Motif ID: TFAP2B

Z-value: 1.714


Transcription factors associated with TFAP2B:

Gene SymbolEntrez IDGene Name
TFAP2B ENSG00000008196.8 TFAP2B



Activity profile for motif TFAP2B.

activity profile for motif TFAP2B


Sorted Z-values histogram for motif TFAP2B

Sorted Z-values for motif TFAP2B



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39677971 2.799 ENST00000393976.2
KRT15
keratin 15
chr12_-_89746173 2.272 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr6_-_138428613 2.108 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr16_+_22825475 2.049 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr15_+_101420028 2.032 ENST00000557963.1
ENST00000346623.6
ALDH1A3

aldehyde dehydrogenase 1 family, member A3

chr16_+_68678892 1.974 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr1_-_153588334 1.812 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr12_+_6308881 1.730 ENST00000382518.1
ENST00000536586.1
CD9

CD9 molecule

chr1_+_152881014 1.536 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr1_+_64059332 1.531 ENST00000540265.1
PGM1
phosphoglucomutase 1
chrX_+_131157322 1.479 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4


Serine/threonine-protein kinase MST4


chrX_+_131157290 1.454 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr16_+_68679193 1.442 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr4_-_84030996 1.375 ENST00000411416.2
PLAC8
placenta-specific 8
chr1_+_169075554 1.341 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_-_11148587 1.280 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2


piezo-type mechanosensitive ion channel component 2


chr1_+_2036149 1.091 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ


protein kinase C, zeta


chr3_+_100211412 1.070 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr1_+_1981890 1.043 ENST00000378567.3
ENST00000468310.1
PRKCZ

protein kinase C, zeta

chr9_-_21974820 1.040 ENST00000579122.1
ENST00000498124.1
CDKN2A

cyclin-dependent kinase inhibitor 2A

chr9_+_112542591 1.026 ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
ENST00000483909.1
ENST00000314527.4
PALM2-AKAP2

AKAP2

PALM2

PALM2-AKAP2 readthrough

A kinase (PRKA) anchor protein 2

paralemmin 2

chr17_+_42429493 1.025 ENST00000586242.1
GRN
granulin
chr20_+_62327996 1.002 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr1_-_20812690 0.979 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_-_19739007 0.977 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
LPAR2


lysophosphatidic acid receptor 2


chr1_+_65613852 0.974 ENST00000327299.7
AK4
adenylate kinase 4
chr6_-_47277634 0.972 ENST00000296861.2
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr12_+_53693466 0.942 ENST00000267103.5
ENST00000548632.1
C12orf10

chromosome 12 open reading frame 10

chr19_-_11689752 0.935 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chr16_-_68269971 0.904 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr12_+_7060432 0.901 ENST00000318974.9
ENST00000456013.1
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr10_+_124134201 0.885 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1



pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1



chr1_+_209929377 0.882 ENST00000400959.3
ENST00000367025.3
TRAF3IP3

TRAF3 interacting protein 3

chr14_+_65171315 0.881 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_10326612 0.880 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM





adrenomedullin





chr3_-_124839648 0.870 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr8_+_123793633 0.859 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr1_+_32042105 0.843 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr8_+_126442563 0.815 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr1_+_32042131 0.807 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr2_-_73511559 0.776 ENST00000521871.1
FBXO41
F-box protein 41
chr1_+_32716840 0.758 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_42921761 0.748 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr2_-_220408430 0.736 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr1_+_40506392 0.735 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1











CAP, adenylate cyclase-associated protein 1 (yeast)











chr2_-_43453734 0.733 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr9_-_21975038 0.730 ENST00000446177.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr2_-_208030647 0.728 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_+_95939638 0.716 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2


diaphanous-related formin 2


chr2_+_234580499 0.715 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr20_+_44746885 0.710 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr12_-_15114603 0.709 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_+_44746939 0.705 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr4_-_169239921 0.704 ENST00000514995.1
ENST00000393743.3
DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr12_-_15114492 0.684 ENST00000541546.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr7_-_86849883 0.681 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr5_-_157002775 0.679 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr2_+_234580525 0.674 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr18_-_19283649 0.663 ENST00000584464.1
ENST00000578270.1
ABHD3

abhydrolase domain containing 3

chr14_+_65171099 0.663 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr19_+_38397839 0.648 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr1_-_75198940 0.641 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr21_-_45078019 0.625 ENST00000542962.1
HSF2BP
heat shock transcription factor 2 binding protein
chr1_+_32716857 0.614 ENST00000482949.1
ENST00000495610.2
LCK

lymphocyte-specific protein tyrosine kinase

chr1_-_75198681 0.611 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
CRYZ



crystallin, zeta (quinone reductase)



chrX_+_78200829 0.601 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr20_-_56285595 0.600 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr1_+_155178518 0.587 ENST00000316721.4
MTX1
metaxin 1
chrX_+_78200913 0.582 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr17_+_47448102 0.582 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr17_-_39942940 0.573 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr7_+_94285637 0.558 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr1_+_209929494 0.555 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr21_-_28217721 0.551 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_25291475 0.549 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr3_-_49459878 0.538 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT


aminomethyltransferase


chr9_-_21975088 0.537 ENST00000304494.5
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_-_147245484 0.536 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr1_-_185286461 0.534 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr1_+_155179012 0.525 ENST00000609421.1
MTX1
metaxin 1
chr3_-_48470838 0.519 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr3_-_49459865 0.517 ENST00000427987.1
AMT
aminomethyltransferase
chr2_-_39347524 0.514 ENST00000395038.2
ENST00000402219.2
SOS1

son of sevenless homolog 1 (Drosophila)

chr17_+_12692774 0.507 ENST00000379672.5
ENST00000340825.3
ARHGAP44

Rho GTPase activating protein 44

chr3_-_52090461 0.504 ENST00000296483.6
ENST00000495880.1
DUSP7

dual specificity phosphatase 7

chr22_-_51017084 0.497 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B


carnitine palmitoyltransferase 1B (muscle)


chr12_-_32908809 0.495 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chr1_+_2398876 0.490 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr7_-_143105941 0.483 ENST00000275815.3
EPHA1
EPH receptor A1
chr5_-_150603679 0.481 ENST00000355417.2
CCDC69
coiled-coil domain containing 69
chr2_-_132249955 0.477 ENST00000309451.6
MZT2A
mitotic spindle organizing protein 2A
chr6_-_41040268 0.477 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
OARD1





O-acyl-ADP-ribose deacylase 1





chr13_-_76056250 0.468 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4



TBC1 domain family, member 4



chr22_-_46933067 0.454 ENST00000262738.3
ENST00000395964.1
CELSR1

cadherin, EGF LAG seven-pass G-type receptor 1

chr1_-_237167718 0.454 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr19_+_36195429 0.452 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr1_+_182992545 0.447 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr19_+_45971246 0.443 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB





FBJ murine osteosarcoma viral oncogene homolog B





chr1_+_153746683 0.441 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr8_-_21988558 0.439 ENST00000312841.8
HR
hair growth associated
chr4_+_78078304 0.435 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr6_+_33589161 0.435 ENST00000605930.1
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chrX_+_9983602 0.434 ENST00000380861.4
WWC3
WWC family member 3
chr2_-_28113965 0.430 ENST00000302188.3
RBKS
ribokinase
chr17_+_1646130 0.426 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2




serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2




chr6_-_41040195 0.421 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
OARD1


O-acyl-ADP-ribose deacylase 1


chr3_+_149530836 0.417 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13


ring finger protein 13


chr11_-_7694684 0.414 ENST00000524790.1
ENST00000299497.9
ENST00000299498.6
CYB5R2


cytochrome b5 reductase 2


chr17_-_66287350 0.414 ENST00000580666.1
ENST00000583477.1
SLC16A6

solute carrier family 16, member 6

chr14_+_72052983 0.413 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr16_+_30960375 0.405 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr19_+_36195467 0.405 ENST00000426659.2
ZBTB32
zinc finger and BTB domain containing 32
chr1_+_40505891 0.402 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
CAP1


CAP, adenylate cyclase-associated protein 1 (yeast)


chr19_-_45926739 0.401 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
ERCC1



excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)



chr11_-_7695437 0.399 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
CYB5R2


cytochrome b5 reductase 2


chr12_+_862089 0.399 ENST00000315939.6
ENST00000537687.1
ENST00000447667.2
WNK1


WNK lysine deficient protein kinase 1


chr5_-_157002749 0.397 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19


ADAM metallopeptidase domain 19


chr20_-_50808236 0.396 ENST00000361387.2
ZFP64
ZFP64 zinc finger protein
chr14_+_23340822 0.395 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr17_-_27405875 0.387 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr19_+_45251804 0.386 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr19_+_1067492 0.381 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr5_+_131409476 0.378 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chrX_-_78622805 0.374 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr1_+_155178481 0.370 ENST00000368376.3
MTX1
metaxin 1
chr20_-_50808290 0.370 ENST00000346617.4
ENST00000371515.4
ENST00000371518.2
ZFP64


ZFP64 zinc finger protein


chr8_-_145018905 0.364 ENST00000398774.2
PLEC
plectin
chr6_-_136871957 0.362 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr17_-_66287257 0.360 ENST00000327268.4
SLC16A6
solute carrier family 16, member 6
chr16_-_10674528 0.359 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr20_+_47538357 0.354 ENST00000371917.4
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr19_+_42724423 0.353 ENST00000301215.3
ENST00000597945.1
ZNF526

zinc finger protein 526

chr19_-_45927097 0.350 ENST00000340192.7
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_+_1067144 0.346 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr19_+_35630022 0.341 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr16_+_19179549 0.339 ENST00000355377.2
ENST00000568115.1
SYT17

synaptotagmin XVII

chr12_-_102224704 0.336 ENST00000299314.7
GNPTAB
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_+_42396574 0.336 ENST00000401738.3
EML4
echinoderm microtubule associated protein like 4
chr8_-_145047688 0.335 ENST00000356346.3
PLEC
plectin
chr3_+_141144954 0.325 ENST00000441582.2
ENST00000321464.5
ZBTB38

zinc finger and BTB domain containing 38

chr2_+_42396472 0.323 ENST00000318522.5
ENST00000402711.2
EML4

echinoderm microtubule associated protein like 4

chr1_+_158969752 0.323 ENST00000566111.1
IFI16
interferon, gamma-inducible protein 16
chr1_-_40782938 0.322 ENST00000372736.3
ENST00000372748.3
COL9A2

collagen, type IX, alpha 2

chr1_+_154377669 0.322 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr17_-_61777459 0.317 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2


LIM domain containing 2


chr17_-_4871085 0.310 ENST00000575142.1
ENST00000206020.3
SPAG7

sperm associated antigen 7

chr13_-_25086879 0.310 ENST00000381989.3
PARP4
poly (ADP-ribose) polymerase family, member 4
chr17_-_8093471 0.308 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr2_+_130939827 0.304 ENST00000409255.1
ENST00000455239.1
MZT2B

mitotic spindle organizing protein 2B

chr19_+_42301079 0.303 ENST00000596544.1
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr17_-_2304365 0.296 ENST00000575394.1
ENST00000174618.4
MNT

MAX network transcriptional repressor

chr19_+_1067271 0.295 ENST00000536472.1
ENST00000590214.1
HMHA1

histocompatibility (minor) HA-1

chr22_-_36018569 0.292 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr19_+_54024251 0.288 ENST00000253144.9
ZNF331
zinc finger protein 331
chr15_-_44955842 0.287 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
SPG11




spastic paraplegia 11 (autosomal recessive)




chr17_+_18163848 0.287 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2





mitochondrial elongation factor 2





chr1_-_21503337 0.284 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr21_-_43786634 0.284 ENST00000291527.2
TFF1
trefoil factor 1
chr19_+_35629702 0.283 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr17_-_40835076 0.283 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr14_+_24458123 0.280 ENST00000545240.1
ENST00000382755.4
DHRS4L2

dehydrogenase/reductase (SDR family) member 4 like 2

chr22_+_42229100 0.276 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chrX_+_95939711 0.275 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr17_-_10101868 0.262 ENST00000432992.2
ENST00000540214.1
GAS7

growth arrest-specific 7

chr13_+_28712614 0.261 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_53449593 0.260 ENST00000375340.6
ENST00000322213.4
SMC1A

structural maintenance of chromosomes 1A

chr15_+_78730622 0.257 ENST00000560440.1
IREB2
iron-responsive element binding protein 2
chr19_+_7710774 0.257 ENST00000602355.1
STXBP2
syntaxin binding protein 2
chr19_-_19774473 0.254 ENST00000357324.6
ATP13A1
ATPase type 13A1
chr17_+_66511540 0.251 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr8_-_2585929 0.250 ENST00000519393.1
ENST00000520842.1
ENST00000520570.1
ENST00000517357.1
ENST00000517984.1
ENST00000523971.1
RP11-134O21.1





RP11-134O21.1





chr7_-_27142290 0.248 ENST00000222718.5
HOXA2
homeobox A2
chr17_+_4613918 0.245 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2






arrestin, beta 2






chrX_+_30671476 0.245 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr3_-_150481164 0.243 ENST00000312960.3
SIAH2
siah E3 ubiquitin protein ligase 2
chr6_-_34664612 0.241 ENST00000374023.3
ENST00000374026.3
C6orf106

chromosome 6 open reading frame 106

chr10_+_103825080 0.240 ENST00000299238.5
HPS6
Hermansky-Pudlak syndrome 6
chr19_-_55866104 0.236 ENST00000326529.4
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr13_-_39612176 0.234 ENST00000352251.3
ENST00000350125.3
PROSER1

proline and serine rich 1

chr14_+_24458021 0.231 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
DHRS4L2


dehydrogenase/reductase (SDR family) member 4 like 2


chr8_-_143867946 0.231 ENST00000301263.4
LY6D
lymphocyte antigen 6 complex, locus D
chr19_+_7459998 0.229 ENST00000319670.9
ENST00000599752.1
ARHGEF18

Rho/Rac guanine nucleotide exchange factor (GEF) 18

chr14_+_24458093 0.225 ENST00000558753.1
ENST00000537912.1
DHRS4L2

dehydrogenase/reductase (SDR family) member 4 like 2

chr4_-_39367949 0.225 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1


replication factor C (activator 1) 1, 145kDa


chr17_+_36861735 0.222 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr13_-_41837620 0.221 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1



mitochondrial translational release factor 1



chr12_-_89919965 0.221 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr21_-_47575481 0.219 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr22_+_31892373 0.218 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
SFI1



Sfi1 homolog, spindle assembly associated (yeast)



chr5_+_156693159 0.212 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr14_+_92980111 0.209 ENST00000216487.7
ENST00000557762.1
RIN3

Ras and Rab interactor 3

chr9_+_35605274 0.209 ENST00000336395.5
TESK1
testis-specific kinase 1
chr12_-_57634475 0.208 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr12_+_19282713 0.207 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
PLEKHA5


pleckstrin homology domain containing, family A member 5


chr9_+_136325089 0.207 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
CACFD1


calcium channel flower domain containing 1


chr1_+_172628154 0.205 ENST00000340030.3
ENST00000367721.2
FASLG

Fas ligand (TNF superfamily, member 6)

chrX_+_21392529 0.203 ENST00000425654.2
ENST00000543067.1
CNKSR2

connector enhancer of kinase suppressor of Ras 2

chr14_+_24422795 0.202 ENST00000313250.5
ENST00000558263.1
ENST00000543741.2
ENST00000421831.1
ENST00000397073.2
ENST00000308178.8
ENST00000382761.3
ENST00000397075.3
ENST00000397074.3
ENST00000559632.1
ENST00000558581.1
DHRS4










dehydrogenase/reductase (SDR family) member 4










chr17_+_40834580 0.200 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr21_+_37692481 0.198 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0035987 endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987)
0.5 2.0 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.4 1.7 GO:0030913 paranodal junction assembly(GO:0030913)
0.4 1.4 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.3 2.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.3 1.5 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.3 0.6 GO:0051892 negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.3 1.8 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.2 0.9 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.9 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.2 1.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.7 GO:0051552 flavone metabolic process(GO:0051552)
0.2 1.9 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 0.4 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 1.5 GO:0010224 response to UV-B(GO:0010224)
0.1 0.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 3.0 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.1 0.4 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 1.1 GO:0006546 glycine catabolic process(GO:0006546)
0.1 0.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.2 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.2 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.5 GO:0045176 apical protein localization(GO:0045176)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.2 GO:0046931 pore complex assembly(GO:0046931)
0.1 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.4 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.3 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.6 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.2 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999)
0.0 0.5 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.2 GO:0045953 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.1 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.6 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.3 GO:0030277 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.3 GO:0050684 regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.2 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 1.2 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0021561 facial nerve development(GO:0021561)
0.0 0.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0014063 regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.9 GO:0034332 adherens junction organization(GO:0034332)
0.0 2.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 2.4 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.5 GO:0035050 embryonic heart tube development(GO:0035050)
0.0 0.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.8 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.2 GO:0007004 telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.5 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 2.4 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 1.2 GO:0043473 pigmentation(GO:0043473)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 1.0 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.8 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.2 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 0.0 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0006310 DNA recombination(GO:0006310)
0.0 0.6 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.4 GO:0043259 laminin-10 complex(GO:0043259)
0.1 1.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 1.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 2.6 GO:0030057 desmosome(GO:0030057)
0.1 0.8 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.8 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 3.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0070820 tertiary granule(GO:0070820)
0.0 0.4 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 2.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.3 GO:0030315 obsolete chromatin remodeling complex(GO:0016585) T-tubule(GO:0030315)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.6 GO:0005814 centriole(GO:0005814)
0.0 1.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.1 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.3 2.3 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.3 1.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.2 0.8 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 2.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.0 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.3 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 2.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.0 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.3 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.5 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.0 1.8 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 1.4 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 2.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 2.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.6 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.2 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.