Motif ID: TBX1
Z-value: 2.207
Transcription factors associated with TBX1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
TBX1 | ENSG00000184058.8 | TBX1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.6 | GO:1903961 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961) |
0.7 | 2.2 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) chromosome movement towards spindle pole(GO:0051305) |
0.7 | 2.7 | GO:0033986 | response to methanol(GO:0033986) response to chromate(GO:0046687) |
0.6 | 3.0 | GO:0003093 | regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801) |
0.6 | 3.0 | GO:0003070 | age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) |
0.6 | 2.4 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
0.6 | 2.2 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
0.5 | 1.6 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.5 | 1.6 | GO:2000910 | regulation of cholesterol import(GO:0060620) negative regulation of cholesterol import(GO:0060621) regulation of sterol import(GO:2000909) negative regulation of sterol import(GO:2000910) |
0.5 | 2.0 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.5 | 2.0 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.4 | 1.2 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.4 | 1.2 | GO:0010586 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) |
0.4 | 1.5 | GO:0051712 | positive regulation of killing of cells of other organism(GO:0051712) |
0.4 | 2.9 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.3 | 1.0 | GO:0003176 | aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180) notochord formation(GO:0014028) |
0.3 | 1.0 | GO:0009648 | photoperiodism(GO:0009648) |
0.3 | 3.0 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
0.3 | 3.3 | GO:0046643 | regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645) |
0.3 | 0.7 | GO:0048143 | astrocyte activation(GO:0048143) |
0.3 | 0.6 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.3 | 1.2 | GO:0002478 | antigen processing and presentation of exogenous peptide antigen(GO:0002478) |
0.3 | 1.1 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
0.3 | 0.8 | GO:0019521 | aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521) |
0.3 | 1.1 | GO:0033622 | integrin activation(GO:0033622) regulation of integrin activation(GO:0033623) positive regulation of integrin activation(GO:0033625) |
0.3 | 0.3 | GO:0071166 | ribonucleoprotein complex localization(GO:0071166) ribonucleoprotein complex export from nucleus(GO:0071426) |
0.3 | 1.3 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.3 | 0.8 | GO:0061298 | progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299) |
0.3 | 0.8 | GO:0003289 | septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) |
0.2 | 1.9 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.2 | 2.1 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
0.2 | 0.7 | GO:0009992 | cellular water homeostasis(GO:0009992) |
0.2 | 0.4 | GO:0046532 | regulation of photoreceptor cell differentiation(GO:0046532) |
0.2 | 0.9 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
0.2 | 1.3 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
0.2 | 0.4 | GO:0001704 | formation of primary germ layer(GO:0001704) |
0.2 | 0.9 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
0.2 | 0.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.2 | 0.6 | GO:0002291 | T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291) |
0.2 | 0.4 | GO:0016046 | detection of fungus(GO:0016046) |
0.2 | 1.5 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
0.2 | 0.4 | GO:0014874 | response to stimulus involved in regulation of muscle adaptation(GO:0014874) |
0.2 | 5.3 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
0.2 | 1.7 | GO:0006546 | glycine catabolic process(GO:0006546) |
0.2 | 0.7 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.2 | 1.1 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.2 | 0.9 | GO:0032736 | positive regulation of interleukin-13 production(GO:0032736) |
0.2 | 0.6 | GO:0015959 | diadenosine polyphosphate metabolic process(GO:0015959) |
0.2 | 0.7 | GO:0071436 | sodium ion export(GO:0071436) |
0.2 | 0.5 | GO:0046931 | pore complex assembly(GO:0046931) |
0.2 | 0.4 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
0.2 | 0.5 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.2 | 2.3 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
0.2 | 0.8 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
0.2 | 1.1 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.2 | 0.3 | GO:0032632 | interleukin-3 production(GO:0032632) |
0.2 | 0.5 | GO:0006273 | lagging strand elongation(GO:0006273) |
0.2 | 0.2 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
0.2 | 1.3 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.2 | 0.8 | GO:0060292 | long term synaptic depression(GO:0060292) |
0.2 | 1.0 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.2 | 0.2 | GO:0070849 | response to epidermal growth factor(GO:0070849) |
0.1 | 1.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
0.1 | 1.3 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.1 | 0.6 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
0.1 | 0.4 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 1.0 | GO:0016075 | rRNA catabolic process(GO:0016075) |
0.1 | 0.7 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
0.1 | 0.7 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.1 | 0.6 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.1 | 0.8 | GO:0030903 | notochord development(GO:0030903) |
0.1 | 0.6 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
0.1 | 0.6 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.1 | 0.4 | GO:0002677 | negative regulation of chronic inflammatory response(GO:0002677) |
0.1 | 0.7 | GO:0043306 | positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306) |
0.1 | 0.2 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698) |
0.1 | 0.1 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
0.1 | 0.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.4 | GO:0034625 | fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.1 | 0.2 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
0.1 | 0.1 | GO:0046984 | regulation of hemoglobin biosynthetic process(GO:0046984) |
0.1 | 0.6 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.1 | 0.5 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
0.1 | 0.7 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
0.1 | 2.7 | GO:0031648 | protein destabilization(GO:0031648) |
0.1 | 0.3 | GO:0031297 | replication fork processing(GO:0031297) |
0.1 | 0.3 | GO:1904036 | negative regulation of epithelial cell apoptotic process(GO:1904036) regulation of establishment of cell polarity(GO:2000114) negative regulation of endothelial cell apoptotic process(GO:2000352) |
0.1 | 0.5 | GO:0051958 | methotrexate transport(GO:0051958) |
0.1 | 0.7 | GO:0019985 | translesion synthesis(GO:0019985) |
0.1 | 0.3 | GO:0001938 | positive regulation of endothelial cell proliferation(GO:0001938) |
0.1 | 0.4 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
0.1 | 0.8 | GO:0090399 | replicative senescence(GO:0090399) |
0.1 | 1.9 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.1 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
0.1 | 0.5 | GO:0051852 | disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873) |
0.1 | 0.3 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.1 | 0.3 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.1 | 0.4 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
0.1 | 1.5 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
0.1 | 0.6 | GO:2000189 | regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189) |
0.1 | 0.7 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
0.1 | 1.1 | GO:0000050 | urea cycle(GO:0000050) arginine catabolic process(GO:0006527) |
0.1 | 0.3 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.1 | 0.3 | GO:0090274 | positive regulation of somatostatin secretion(GO:0090274) |
0.1 | 0.8 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 2.6 | GO:0030593 | neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266) |
0.1 | 0.5 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
0.1 | 3.0 | GO:0050830 | defense response to Gram-positive bacterium(GO:0050830) |
0.1 | 0.4 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.1 | 0.6 | GO:0015755 | fructose transport(GO:0015755) |
0.1 | 0.5 | GO:0006537 | glutamate biosynthetic process(GO:0006537) proline catabolic process(GO:0006562) |
0.1 | 2.2 | GO:0051923 | sulfation(GO:0051923) |
0.1 | 0.4 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
0.1 | 1.3 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.1 | 0.9 | GO:0071451 | removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
0.1 | 0.3 | GO:0071679 | cell proliferation in midbrain(GO:0033278) commissural neuron axon guidance(GO:0071679) |
0.1 | 1.4 | GO:0045730 | respiratory burst(GO:0045730) |
0.1 | 0.5 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.1 | 0.3 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.1 | 0.9 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
0.1 | 0.3 | GO:0009103 | lipopolysaccharide biosynthetic process(GO:0009103) |
0.1 | 0.6 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.1 | 0.3 | GO:0090267 | positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504) |
0.1 | 0.6 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
0.1 | 0.2 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
0.1 | 1.3 | GO:0006198 | cAMP catabolic process(GO:0006198) |
0.1 | 0.8 | GO:0016180 | snRNA processing(GO:0016180) |
0.1 | 0.2 | GO:0070482 | response to hypoxia(GO:0001666) response to decreased oxygen levels(GO:0036293) response to oxygen levels(GO:0070482) |
0.1 | 0.3 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064) |
0.1 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.1 | 0.2 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.1 | 0.5 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 2.1 | GO:0007052 | mitotic spindle organization(GO:0007052) |
0.1 | 0.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 0.6 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.1 | 0.8 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.1 | 0.2 | GO:0010216 | maintenance of DNA methylation(GO:0010216) |
0.1 | 0.3 | GO:0006922 | obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922) |
0.1 | 0.8 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
0.1 | 0.8 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.1 | 0.5 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
0.1 | 1.8 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
0.1 | 2.1 | GO:0007602 | phototransduction(GO:0007602) |
0.1 | 0.4 | GO:0015871 | choline transport(GO:0015871) |
0.1 | 0.7 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.1 | 0.3 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.1 | 0.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
0.1 | 0.9 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.1 | 1.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.1 | 0.5 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
0.1 | 0.1 | GO:0007059 | chromosome segregation(GO:0007059) |
0.1 | 0.6 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.1 | 0.1 | GO:0034014 | response to triglyceride(GO:0034014) |
0.1 | 0.5 | GO:0040001 | establishment of mitotic spindle localization(GO:0040001) |
0.1 | 0.4 | GO:0042416 | dopamine biosynthetic process(GO:0042416) |
0.1 | 0.4 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
0.1 | 3.1 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.1 | 0.4 | GO:0002544 | chronic inflammatory response(GO:0002544) |
0.1 | 0.2 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.1 | 0.5 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.1 | 1.2 | GO:0009086 | methionine biosynthetic process(GO:0009086) |
0.1 | 1.3 | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) |
0.1 | 0.4 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078) |
0.1 | 0.3 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
0.1 | 0.9 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
0.1 | 1.0 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
0.1 | 0.3 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.1 | 0.9 | GO:0060056 | mammary gland involution(GO:0060056) |
0.1 | 1.8 | GO:0051899 | membrane depolarization(GO:0051899) |
0.1 | 0.9 | GO:0042438 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
0.1 | 0.7 | GO:0002021 | response to dietary excess(GO:0002021) |
0.1 | 0.3 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.1 | 0.1 | GO:0048535 | lymph node development(GO:0048535) |
0.1 | 0.2 | GO:0010716 | regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054) |
0.1 | 0.5 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.1 | 0.4 | GO:0071243 | response to fungicide(GO:0060992) cellular response to arsenic-containing substance(GO:0071243) |
0.1 | 0.3 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.1 | 0.5 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 0.3 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
0.1 | 0.7 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
0.1 | 2.6 | GO:0042113 | B cell activation(GO:0042113) |
0.1 | 0.6 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.1 | 0.2 | GO:0046851 | negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851) |
0.1 | 0.1 | GO:0043551 | regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
0.1 | 0.5 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.1 | 0.1 | GO:0051971 | positive regulation of transmission of nerve impulse(GO:0051971) |
0.1 | 0.8 | GO:0030225 | macrophage differentiation(GO:0030225) |
0.1 | 0.6 | GO:0040023 | establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647) |
0.1 | 0.2 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.3 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
0.0 | 0.1 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
0.0 | 0.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 1.7 | GO:0006968 | cellular defense response(GO:0006968) |
0.0 | 0.5 | GO:0060351 | cartilage development involved in endochondral bone morphogenesis(GO:0060351) |
0.0 | 0.3 | GO:0010896 | regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898) |
0.0 | 0.4 | GO:0043174 | pyrimidine-containing compound salvage(GO:0008655) cellular metabolic compound salvage(GO:0043094) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174) |
0.0 | 0.2 | GO:0070265 | necrotic cell death(GO:0070265) |
0.0 | 0.2 | GO:0060023 | soft palate development(GO:0060023) |
0.0 | 0.5 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.0 | 0.2 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527) |
0.0 | 0.2 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.0 | 1.0 | GO:0031055 | DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641) |
0.0 | 1.2 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.4 | GO:0015074 | DNA integration(GO:0015074) |
0.0 | 1.4 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.1 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.0 | 0.2 | GO:0050665 | hydrogen peroxide biosynthetic process(GO:0050665) |
0.0 | 0.2 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.0 | 0.4 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.0 | 0.3 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
0.0 | 0.1 | GO:0006007 | glucose catabolic process(GO:0006007) |
0.0 | 2.4 | GO:0042742 | defense response to bacterium(GO:0042742) |
0.0 | 0.8 | GO:0035338 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
0.0 | 0.3 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.5 | GO:0032720 | negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556) |
0.0 | 1.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.6 | GO:0006400 | tRNA modification(GO:0006400) |
0.0 | 0.2 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.4 | GO:0019228 | neuronal action potential(GO:0019228) |
0.0 | 0.3 | GO:0035246 | peptidyl-arginine N-methylation(GO:0035246) |
0.0 | 0.2 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.0 | 0.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.1 | GO:0014887 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) |
0.0 | 0.2 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
0.0 | 2.5 | GO:0009636 | response to toxic substance(GO:0009636) |
0.0 | 0.1 | GO:0007090 | obsolete regulation of S phase of mitotic cell cycle(GO:0007090) |
0.0 | 0.8 | GO:0006691 | leukotriene metabolic process(GO:0006691) |
0.0 | 0.1 | GO:0009266 | response to temperature stimulus(GO:0009266) |
0.0 | 0.4 | GO:0006342 | chromatin silencing(GO:0006342) |
0.0 | 0.7 | GO:0006221 | pyrimidine nucleotide biosynthetic process(GO:0006221) |
0.0 | 0.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.1 | GO:0035929 | steroid hormone secretion(GO:0035929) |
0.0 | 0.1 | GO:0006884 | cell volume homeostasis(GO:0006884) |
0.0 | 0.7 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.1 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183) |
0.0 | 0.2 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
0.0 | 0.2 | GO:0007128 | meiotic prophase I(GO:0007128) meiosis I cell cycle phase(GO:0098764) |
0.0 | 0.1 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.0 | 0.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
0.0 | 0.8 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity(GO:0051092) |
0.0 | 0.2 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.0 | 0.5 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.0 | 0.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.5 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.0 | 0.4 | GO:0045954 | positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954) |
0.0 | 0.5 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 0.7 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
0.0 | 0.1 | GO:0045744 | negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744) |
0.0 | 0.3 | GO:0032259 | methylation(GO:0032259) |
0.0 | 0.3 | GO:0023058 | desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058) |
0.0 | 4.4 | GO:0008643 | carbohydrate transport(GO:0008643) |
0.0 | 0.1 | GO:0045896 | regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) |
0.0 | 0.1 | GO:0014831 | intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831) |
0.0 | 1.0 | GO:0006953 | acute-phase response(GO:0006953) |
0.0 | 0.2 | GO:0060122 | auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088) inner ear receptor stereocilium organization(GO:0060122) |
0.0 | 0.5 | GO:0046464 | neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464) |
0.0 | 0.2 | GO:0030238 | male sex determination(GO:0030238) |
0.0 | 0.2 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) negative regulation of stress fiber assembly(GO:0051497) |
0.0 | 0.3 | GO:1902001 | fatty acid transmembrane transport(GO:1902001) |
0.0 | 0.1 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.1 | GO:0015732 | prostaglandin transport(GO:0015732) |
0.0 | 0.9 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.0 | 0.8 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.1 | GO:0032570 | response to progesterone(GO:0032570) |
0.0 | 1.2 | GO:0007422 | peripheral nervous system development(GO:0007422) |
0.0 | 1.2 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
0.0 | 0.4 | GO:0006954 | inflammatory response(GO:0006954) |
0.0 | 1.7 | GO:0051592 | response to calcium ion(GO:0051592) |
0.0 | 0.0 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.1 | GO:0031635 | adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) opioid receptor signaling pathway(GO:0038003) |
0.0 | 0.1 | GO:1901798 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798) |
0.0 | 1.5 | GO:0000910 | cytokinesis(GO:0000910) |
0.0 | 0.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.5 | GO:0061077 | chaperone-mediated protein folding(GO:0061077) |
0.0 | 0.8 | GO:0007051 | spindle organization(GO:0007051) |
0.0 | 0.1 | GO:0018101 | citrulline metabolic process(GO:0000052) protein citrullination(GO:0018101) citrulline biosynthetic process(GO:0019240) |
0.0 | 3.2 | GO:0006813 | potassium ion transport(GO:0006813) |
0.0 | 0.2 | GO:0042098 | T cell proliferation(GO:0042098) |
0.0 | 0.3 | GO:0030317 | sperm motility(GO:0030317) |
0.0 | 0.4 | GO:0048146 | positive regulation of fibroblast proliferation(GO:0048146) |
0.0 | 1.1 | GO:0008033 | tRNA processing(GO:0008033) |
0.0 | 0.2 | GO:0048839 | inner ear development(GO:0048839) |
0.0 | 2.9 | GO:0048511 | rhythmic process(GO:0048511) |
0.0 | 0.2 | GO:1902582 | single-organism intracellular transport(GO:1902582) |
0.0 | 1.2 | GO:0007162 | negative regulation of cell adhesion(GO:0007162) |
0.0 | 0.1 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072) |
0.0 | 0.1 | GO:0055009 | atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) |
0.0 | 0.4 | GO:0030325 | adrenal gland development(GO:0030325) |
0.0 | 0.3 | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) |
0.0 | 0.1 | GO:0046718 | viral entry into host cell(GO:0046718) |
0.0 | 0.3 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.0 | 0.2 | GO:0048536 | spleen development(GO:0048536) |
0.0 | 0.7 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.0 | 0.2 | GO:0060334 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.0 | 0.5 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.8 | GO:0019079 | viral genome replication(GO:0019079) |
0.0 | 0.2 | GO:0060711 | labyrinthine layer development(GO:0060711) |
0.0 | 0.9 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 1.3 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
0.0 | 0.4 | GO:0072659 | protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778) |
0.0 | 0.4 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.0 | 0.5 | GO:0019221 | cytokine-mediated signaling pathway(GO:0019221) |
0.0 | 0.2 | GO:0097696 | JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696) |
0.0 | 1.1 | GO:0019882 | antigen processing and presentation(GO:0019882) |
0.0 | 2.0 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
0.0 | 0.3 | GO:0007188 | adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188) |
0.0 | 0.3 | GO:0016574 | histone ubiquitination(GO:0016574) |
0.0 | 0.5 | GO:0051318 | G1 phase(GO:0051318) |
0.0 | 1.4 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
0.0 | 0.6 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
0.0 | 0.2 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
0.0 | 0.0 | GO:0035455 | response to interferon-alpha(GO:0035455) |
0.0 | 1.1 | GO:0016055 | Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) cell surface receptor signaling pathway involved in cell-cell signaling(GO:1905114) |
0.0 | 0.5 | GO:0046847 | filopodium assembly(GO:0046847) |
0.0 | 0.5 | GO:0033344 | cholesterol efflux(GO:0033344) |
0.0 | 0.2 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 1.2 | GO:0046777 | protein autophosphorylation(GO:0046777) |
0.0 | 0.5 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
0.0 | 0.1 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.0 | 0.7 | GO:0031668 | cellular response to extracellular stimulus(GO:0031668) |
0.0 | 1.4 | GO:0007586 | digestion(GO:0007586) |
0.0 | 0.3 | GO:0050772 | positive regulation of cell morphogenesis involved in differentiation(GO:0010770) positive regulation of axonogenesis(GO:0050772) |
0.0 | 0.4 | GO:0006490 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.0 | 5.0 | GO:0050776 | regulation of immune response(GO:0050776) |
0.0 | 0.7 | GO:0050821 | protein stabilization(GO:0050821) |
0.0 | 1.0 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.0 | 0.2 | GO:0009994 | oocyte differentiation(GO:0009994) oocyte development(GO:0048599) |
0.0 | 0.9 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774) |
0.0 | 1.6 | GO:0006401 | RNA catabolic process(GO:0006401) |
0.0 | 0.2 | GO:0070206 | protein trimerization(GO:0070206) |
0.0 | 0.4 | GO:0019233 | sensory perception of pain(GO:0019233) |
0.0 | 0.1 | GO:0051259 | protein oligomerization(GO:0051259) |
0.0 | 0.2 | GO:0050906 | detection of stimulus involved in sensory perception(GO:0050906) |
0.0 | 0.1 | GO:0035587 | purinergic receptor signaling pathway(GO:0035587) purinergic nucleotide receptor signaling pathway(GO:0035590) |
0.0 | 0.2 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.0 | GO:0060346 | bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430) |
0.0 | 0.2 | GO:0000090 | mitotic anaphase(GO:0000090) anaphase(GO:0051322) |
0.0 | 0.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
0.0 | 0.4 | GO:0006885 | regulation of pH(GO:0006885) |
0.0 | 0.1 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
0.0 | 0.7 | GO:0006338 | chromatin remodeling(GO:0006338) |
0.0 | 0.1 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.0 | 0.1 | GO:0006349 | regulation of gene expression by genetic imprinting(GO:0006349) genetic imprinting(GO:0071514) |
0.0 | 0.1 | GO:0045056 | transcytosis(GO:0045056) |
0.0 | 0.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.0 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.2 | GO:0002697 | regulation of immune effector process(GO:0002697) |
0.0 | 0.0 | GO:0050942 | positive regulation of melanocyte differentiation(GO:0045636) positive regulation of developmental pigmentation(GO:0048087) positive regulation of pigment cell differentiation(GO:0050942) |
0.0 | 0.1 | GO:0045749 | obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749) |
0.0 | 0.2 | GO:0051591 | response to cAMP(GO:0051591) |
0.0 | 0.1 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 0.1 | GO:0051149 | positive regulation of muscle cell differentiation(GO:0051149) |
0.0 | 0.3 | GO:1900047 | negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047) |
0.0 | 0.5 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
0.0 | 0.0 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.0 | 1.0 | GO:0008203 | cholesterol metabolic process(GO:0008203) |
0.0 | 0.4 | GO:0071357 | response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.7 | GO:0032591 | dendritic spine membrane(GO:0032591) |
0.5 | 1.6 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.4 | 4.4 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.3 | 1.5 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.3 | 2.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.3 | 1.3 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.3 | 2.3 | GO:0005638 | lamin filament(GO:0005638) |
0.2 | 0.9 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
0.2 | 0.9 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.2 | 0.6 | GO:0042629 | mast cell granule(GO:0042629) |
0.2 | 2.1 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.2 | 0.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.2 | 1.4 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.1 | 3.1 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.1 | 2.1 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.1 | 0.6 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
0.1 | 1.8 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 0.9 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.1 | 0.9 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.1 | 0.7 | GO:0001741 | XY body(GO:0001741) |
0.1 | 1.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.1 | 1.3 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 1.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 0.3 | GO:0009279 | cell outer membrane(GO:0009279) |
0.1 | 0.5 | GO:0042581 | specific granule(GO:0042581) |
0.1 | 0.2 | GO:1990204 | oxidoreductase complex(GO:1990204) |
0.1 | 0.8 | GO:0005828 | kinetochore microtubule(GO:0005828) |
0.1 | 1.4 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 2.1 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.1 | 0.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.6 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
0.1 | 1.6 | GO:0042627 | chylomicron(GO:0042627) |
0.1 | 0.6 | GO:0005682 | U5 snRNP(GO:0005682) |
0.1 | 0.6 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 0.5 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.1 | 0.6 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.1 | 0.6 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.1 | 0.4 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.1 | 0.8 | GO:0032039 | integrator complex(GO:0032039) |
0.1 | 0.4 | GO:0032590 | dendrite membrane(GO:0032590) |
0.1 | 1.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.1 | 0.5 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.1 | 0.6 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.1 | 0.7 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.1 | 0.5 | GO:0070652 | HAUS complex(GO:0070652) |
0.1 | 1.0 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
0.1 | 1.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.1 | 0.5 | GO:0000796 | condensin complex(GO:0000796) |
0.1 | 3.6 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
0.1 | 0.2 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.1 | 0.7 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.1 | 0.8 | GO:0030315 | T-tubule(GO:0030315) |
0.1 | 0.2 | GO:0031213 | RSF complex(GO:0031213) |
0.1 | 0.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.1 | 1.3 | GO:0001772 | immunological synapse(GO:0001772) |
0.1 | 1.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 0.5 | GO:0000791 | euchromatin(GO:0000791) |
0.0 | 2.0 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 1.2 | GO:0042612 | MHC protein complex(GO:0042611) MHC class I protein complex(GO:0042612) |
0.0 | 3.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 0.4 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.6 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
0.0 | 0.4 | GO:0014704 | intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291) |
0.0 | 0.4 | GO:0016585 | obsolete chromatin remodeling complex(GO:0016585) |
0.0 | 0.3 | GO:0032389 | MutLalpha complex(GO:0032389) |
0.0 | 0.4 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.2 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 1.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.0 | 3.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 0.3 | GO:0030313 | NMDA selective glutamate receptor complex(GO:0017146) outer membrane-bounded periplasmic space(GO:0030288) cell envelope(GO:0030313) periplasmic space(GO:0042597) |
0.0 | 1.2 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.0 | 0.1 | GO:0071797 | LUBAC complex(GO:0071797) |
0.0 | 0.5 | GO:0005922 | connexon complex(GO:0005922) |
0.0 | 2.5 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.2 | GO:0005683 | U7 snRNP(GO:0005683) |
0.0 | 2.3 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
0.0 | 0.2 | GO:0001739 | sex chromatin(GO:0001739) |
0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 1.2 | GO:0043197 | dendritic spine(GO:0043197) |
0.0 | 0.2 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
0.0 | 0.3 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 1.3 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 2.0 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.3 | GO:0071778 | obsolete WINAC complex(GO:0071778) |
0.0 | 2.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 0.3 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.1 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 1.5 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
0.0 | 0.4 | GO:0070822 | Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822) |
0.0 | 2.6 | GO:0016607 | nuclear speck(GO:0016607) |
0.0 | 0.4 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 2.3 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.0 | 0.2 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
0.0 | 0.3 | GO:0030530 | obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530) |
0.0 | 0.1 | GO:0005827 | polar microtubule(GO:0005827) |
0.0 | 0.4 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
0.0 | 1.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.0 | GO:0060205 | cytoplasmic membrane-bounded vesicle lumen(GO:0060205) |
0.0 | 0.1 | GO:1902562 | H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 1.4 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.5 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 2.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.0 | 1.9 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
0.0 | 0.2 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.0 | 2.9 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 0.2 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 1.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
0.0 | 0.5 | GO:0000922 | spindle pole(GO:0000922) |
0.0 | 0.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.0 | 4.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.0 | 0.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.5 | GO:0005624 | obsolete membrane fraction(GO:0005624) |
0.0 | 0.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.2 | GO:0019861 | obsolete flagellum(GO:0019861) |
0.0 | 0.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.1 | GO:0019718 | obsolete rough microsome(GO:0019718) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 1.9 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.6 | 2.4 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
0.6 | 2.9 | GO:0080030 | methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
0.6 | 2.8 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
0.5 | 2.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.5 | 1.4 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.4 | 4.0 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
0.4 | 1.2 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.4 | 1.6 | GO:0034190 | apolipoprotein receptor binding(GO:0034190) high-density lipoprotein particle receptor binding(GO:0070653) |
0.4 | 1.2 | GO:0004913 | interleukin-4 receptor activity(GO:0004913) interleukin-2 binding(GO:0019976) |
0.4 | 3.0 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.4 | 1.1 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
0.3 | 0.7 | GO:0032089 | NACHT domain binding(GO:0032089) |
0.3 | 4.4 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.3 | 1.3 | GO:0003796 | lysozyme activity(GO:0003796) |
0.3 | 2.0 | GO:0032190 | acrosin binding(GO:0032190) |
0.3 | 0.3 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
0.3 | 0.9 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.3 | 5.3 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) |
0.3 | 0.6 | GO:0016151 | nickel cation binding(GO:0016151) |
0.3 | 1.6 | GO:0019863 | IgE binding(GO:0019863) |
0.3 | 1.3 | GO:0015216 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216) |
0.3 | 0.8 | GO:0047150 | betaine-homocysteine S-methyltransferase activity(GO:0047150) |
0.2 | 1.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.2 | 1.6 | GO:0004340 | glucokinase activity(GO:0004340) |
0.2 | 1.3 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
0.2 | 0.6 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859) |
0.2 | 1.7 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
0.2 | 4.5 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
0.2 | 1.0 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.2 | 0.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939) |
0.2 | 0.8 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.2 | 1.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.2 | 0.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.2 | 4.3 | GO:0005355 | glucose transmembrane transporter activity(GO:0005355) |
0.2 | 1.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.2 | 0.5 | GO:0050051 | leukotriene-B4 20-monooxygenase activity(GO:0050051) |
0.2 | 1.0 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.2 | 0.9 | GO:0005534 | galactose binding(GO:0005534) |
0.2 | 0.5 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
0.2 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.2 | 0.5 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
0.2 | 0.6 | GO:0047026 | androsterone dehydrogenase (A-specific) activity(GO:0047026) |
0.2 | 0.8 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.2 | 2.1 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.2 | 2.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.1 | 1.6 | GO:0050897 | cobalt ion binding(GO:0050897) |
0.1 | 1.0 | GO:0030492 | hemoglobin binding(GO:0030492) |
0.1 | 0.8 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
0.1 | 1.7 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 0.5 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.1 | 0.5 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
0.1 | 0.7 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.1 | 0.5 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
0.1 | 0.4 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.1 | 0.4 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
0.1 | 1.0 | GO:0004522 | ribonuclease A activity(GO:0004522) |
0.1 | 0.4 | GO:0004853 | uroporphyrinogen decarboxylase activity(GO:0004853) |
0.1 | 0.5 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
0.1 | 0.5 | GO:0032810 | sterol response element binding(GO:0032810) |
0.1 | 0.4 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.1 | 0.6 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 0.7 | GO:0004875 | complement receptor activity(GO:0004875) |
0.1 | 1.8 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.1 | 0.3 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
0.1 | 0.5 | GO:0015350 | methotrexate transporter activity(GO:0015350) |
0.1 | 0.8 | GO:0001846 | opsonin binding(GO:0001846) |
0.1 | 0.9 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.1 | 0.4 | GO:0008907 | integrase activity(GO:0008907) |
0.1 | 0.9 | GO:0050733 | RS domain binding(GO:0050733) |
0.1 | 1.8 | GO:0005521 | lamin binding(GO:0005521) |
0.1 | 5.1 | GO:0008009 | chemokine activity(GO:0008009) |
0.1 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.1 | 0.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 2.1 | GO:0043499 | obsolete eukaryotic cell surface binding(GO:0043499) |
0.1 | 1.5 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.1 | 0.3 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) |
0.1 | 2.0 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
0.1 | 0.9 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 0.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.1 | 0.9 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.1 | 0.3 | GO:0004951 | cholecystokinin receptor activity(GO:0004951) |
0.1 | 0.9 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.1 | 1.6 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 0.5 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
0.1 | 2.1 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.1 | 0.3 | GO:0043140 | bubble DNA binding(GO:0000405) ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
0.1 | 0.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.5 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
0.1 | 0.5 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.1 | 0.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.1 | 0.2 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
0.1 | 0.3 | GO:0009384 | N-acylmannosamine kinase activity(GO:0009384) |
0.1 | 0.3 | GO:0030337 | DNA polymerase processivity factor activity(GO:0030337) |
0.1 | 0.7 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
0.1 | 0.4 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.1 | 1.2 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.1 | 0.8 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.1 | 0.4 | GO:0005113 | patched binding(GO:0005113) |
0.1 | 0.3 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
0.1 | 0.3 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
0.1 | 0.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
0.1 | 0.4 | GO:0031708 | bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708) |
0.1 | 2.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 1.0 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
0.1 | 0.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 0.6 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 0.3 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
0.1 | 1.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 1.5 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.1 | 0.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.1 | 1.1 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.1 | 0.6 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.1 | 0.7 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.1 | 0.2 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 0.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
0.1 | 0.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
0.1 | 1.3 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.1 | 3.9 | GO:0004221 | obsolete ubiquitin thiolesterase activity(GO:0004221) |
0.1 | 0.5 | GO:0050700 | CARD domain binding(GO:0050700) |
0.1 | 0.4 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.1 | 0.2 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.1 | 0.3 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
0.1 | 0.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 0.2 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.9 | GO:0070628 | proteasome binding(GO:0070628) |
0.1 | 0.3 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) GPI anchor binding(GO:0034235) |
0.1 | 1.0 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 0.1 | GO:0008107 | galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127) |
0.1 | 0.5 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.1 | 1.6 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.1 | 0.8 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
0.1 | 0.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
0.1 | 0.3 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
0.1 | 1.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.1 | 0.4 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
0.1 | 0.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.3 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.1 | 0.4 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.1 | 0.3 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 0.4 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 0.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.1 | 0.3 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.1 | 0.3 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.1 | 2.3 | GO:0002020 | protease binding(GO:0002020) |
0.1 | 0.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 0.5 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
0.1 | 0.3 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
0.1 | 0.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
0.1 | 0.3 | GO:0015056 | corticotrophin-releasing factor receptor activity(GO:0015056) |
0.1 | 1.8 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 0.1 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.0 | 0.2 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.0 | 0.2 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
0.0 | 0.9 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.0 | 0.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.0 | 2.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
0.0 | 0.4 | GO:0048495 | Roundabout binding(GO:0048495) |
0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.1 | GO:0000150 | recombinase activity(GO:0000150) |
0.0 | 0.6 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 1.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.3 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.3 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
0.0 | 0.2 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
0.0 | 0.2 | GO:0048156 | tau protein binding(GO:0048156) |
0.0 | 0.6 | GO:0016891 | endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891) |
0.0 | 0.2 | GO:0003720 | telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964) |
0.0 | 0.2 | GO:0042808 | obsolete neuronal Cdc2-like kinase binding(GO:0042808) |
0.0 | 0.7 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
0.0 | 0.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
0.0 | 0.5 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
0.0 | 0.9 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.0 | 1.6 | GO:0001948 | glycoprotein binding(GO:0001948) |
0.0 | 0.6 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.3 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
0.0 | 1.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
0.0 | 0.1 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.0 | 0.2 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
0.0 | 0.1 | GO:0001228 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
0.0 | 1.4 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
0.0 | 0.2 | GO:0004803 | transposase activity(GO:0004803) |
0.0 | 0.2 | GO:0016520 | growth hormone-releasing hormone receptor activity(GO:0016520) |
0.0 | 0.6 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.2 | GO:0004367 | glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367) |
0.0 | 0.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.3 | GO:0008308 | voltage-gated anion channel activity(GO:0008308) |
0.0 | 0.4 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.0 | 0.4 | GO:0015301 | anion:anion antiporter activity(GO:0015301) |
0.0 | 0.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
0.0 | 0.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
0.0 | 0.1 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
0.0 | 0.2 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
0.0 | 0.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 1.3 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.1 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
0.0 | 0.2 | GO:0019956 | chemokine binding(GO:0019956) |
0.0 | 0.1 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.0 | 0.6 | GO:0043498 | obsolete cell surface binding(GO:0043498) |
0.0 | 0.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.1 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
0.0 | 0.2 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) |
0.0 | 1.0 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.1 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.0 | 1.2 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.0 | 0.7 | GO:0005319 | lipid transporter activity(GO:0005319) |
0.0 | 0.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.1 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.0 | 0.6 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 0.2 | GO:0016594 | glycine binding(GO:0016594) |
0.0 | 0.1 | GO:0004802 | transketolase activity(GO:0004802) |
0.0 | 0.2 | GO:0004103 | choline kinase activity(GO:0004103) |
0.0 | 0.6 | GO:0004540 | ribonuclease activity(GO:0004540) |
0.0 | 0.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
0.0 | 0.1 | GO:0004988 | obsolete mu-opioid receptor activity(GO:0004988) |
0.0 | 0.1 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.0 | 0.1 | GO:0042296 | ISG15 transferase activity(GO:0042296) |
0.0 | 0.3 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.0 | 1.1 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.0 | 2.3 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.2 | GO:0005148 | prolactin receptor binding(GO:0005148) |
0.0 | 0.2 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.2 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 1.2 | GO:0003823 | antigen binding(GO:0003823) |
0.0 | 0.3 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
0.0 | 0.2 | GO:0031996 | thioesterase binding(GO:0031996) |
0.0 | 0.2 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
0.0 | 0.4 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.2 | GO:0003993 | acid phosphatase activity(GO:0003993) |
0.0 | 0.3 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.7 | GO:0003724 | RNA helicase activity(GO:0003724) |
0.0 | 0.2 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
0.0 | 0.6 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
0.0 | 0.2 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
0.0 | 0.2 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.2 | GO:0004954 | prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.0 | 0.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.0 | 0.4 | GO:0004527 | exonuclease activity(GO:0004527) |
0.0 | 0.1 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 0.1 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.0 | 0.3 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.1 | GO:0016801 | hydrolase activity, acting on ether bonds(GO:0016801) |
0.0 | 0.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.1 | GO:0004339 | glucan 1,4-alpha-glucosidase activity(GO:0004339) |
0.0 | 1.1 | GO:0019902 | phosphatase binding(GO:0019902) |
0.0 | 2.9 | GO:0003690 | double-stranded DNA binding(GO:0003690) |
0.0 | 0.1 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.0 | 0.0 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.0 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 0.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.0 | 0.4 | GO:0030528 | obsolete transcription regulator activity(GO:0030528) |
0.0 | 0.5 | GO:0003702 | obsolete RNA polymerase II transcription factor activity(GO:0003702) |
0.0 | 0.1 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.1 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
0.0 | 0.1 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.0 | 0.5 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.1 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.0 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.0 | 0.3 | GO:0017046 | peptide hormone binding(GO:0017046) |
0.0 | 0.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.0 | 0.0 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
0.0 | 0.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.2 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.2 | GO:0005504 | fatty acid binding(GO:0005504) |
0.0 | 0.1 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
0.0 | 0.1 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 3.1 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
0.1 | 0.5 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |
0.1 | 1.6 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.1 | 1.4 | SA_FAS_SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
0.1 | 2.3 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
0.1 | 0.6 | ST_GAQ_PATHWAY | G alpha q Pathway |
0.1 | 3.2 | SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
0.1 | 4.1 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
0.0 | 0.2 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
0.0 | 1.0 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 0.6 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.2 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.5 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.2 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
0.0 | 0.1 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |