0.6 4.2 GO:0042731 PH domain binding(GO:0042731)
0.6 1.8 GO:0031493 nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093)
0.6 5.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.6 2.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.6 15.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.6 3.4 GO:0048495 Roundabout binding(GO:0048495)
0.6 2.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.6 1.7 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.5 3.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.5 1.5 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.5 3.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.5 4.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.5 5.4 GO:0015643 toxic substance binding(GO:0015643)
0.5 1.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 2.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.5 6.5 GO:0046870 cadmium ion binding(GO:0046870)
0.5 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.5 3.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.4 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 4.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 1.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 2.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 13.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.4 2.6 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.4 1.3 GO:0030350 iron-responsive element binding(GO:0030350)
0.4 9.3 GO:0070064 proline-rich region binding(GO:0070064)
0.4 5.0 GO:0050780 dopamine receptor binding(GO:0050780)
0.4 1.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4 2.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.4 2.0 GO:0004064 arylesterase activity(GO:0004064)
0.4 2.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 34.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.4 0.4 GO:0070405 ammonium ion binding(GO:0070405)
0.4 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.4 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.4 1.9 GO:0034711 inhibin binding(GO:0034711)
0.4 0.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 1.5 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.4 3.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.4 2.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.4 1.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.4 2.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.4 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 7.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.4 1.5 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.4 2.6 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.4 2.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.4 2.5 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.4 5.4 GO:0043498 obsolete cell surface binding(GO:0043498)
0.4 1.1 GO:0008431 vitamin E binding(GO:0008431)
0.4 1.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 1.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.4 3.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.4 1.4 GO:0004359 glutaminase activity(GO:0004359)
0.3 1.7 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.3 1.0 GO:0000150 recombinase activity(GO:0000150)
0.3 4.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.0 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.3 2.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 7.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 1.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 6.6 GO:0051861 glycolipid binding(GO:0051861)
0.3 1.0 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.3 3.3 GO:0050811 GABA receptor binding(GO:0050811)
0.3 1.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 3.2 GO:0003785 actin monomer binding(GO:0003785)
0.3 1.6 GO:0005534 galactose binding(GO:0005534)
0.3 2.2 GO:0031491 nucleosome binding(GO:0031491)
0.3 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 1.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 2.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.3 6.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 1.9 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.3 8.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 5.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 3.1 GO:0042301 phosphate ion binding(GO:0042301)
0.3 0.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 1.8 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 1.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.3 1.5 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.3 1.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.3 1.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.7 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 2.6 GO:0005110 frizzled-2 binding(GO:0005110)
0.3 1.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 1.7 GO:0019863 IgE binding(GO:0019863)
0.3 0.8 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 4.6 GO:0005522 profilin binding(GO:0005522)
0.3 1.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.3 8.0 GO:0019003 GDP binding(GO:0019003)
0.3 1.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 1.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 0.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.3 26.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 0.8 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.3 7.7 GO:0015485 cholesterol binding(GO:0015485)
0.3 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 4.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 10.9 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.7 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.2 2.0 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 3.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 6.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 3.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.2 0.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 0.7 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.2 6.7 GO:0005518 collagen binding(GO:0005518)
0.2 1.4 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.2 0.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 1.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 2.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 0.7 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 15.9 GO:0005178 integrin binding(GO:0005178)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.6 GO:0043199 sulfate binding(GO:0043199)
0.2 0.9 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 0.6 GO:0047708 biotinidase activity(GO:0047708)
0.2 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 0.6 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 1.6 GO:0030371 translation repressor activity(GO:0030371)
0.2 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.8 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 2.4 GO:0019841 retinol binding(GO:0019841)
0.2 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.8 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.2 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.2 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.2 2.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.2 0.9 GO:0002162 dystroglycan binding(GO:0002162)
0.2 3.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.2 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.8 GO:0030172 troponin C binding(GO:0030172)
0.2 2.0 GO:0044548 S100 protein binding(GO:0044548)
0.2 12.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.2 2.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 0.8 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.2 0.3 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.2 3.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 0.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 3.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 2.3 GO:0017022 myosin binding(GO:0017022)
0.2 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 0.5 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.2 3.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 0.5 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 1.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 1.8 GO:0031013 troponin I binding(GO:0031013)
0.2 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.2 1.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 2.5 GO:0005521 lamin binding(GO:0005521)
0.2 0.5 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 3.1 GO:0008143 poly(A) binding(GO:0008143)
0.2 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 3.1 GO:0030553 cGMP binding(GO:0030553)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 2.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.7 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 8.7 GO:0051287 NAD binding(GO:0051287)
0.1 0.4 GO:0044325 ion channel binding(GO:0044325)
0.1 1.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.8 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.7 GO:0043621 protein self-association(GO:0043621)
0.1 1.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 3.9 GO:0001948 glycoprotein binding(GO:0001948)
0.1 0.4 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.8 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 48.0 GO:0003779 actin binding(GO:0003779)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.4 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.1 0.4 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.5 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 1.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 2.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 2.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 2.6 GO:0051117 ATPase binding(GO:0051117)
0.1 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 5.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106)
0.1 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.9 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.1 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.6 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.1 4.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 0.4 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 9.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.7 GO:0005536 glucose binding(GO:0005536)
0.1 5.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.3 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 3.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0042166 acetylcholine binding(GO:0042166)
0.1 0.3 GO:0004913 interleukin-4 receptor activity(GO:0004913)
0.1 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 4.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 0.5 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 1.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 4.1 GO:0046332 SMAD binding(GO:0046332)
0.1 0.4 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.2 GO:0031711 angiotensin type I receptor activity(GO:0001596) acetyltransferase activator activity(GO:0010698) bradykinin receptor binding(GO:0031711)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 6.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.7 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 2.2 GO:0022843 voltage-gated cation channel activity(GO:0022843)
0.1 1.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 1.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.3 GO:0015923 mannosidase activity(GO:0015923)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.3 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.3 GO:0017096 acetylserotonin O-methyltransferase activity(GO:0017096)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 1.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 2.7 GO:0005496 steroid binding(GO:0005496)
0.1 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.8 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.1 0.2 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.1 0.2 GO:0035198 miRNA binding(GO:0035198)
0.1 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.1 0.3 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.9 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.3 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.2 GO:0034452 dynactin binding(GO:0034452)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 1.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.6 GO:0019838 growth factor binding(GO:0019838)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.3 GO:0005507 copper ion binding(GO:0005507)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 7.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 22.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0017108 crossover junction endodeoxyribonuclease activity(GO:0008821) 5'-flap endonuclease activity(GO:0017108)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.4 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 4.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.4 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 7.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.3 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.5 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.5 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0016297 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 0.1 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 5.4 GO:0019001 guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.0 0.0 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.4 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.0 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 1.8 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.0 GO:0016409 palmitoyltransferase activity(GO:0016409)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 23.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.3 37.7 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.3 9.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.3 8.2 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.3 0.3 ST_STAT3_PATHWAY STAT3 Pathway
0.2 1.7 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.2 5.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 2.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 0.4 ST_GAQ_PATHWAY G alpha q Pathway
0.1 1.2 ST_ADRENERGIC Adrenergic Pathway
0.1 1.1 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.7 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.1 SIG_CHEMOTAXIS Genes related to chemotaxis