Motif ID: TFEC_MITF_ARNTL_BHLHE41

Z-value: 1.179

Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41:

Gene SymbolEntrez IDGene Name
ARNTL ENSG00000133794.13 ARNTL
BHLHE41 ENSG00000123095.5 BHLHE41
MITF ENSG00000187098.10 MITF
TFEC ENSG00000105967.11 TFEC



Activity profile for motif TFEC_MITF_ARNTL_BHLHE41.

activity profile for motif TFEC_MITF_ARNTL_BHLHE41


Sorted Z-values histogram for motif TFEC_MITF_ARNTL_BHLHE41

Sorted Z-values for motif TFEC_MITF_ARNTL_BHLHE41



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_34675391 4.425 ENST00000275954.3
 TMEM47
transmembrane protein 47
chr13_+_113951607 4.199 ENST00000397181.3
 LAMP1
lysosomal-associated membrane protein 1
chr13_+_113951532 4.017 ENST00000332556.4
 LAMP1
lysosomal-associated membrane protein 1
chr6_+_151646800 3.191 ENST00000354675.6
 AKAP12
A kinase (PRKA) anchor protein 12
chrX_-_100914781 3.073 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
 ARMCX2





armadillo repeat containing, X-linked 2





chr3_-_49395705 2.450 ENST00000419349.1
 GPX1
glutathione peroxidase 1
chr3_-_49395892 2.414 ENST00000419783.1
 GPX1
glutathione peroxidase 1
chrX_+_102631844 2.369 ENST00000372634.1
ENST00000299872.7
 NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chrX_+_102631248 2.323 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1


nerve growth factor receptor (TNFRSF16) associated protein 1


chr9_-_79307096 2.308 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
 PRUNE2


prune homolog 2 (Drosophila)


chr19_+_49458107 2.166 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
 BAX






BCL2-associated X protein






chr3_+_112280857 2.135 ENST00000492406.1
ENST00000468642.1
 SLC35A5

solute carrier family 35, member A5

chr12_+_56110247 1.989 ENST00000551926.1
 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr8_-_126104055 1.867 ENST00000318410.7
 KIAA0196
KIAA0196
chr8_-_126103969 1.852 ENST00000517845.1
 KIAA0196
KIAA0196
chr19_-_48018203 1.845 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA


N-ethylmaleimide-sensitive factor attachment protein, alpha


chr1_-_183604794 1.820 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
 ARPC5


actin related protein 2/3 complex, subunit 5, 16kDa


chr17_-_46688334 1.776 ENST00000239165.7
 HOXB7
homeobox B7
chr1_-_155211017 1.772 ENST00000536770.1
ENST00000368373.3
 GBA

glucosidase, beta, acid

chr12_+_81110684 1.750 ENST00000228644.3
 MYF5
myogenic factor 5
chr12_+_56109810 1.742 ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
ENST00000550412.1
 BLOC1S1


RP11-644F5.10
biogenesis of lysosomal organelles complex-1, subunit 1


Uncharacterized protein
chr7_-_27205136 1.740 ENST00000396345.1
ENST00000343483.6
 HOXA9

homeobox A9

chr12_+_56109926 1.736 ENST00000547076.1
 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr1_-_155211065 1.582 ENST00000427500.3
 GBA
glucosidase, beta, acid
chr1_-_68698222 1.578 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
 WLS



wntless Wnt ligand secretion mediator



chr22_+_31002779 1.535 ENST00000215838.3
 TCN2
transcobalamin II
chr1_+_183605200 1.493 ENST00000304685.4
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_47465666 1.489 ENST00000381571.4
 COMMD8
COMM domain containing 8
chr18_+_56530794 1.407 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
 ZNF532


zinc finger protein 532


chr7_+_100464760 1.382 ENST00000200457.4
 TRIP6
thyroid hormone receptor interactor 6
chrX_+_100663243 1.333 ENST00000316594.5
 HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr12_-_110434183 1.321 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
 GIT2





G protein-coupled receptor kinase interacting ArfGAP 2





chr4_+_56719782 1.289 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
 EXOC1


exocyst complex component 1


chr8_+_133787586 1.273 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
 PHF20L1


PHD finger protein 20-like 1


chr22_+_31003133 1.190 ENST00000405742.3
 TCN2
transcobalamin II
chr12_-_110434021 1.178 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
 GIT2


G protein-coupled receptor kinase interacting ArfGAP 2


chr6_+_151561506 1.173 ENST00000253332.1
 AKAP12
A kinase (PRKA) anchor protein 12
chr10_+_46222648 1.160 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
 FAM21C





family with sequence similarity 21, member C





chr6_+_151561085 1.153 ENST00000402676.2
 AKAP12
A kinase (PRKA) anchor protein 12
chr5_+_34656331 1.150 ENST00000265109.3
 RAI14
retinoic acid induced 14
chr5_+_34656569 1.150 ENST00000428746.2
 RAI14
retinoic acid induced 14
chrX_-_100872911 1.147 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6


armadillo repeat containing, X-linked 6


chr16_+_31044812 1.125 ENST00000313843.3
 STX4
syntaxin 4
chr3_-_127541679 1.106 ENST00000265052.5
 MGLL
monoglyceride lipase
chr15_+_44084040 1.091 ENST00000249786.4
 SERF2
small EDRK-rich factor 2
chr18_+_9708162 1.081 ENST00000578921.1
 RAB31
RAB31, member RAS oncogene family
chr1_-_154531095 1.079 ENST00000292211.4
 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr3_+_158519654 1.040 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1


major facilitator superfamily domain containing 1


chr11_-_85779971 1.035 ENST00000393346.3
 PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_+_13049413 1.023 ENST00000316448.5
ENST00000588454.1
 CALR

calreticulin

chr16_-_67514982 0.984 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1


ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1


chr15_-_73925651 0.982 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
 NPTN


neuroplastin


chr8_-_54755459 0.965 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
 ATP6V1H


ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H


chr11_+_18344106 0.913 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
 GTF2H1


general transcription factor IIH, polypeptide 1, 62kDa


chr12_-_65153175 0.908 ENST00000543646.1
ENST00000542058.1
ENST00000258145.3
 GNS


glucosamine (N-acetyl)-6-sulfatase


chr14_-_68283291 0.902 ENST00000555452.1
ENST00000347230.4
 ZFYVE26

zinc finger, FYVE domain containing 26

chr11_+_18343800 0.888 ENST00000453096.2
 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr18_-_21977748 0.884 ENST00000399441.4
ENST00000319481.3
 OSBPL1A

oxysterol binding protein-like 1A

chr7_-_27196267 0.880 ENST00000242159.3
 HOXA7
homeobox A7
chr16_+_31044413 0.868 ENST00000394998.1
 STX4
syntaxin 4
chr14_-_67826486 0.849 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
 ATP6V1D


ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D


chrX_+_100878079 0.847 ENST00000471229.2
 ARMCX3
armadillo repeat containing, X-linked 3
chr10_+_99258625 0.844 ENST00000370664.3
 UBTD1
ubiquitin domain containing 1
chr4_-_76439483 0.829 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
 RCHY1


ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase


chr8_-_82395461 0.828 ENST00000256104.4
 FABP4
fatty acid binding protein 4, adipocyte
chr12_+_56110315 0.823 ENST00000548556.1
 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr7_-_27135591 0.806 ENST00000343060.4
ENST00000355633.5
 HOXA1

homeobox A1

chrX_+_102883887 0.795 ENST00000372625.3
ENST00000372624.3
 TCEAL1

transcription elongation factor A (SII)-like 1

chr1_-_31845914 0.795 ENST00000373713.2
 FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr17_+_42422637 0.793 ENST00000053867.3
ENST00000588143.1
 GRN

granulin

chr1_-_153508460 0.781 ENST00000462776.2
 S100A6
S100 calcium binding protein A6
chr1_-_201476274 0.781 ENST00000340006.2
 CSRP1
cysteine and glycine-rich protein 1
chr14_-_88459503 0.781 ENST00000393568.4
ENST00000261304.2
 GALC

galactosylceramidase

chr19_+_40854559 0.780 ENST00000598962.1
ENST00000409419.1
ENST00000409587.1
ENST00000602131.1
ENST00000409735.4
ENST00000600948.1
ENST00000356508.5
ENST00000596682.1
ENST00000594908.1
 PLD3








phospholipase D family, member 3








chrX_+_102840408 0.776 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
 TCEAL4








transcription elongation factor A (SII)-like 4








chr6_-_80657292 0.770 ENST00000369816.4
 ELOVL4
ELOVL fatty acid elongase 4
chr14_-_81687575 0.764 ENST00000434192.2
 GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr16_-_88923285 0.762 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
 GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chrX_+_102611373 0.745 ENST00000372661.3
ENST00000372656.3
 WBP5

WW domain binding protein 5

chr4_-_76439596 0.738 ENST00000451788.1
ENST00000512706.1
 RCHY1

ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

chrX_+_135229731 0.736 ENST00000420362.1
 FHL1
four and a half LIM domains 1
chr5_-_121413974 0.732 ENST00000231004.4
 LOX
lysyl oxidase
chr15_+_44084503 0.711 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
 SERF2







small EDRK-rich factor 2







chr17_+_42422662 0.708 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
 GRN






granulin






chr3_-_112280709 0.706 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
 ATG3


autophagy related 3


chrX_+_55744166 0.704 ENST00000374941.4
ENST00000414239.1
 RRAGB

Ras-related GTP binding B

chr1_+_145611010 0.703 ENST00000369291.5
 RNF115
ring finger protein 115
chrX_+_55744228 0.696 ENST00000262850.7
 RRAGB
Ras-related GTP binding B
chr8_+_94929168 0.688 ENST00000518107.1
ENST00000396200.3
 PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr19_-_12886327 0.681 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
 HOOK2


hook microtubule-tethering protein 2


chr8_+_94929077 0.681 ENST00000297598.4
ENST00000520614.1
 PDP1

pyruvate dehyrogenase phosphatase catalytic subunit 1

chr1_-_68698197 0.681 ENST00000370973.2
ENST00000370971.1
 WLS

wntless Wnt ligand secretion mediator

chr5_-_172198190 0.676 ENST00000239223.3
 DUSP1
dual specificity phosphatase 1
chr10_-_126716459 0.671 ENST00000309035.6
 CTBP2
C-terminal binding protein 2
chr1_+_221051699 0.663 ENST00000366903.6
 HLX
H2.0-like homeobox
chr1_-_241520525 0.658 ENST00000366565.1
 RGS7
regulator of G-protein signaling 7
chr14_-_54955721 0.646 ENST00000554908.1
 GMFB
glia maturation factor, beta
chr11_-_85779786 0.646 ENST00000356360.5
 PICALM
phosphatidylinositol binding clathrin assembly protein
chr4_+_39184024 0.644 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
 WDR19




WD repeat domain 19




chr22_+_31003190 0.639 ENST00000407817.3
 TCN2
transcobalamin II
chrX_+_100805496 0.633 ENST00000372829.3
 ARMCX1
armadillo repeat containing, X-linked 1
chr12_+_6309517 0.632 ENST00000382519.4
ENST00000009180.4
 CD9

CD9 molecule

chr1_+_154193325 0.627 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
 UBAP2L





ubiquitin associated protein 2-like





chrX_-_15872914 0.626 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
 AP1S2



adaptor-related protein complex 1, sigma 2 subunit



chr19_+_11546153 0.624 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
 PRKCSH


protein kinase C substrate 80K-H


chr17_-_57184064 0.616 ENST00000262294.7
 TRIM37
tripartite motif containing 37
chrY_+_2709527 0.615 ENST00000250784.8
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr8_-_54755789 0.607 ENST00000359530.2
 ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr8_+_94929110 0.604 ENST00000520728.1
 PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_241520385 0.604 ENST00000366564.1
 RGS7
regulator of G-protein signaling 7
chr12_-_21810726 0.604 ENST00000396076.1
 LDHB
lactate dehydrogenase B
chr11_-_2906979 0.603 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
 CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr19_+_12848299 0.601 ENST00000357332.3
 ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr12_-_90102594 0.598 ENST00000428670.3
 ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr5_+_110074685 0.593 ENST00000355943.3
ENST00000447245.2
 SLC25A46

solute carrier family 25, member 46

chr16_+_19567016 0.588 ENST00000251143.5
ENST00000417362.2
ENST00000567245.1
ENST00000513947.4
 C16orf62



chromosome 16 open reading frame 62



chr12_-_21810765 0.585 ENST00000450584.1
ENST00000350669.1
 LDHB

lactate dehydrogenase B

chr2_-_133427767 0.580 ENST00000397463.2
 LYPD1
LY6/PLAUR domain containing 1
chr9_+_103235365 0.574 ENST00000374879.4
 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_+_11546093 0.571 ENST00000591462.1
 PRKCSH
protein kinase C substrate 80K-H
chr1_+_42921761 0.567 ENST00000372562.1
 PPCS
phosphopantothenoylcysteine synthetase
chr3_+_147127142 0.564 ENST00000282928.4
 ZIC1
Zic family member 1
chr19_+_11546440 0.561 ENST00000589126.1
ENST00000588269.1
ENST00000587509.1
ENST00000592741.1
ENST00000593101.1
ENST00000587327.1
 PRKCSH





protein kinase C substrate 80K-H





chr12_+_14518598 0.559 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
 ATF7IP




activating transcription factor 7 interacting protein




chr9_-_131709858 0.555 ENST00000372586.3
 DOLK
dolichol kinase
chr12_+_53645870 0.552 ENST00000329548.4
 MFSD5
major facilitator superfamily domain containing 5
chrY_+_22918021 0.551 ENST00000288666.5
 RPS4Y2
ribosomal protein S4, Y-linked 2
chr7_-_42951509 0.551 ENST00000438029.1
ENST00000432637.1
ENST00000447342.1
ENST00000431882.2
ENST00000350427.4
ENST00000425683.1
 C7orf25





chromosome 7 open reading frame 25





chr12_+_51632508 0.546 ENST00000449723.3
 DAZAP2
DAZ associated protein 2
chr7_-_30029574 0.541 ENST00000426154.1
ENST00000421434.1
ENST00000434476.2
 SCRN1


secernin 1


chr3_+_51428704 0.527 ENST00000323686.4
 RBM15B
RNA binding motif protein 15B
chrY_+_2709906 0.526 ENST00000430575.1
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr7_-_30029367 0.524 ENST00000242059.5
 SCRN1
secernin 1
chr5_+_148521381 0.519 ENST00000504238.1
 ABLIM3
actin binding LIM protein family, member 3
chr12_-_56123444 0.516 ENST00000546457.1
ENST00000549117.1
 CD63

CD63 molecule

chr20_+_56884752 0.512 ENST00000244040.3
 RAB22A
RAB22A, member RAS oncogene family
chrX_+_101975643 0.510 ENST00000361229.4
 BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr12_-_56122761 0.510 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
 CD63


CD63 molecule


chrX_+_102469997 0.509 ENST00000372695.5
ENST00000372691.3
 BEX4

brain expressed, X-linked 4

chr14_+_105941118 0.508 ENST00000550577.1
ENST00000538259.2
 CRIP2

cysteine-rich protein 2

chr15_-_40213080 0.503 ENST00000561100.1
 GPR176
G protein-coupled receptor 176
chr12_+_51632600 0.500 ENST00000549555.1
ENST00000439799.2
ENST00000425012.2
 DAZAP2


DAZ associated protein 2


chr20_+_17550691 0.499 ENST00000474024.1
 DSTN
destrin (actin depolymerizing factor)
chr17_-_57184260 0.496 ENST00000376149.3
ENST00000393066.3
 TRIM37

tripartite motif containing 37

chrX_+_101975619 0.496 ENST00000457056.1
 BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr2_+_242254679 0.489 ENST00000428282.1
ENST00000360051.3
 SEPT2

septin 2

chr3_-_69062764 0.489 ENST00000295571.5
 EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chrX_+_102883620 0.488 ENST00000372626.3
 TCEAL1
transcription elongation factor A (SII)-like 1
chr12_+_51632638 0.475 ENST00000549732.2
 DAZAP2
DAZ associated protein 2
chr10_+_70883908 0.472 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
 VPS26A



vacuolar protein sorting 26 homolog A (S. pombe)



chr19_+_35168633 0.471 ENST00000505365.2
 ZNF302
zinc finger protein 302
chr8_+_74903580 0.465 ENST00000284818.2
ENST00000518893.1
 LY96

lymphocyte antigen 96

chr8_+_22436635 0.464 ENST00000452226.1
ENST00000397760.4
ENST00000339162.7
ENST00000397761.2
 PDLIM2



PDZ and LIM domain 2 (mystique)



chr2_+_223916862 0.451 ENST00000604125.1
 KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr7_+_23286182 0.449 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
 GPNMB




glycoprotein (transmembrane) nmb




chr5_-_150537279 0.448 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
 ANXA6





annexin A6





chr3_-_45883558 0.447 ENST00000445698.1
ENST00000296135.6
 LZTFL1

leucine zipper transcription factor-like 1

chr7_+_100271446 0.444 ENST00000419828.1
ENST00000427895.1
 GNB2

guanine nucleotide binding protein (G protein), beta polypeptide 2

chr4_+_78078304 0.441 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
 CCNG2


cyclin G2


chr17_-_17875688 0.438 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
 TOM1L2







target of myb1-like 2 (chicken)







chr12_+_54378923 0.437 ENST00000303460.4
 HOXC10
homeobox C10
chr10_+_51827648 0.435 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
 FAM21A


family with sequence similarity 21, member A


chr13_+_43597269 0.434 ENST00000379221.2
 DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr7_-_38948774 0.431 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
 VPS41


vacuolar protein sorting 41 homolog (S. cerevisiae)


chr12_-_49318715 0.430 ENST00000444214.2
 FKBP11
FK506 binding protein 11, 19 kDa
chr9_-_125667618 0.429 ENST00000423239.2
 RC3H2
ring finger and CCCH-type domains 2
chr13_-_50367057 0.419 ENST00000261667.3
 KPNA3
karyopherin alpha 3 (importin alpha 4)
chrX_+_10124977 0.417 ENST00000380833.4
 CLCN4
chloride channel, voltage-sensitive 4
chr9_-_21995300 0.417 ENST00000498628.2
 CDKN2A
cyclin-dependent kinase inhibitor 2A
chr1_+_42922173 0.413 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
 PPCS



phosphopantothenoylcysteine synthetase



chr10_-_93392811 0.411 ENST00000238994.5
 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr21_-_46237959 0.410 ENST00000397898.3
ENST00000411651.2
 SUMO3

small ubiquitin-like modifier 3

chr3_+_134204551 0.410 ENST00000332047.5
ENST00000354446.3
 CEP63

centrosomal protein 63kDa

chr9_-_135819987 0.406 ENST00000298552.3
ENST00000403810.1
 TSC1

tuberous sclerosis 1

chr22_-_17640110 0.405 ENST00000399852.3
ENST00000336737.4
 CECR5

cat eye syndrome chromosome region, candidate 5

chr8_+_22436248 0.404 ENST00000308354.7
 PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_-_47470591 0.404 ENST00000524487.1
 RAPSN
receptor-associated protein of the synapse
chr7_-_27183263 0.402 ENST00000222726.3
 HOXA5
homeobox A5
chr17_-_35969409 0.398 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
 SYNRG







synergin, gamma







chr22_+_35776828 0.397 ENST00000216117.8
 HMOX1
heme oxygenase (decycling) 1
chr14_-_69445793 0.396 ENST00000538545.2
ENST00000394419.4
 ACTN1

actinin, alpha 1

chrX_-_9734004 0.395 ENST00000467482.1
ENST00000380929.2
 GPR143

G protein-coupled receptor 143

chr12_+_69139886 0.384 ENST00000398004.2
 SLC35E3
solute carrier family 35, member E3
chr1_-_39325431 0.384 ENST00000373001.3
 RRAGC
Ras-related GTP binding C
chr1_-_27998689 0.382 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
 IFI6


interferon, alpha-inducible protein 6


chr4_+_76439665 0.379 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
 THAP6







THAP domain containing 6







chr12_+_12878829 0.379 ENST00000326765.6
 APOLD1
apolipoprotein L domain containing 1
chr11_-_47470703 0.376 ENST00000298854.2
 RAPSN
receptor-associated protein of the synapse
chr2_-_197036289 0.376 ENST00000263955.4
 STK17B
serine/threonine kinase 17b
chr1_-_26233423 0.376 ENST00000357865.2
 STMN1
stathmin 1
chr11_-_61560053 0.374 ENST00000537328.1
 TMEM258
transmembrane protein 258
chr15_+_75628232 0.372 ENST00000267935.8
ENST00000567195.1
 COMMD4

COMM domain containing 4

chr11_-_61560254 0.372 ENST00000543510.1
 TMEM258
transmembrane protein 258
chr11_-_85780086 0.372 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
 PICALM


phosphatidylinositol binding clathrin assembly protein


chr2_+_242254507 0.370 ENST00000391973.2
 SEPT2
septin 2
chr6_+_127587755 0.370 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146





ring finger protein 146





chr17_+_17876127 0.369 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
 LRRC48









leucine rich repeat containing 48









chr9_+_115913222 0.368 ENST00000259392.3
 SLC31A2
solute carrier family 31 (copper transporter), member 2
chr10_-_14050522 0.368 ENST00000342409.2
 FRMD4A
FERM domain containing 4A
chr12_+_51633061 0.367 ENST00000551313.1
 DAZAP2
DAZ associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.9 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.9 6.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.7 2.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.7 3.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.5 5.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.3 GO:0006089 lactate metabolic process(GO:0006089)
0.3 0.9 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.3 0.9 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.3 1.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 0.8 GO:0021570 rhombomere 4 development(GO:0021570) facial nucleus development(GO:0021754)
0.3 2.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.3 1.8 GO:0045176 apical protein localization(GO:0045176)
0.3 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.2 1.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) long-term synaptic potentiation(GO:0060291)
0.2 0.7 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 1.1 GO:2000124 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.6 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 1.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 2.1 GO:0048268 negative regulation of receptor-mediated endocytosis(GO:0048261) clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0060574 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
0.1 0.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0002887 wound healing involved in inflammatory response(GO:0002246) negative regulation of myeloid leukocyte mediated immunity(GO:0002887) heme oxidation(GO:0006788) smooth muscle hyperplasia(GO:0014806) muscle hyperplasia(GO:0014900) negative regulation of leukocyte degranulation(GO:0043301) inflammatory response to wounding(GO:0090594)
0.1 1.6 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.9 GO:0006681 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.1 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 1.9 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.5 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1 4.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 2.5 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.3 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 1.9 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.1 2.2 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 0.8 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 5.3 GO:0006914 autophagy(GO:0006914)
0.1 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.3 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1 0.6 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.3 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 3.3 GO:0051318 G1 phase(GO:0051318)
0.1 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.1 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.1 1.5 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 0.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.8 GO:0007032 endosome organization(GO:0007032)
0.1 0.3 GO:0051297 microtubule organizing center organization(GO:0031023) centrosome organization(GO:0051297)
0.0 0.7 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.8 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 3.0 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.2 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 3.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.3 GO:0045008 depyrimidination(GO:0045008)
0.0 0.1 GO:0010950 positive regulation of endopeptidase activity(GO:0010950)
0.0 0.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 4.4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281)
0.0 0.3 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 1.3 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.0 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 1.0 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 1.7 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242) negative regulation of vasodilation(GO:0045908) regulation of mucus secretion(GO:0070255) negative regulation of mucus secretion(GO:0070256)
0.0 0.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.1 GO:0046604 regulation of mitotic centrosome separation(GO:0046602) positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.5 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 1.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.5 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.6 GO:0070542 response to fatty acid(GO:0070542)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.8 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0048193 Golgi vesicle transport(GO:0048193)
0.0 0.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.0 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.5 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.0 0.2 GO:0042976 activation of Janus kinase activity(GO:0042976) activation of JAK2 kinase activity(GO:0042977)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:1901998 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0051100 negative regulation of binding(GO:0051100)
0.0 0.0 GO:0071344 diphosphate metabolic process(GO:0071344)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:0051789 obsolete response to protein(GO:0051789)
0.0 0.0 GO:0014831 intestine smooth muscle contraction(GO:0014827) gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0046831 regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0002381 somatic recombination of immunoglobulin genes involved in immune response(GO:0002204) somatic diversification of immunoglobulins involved in immune response(GO:0002208) immunoglobulin production involved in immunoglobulin mediated immune response(GO:0002381) isotype switching(GO:0045190)
0.0 0.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.9 GO:0015698 inorganic anion transport(GO:0015698)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.6 1.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.5 1.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.4 8.2 GO:0005771 multivesicular body(GO:0005771)
0.4 5.3 GO:0071203 WASH complex(GO:0071203)
0.3 1.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 2.1 GO:0000145 exocyst(GO:0000145)
0.2 0.6 GO:0030904 retromer complex(GO:0030904)
0.2 0.7 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.2 0.7 GO:0070695 FHF complex(GO:0070695)
0.2 1.7 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.1 2.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 1.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.5 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 2.0 GO:0046930 pore complex(GO:0046930)
0.1 1.3 GO:0031143 pseudopodium(GO:0031143)
0.1 1.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 7.4 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 2.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0005859 muscle myosin complex(GO:0005859)
0.0 1.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.5 GO:0000922 spindle pole(GO:0000922)
0.0 1.1 GO:0016020 membrane(GO:0016020)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0009986 cell surface(GO:0009986)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.8 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 2.9 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.1 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.9 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937) histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0000776 kinetochore(GO:0000776)
0.0 2.3 GO:0005911 cell-cell junction(GO:0005911)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.7 5.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 2.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.4 2.2 GO:0051434 BH3 domain binding(GO:0051434)
0.4 1.9 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.3 3.4 GO:0031419 cobalamin binding(GO:0031419)
0.3 0.9 GO:0043199 sulfate binding(GO:0043199)
0.3 0.9 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.3 4.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 1.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2 2.1 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 0.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.2 GO:0004630 phospholipase D activity(GO:0004630)
0.2 1.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.2 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 3.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.1 1.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.4 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 3.0 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.6 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 0.4 GO:0035240 dopamine binding(GO:0035240)
0.1 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.7 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.1 3.5 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.1 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403) polynucleotide phosphatase activity(GO:0098518)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.6 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0050816 beta-2 adrenergic receptor binding(GO:0031698) phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.3 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.6 GO:0019829 cation-transporting ATPase activity(GO:0019829)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.2 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.5 GO:0051287 NAD binding(GO:0051287)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0008493 tetracycline transporter activity(GO:0008493)
0.0 1.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 2.3 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 1.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.1 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0015295 solute:proton symporter activity(GO:0015295)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.9 ST_GAQ_PATHWAY G alpha q Pathway
0.0 0.6 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway