Motif ID: TFCP2
Z-value: 1.338
Transcription factors associated with TFCP2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| TFCP2 | ENSG00000135457.5 | TFCP2 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.3 | 1.4 | GO:0010193 | response to ozone(GO:0010193) |
| 0.2 | 1.1 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.2 | 4.3 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
| 0.2 | 1.0 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.2 | 0.5 | GO:0009202 | purine deoxyribonucleotide biosynthetic process(GO:0009153) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) |
| 0.2 | 0.6 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.1 | 0.7 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.1 | 0.6 | GO:0015827 | tryptophan transport(GO:0015827) leucine import(GO:0060356) |
| 0.1 | 1.1 | GO:0036336 | dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336) |
| 0.1 | 0.6 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.1 | 0.5 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.1 | 0.4 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.1 | 1.2 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.1 | 0.4 | GO:0002220 | innate immune response activating cell surface receptor signaling pathway(GO:0002220) |
| 0.1 | 0.3 | GO:0034723 | DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.9 | GO:1901798 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798) |
| 0.1 | 0.2 | GO:0010273 | detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169) |
| 0.1 | 0.4 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.1 | 0.4 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
| 0.1 | 1.1 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
| 0.1 | 0.2 | GO:0051255 | spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) |
| 0.1 | 0.3 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
| 0.1 | 0.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.1 | 1.1 | GO:0032400 | melanosome localization(GO:0032400) |
| 0.1 | 0.4 | GO:0015853 | adenine transport(GO:0015853) |
| 0.1 | 0.3 | GO:0035444 | nickel cation transport(GO:0015675) vanadium ion transport(GO:0015676) ferrous iron transport(GO:0015684) lead ion transport(GO:0015692) nickel cation transmembrane transport(GO:0035444) ferrous iron import(GO:0070627) iron ion import(GO:0097286) |
| 0.1 | 0.5 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.6 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.3 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 0.4 | GO:0010799 | regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.1 | GO:0060267 | respiratory burst involved in defense response(GO:0002679) lipopolysaccharide transport(GO:0015920) positive regulation of respiratory burst(GO:0060267) |
| 0.0 | 0.2 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.0 | 0.2 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.0 | 0.5 | GO:0007035 | vacuolar acidification(GO:0007035) |
| 0.0 | 0.2 | GO:0045003 | DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
| 0.0 | 0.7 | GO:0006911 | phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324) |
| 0.0 | 0.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.0 | 0.9 | GO:0006693 | prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.1 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.0 | 1.1 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 0.2 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905) |
| 0.0 | 0.2 | GO:0007080 | mitotic metaphase plate congression(GO:0007080) |
| 0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.0 | 0.2 | GO:0042640 | anagen(GO:0042640) |
| 0.0 | 0.1 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
| 0.0 | 0.1 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.0 | 0.2 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.4 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.5 | GO:1902583 | multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583) |
| 0.0 | 1.4 | GO:0006821 | chloride transport(GO:0006821) |
| 0.0 | 0.1 | GO:1901998 | tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998) |
| 0.0 | 0.1 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.1 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 1.6 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 0.1 | GO:0070857 | regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
| 0.0 | 0.5 | GO:0006490 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
| 0.0 | 0.3 | GO:0006111 | regulation of gluconeogenesis(GO:0006111) |
| 0.0 | 0.0 | GO:0015855 | pyrimidine nucleobase transport(GO:0015855) |
| 0.0 | 1.7 | GO:0001890 | placenta development(GO:0001890) |
| 0.0 | 0.3 | GO:0045987 | positive regulation of smooth muscle contraction(GO:0045987) |
| 0.0 | 0.3 | GO:0071230 | positive regulation of TOR signaling(GO:0032008) cellular response to amino acid stimulus(GO:0071230) |
| 0.0 | 0.0 | GO:0002887 | positive regulation of cellular extravasation(GO:0002693) negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) |
| 0.0 | 0.1 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.0 | 0.1 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.2 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.0 | 0.1 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.0 | 0.1 | GO:0045059 | positive thymic T cell selection(GO:0045059) |
| 0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.4 | GO:0001937 | negative regulation of endothelial cell proliferation(GO:0001937) |
| 0.0 | 0.1 | GO:0016198 | axon choice point recognition(GO:0016198) |
| 0.0 | 0.3 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
| 0.0 | 0.9 | GO:0010827 | regulation of glucose transport(GO:0010827) |
| 0.0 | 0.5 | GO:0051084 | 'de novo' posttranslational protein folding(GO:0051084) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
| 0.1 | 1.7 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.1 | 0.2 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.1 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 0.4 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.1 | 0.6 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.2 | GO:0005712 | chiasma(GO:0005712) MutLbeta complex(GO:0032390) |
| 0.1 | 1.4 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.7 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.0 | 0.2 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 1.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.5 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.5 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.0 | 0.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.3 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.0 | 0.1 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.0 | 0.1 | GO:0001741 | XY body(GO:0001741) |
| 0.0 | 0.4 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 0.4 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 1.2 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.2 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.6 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.4 | GO:0090568 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568) |
| 0.0 | 0.1 | GO:0005678 | obsolete chromatin assembly complex(GO:0005678) |
| 0.0 | 0.3 | GO:0005640 | nuclear outer membrane(GO:0005640) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 4.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.6 | 2.3 | GO:0001512 | dihydronicotinamide riboside quinone reductase activity(GO:0001512) |
| 0.4 | 1.2 | GO:0047042 | androsterone dehydrogenase (B-specific) activity(GO:0047042) indanol dehydrogenase activity(GO:0047718) |
| 0.4 | 1.4 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.3 | 0.9 | GO:0047026 | androsterone dehydrogenase (A-specific) activity(GO:0047026) |
| 0.2 | 0.5 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 0.2 | 1.3 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
| 0.2 | 0.8 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 1.7 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 1.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.4 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.1 | 1.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.6 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.1 | 0.4 | GO:0046703 | beta-2-microglobulin binding(GO:0030881) natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.6 | GO:0008649 | rRNA methyltransferase activity(GO:0008649) |
| 0.1 | 0.2 | GO:0004960 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 0.1 | 0.7 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 0.4 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 0.2 | GO:0042806 | fucose binding(GO:0042806) |
| 0.1 | 0.6 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 0.3 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.1 | 0.4 | GO:0016151 | nickel cation binding(GO:0016151) |
| 0.1 | 0.4 | GO:0055105 | ubiquitin-protein transferase inhibitor activity(GO:0055105) |
| 0.1 | 0.2 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939) |
| 0.1 | 0.4 | GO:0005345 | purine nucleobase transmembrane transporter activity(GO:0005345) |
| 0.1 | 0.2 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 0.1 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.0 | 0.2 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
| 0.0 | 0.4 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 0.4 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.0 | 0.2 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
| 0.0 | 1.1 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
| 0.0 | 1.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.5 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.6 | GO:0043498 | obsolete cell surface binding(GO:0043498) |
| 0.0 | 0.1 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.0 | 0.5 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.1 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.0 | 0.2 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.0 | 0.1 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.0 | 0.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.1 | GO:0008493 | tetracycline transporter activity(GO:0008493) |
| 0.0 | 0.3 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.2 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
| 0.0 | 0.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 0.5 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.2 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.0 | 0.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.0 | 0.0 | GO:0004947 | bradykinin receptor activity(GO:0004947) |
| 0.0 | 1.6 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.1 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.0 | 0.1 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.1 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 0.2 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.1 | GO:0032405 | MutLalpha complex binding(GO:0032405) |
| 0.0 | 0.1 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.1 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.0 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.1 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.6 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
