Motif ID: SP100
Z-value: 1.696
Transcription factors associated with SP100:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| SP100 | ENSG00000067066.12 | SP100 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.8 | 5.7 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.5 | 2.0 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
| 0.4 | 1.1 | GO:0018243 | protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243) |
| 0.4 | 1.1 | GO:0003350 | pulmonary myocardium development(GO:0003350) |
| 0.4 | 2.2 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.4 | 5.1 | GO:1901797 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797) |
| 0.4 | 2.5 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.4 | 1.1 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
| 0.3 | 1.0 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
| 0.3 | 0.9 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.3 | 1.2 | GO:2000008 | regulation of protein localization to cell surface(GO:2000008) |
| 0.2 | 1.2 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) |
| 0.2 | 0.7 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.2 | 0.6 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.2 | 1.4 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 0.2 | 0.4 | GO:0071679 | commissural neuron axon guidance(GO:0071679) |
| 0.2 | 0.7 | GO:0019046 | release from viral latency(GO:0019046) |
| 0.2 | 1.0 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
| 0.2 | 1.1 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 0.2 | 0.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 1.0 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.1 | 1.1 | GO:0045003 | DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
| 0.1 | 0.4 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.1 | 1.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 0.1 | 1.0 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.1 | 0.5 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
| 0.1 | 0.4 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 1.4 | GO:0032727 | positive regulation of interferon-alpha production(GO:0032727) |
| 0.1 | 0.3 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 0.6 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
| 0.1 | 0.5 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
| 0.1 | 0.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.9 | GO:0045329 | amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329) |
| 0.1 | 0.2 | GO:0060972 | left/right pattern formation(GO:0060972) |
| 0.1 | 0.3 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.1 | 1.2 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.1 | 0.3 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
| 0.1 | 0.5 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 0.4 | GO:0006930 | substrate-dependent cell migration, cell extension(GO:0006930) |
| 0.1 | 0.2 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 0.1 | 1.6 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.1 | 0.6 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 4.5 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.1 | 0.4 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.1 | 1.2 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.1 | 0.2 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.0 | 0.2 | GO:0015827 | tryptophan transport(GO:0015827) leucine import(GO:0060356) |
| 0.0 | 0.3 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
| 0.0 | 0.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 0.6 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.0 | 1.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0002220 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) |
| 0.0 | 1.7 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.0 | 0.3 | GO:0015755 | fructose transport(GO:0015755) |
| 0.0 | 0.7 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
| 0.0 | 0.2 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.0 | 0.3 | GO:0055015 | ventricular cardiac muscle cell development(GO:0055015) |
| 0.0 | 0.3 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 0.4 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.0 | 0.2 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.0 | 0.2 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 1.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 0.5 | GO:0006702 | androgen biosynthetic process(GO:0006702) |
| 0.0 | 0.1 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 0.4 | GO:0032817 | regulation of natural killer cell proliferation(GO:0032817) |
| 0.0 | 0.2 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.0 | 0.7 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0005984 | disaccharide metabolic process(GO:0005984) oligosaccharide catabolic process(GO:0009313) polysaccharide digestion(GO:0044245) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.1 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) |
| 0.0 | 0.2 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.1 | GO:0000019 | regulation of mitotic recombination(GO:0000019) |
| 0.0 | 0.4 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.5 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.0 | 0.3 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.2 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
| 0.0 | 0.2 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.0 | 0.4 | GO:0007128 | meiotic prophase I(GO:0007128) |
| 0.0 | 0.5 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
| 0.0 | 0.1 | GO:0048488 | synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583) |
| 0.0 | 0.3 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.0 | 0.3 | GO:0002070 | epithelial cell maturation(GO:0002070) |
| 0.0 | 0.6 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 0.2 | GO:0019953 | sexual reproduction(GO:0019953) |
| 0.0 | 0.4 | GO:0001709 | cell fate determination(GO:0001709) |
| 0.0 | 0.2 | GO:0033523 | histone H2B ubiquitination(GO:0033523) |
| 0.0 | 0.1 | GO:1904396 | regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396) |
| 0.0 | 0.1 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.0 | 0.2 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
| 0.0 | 0.5 | GO:0019827 | stem cell population maintenance(GO:0019827) |
| 0.0 | 0.2 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.0 | 0.0 | GO:0035269 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502) |
| 0.0 | 0.1 | GO:0006000 | fructose metabolic process(GO:0006000) fructose 6-phosphate metabolic process(GO:0006002) |
| 0.0 | 1.3 | GO:0006096 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.0 | 2.4 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
| 0.0 | 1.2 | GO:0009062 | fatty acid catabolic process(GO:0009062) |
| 0.0 | 0.1 | GO:0042118 | endothelial cell activation(GO:0042118) regulation of endothelial cell differentiation(GO:0045601) |
| 0.0 | 0.6 | GO:0005978 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.0 | 0.1 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.3 | GO:0050771 | negative regulation of axonogenesis(GO:0050771) |
| 0.0 | 0.1 | GO:0055075 | potassium ion homeostasis(GO:0055075) |
| 0.0 | 0.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 0.0 | GO:0001969 | activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 0.0 | 0.1 | GO:0097696 | JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696) |
| 0.0 | 0.5 | GO:0048678 | response to axon injury(GO:0048678) |
| 0.0 | 0.3 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 0.3 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.0 | 0.1 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.1 | GO:0070295 | renal water absorption(GO:0070295) |
| 0.0 | 0.8 | GO:0008213 | protein methylation(GO:0006479) protein alkylation(GO:0008213) |
| 0.0 | 0.2 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403) |
| 0.0 | 0.8 | GO:0042476 | odontogenesis(GO:0042476) |
| 0.0 | 0.2 | GO:0008635 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635) |
| 0.0 | 1.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.2 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.2 | 2.0 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 1.1 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.7 | GO:0019718 | obsolete rough microsome(GO:0019718) |
| 0.1 | 0.4 | GO:0005787 | signal peptidase complex(GO:0005787) |
| 0.1 | 1.1 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.9 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 0.9 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.1 | 1.1 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 0.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 2.0 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 0.5 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.1 | 0.5 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 1.5 | GO:0043205 | fibril(GO:0043205) |
| 0.1 | 0.4 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 1.2 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.1 | 3.4 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 0.2 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.1 | 4.7 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.1 | 0.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.4 | GO:0071944 | cell periphery(GO:0071944) |
| 0.0 | 0.6 | GO:0005838 | proteasome regulatory particle(GO:0005838) |
| 0.0 | 0.2 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 0.1 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.0 | 0.5 | GO:0045120 | pronucleus(GO:0045120) |
| 0.0 | 0.3 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
| 0.0 | 0.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 1.4 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.7 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) |
| 0.0 | 0.1 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 0.8 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 1.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.2 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681) |
| 0.0 | 0.1 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.6 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.5 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.2 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.0 | GO:0031501 | mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.0 | 0.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.1 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.0 | 0.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 0.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.3 | GO:0001772 | immunological synapse(GO:0001772) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.4 | 4.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.4 | 1.2 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.4 | 2.5 | GO:0055105 | ubiquitin-protein transferase inhibitor activity(GO:0055105) |
| 0.3 | 1.0 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 0.3 | 1.0 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.2 | 1.2 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.2 | 0.7 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.2 | 5.4 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.2 | 0.7 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.2 | 1.1 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 0.7 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 1.0 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.2 | 2.0 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.2 | 4.2 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 1.8 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.1 | 3.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.1 | 0.7 | GO:0005000 | vasopressin receptor activity(GO:0005000) |
| 0.1 | 0.4 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.1 | 1.1 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 0.4 | GO:0005137 | interleukin-5 receptor binding(GO:0005137) |
| 0.1 | 0.4 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.1 | 1.8 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.1 | 0.6 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.1 | 2.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.3 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.1 | 0.4 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.1 | 0.4 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
| 0.1 | 1.2 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 0.3 | GO:0004083 | bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619) |
| 0.1 | 0.3 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 0.1 | 0.2 | GO:0004376 | glycolipid mannosyltransferase activity(GO:0004376) |
| 0.1 | 1.1 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 0.5 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.1 | 0.5 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 1.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 0.3 | GO:0016972 | thiol oxidase activity(GO:0016972) |
| 0.1 | 0.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 0.1 | 0.9 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.1 | 0.5 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 0.1 | 0.5 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.1 | 0.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 0.6 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 0.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.2 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.1 | 0.2 | GO:0000104 | succinate dehydrogenase activity(GO:0000104) |
| 0.1 | 0.5 | GO:0051425 | acetylcholine receptor binding(GO:0033130) PTB domain binding(GO:0051425) |
| 0.1 | 0.2 | GO:0046703 | beta-2-microglobulin binding(GO:0030881) natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.2 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 1.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.2 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.0 | 0.5 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
| 0.0 | 0.2 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.0 | 0.3 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.0 | 0.8 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.0 | 0.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.2 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.0 | 0.1 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.0 | 0.2 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.0 | 4.3 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.0 | 0.7 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.2 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 0.0 | 0.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.0 | 0.2 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.0 | 0.1 | GO:0050473 | hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.0 | 0.4 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.0 | 0.1 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 1.0 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.6 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.3 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 2.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.0 | 0.5 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.0 | 0.1 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.0 | 0.3 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.0 | 0.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.0 | 0.1 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 7.3 | GO:0003779 | actin binding(GO:0003779) |
| 0.0 | 0.0 | GO:0019962 | interferon binding(GO:0019961) type I interferon binding(GO:0019962) |
| 0.0 | 0.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.3 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.3 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.3 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
| 0.0 | 0.2 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.1 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.0 | 2.4 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 1.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.1 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
| 0.0 | 2.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.1 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 2.5 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.8 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 2.1 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
