Motif ID: TBX20

Z-value: 1.042


Transcription factors associated with TBX20:

Gene SymbolEntrez IDGene Name
TBX20 ENSG00000164532.10 TBX20



Activity profile for motif TBX20.

activity profile for motif TBX20


Sorted Z-values histogram for motif TBX20

Sorted Z-values for motif TBX20



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX20

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_57662419 2.912 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
 GPR56






G protein-coupled receptor 56






chr17_-_7080227 0.989 ENST00000574330.1
 ASGR1
asialoglycoprotein receptor 1
chr10_+_114135004 0.885 ENST00000393081.1
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114135952 0.765 ENST00000356116.1
ENST00000433418.1
ENST00000354273.4
 ACSL5


acyl-CoA synthetase long-chain family member 5


chr3_+_142315225 0.737 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
 PLS1





plastin 1





chrX_+_78200913 0.736 ENST00000171757.2
 P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chrX_+_78200829 0.731 ENST00000544091.1
 P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr2_+_61108650 0.693 ENST00000295025.8
 REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_+_56915668 0.528 ENST00000333201.9
ENST00000391778.3
 ZNF583

zinc finger protein 583

chr19_-_4540486 0.508 ENST00000306390.6
 LRG1
leucine-rich alpha-2-glycoprotein 1
chr2_+_61108771 0.493 ENST00000394479.3
 REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr1_+_162760513 0.457 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
 HSD17B7



hydroxysteroid (17-beta) dehydrogenase 7



chr17_-_3599327 0.457 ENST00000551178.1
ENST00000552276.1
ENST00000547178.1
 P2RX5


purinergic receptor P2X, ligand-gated ion channel, 5


chr3_+_40428647 0.398 ENST00000301825.3
ENST00000439533.1
ENST00000456402.1
 ENTPD3


ectonucleoside triphosphate diphosphohydrolase 3


chr17_-_3599696 0.381 ENST00000225328.5
 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_3599492 0.369 ENST00000435558.1
ENST00000345901.3
 P2RX5

purinergic receptor P2X, ligand-gated ion channel, 5

chr15_-_22448819 0.368 ENST00000604066.1
 IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr8_+_27183033 0.361 ENST00000420218.2
 PTK2B
protein tyrosine kinase 2 beta
chr8_+_27182862 0.355 ENST00000521164.1
ENST00000346049.5
 PTK2B

protein tyrosine kinase 2 beta

chr13_+_113760098 0.348 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
 F7


coagulation factor VII (serum prothrombin conversion accelerator)


chr1_+_43824669 0.344 ENST00000372462.1
 CDC20
cell division cycle 20
chr6_-_136788001 0.323 ENST00000544465.1
 MAP7
microtubule-associated protein 7
chr5_+_133861339 0.289 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
 PHF15


jade family PHD finger 2


chr2_+_173940442 0.261 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
 MLTK


Mitogen-activated protein kinase kinase kinase MLT


chr6_-_84937314 0.258 ENST00000257766.4
ENST00000403245.3
 KIAA1009

KIAA1009

chr12_+_15475331 0.255 ENST00000281171.4
 PTPRO
protein tyrosine phosphatase, receptor type, O
chr2_+_207630081 0.253 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
 FASTKD2



FAST kinase domains 2



chr12_+_15475462 0.253 ENST00000543886.1
ENST00000348962.2
 PTPRO

protein tyrosine phosphatase, receptor type, O

chr9_-_72287191 0.205 ENST00000265381.4
 APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr15_-_74504560 0.202 ENST00000449139.2
 STRA6
stimulated by retinoic acid 6
chr15_-_74504597 0.198 ENST00000416286.3
 STRA6
stimulated by retinoic acid 6
chr2_+_64068074 0.186 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
 UGP2



UDP-glucose pyrophosphorylase 2



chr5_+_161494521 0.184 ENST00000356592.3
 GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr22_-_46283597 0.169 ENST00000451118.1
 WI2-85898F10.1
WI2-85898F10.1
chr14_-_106453155 0.155 ENST00000390594.2
 IGHV1-2
immunoglobulin heavy variable 1-2
chr2_-_219134822 0.152 ENST00000444053.1
ENST00000248450.4
 AAMP

angio-associated, migratory cell protein

chr20_-_48782639 0.151 ENST00000435301.2
 RP11-112L6.3
RP11-112L6.3
chr20_+_44509857 0.139 ENST00000372523.1
ENST00000372520.1
 ZSWIM1

zinc finger, SWIM-type containing 1

chr15_-_38519066 0.126 ENST00000561320.1
ENST00000561161.1
 RP11-346D14.1

RP11-346D14.1

chr6_-_2842219 0.124 ENST00000380739.5
 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_219134343 0.123 ENST00000447885.1
ENST00000420660.1
 AAMP

angio-associated, migratory cell protein

chr4_-_26492076 0.103 ENST00000295589.3
 CCKAR
cholecystokinin A receptor
chr3_-_15140629 0.102 ENST00000507357.1
ENST00000449050.1
ENST00000253699.3
ENST00000435849.3
ENST00000476527.2
 ZFYVE20




zinc finger, FYVE domain containing 20




chr1_+_147013182 0.100 ENST00000234739.3
 BCL9
B-cell CLL/lymphoma 9
chr6_-_2842087 0.100 ENST00000537185.1
 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_121477039 0.082 ENST00000257570.5
 OASL
2'-5'-oligoadenylate synthetase-like
chr11_+_6281036 0.078 ENST00000532715.1
ENST00000525014.1
ENST00000531712.1
ENST00000525462.1
 CCKBR



cholecystokinin B receptor



chr1_-_11865982 0.074 ENST00000418034.1
 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr2_+_176972000 0.070 ENST00000249504.5
 HOXD11
homeobox D11
chr7_-_139763521 0.059 ENST00000263549.3
 PARP12
poly (ADP-ribose) polymerase family, member 12
chr3_-_183273477 0.038 ENST00000341319.3
 KLHL6
kelch-like family member 6
chr1_-_154909329 0.027 ENST00000368467.3
 PMVK
phosphomevalonate kinase
chr1_-_158300747 0.027 ENST00000451207.1
 CD1B
CD1b molecule
chr7_-_142207004 0.025 ENST00000426318.2
 TRBV10-2
T cell receptor beta variable 10-2
chr11_-_89540388 0.022 ENST00000532501.2
 TRIM49
tripartite motif containing 49
chr1_+_11866207 0.018 ENST00000312413.6
ENST00000346436.6
 CLCN6

chloride channel, voltage-sensitive 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.1 1.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.3 GO:0032571 response to vitamin K(GO:0032571)
0.1 1.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.2 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.0 0.7 GO:0014009 glial cell proliferation(GO:0014009)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065)
0.0 2.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 1.0 GO:0031668 cellular response to extracellular stimulus(GO:0031668)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.