Motif ID: SREBF1_TFE3

Z-value: 2.129

Transcription factors associated with SREBF1_TFE3:

Gene SymbolEntrez IDGene Name
SREBF1 ENSG00000072310.12 SREBF1
TFE3 ENSG00000068323.12 TFE3






Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1_TFE3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_10764509 7.882 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr20_+_44519948 6.791 ENST00000354880.5
ENST00000191018.5
CTSA

cathepsin A

chr20_+_44520009 6.334 ENST00000607482.1
ENST00000372459.2
CTSA

cathepsin A

chr9_+_706842 5.558 ENST00000382293.3
KANK1
KN motif and ankyrin repeat domains 1
chr17_+_78075498 5.073 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr13_+_113951532 4.863 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr16_-_5083589 4.842 ENST00000563578.1
ENST00000562346.2
NAGPA

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chr19_+_49458107 4.752 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX






BCL2-associated X protein






chr17_+_78075361 4.564 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr1_+_11866207 4.465 ENST00000312413.6
ENST00000346436.6
CLCN6

chloride channel, voltage-sensitive 6

chr16_-_5083917 4.203 ENST00000312251.3
ENST00000381955.3
NAGPA

N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

chrX_+_102631844 4.111 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chrX_-_102319092 3.980 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chrX_+_102631248 3.918 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chrY_+_15016725 3.816 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_-_121413974 3.730 ENST00000231004.4
LOX
lysyl oxidase
chrX_-_34675391 3.606 ENST00000275954.3
TMEM47
transmembrane protein 47
chr6_+_151646800 3.486 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr8_-_13134045 3.480 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr2_+_46926326 3.464 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr16_-_88923285 3.439 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr5_+_34656331 3.115 ENST00000265109.3
RAI14
retinoic acid induced 14
chr5_+_34656569 3.089 ENST00000428746.2
RAI14
retinoic acid induced 14
chr19_+_10764937 3.068 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr17_-_7137857 2.847 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr6_+_151561085 2.837 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr17_+_79935418 2.758 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr12_+_66217911 2.706 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr3_-_49395705 2.634 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr17_+_79935464 2.578 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr1_-_161193349 2.568 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2






apolipoprotein A-II






chr7_-_47621736 2.539 ENST00000311160.9
TNS3
tensin 3
chr1_+_11866270 2.524 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6


chloride channel, voltage-sensitive 6


chr3_-_49395892 2.503 ENST00000419783.1
GPX1
glutathione peroxidase 1
chr11_-_1785139 2.480 ENST00000236671.2
CTSD
cathepsin D
chr1_-_154193009 2.462 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43


chromosome 1 open reading frame 43


chr10_+_46222648 2.461 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
FAM21C





family with sequence similarity 21, member C





chrY_+_2709527 2.441 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr19_-_15236562 2.419 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr9_+_133320301 2.399 ENST00000352480.5
ASS1
argininosuccinate synthase 1
chr2_-_238499303 2.359 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr10_+_7745232 2.341 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_+_52776228 2.314 ENST00000256759.3
FST
follistatin
chr6_+_123110465 2.237 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr8_-_27457494 2.228 ENST00000521770.1
CLU
clusterin
chr2_+_220042933 2.185 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr10_+_7745303 2.152 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chrX_+_102840408 2.142 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4








transcription elongation factor A (SII)-like 4








chr22_+_35776828 2.120 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr5_+_52776449 2.064 ENST00000396947.3
FST
follistatin
chr17_-_7137582 2.062 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr6_+_151561506 2.056 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr8_+_136469684 2.055 ENST00000355849.5
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr6_+_123110302 2.050 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr14_-_81687575 2.017 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr17_+_42422662 2.000 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN






granulin






chr9_-_131709858 1.992 ENST00000372586.3
DOLK
dolichol kinase
chr19_-_15236470 1.975 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL


ilvB (bacterial acetolactate synthase)-like


chr2_-_183903133 1.943 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr5_-_133706695 1.847 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3





cyclin-dependent kinase-like 3





chr9_+_133320339 1.806 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
ASS1


argininosuccinate synthase 1


chr6_+_148663729 1.799 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr12_-_63328817 1.791 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr5_-_42811986 1.765 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1


selenoprotein P, plasma, 1


chr22_+_39916558 1.724 ENST00000337304.2
ENST00000396680.1
ATF4

activating transcription factor 4

chr21_+_38445539 1.724 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chrX_+_30671476 1.716 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr19_-_5680499 1.715 ENST00000587589.1
C19orf70
chromosome 19 open reading frame 70
chr2_-_227664474 1.703 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr14_-_94856987 1.672 ENST00000449399.3
ENST00000404814.4
SERPINA1

serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

chr2_+_46926048 1.667 ENST00000306503.5
SOCS5
suppressor of cytokine signaling 5
chr17_+_42422637 1.666 ENST00000053867.3
ENST00000588143.1
GRN

granulin

chr17_-_73975444 1.636 ENST00000293217.5
ENST00000537812.1
ACOX1

acyl-CoA oxidase 1, palmitoyl

chr14_-_94856951 1.628 ENST00000553327.1
ENST00000556955.1
ENST00000557118.1
ENST00000440909.1
SERPINA1



serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1



chr2_-_26101314 1.615 ENST00000336112.4
ENST00000272341.4
ASXL2

additional sex combs like 2 (Drosophila)

chr16_-_30134524 1.605 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr19_+_40854559 1.605 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
PLD3








phospholipase D family, member 3








chr14_-_94857004 1.584 ENST00000557492.1
ENST00000448921.1
ENST00000437397.1
ENST00000355814.4
ENST00000393088.4
SERPINA1




serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1




chr16_-_4588469 1.560 ENST00000588381.1
ENST00000563332.2
CDIP1

cell death-inducing p53 target 1

chr19_+_41256764 1.545 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA



small nuclear ribonucleoprotein polypeptide A



chr15_+_44084040 1.539 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr12_-_91539918 1.523 ENST00000548218.1
DCN
decorin
chr17_-_76975925 1.522 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP





lectin, galactoside-binding, soluble, 3 binding protein





chr2_+_219646462 1.517 ENST00000258415.4
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr12_-_103310987 1.503 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr4_-_89978299 1.501 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A



family with sequence similarity 13, member A



chr5_-_1112141 1.500 ENST00000264930.5
SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
chr1_-_241520525 1.493 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr16_+_69796209 1.493 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WWP2



WW domain containing E3 ubiquitin protein ligase 2



chr15_-_72668185 1.493 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr15_+_44084503 1.487 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2







small EDRK-rich factor 2







chr16_+_8806800 1.487 ENST00000561870.1
ENST00000396600.2
ABAT

4-aminobutyrate aminotransferase

chr2_-_242254595 1.476 ENST00000441124.1
ENST00000391976.2
HDLBP

high density lipoprotein binding protein

chr15_-_73925651 1.454 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
NPTN


neuroplastin


chr17_-_6915646 1.438 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2




Uncharacterized protein




chr2_-_26101374 1.434 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr4_+_169418195 1.430 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr6_+_31865552 1.408 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr17_-_73851285 1.406 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2







WW domain binding protein 2







chr5_+_150404904 1.392 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr19_+_5681011 1.389 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L









hydroxysteroid (11-beta) dehydrogenase 1-like









chr22_+_38609538 1.377 ENST00000407965.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr3_-_50360192 1.368 ENST00000442581.1
ENST00000447092.1
ENST00000357750.4
HYAL2


hyaluronoglucosaminidase 2


chr2_+_242254679 1.362 ENST00000428282.1
ENST00000360051.3
SEPT2

septin 2

chr7_-_27183263 1.358 ENST00000222726.3
HOXA5
homeobox A5
chr10_+_51827648 1.346 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
FAM21A


family with sequence similarity 21, member A


chr17_+_3539744 1.331 ENST00000046640.3
ENST00000381870.3
CTNS

cystinosin, lysosomal cystine transporter

chr16_-_58718611 1.312 ENST00000564100.1
ENST00000570101.1
SLC38A7

solute carrier family 38, member 7

chr9_-_19127474 1.308 ENST00000380465.3
ENST00000380464.3
ENST00000411567.1
ENST00000276914.2
PLIN2



perilipin 2



chrX_+_101975643 1.296 ENST00000361229.4
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr14_-_54420133 1.293 ENST00000559501.1
ENST00000558984.1
BMP4

bone morphogenetic protein 4

chr14_-_68283291 1.287 ENST00000555452.1
ENST00000347230.4
ZFYVE26

zinc finger, FYVE domain containing 26

chr12_+_6309963 1.286 ENST00000382515.2
CD9
CD9 molecule
chr18_-_21977748 1.274 ENST00000399441.4
ENST00000319481.3
OSBPL1A

oxysterol binding protein-like 1A

chr12_-_65153175 1.273 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
GNS


glucosamine (N-acetyl)-6-sulfatase


chr9_+_6757634 1.272 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C



lysine (K)-specific demethylase 4C



chrX_+_101975619 1.270 ENST00000457056.1
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr20_-_33413416 1.263 ENST00000359003.2
NCOA6
nuclear receptor coactivator 6
chr14_-_69445968 1.262 ENST00000438964.2
ACTN1
actinin, alpha 1
chr2_-_175870085 1.258 ENST00000409156.3
CHN1
chimerin 1
chr8_-_18541603 1.256 ENST00000428502.2
PSD3
pleckstrin and Sec7 domain containing 3
chrY_+_15016013 1.256 ENST00000360160.4
ENST00000454054.1
DDX3Y

DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked

chr5_-_172198190 1.251 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr5_+_150827143 1.246 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1


solute carrier family 36 (proton/amino acid symporter), member 1


chr22_+_38597889 1.236 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF



v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F



chr2_-_238499725 1.232 ENST00000264601.3
RAB17
RAB17, member RAS oncogene family
chr1_-_241520385 1.225 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr6_-_31830655 1.225 ENST00000375631.4
NEU1
sialidase 1 (lysosomal sialidase)
chr8_-_103668114 1.217 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr7_-_30029574 1.216 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
SCRN1


secernin 1


chr20_+_11898507 1.212 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr2_-_190044480 1.207 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr21_-_27542972 1.187 ENST00000346798.3
ENST00000439274.2
ENST00000354192.3
ENST00000348990.5
ENST00000357903.3
ENST00000358918.3
ENST00000359726.3
APP






amyloid beta (A4) precursor protein






chr12_-_110434183 1.182 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
GIT2





G protein-coupled receptor kinase interacting ArfGAP 2





chr16_-_1876779 1.179 ENST00000569339.1
ENST00000455446.2
ENST00000397353.2
HAGH


hydroxyacylglutathione hydrolase


chrX_+_102883887 1.178 ENST00000372625.3
ENST00000372624.3
TCEAL1

transcription elongation factor A (SII)-like 1

chr2_-_20251744 1.178 ENST00000175091.4
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr2_-_238499131 1.164 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chrX_+_146993534 1.159 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1


fragile X mental retardation 1


chr9_-_79307096 1.149 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr19_+_11546093 1.147 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr11_+_101981169 1.131 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1



Yes-associated protein 1



chr10_+_101542462 1.130 ENST00000370449.4
ENST00000370434.1
ABCC2

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

chr16_-_68269971 1.129 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr2_+_102508955 1.111 ENST00000414004.2
FLJ20373
FLJ20373
chr19_+_13049413 1.103 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr9_+_115913222 1.100 ENST00000259392.3
SLC31A2
solute carrier family 31 (copper transporter), member 2
chr7_-_30029367 1.097 ENST00000242059.5
SCRN1
secernin 1
chr4_-_100242549 1.096 ENST00000305046.8
ENST00000394887.3
ADH1B

alcohol dehydrogenase 1B (class I), beta polypeptide

chr15_-_77197620 1.079 ENST00000565970.1
ENST00000563290.1
ENST00000565372.1
ENST00000564177.1
ENST00000568382.1
ENST00000563919.1
SCAPER





S-phase cyclin A-associated protein in the ER





chr2_+_242254507 1.078 ENST00000391973.2
SEPT2
septin 2
chrY_+_16636354 1.077 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr14_-_69446034 1.073 ENST00000193403.6
ACTN1
actinin, alpha 1
chr2_+_228189867 1.061 ENST00000423098.1
ENST00000304593.9
MFF

mitochondrial fission factor

chr6_+_160390102 1.061 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr4_+_128651530 1.055 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr19_+_11546153 1.054 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr17_-_39093672 1.053 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23


keratin 23 (histone deacetylase inducible)


chr14_-_81687197 1.052 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr19_+_42212501 1.048 ENST00000398599.4
CEACAM5
carcinoembryonic antigen-related cell adhesion molecule 5
chr7_-_29186008 1.041 ENST00000396276.3
ENST00000265394.5
CPVL

carboxypeptidase, vitellogenic-like

chr7_-_27169801 1.039 ENST00000511914.1
HOXA4
homeobox A4
chr2_+_46524537 1.038 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr14_+_45431379 1.036 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B


family with sequence similarity 179, member B


chr4_+_39184024 1.027 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
WDR19




WD repeat domain 19




chr11_+_86511569 1.021 ENST00000441050.1
PRSS23
protease, serine, 23
chr6_-_33385870 1.011 ENST00000488034.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr8_+_59465728 1.003 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP






syndecan binding protein (syntenin)






chr9_+_103235365 1.000 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_33385902 0.999 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr1_+_221051699 0.999 ENST00000366903.6
HLX
H2.0-like homeobox
chr6_+_31895467 0.990 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr17_+_17876127 0.981 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr1_-_153508460 0.980 ENST00000462776.2
S100A6
S100 calcium binding protein A6
chr17_+_73975292 0.972 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1




TEN1 CST complex subunit




chr2_+_228189941 0.971 ENST00000353339.3
ENST00000354503.6
ENST00000530359.1
ENST00000531278.1
ENST00000409565.1
ENST00000452930.1
ENST00000409616.1
ENST00000337110.7
ENST00000525195.1
ENST00000534203.1
ENST00000524634.1
ENST00000349901.7
MFF











mitochondrial fission factor











chr2_-_238499337 0.971 ENST00000411462.1
ENST00000409822.1
RAB17

RAB17, member RAS oncogene family

chr20_+_56884752 0.970 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr14_-_69445793 0.970 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr11_-_75201791 0.968 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr3_-_122512619 0.962 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr2_+_42396574 0.955 ENST00000401738.3
EML4
echinoderm microtubule associated protein like 4
chr6_+_31895480 0.949 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2

CFB
complement component 2

Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895254 0.948 ENST00000299367.5
ENST00000442278.2
C2

complement component 2

chr2_-_242255117 0.945 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
HDLBP


high density lipoprotein binding protein


chr16_+_66914264 0.931 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr1_+_183605200 0.922 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr10_+_99258625 0.917 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr6_+_87865262 0.914 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr17_+_19552036 0.912 ENST00000581518.1
ENST00000395575.2
ENST00000584332.2
ENST00000339618.4
ENST00000579855.1
ALDH3A2




aldehyde dehydrogenase 3 family, member A2




chr10_-_126849588 0.908 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr3_+_51428704 0.908 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr9_-_32552551 0.907 ENST00000360538.2
ENST00000379858.1
TOPORS

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

chr3_+_134204551 0.902 ENST00000332047.5
ENST00000354446.3
CEP63

centrosomal protein 63kDa

chr4_-_186733363 0.900 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr8_+_21915368 0.897 ENST00000265800.5
ENST00000517418.1
DMTN

dematin actin binding protein

chr13_+_113951607 0.889 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr10_-_74385811 0.886 ENST00000603011.1
ENST00000401998.3
ENST00000361114.5
ENST00000604238.1
MICU1



mitochondrial calcium uptake 1



chr8_+_11561660 0.885 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA4


GATA binding protein 4


chr6_-_43484718 0.885 ENST00000372422.2
YIPF3
Yip1 domain family, member 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0003011 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
2.1 4.2 GO:0010046 response to mycotoxin(GO:0010046)
1.7 5.1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
1.6 4.9 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.6 4.8 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
1.3 5.1 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
1.2 4.9 GO:0033986 response to methanol(GO:0033986) response to chromate(GO:0046687)
1.1 10.1 GO:0006622 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.9 2.6 GO:2000910 regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910)
0.8 8.4 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 4.5 GO:0046882 negative regulation of gonadotropin secretion(GO:0032277) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.7 2.1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) negative regulation of leukocyte degranulation(GO:0043301)
0.6 2.3 GO:0001575 globoside metabolic process(GO:0001575)
0.6 1.7 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.5 1.6 GO:1990170 detoxification of cadmium ion(GO:0071585) stress response to cadmium ion(GO:1990170)
0.5 0.5 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.5 1.5 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.5 4.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.5 1.5 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.5 1.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.5 2.8 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.5 1.4 GO:0060574 intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.4 6.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 1.3 GO:0048389 intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) branch elongation involved in ureteric bud branching(GO:0060681) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) pattern specification involved in mesonephros development(GO:0061227) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) regulation of branch elongation involved in ureteric bud branching(GO:0072095) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) nephric duct formation(GO:0072179) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4 1.3 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.4 3.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 2.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.4 1.9 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.4 2.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)
0.4 1.1 GO:0002124 territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625)
0.3 8.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.3 2.6 GO:0006689 ganglioside catabolic process(GO:0006689)
0.3 3.6 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.3 1.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.3 0.6 GO:0051014 actin filament severing(GO:0051014)
0.3 0.9 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) intestinal epithelial cell differentiation(GO:0060575)
0.3 1.8 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 1.7 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.3 0.8 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.2 1.3 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.2 0.7 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.2 2.0 GO:0018126 protein hydroxylation(GO:0018126)
0.2 1.7 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 2.7 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 1.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.2 0.6 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 0.8 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.2 1.1 GO:0060242 contact inhibition(GO:0060242)
0.2 2.8 GO:0007567 parturition(GO:0007567)
0.2 0.7 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 2.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 1.5 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 0.5 GO:0060596 mammary placode formation(GO:0060596)
0.2 2.8 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.2 0.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 2.4 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.2 1.1 GO:0033034 positive regulation of myeloid cell apoptotic process(GO:0033034) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 3.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.4 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.6 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.1 1.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 2.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.6 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.5 GO:0046778 modification by virus of host mRNA processing(GO:0046778)
0.1 0.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 6.0 GO:0006914 autophagy(GO:0006914)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.1 0.1 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 0.6 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 1.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.1 1.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 5.4 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 5.9 GO:0046324 regulation of glucose import(GO:0046324)
0.1 1.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.9 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.8 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.1 0.7 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 1.5 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 0.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 1.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 2.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.1 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.3 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 2.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.2 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.1 1.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.5 GO:0009750 response to fructose(GO:0009750)
0.1 1.3 GO:0033574 response to testosterone(GO:0033574)
0.1 0.2 GO:0050983 spermidine catabolic process(GO:0046203) deoxyhypusine biosynthetic process from spermidine(GO:0050983)
0.1 1.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.7 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.3 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.1 1.4 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0007492 endoderm development(GO:0007492)
0.1 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.1 2.2 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.4 GO:0090342 regulation of cell aging(GO:0090342)
0.1 1.0 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 1.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.8 GO:0008272 sulfate transport(GO:0008272)
0.1 0.2 GO:0021570 rhombomere 4 development(GO:0021570) facial nucleus development(GO:0021754)
0.1 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0032898 neurotrophin production(GO:0032898)
0.1 0.9 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.2 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) transsulfuration(GO:0019346) homocysteine catabolic process(GO:0043418)
0.1 0.9 GO:0007032 endosome organization(GO:0007032)
0.1 1.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 1.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.1 6.6 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1 2.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 6.8 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281)
0.1 0.2 GO:1903825 organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039)
0.1 0.1 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.1 1.2 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0032914 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908) positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 2.0 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.0 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 1.7 GO:0051789 obsolete response to protein(GO:0051789)
0.0 0.8 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:0046618 drug transmembrane transport(GO:0006855) drug export(GO:0046618)
0.0 0.2 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 1.1 GO:0030030 cell projection organization(GO:0030030)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.9 GO:0046464 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 0.1 GO:1903301 lactate metabolic process(GO:0006089) regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.6 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.0 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.0 0.3 GO:0071166 ribonucleoprotein complex localization(GO:0071166) ribonucleoprotein complex export from nucleus(GO:0071426)
0.0 7.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 3.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0034287 type B pancreatic cell differentiation(GO:0003309) detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.6 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.7 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 1.5 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.1 GO:0007569 cell aging(GO:0007569)
0.0 0.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.0 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.2 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.8 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 2.0 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0072332 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.6 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0051297 centrosome organization(GO:0051297)
0.0 0.2 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.3 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.7 GO:0000910 cytokinesis(GO:0000910)
0.0 0.0 GO:0043084 penile erection(GO:0043084)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 3.0 GO:0007067 mitotic nuclear division(GO:0007067)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.7 4.2 GO:0070852 cell body fiber(GO:0070852)
0.7 2.8 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.4 3.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 1.8 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.7 GO:0005899 insulin receptor complex(GO:0005899)
0.3 4.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.3 1.9 GO:0051233 spindle midzone(GO:0051233)
0.3 5.9 GO:0005771 multivesicular body(GO:0005771)
0.3 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 2.2 GO:0000145 exocyst(GO:0000145)
0.2 0.7 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772)
0.2 1.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.2 3.3 GO:0031143 pseudopodium(GO:0031143)
0.2 4.8 GO:0046930 pore complex(GO:0046930)
0.2 1.4 GO:0042788 polysomal ribosome(GO:0042788)
0.2 0.8 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.2 2.8 GO:0071203 WASH complex(GO:0071203)
0.2 1.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 3.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 3.4 GO:0005844 polysome(GO:0005844)
0.1 18.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 9.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.9 GO:0042587 glycogen granule(GO:0042587)
0.1 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.1 0.5 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 1.9 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 19.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.5 GO:0005581 collagen trimer(GO:0005581)
0.1 1.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.7 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 13.7 GO:0005938 cell cortex(GO:0005938)
0.1 1.0 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 5.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.9 GO:0005858 axonemal dynein complex(GO:0005858) axoneme part(GO:0044447)
0.1 4.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 4.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 3.8 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.9 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 3.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 1.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 3.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 2.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 1.7 GO:0030133 transport vesicle(GO:0030133)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.0 0.6 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 24.6 GO:0005576 extracellular region(GO:0005576)
0.0 5.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.0 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.5 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.7 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.6 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
1.8 14.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
1.0 8.4 GO:0008179 adenylate cyclase binding(GO:0008179)
1.0 4.8 GO:0051434 BH3 domain binding(GO:0051434)
0.9 2.8 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.7 2.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.7 13.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.6 2.6 GO:0034190 apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653)
0.6 2.8 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 2.7 GO:0003680 AT DNA binding(GO:0003680)
0.5 1.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.5 4.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.5 2.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.5 1.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.5 1.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.4 4.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.4 1.8 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.4 1.3 GO:0043199 sulfate binding(GO:0043199)
0.4 1.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.4 1.5 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.4 1.5 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.4 1.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 4.0 GO:0015643 toxic substance binding(GO:0015643)
0.4 6.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.4 1.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.3 6.9 GO:0017166 vinculin binding(GO:0017166)
0.3 1.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.3 4.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 1.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3 1.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 3.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.3 1.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 4.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 2.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 1.9 GO:0001848 complement binding(GO:0001848)
0.2 0.7 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.2 5.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 2.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 3.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 5.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542)
0.2 4.6 GO:0005109 frizzled binding(GO:0005109)
0.2 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 1.9 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.8 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.6 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.2 0.7 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.2 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 2.5 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.8 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 1.1 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.2 0.5 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.2 1.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.9 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 5.2 GO:0002020 protease binding(GO:0002020)
0.1 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 2.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 6.7 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 2.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 1.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.3 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.5 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 1.2 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 4.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.3 GO:0050816 beta-2 adrenergic receptor binding(GO:0031698) phosphothreonine binding(GO:0050816)
0.1 1.8 GO:0008430 selenium binding(GO:0008430)
0.1 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.1 0.9 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0033265 choline binding(GO:0033265)
0.1 0.2 GO:0034038 deoxyhypusine synthase activity(GO:0034038)
0.1 0.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.3 GO:0004461 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) lactose synthase activity(GO:0004461)
0.1 3.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.6 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.6 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.0 GO:0019843 rRNA binding(GO:0019843)
0.1 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 4.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.3 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 1.2 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 2.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 1.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 2.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.5 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 1.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.8 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0045030 A1 adenosine receptor binding(GO:0031686) UTP-activated nucleotide receptor activity(GO:0045030)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 2.4 GO:0008514 organic anion transmembrane transporter activity(GO:0008514)
0.0 0.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 1.5 GO:0017016 Ras GTPase binding(GO:0017016)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 1.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0003917 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 2.1 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.3 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0003774 motor activity(GO:0003774)
0.0 2.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.0 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 2.4 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.6 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 4.9 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 2.8 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.2 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.