Motif ID: TEAD3_TEAD1

Z-value: 6.565

Transcription factors associated with TEAD3_TEAD1:

Gene SymbolEntrez IDGene Name
TEAD1 ENSG00000187079.10 TEAD1
TEAD3 ENSG00000007866.14 TEAD3






Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD3_TEAD1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132272504 48.892 ENST00000367976.3
CTGF
connective tissue growth factor
chr5_-_39425068 33.204 ENST00000515700.1
ENST00000339788.6
DAB2

Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)

chr2_-_161264385 18.939 ENST00000409972.1
RBMS1
RNA binding motif, single stranded interacting protein 1
chr7_+_134464414 18.860 ENST00000361901.2
CALD1
caldesmon 1
chr6_-_128841503 18.550 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr10_-_90712520 17.952 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_86046433 17.717 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_39425222 16.824 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr15_+_39873268 16.636 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr5_-_39425290 16.375 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_-_95391315 16.123 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr7_+_134464376 15.599 ENST00000454108.1
ENST00000361675.2
CALD1

caldesmon 1

chr4_-_187644930 15.496 ENST00000441802.2
FAT1
FAT atypical cadherin 1
chr4_+_184020398 15.274 ENST00000403733.3
ENST00000378925.3
WWC2

WW and C2 domain containing 2

chr15_+_63334831 14.092 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1








tropomyosin 1 (alpha)








chr2_-_216257849 13.739 ENST00000456923.1
FN1
fibronectin 1
chr7_+_134430212 13.521 ENST00000436461.2
CALD1
caldesmon 1
chr16_+_30387141 11.984 ENST00000566955.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr10_-_17659234 11.859 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chrX_-_10588459 11.746 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr3_-_134093275 11.583 ENST00000513145.1
ENST00000422605.2
AMOTL2

angiomotin like 2

chr11_-_111781454 11.578 ENST00000533280.1
CRYAB
crystallin, alpha B
chr7_+_116165754 11.473 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr5_-_55290773 11.012 ENST00000502326.3
ENST00000381298.2
IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

chr3_-_134093395 10.611 ENST00000249883.5
AMOTL2
angiomotin like 2
chr4_+_169552748 10.354 ENST00000504519.1
ENST00000512127.1
PALLD

palladin, cytoskeletal associated protein

chr1_-_1293904 10.100 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8


matrix-remodelling associated 8


chr7_+_116165038 9.932 ENST00000393470.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr1_-_201346761 9.694 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2









troponin T type 2 (cardiac)









chr16_-_122619 9.534 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_-_94050668 8.899 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr10_+_123872483 8.832 ENST00000369001.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr4_-_186733363 8.699 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr11_+_114166536 8.509 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr3_-_114343039 8.466 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_30386098 7.776 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr17_-_40575535 7.672 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr8_+_70378852 7.663 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr11_-_47470591 7.627 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr7_+_128470431 7.479 ENST00000325888.8
ENST00000346177.6
FLNC

filamin C, gamma

chr10_-_99447024 7.377 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr2_-_190044480 7.341 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_47470703 7.264 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr10_-_33247124 7.197 ENST00000414670.1
ENST00000302278.3
ENST00000374956.4
ENST00000488494.1
ENST00000417122.2
ENST00000474568.1
ITGB1





integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)





chr3_-_185538849 7.158 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr20_+_35169885 6.958 ENST00000279022.2
ENST00000346786.2
MYL9

myosin, light chain 9, regulatory

chr11_-_47470682 6.845 ENST00000529341.1
ENST00000352508.3
RAPSN

receptor-associated protein of the synapse

chr2_-_20212422 6.813 ENST00000421259.2
ENST00000407540.3
MATN3

matrilin 3

chr15_+_33010175 6.759 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1


gremlin 1, DAN family BMP antagonist


chr11_-_111781610 6.303 ENST00000525823.1
CRYAB
crystallin, alpha B
chr12_-_8815299 6.250 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr11_-_111782696 6.217 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr1_+_114522049 6.113 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chr12_-_8815215 5.965 ENST00000544889.1
ENST00000543369.1
MFAP5

microfibrillar associated protein 5

chr12_-_7245125 5.923 ENST00000542285.1
ENST00000540610.1
C1R

complement component 1, r subcomponent

chr1_-_16482554 5.796 ENST00000358432.5
EPHA2
EPH receptor A2
chrX_-_6146876 5.530 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr11_-_8832182 5.451 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
ST5



suppression of tumorigenicity 5



chr6_+_30850697 5.298 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1






discoidin domain receptor tyrosine kinase 1






chr12_-_54813229 5.255 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr12_-_8815404 5.199 ENST00000359478.2
ENST00000396549.2
MFAP5

microfibrillar associated protein 5

chr11_-_111781554 5.119 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr11_-_111782484 5.089 ENST00000533971.1
CRYAB
crystallin, alpha B
chrX_-_10851762 5.086 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr3_+_147127142 4.907 ENST00000282928.4
ZIC1
Zic family member 1
chr2_-_192711968 4.718 ENST00000304141.4
SDPR
serum deprivation response
chr15_+_96869165 4.572 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr9_-_13175823 4.513 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr15_-_60690163 4.388 ENST00000558998.1
ENST00000560165.1
ENST00000557986.1
ENST00000559780.1
ENST00000559467.1
ENST00000559956.1
ENST00000332680.4
ENST00000396024.3
ENST00000421017.2
ENST00000560466.1
ENST00000558132.1
ENST00000559113.1
ENST00000557906.1
ENST00000558558.1
ENST00000560468.1
ENST00000559370.1
ENST00000558169.1
ENST00000559725.1
ENST00000558985.1
ENST00000451270.2
ANXA2



















annexin A2



















chr6_+_83072923 4.379 ENST00000535040.1
TPBG
trophoblast glycoprotein
chr21_+_30502806 4.275 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr2_-_211179883 4.230 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr11_-_14379997 4.136 ENST00000526063.1
ENST00000532814.1
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr6_+_83073334 4.127 ENST00000369750.3
TPBG
trophoblast glycoprotein
chr19_-_50143452 4.099 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr19_-_14606900 3.981 ENST00000393029.3
ENST00000393028.1
ENST00000393033.4
ENST00000345425.2
ENST00000586027.1
ENST00000591349.1
ENST00000587210.1
GIPC1






GIPC PDZ domain containing family, member 1






chr19_+_15218180 3.947 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1


synapse defective 1, Rho GTPase, homolog 1 (C. elegans)


chr3_-_127541194 3.924 ENST00000453507.2
MGLL
monoglyceride lipase
chr15_-_48937982 3.845 ENST00000316623.5
FBN1
fibrillin 1
chr15_+_63354769 3.844 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr9_+_131314859 3.749 ENST00000358161.5
ENST00000372731.4
ENST00000372739.3
SPTAN1


spectrin, alpha, non-erythrocytic 1


chr9_-_16727978 3.721 ENST00000418777.1
ENST00000468187.2
BNC2

basonuclin 2

chr13_-_33760216 3.598 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_+_111782934 3.428 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr17_-_39677971 3.387 ENST00000393976.2
KRT15
keratin 15
chr12_-_104443890 3.386 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
GLT8D2


glycosyltransferase 8 domain containing 2


chrX_+_99899180 3.377 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_229569834 3.358 ENST00000366684.3
ENST00000366683.2
ACTA1

actin, alpha 1, skeletal muscle

chr1_-_94079648 3.330 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr18_-_25616519 3.330 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr4_-_186877806 3.309 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_+_41614909 3.218 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1


LIM and calponin homology domains 1


chr9_+_112542591 3.206 ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
ENST00000483909.1
ENST00000314527.4
PALM2-AKAP2

AKAP2

PALM2

PALM2-AKAP2 readthrough

A kinase (PRKA) anchor protein 2

paralemmin 2

chr1_-_201438282 3.197 ENST00000367311.3
ENST00000367309.1
PHLDA3

pleckstrin homology-like domain, family A, member 3

chr19_-_51512804 3.180 ENST00000594211.1
ENST00000376832.4
KLK9

kallikrein-related peptidase 9

chr9_+_139873264 3.158 ENST00000446677.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr9_-_139891165 3.107 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr8_+_1772132 3.047 ENST00000349830.3
ENST00000520359.1
ENST00000518288.1
ENST00000398560.1
ARHGEF10



Rho guanine nucleotide exchange factor (GEF) 10



chr8_+_97597148 3.015 ENST00000521590.1
SDC2
syndecan 2
chr16_+_14802801 3.007 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr4_-_186877502 2.995 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr19_+_39138320 2.929 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4


actinin, alpha 4


chr3_-_149375783 2.837 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1


WW domain containing transcription regulator 1


chr1_+_196621002 2.833 ENST00000367429.4
ENST00000439155.2
CFH

complement factor H

chr6_+_123110302 2.749 ENST00000368440.4
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr5_+_36608422 2.749 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_-_35464727 2.727 ENST00000402886.3
TEAD3
TEA domain family member 3
chr9_+_112542572 2.723 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr8_-_119124045 2.718 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr3_-_52486841 2.708 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr2_+_170366203 2.703 ENST00000284669.1
KLHL41
kelch-like family member 41
chr11_+_101981169 2.698 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1



Yes-associated protein 1



chr11_+_66824276 2.676 ENST00000308831.2
RHOD
ras homolog family member D
chr10_-_92681033 2.676 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_33625154 2.663 ENST00000265371.4
NRP1
neuropilin 1
chr7_-_150946015 2.661 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_217560248 2.642 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr8_-_125740514 2.631 ENST00000325064.5
ENST00000518547.1
MTSS1

metastasis suppressor 1

chr6_+_123110465 2.610 ENST00000539041.1
SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr13_+_32605437 2.574 ENST00000380250.3
FRY
furry homolog (Drosophila)
chrX_-_41449204 2.566 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr9_+_103204553 2.496 ENST00000334943.6
ENST00000502978.1
TMEFF1
MSANTD3-TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
MSANTD3-TMEFF1 readthrough
chr6_-_35464817 2.452 ENST00000338863.7
TEAD3
TEA domain family member 3
chr18_+_7754957 2.432 ENST00000400053.4
PTPRM
protein tyrosine phosphatase, receptor type, M
chr16_-_15474904 2.390 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chr9_-_14314566 2.366 ENST00000397579.2
NFIB
nuclear factor I/B
chr4_-_7873981 2.267 ENST00000360265.4
AFAP1
actin filament associated protein 1
chr9_-_14314518 2.264 ENST00000397581.2
NFIB
nuclear factor I/B
chr10_+_123923205 2.257 ENST00000369004.3
ENST00000260733.3
TACC2

transforming, acidic coiled-coil containing protein 2

chr11_-_64013663 2.251 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr19_+_676385 2.241 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr6_+_148663729 2.204 ENST00000367467.3
SASH1
SAM and SH3 domain containing 1
chr4_-_186732048 2.201 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr5_+_140868717 2.094 ENST00000252087.1
PCDHGC5
protocadherin gamma subfamily C, 5
chr17_+_37856299 2.030 ENST00000269571.5
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr15_+_43809797 1.991 ENST00000399453.1
ENST00000300231.5
MAP1A

microtubule-associated protein 1A

chr11_-_62521614 1.973 ENST00000527994.1
ENST00000394807.3
ZBTB3

zinc finger and BTB domain containing 3

chr17_-_10325261 1.971 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr11_-_76381029 1.968 ENST00000407242.2
ENST00000421973.1
LRRC32

leucine rich repeat containing 32

chr18_+_3247779 1.954 ENST00000578611.1
ENST00000583449.1
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr1_+_196621156 1.947 ENST00000359637.2
CFH
complement factor H
chr8_-_108510224 1.942 ENST00000517746.1
ENST00000297450.3
ANGPT1

angiopoietin 1

chr12_-_8815477 1.928 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr15_+_62853562 1.921 ENST00000561311.1
TLN2
talin 2
chr19_+_39138271 1.762 ENST00000252699.2
ACTN4
actinin, alpha 4
chr18_+_3247413 1.741 ENST00000579226.1
ENST00000217652.3
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr7_+_100464760 1.741 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr8_+_94929969 1.730 ENST00000517764.1
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr15_-_42565606 1.698 ENST00000307216.6
ENST00000448392.1
TMEM87A

transmembrane protein 87A

chr1_-_109935819 1.682 ENST00000538502.1
SORT1
sortilin 1
chrY_+_16634483 1.644 ENST00000382872.1
NLGN4Y
neuroligin 4, Y-linked
chr11_+_66824346 1.613 ENST00000532559.1
RHOD
ras homolog family member D
chr1_-_227506158 1.612 ENST00000366769.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr4_+_166300084 1.594 ENST00000402744.4
CPE
carboxypeptidase E
chrX_-_23761317 1.572 ENST00000492081.1
ENST00000379303.5
ENST00000336430.7
ACOT9


acyl-CoA thioesterase 9


chr14_-_23904861 1.559 ENST00000355349.3
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr2_+_102759199 1.558 ENST00000409288.1
ENST00000410023.1
IL1R1

interleukin 1 receptor, type I

chr6_+_143999072 1.505 ENST00000440869.2
ENST00000367582.3
ENST00000451827.2
PHACTR2


phosphatase and actin regulator 2


chr20_-_14318248 1.493 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr10_-_75410771 1.489 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr13_-_67804445 1.469 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
PCDH9


protocadherin 9


chr17_+_37856253 1.469 ENST00000540147.1
ENST00000584450.1
ERBB2

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

chr7_-_27219849 1.468 ENST00000396344.4
HOXA10
homeobox A10
chr17_-_7297833 1.460 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr1_-_205290865 1.447 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr12_+_3068466 1.437 ENST00000358409.2
TEAD4
TEA domain family member 4
chr17_+_43224684 1.424 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr6_-_3157760 1.423 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr20_+_3451650 1.417 ENST00000262919.5
ATRN
attractin
chr12_-_47219733 1.408 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
SLC38A4


solute carrier family 38, member 4


chr18_+_55862622 1.358 ENST00000456173.2
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr20_+_44044717 1.335 ENST00000279036.6
ENST00000279035.9
ENST00000372689.5
ENST00000545755.1
ENST00000341555.5
ENST00000535404.1
ENST00000543458.2
ENST00000432270.1
PIGT







phosphatidylinositol glycan anchor biosynthesis, class T







chr16_+_1578674 1.310 ENST00000253934.5
TMEM204
transmembrane protein 204
chr14_+_74035763 1.309 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr14_+_32546485 1.304 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5


Rho GTPase activating protein 5


chr12_+_27677085 1.299 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1






PTPRF interacting protein, binding protein 1 (liprin beta 1)






chr6_-_152489484 1.297 ENST00000354674.4
ENST00000539504.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr1_-_209825674 1.296 ENST00000367030.3
ENST00000356082.4
LAMB3

laminin, beta 3

chrX_+_153046456 1.283 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRPK3





SRSF protein kinase 3





chr11_-_64013288 1.274 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_+_46299199 1.241 ENST00000529193.1
ENST00000288400.3
CREB3L1

cAMP responsive element binding protein 3-like 1

chr12_+_3068544 1.219 ENST00000540314.1
ENST00000536826.1
ENST00000359864.2
TEAD4


TEA domain family member 4


chr17_-_79105734 1.213 ENST00000417379.1
AATK
apoptosis-associated tyrosine kinase
chr16_-_21436459 1.201 ENST00000448012.2
ENST00000504841.2
ENST00000419180.2
NPIPB3


nuclear pore complex interacting protein family, member B3


chr17_+_37856214 1.186 ENST00000445658.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr5_-_95158644 1.176 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr6_-_52926539 1.174 ENST00000350082.5
ENST00000356971.3
ICK

intestinal cell (MAK-like) kinase

chr9_-_23826298 1.171 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr16_+_30907927 1.146 ENST00000279804.2
ENST00000395019.3
CTF1

cardiotrophin 1

chr1_+_178310581 1.099 ENST00000462775.1
RASAL2
RAS protein activator like 2
chr11_+_7506713 1.098 ENST00000329293.3
ENST00000534244.1
OLFML1

olfactomedin-like 1

chr12_-_111358372 1.093 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr17_+_7348658 1.082 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
CHRNB1


cholinergic receptor, nicotinic, beta 1 (muscle)


chr15_+_41245160 1.081 ENST00000444189.2
ENST00000446533.3
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr5_-_176923846 1.077 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr3_-_47950745 1.073 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr8_-_38325219 1.066 ENST00000533668.1
ENST00000413133.2
ENST00000397108.4
ENST00000526742.1
ENST00000525001.1
ENST00000425967.3
ENST00000529552.1
ENST00000397113.2
FGFR1







fibroblast growth factor receptor 1







chr5_-_95158375 1.064 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
GLRX



glutaredoxin (thioltransferase)



chr12_-_120687948 1.053 ENST00000458477.2
PXN
paxillin
chr12_+_120933859 1.049 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1


dynein, light chain, LC8-type 1



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
22.1 66.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
9.9 49.3 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
6.2 18.5 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
5.5 16.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
4.3 21.4 GO:0044854 membrane raft assembly(GO:0001765) nitric oxide homeostasis(GO:0033484) negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
4.0 11.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
3.0 17.7 GO:0060710 chorio-allantoic fusion(GO:0060710)
2.4 7.2 GO:0002124 territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625)
2.2 17.9 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
1.9 9.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
1.9 5.8 GO:0014028 notochord formation(GO:0014028) axial mesoderm morphogenesis(GO:0048319)
1.7 6.8 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
1.6 4.7 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.2 4.7 GO:0060209 estrus(GO:0060209)
1.1 4.6 GO:0009956 radial pattern formation(GO:0009956)
1.1 12.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
1.1 4.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
1.0 3.0 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.9 13.7 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.9 2.7 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.9 7.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.8 3.4 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.7 10.7 GO:0035329 hippo signaling(GO:0035329)
0.7 2.7 GO:0031223 auditory behavior(GO:0031223) malate-aspartate shuttle(GO:0043490)
0.7 2.6 GO:0030035 microspike assembly(GO:0030035)
0.7 3.9 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 5.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 3.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.5 1.6 GO:1901142 insulin processing(GO:0030070) insulin metabolic process(GO:1901142)
0.5 2.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.4 2.6 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.4 33.7 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.4 2.4 GO:0010842 retina layer formation(GO:0010842)
0.4 3.6 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4 16.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 1.9 GO:0030210 heparin biosynthetic process(GO:0030210) Tie signaling pathway(GO:0048014)
0.4 2.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.4 1.1 GO:0007538 primary sex determination(GO:0007538)
0.4 3.9 GO:0031641 regulation of myelination(GO:0031641)
0.4 1.1 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mesodermal cell fate specification(GO:0042661) lateral mesoderm development(GO:0048368) lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of mesoderm development(GO:2000380)
0.3 7.3 GO:0030199 collagen fibril organization(GO:0030199)
0.3 1.7 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227)
0.3 18.2 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.3 2.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 94.3 GO:0006936 muscle contraction(GO:0006936)
0.2 3.2 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 4.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.4 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.2 4.9 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.2 3.5 GO:0019220 regulation of phosphate metabolic process(GO:0019220) regulation of phosphorylation(GO:0042325)
0.2 0.4 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2 0.8 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.2 1.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 4.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 4.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 3.0 GO:0031000 response to caffeine(GO:0031000)
0.2 1.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.2 0.2 GO:0014742 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.2 1.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.2 0.5 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.3 GO:0045852 integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726) pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 1.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 1.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 5.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.1 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.2 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.1 1.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.1 16.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.0 GO:0048557 embryonic digestive tract morphogenesis(GO:0048557)
0.1 4.1 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.1 4.1 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 0.8 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.7 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.4 GO:0050686 negative regulation of mRNA splicing, via spliceosome(GO:0048025) negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.9 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 6.9 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.1 4.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.0 GO:0006577 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.1 0.8 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 2.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.3 GO:0060648 nipple development(GO:0060618) mammary gland bud morphogenesis(GO:0060648) mammary gland bud elongation(GO:0060649) nipple morphogenesis(GO:0060658) nipple sheath formation(GO:0060659)
0.1 0.5 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.2 GO:0032506 barrier septum assembly(GO:0000917) cytokinetic process(GO:0032506) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410)
0.1 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 1.4 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 14.3 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.1 9.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.6 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 2.4 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 0.1 GO:0061339 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 1.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 1.5 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 17.4 GO:0006260 DNA replication(GO:0006260)
0.1 1.2 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 2.0 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.1 2.0 GO:0051693 actin filament capping(GO:0051693)
0.1 0.2 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 3.2 GO:0009408 response to heat(GO:0009408)
0.1 0.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.7 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.4 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 6.0 GO:0032259 methylation(GO:0032259)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 3.9 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 9.9 GO:0042493 response to drug(GO:0042493)
0.0 5.1 GO:0034329 cell junction assembly(GO:0034329)
0.0 0.1 GO:0060423 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072) cornea development in camera-type eye(GO:0061303)
0.0 0.2 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.7 GO:0006555 methionine metabolic process(GO:0006555)
0.0 1.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.2 GO:0060537 muscle tissue development(GO:0060537)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.5 GO:0070509 calcium ion import(GO:0070509)
0.0 1.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.4 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.4 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:0007204 positive regulation of cytosolic calcium ion concentration(GO:0007204)
0.0 2.7 GO:0001501 skeletal system development(GO:0001501)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 1.2 GO:0007517 muscle organ development(GO:0007517)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
2.7 29.2 GO:0005577 fibrinogen complex(GO:0005577)
2.4 7.3 GO:0005588 collagen type V trimer(GO:0005588)
1.9 48.9 GO:0005801 cis-Golgi network(GO:0005801)
1.5 17.9 GO:0032059 bleb(GO:0032059)
1.4 22.9 GO:0001527 microfibril(GO:0001527)
1.3 5.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.2 4.7 GO:0043219 lateral loop(GO:0043219)
1.1 31.2 GO:0005859 muscle myosin complex(GO:0005859)
0.8 62.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.8 25.0 GO:0005811 lipid particle(GO:0005811)
0.7 3.3 GO:0016342 fascia adherens(GO:0005916) catenin complex(GO:0016342)
0.6 27.9 GO:0031594 neuromuscular junction(GO:0031594)
0.6 4.7 GO:0031143 pseudopodium(GO:0031143)
0.5 102.9 GO:0030016 myofibril(GO:0030016)
0.5 1.4 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 2.7 GO:0043205 fibril(GO:0043205)
0.3 1.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.3 15.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 2.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2 0.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 4.0 GO:0043198 dendritic shaft(GO:0043198)
0.2 10.9 GO:0001726 ruffle(GO:0001726)
0.2 1.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 2.7 GO:0071564 npBAF complex(GO:0071564)
0.2 13.3 GO:0031256 leading edge membrane(GO:0031256)
0.1 2.0 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 10.7 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 1.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 3.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.5 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 2.9 GO:0016459 myosin complex(GO:0016459)
0.1 1.5 GO:0005902 microvillus(GO:0005902)
0.1 4.6 GO:0030496 midbody(GO:0030496)
0.1 10.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 6.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 3.2 GO:0030427 site of polarized growth(GO:0030427)
0.0 3.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 3.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 1.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0042588 zymogen granule(GO:0042588)
0.0 1.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.6 GO:0045202 synapse(GO:0045202)
0.0 3.4 GO:0005912 adherens junction(GO:0005912)
0.0 40.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.5 GO:0030425 dendrite(GO:0030425)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 13.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 3.9 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 67.8 GO:0001968 fibronectin binding(GO:0001968)
4.1 12.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
2.6 5.3 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
2.6 25.8 GO:0030172 troponin C binding(GO:0030172)
2.4 21.7 GO:0033130 acetylcholine receptor binding(GO:0033130)
2.1 8.5 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
2.1 48.5 GO:0005523 tropomyosin binding(GO:0005523)
1.7 10.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.5 20.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
1.3 34.0 GO:0005212 structural constituent of eye lens(GO:0005212)
1.1 5.5 GO:0042043 neurexin family protein binding(GO:0042043)
1.0 7.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.8 18.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 3.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.8 66.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.8 20.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.7 2.7 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.5 7.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.5 5.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.5 4.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 2.7 GO:0031014 troponin T binding(GO:0031014)
0.4 1.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.4 48.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.4 3.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 1.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 4.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.3 1.7 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 4.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.3 5.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 2.2 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.3 3.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 7.3 GO:0017022 myosin binding(GO:0017022)
0.3 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 2.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314) glutamate binding(GO:0016595)
0.3 17.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 2.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 64.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.2 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.2 7.7 GO:0019843 rRNA binding(GO:0019843)
0.2 2.6 GO:0003785 actin monomer binding(GO:0003785)
0.2 2.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 4.4 GO:0004859 phospholipase inhibitor activity(GO:0004859) phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 0.6 GO:0004769 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) steroid delta-isomerase activity(GO:0004769)
0.2 0.8 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 2.9 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 0.2 GO:0032190 acrosin binding(GO:0032190)
0.2 0.8 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 2.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 5.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.7 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 4.3 GO:0019003 GDP binding(GO:0019003)
0.1 16.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.1 2.9 GO:0045296 cadherin binding(GO:0045296)
0.1 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.1 5.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 2.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.1 GO:0019864 IgG binding(GO:0019864)
0.1 0.7 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 7.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 11.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 4.4 GO:0051015 actin filament binding(GO:0051015)
0.1 1.3 GO:0005521 lamin binding(GO:0005521)
0.1 14.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 9.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 1.1 GO:0042166 acetylcholine binding(GO:0042166)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.1 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.9 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 11.6 GO:0003924 GTPase activity(GO:0003924)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 6.2 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 1.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 6.2 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 5.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 6.1 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 4.2 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 6.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0035004 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 4.1 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.2 26.6 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.3 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.8 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.