Motif ID: TFAP2B
Z-value: 1.714
Transcription factors associated with TFAP2B:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
TFAP2B | ENSG00000008196.8 | TFAP2B |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 2.2 | GO:0035987 | endodermal cell fate commitment(GO:0001711) endodermal cell differentiation(GO:0035987) |
0.5 | 2.0 | GO:0002072 | optic cup morphogenesis involved in camera-type eye development(GO:0002072) |
0.4 | 1.7 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.4 | 1.4 | GO:1904037 | positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.3 | 2.3 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
0.3 | 1.5 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
0.3 | 0.6 | GO:0051892 | negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044) |
0.3 | 1.8 | GO:0090025 | regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026) |
0.2 | 0.9 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
0.2 | 0.9 | GO:0006701 | progesterone biosynthetic process(GO:0006701) |
0.2 | 1.4 | GO:0050862 | positive regulation of T cell receptor signaling pathway(GO:0050862) |
0.2 | 1.0 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.2 | 0.7 | GO:0051552 | flavone metabolic process(GO:0051552) |
0.2 | 1.9 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.1 | 0.4 | GO:0050917 | sensory perception of umami taste(GO:0050917) |
0.1 | 1.5 | GO:0010224 | response to UV-B(GO:0010224) |
0.1 | 0.4 | GO:0045082 | positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
0.1 | 3.0 | GO:0050732 | negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) |
0.1 | 0.4 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.1 | 0.8 | GO:0006295 | nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) |
0.1 | 1.1 | GO:0006546 | glycine catabolic process(GO:0006546) |
0.1 | 0.9 | GO:0060325 | face morphogenesis(GO:0060325) |
0.1 | 0.3 | GO:0002384 | hepatic immune response(GO:0002384) |
0.1 | 0.3 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
0.1 | 0.5 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.1 | 0.3 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
0.1 | 0.2 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
0.1 | 0.2 | GO:0097300 | necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300) |
0.1 | 0.8 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
0.1 | 0.5 | GO:0045176 | apical protein localization(GO:0045176) |
0.1 | 0.3 | GO:0010447 | response to acidic pH(GO:0010447) |
0.1 | 0.2 | GO:0035283 | rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) |
0.1 | 0.2 | GO:0046931 | pore complex assembly(GO:0046931) |
0.1 | 0.1 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
0.1 | 0.4 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
0.1 | 0.8 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
0.1 | 0.3 | GO:0032933 | SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.1 | 0.6 | GO:0060347 | heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384) |
0.1 | 0.4 | GO:0051918 | negative regulation of fibrinolysis(GO:0051918) |
0.1 | 0.2 | GO:0001999 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) |
0.0 | 0.5 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
0.0 | 0.2 | GO:0045953 | desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of natural killer cell mediated immunity(GO:0002716) negative regulation of natural killer cell mediated cytotoxicity(GO:0045953) |
0.0 | 0.1 | GO:0021919 | BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919) |
0.0 | 0.4 | GO:0019321 | pentose metabolic process(GO:0019321) |
0.0 | 0.4 | GO:0097061 | dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061) |
0.0 | 0.1 | GO:0090009 | primitive streak formation(GO:0090009) |
0.0 | 0.3 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) |
0.0 | 0.3 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 0.2 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.0 | 0.3 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.0 | 0.6 | GO:1902603 | carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603) |
0.0 | 0.3 | GO:0030277 | epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277) |
0.0 | 0.3 | GO:0046835 | carbohydrate phosphorylation(GO:0046835) |
0.0 | 0.2 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
0.0 | 0.3 | GO:0050684 | regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311) |
0.0 | 0.0 | GO:0031223 | auditory behavior(GO:0031223) |
0.0 | 0.2 | GO:0048147 | negative regulation of fibroblast proliferation(GO:0048147) |
0.0 | 0.1 | GO:0002268 | follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268) |
0.0 | 1.2 | GO:0007190 | activation of adenylate cyclase activity(GO:0007190) |
0.0 | 0.1 | GO:0021561 | facial nerve development(GO:0021561) |
0.0 | 0.1 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
0.0 | 1.4 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.2 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.0 | 0.3 | GO:0007128 | meiotic prophase I(GO:0007128) |
0.0 | 0.1 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.0 | 0.1 | GO:0030812 | negative regulation of nucleotide catabolic process(GO:0030812) |
0.0 | 0.1 | GO:0014063 | regulation of serotonin secretion(GO:0014062) negative regulation of serotonin secretion(GO:0014063) |
0.0 | 0.1 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.0 | 0.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.0 | 0.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.0 | 1.9 | GO:0034332 | adherens junction organization(GO:0034332) |
0.0 | 2.3 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.1 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) |
0.0 | 2.4 | GO:0006921 | cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194) |
0.0 | 0.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.4 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
0.0 | 0.2 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
0.0 | 0.5 | GO:0035050 | embryonic heart tube development(GO:0035050) |
0.0 | 0.9 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 0.8 | GO:0048477 | oogenesis(GO:0048477) |
0.0 | 0.2 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
0.0 | 0.2 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
0.0 | 0.2 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.0 | 0.5 | GO:0071804 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
0.0 | 0.0 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
0.0 | 0.6 | GO:0050772 | positive regulation of axonogenesis(GO:0050772) |
0.0 | 0.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 0.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.0 | 2.4 | GO:0006813 | potassium ion transport(GO:0006813) |
0.0 | 0.1 | GO:1901985 | positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
0.0 | 1.2 | GO:0043473 | pigmentation(GO:0043473) |
0.0 | 0.4 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 1.0 | GO:0007623 | circadian rhythm(GO:0007623) |
0.0 | 0.3 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.0 | 0.1 | GO:0033197 | response to vitamin E(GO:0033197) |
0.0 | 0.2 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
0.0 | 1.5 | GO:0016197 | endosomal transport(GO:0016197) |
0.0 | 0.7 | GO:0016126 | sterol biosynthetic process(GO:0016126) |
0.0 | 0.8 | GO:0007162 | negative regulation of cell adhesion(GO:0007162) |
0.0 | 0.6 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
0.0 | 0.5 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.1 | GO:0045749 | obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749) |
0.0 | 0.2 | GO:0010629 | negative regulation of gene expression(GO:0010629) |
0.0 | 0.0 | GO:0044380 | protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698) |
0.0 | 0.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
0.0 | 0.1 | GO:0001954 | positive regulation of cell-matrix adhesion(GO:0001954) |
0.0 | 0.1 | GO:0006310 | DNA recombination(GO:0006310) |
0.0 | 0.6 | GO:0006821 | chloride transport(GO:0006821) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
0.1 | 0.4 | GO:0043259 | laminin-10 complex(GO:0043259) |
0.1 | 1.4 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.1 | 1.3 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 1.7 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 2.6 | GO:0030057 | desmosome(GO:0030057) |
0.1 | 0.8 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
0.1 | 1.5 | GO:0001533 | cornified envelope(GO:0001533) |
0.1 | 0.3 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.1 | 1.1 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 0.8 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.1 | 0.3 | GO:0005594 | collagen type IX trimer(GO:0005594) |
0.1 | 3.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 0.1 | GO:0005900 | oncostatin-M receptor complex(GO:0005900) |
0.0 | 0.3 | GO:0070820 | tertiary granule(GO:0070820) |
0.0 | 0.4 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.0 | 0.3 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
0.0 | 0.5 | GO:0032587 | ruffle membrane(GO:0032587) |
0.0 | 0.2 | GO:0033270 | paranode region of axon(GO:0033270) |
0.0 | 0.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
0.0 | 0.2 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.0 | 0.1 | GO:0005686 | U2 snRNP(GO:0005686) |
0.0 | 0.3 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.2 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
0.0 | 2.4 | GO:0005882 | intermediate filament(GO:0005882) |
0.0 | 0.8 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.1 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
0.0 | 0.9 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.0 | 0.3 | GO:0030315 | obsolete chromatin remodeling complex(GO:0016585) T-tubule(GO:0030315) |
0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.4 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.0 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.6 | GO:0005814 | centriole(GO:0005814) |
0.0 | 1.9 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 2.1 | GO:0005911 | cell-cell junction(GO:0005911) |
0.0 | 0.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.0 | 0.2 | GO:0005796 | Golgi lumen(GO:0005796) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.0 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.5 | 1.4 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.3 | 2.3 | GO:0055105 | ubiquitin-protein transferase inhibitor activity(GO:0055105) |
0.3 | 1.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.2 | 0.7 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.2 | 1.3 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
0.2 | 0.8 | GO:0055103 | ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106) |
0.2 | 2.8 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.1 | 2.0 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
0.1 | 0.4 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
0.1 | 1.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.1 | 1.1 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
0.1 | 1.5 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.1 | 0.4 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
0.1 | 0.3 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
0.1 | 0.5 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.1 | 2.1 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.1 | 0.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.1 | 1.3 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
0.1 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.1 | 1.0 | GO:0008199 | ferric iron binding(GO:0008199) |
0.1 | 0.3 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
0.1 | 1.0 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.1 | 0.8 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.1 | 0.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
0.1 | 0.5 | GO:0042153 | obsolete RPTP-like protein binding(GO:0042153) |
0.1 | 0.8 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.1 | 0.2 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
0.0 | 1.2 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.0 | 0.3 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.0 | 0.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 1.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.0 | 0.2 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
0.0 | 0.4 | GO:0030528 | obsolete transcription regulator activity(GO:0030528) |
0.0 | 0.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.0 | GO:0033549 | MAP kinase phosphatase activity(GO:0033549) |
0.0 | 0.3 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.0 | 0.2 | GO:0017163 | obsolete basal transcription repressor activity(GO:0017163) |
0.0 | 1.8 | GO:0042379 | chemokine receptor binding(GO:0042379) |
0.0 | 0.1 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
0.0 | 0.1 | GO:0030350 | iron-responsive element binding(GO:0030350) |
0.0 | 0.2 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
0.0 | 1.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.0 | 0.1 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 0.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
0.0 | 0.2 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.4 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 2.3 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.1 | GO:0045545 | syndecan binding(GO:0045545) |
0.0 | 0.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.4 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 0.1 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
0.0 | 0.2 | GO:0031701 | angiotensin receptor binding(GO:0031701) |
0.0 | 0.1 | GO:0004339 | glucan 1,4-alpha-glucosidase activity(GO:0004339) |
0.0 | 0.1 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
0.0 | 2.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.3 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.6 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
0.0 | 0.3 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.0 | 0.7 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.0 | 1.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.1 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.1 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 2.5 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.1 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.0 | 0.3 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
0.0 | 0.2 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.1 | GO:0035240 | dopamine binding(GO:0035240) |
0.0 | 0.1 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.4 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 2.5 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 1.6 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 0.3 | ST_STAT3_PATHWAY | STAT3 Pathway |
0.0 | 0.4 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.5 | ST_GAQ_PATHWAY | G alpha q Pathway |
0.0 | 0.2 | SA_G1_AND_S_PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |