Motif ID: TGIF1
Z-value: 1.949
Transcription factors associated with TGIF1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| TGIF1 | ENSG00000177426.16 | TGIF1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 12.1 | GO:2000124 | cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
| 1.1 | 9.8 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 1.1 | 4.3 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.5 | 3.1 | GO:0060263 | regulation of respiratory burst(GO:0060263) |
| 0.5 | 1.9 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.5 | 1.8 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.4 | 1.3 | GO:0097709 | connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709) |
| 0.4 | 3.5 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.4 | 1.2 | GO:0031394 | regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
| 0.4 | 3.1 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.4 | 1.2 | GO:0046931 | pore complex assembly(GO:0046931) |
| 0.4 | 1.1 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.3 | 2.0 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.3 | 1.4 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
| 0.3 | 0.8 | GO:0071280 | epithelial fluid transport(GO:0042045) cellular response to copper ion(GO:0071280) |
| 0.3 | 0.8 | GO:0006740 | NADPH regeneration(GO:0006740) |
| 0.3 | 2.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 1.5 | GO:0043316 | natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320) |
| 0.2 | 4.3 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.2 | 0.8 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.2 | 0.6 | GO:0060831 | smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831) |
| 0.2 | 0.6 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
| 0.2 | 2.9 | GO:0050812 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812) |
| 0.2 | 1.1 | GO:0030007 | cellular potassium ion homeostasis(GO:0030007) negative regulation of cell volume(GO:0045794) |
| 0.1 | 0.9 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.1 | 0.5 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.1 | 0.5 | GO:0042262 | DNA protection(GO:0042262) |
| 0.1 | 0.4 | GO:0033025 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 0.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.1 | 0.8 | GO:0060414 | aorta development(GO:0035904) aorta morphogenesis(GO:0035909) aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.1 | 0.3 | GO:0050758 | thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.1 | 0.2 | GO:0001845 | phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382) |
| 0.1 | 0.4 | GO:0009296 | obsolete flagellum assembly(GO:0009296) |
| 0.1 | 1.3 | GO:0032456 | endocytic recycling(GO:0032456) |
| 0.1 | 0.3 | GO:0006668 | sphinganine-1-phosphate metabolic process(GO:0006668) |
| 0.1 | 0.5 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.1 | 0.2 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
| 0.1 | 0.9 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.1 | 0.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 0.2 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.1 | 0.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 2.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.7 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
| 0.1 | 0.1 | GO:0060398 | regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 0.1 | 0.3 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 0.1 | 0.4 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 1.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.1 | 1.2 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.1 | 1.6 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.1 | 0.2 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.1 | 0.7 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.0 | 1.1 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
| 0.0 | 0.3 | GO:0019372 | lipoxygenase pathway(GO:0019372) |
| 0.0 | 0.9 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.2 | GO:0045349 | interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.0 | 0.3 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.0 | 0.4 | GO:0098927 | early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927) |
| 0.0 | 0.2 | GO:0042637 | catagen(GO:0042637) |
| 0.0 | 0.2 | GO:0008228 | opsonization(GO:0008228) |
| 0.0 | 0.4 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 2.1 | GO:0032387 | negative regulation of intracellular transport(GO:0032387) |
| 0.0 | 0.3 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.9 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.8 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.0 | 1.0 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.9 | GO:0045103 | intermediate filament-based process(GO:0045103) |
| 0.0 | 0.6 | GO:0001662 | behavioral fear response(GO:0001662) |
| 0.0 | 0.3 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.4 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.6 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.0 | 0.3 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.0 | 0.1 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
| 0.0 | 1.1 | GO:0050931 | melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931) |
| 0.0 | 1.3 | GO:0051101 | regulation of DNA binding(GO:0051101) |
| 0.0 | 3.7 | GO:0065004 | protein-DNA complex assembly(GO:0065004) |
| 0.0 | 0.1 | GO:0007100 | mitotic centrosome separation(GO:0007100) |
| 0.0 | 0.1 | GO:0045908 | negative regulation of vasodilation(GO:0045908) |
| 0.0 | 0.2 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) |
| 0.0 | 0.2 | GO:0071354 | cellular response to interleukin-6(GO:0071354) |
| 0.0 | 0.2 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.7 | GO:0044349 | nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) |
| 0.0 | 0.1 | GO:0034287 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
| 0.0 | 1.8 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.0 | GO:2000831 | corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846) |
| 0.0 | 0.1 | GO:1903960 | negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192) |
| 0.0 | 0.3 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.6 | GO:0055007 | cardiac muscle cell differentiation(GO:0055007) |
| 0.0 | 0.2 | GO:0043306 | regulation of mast cell activation involved in immune response(GO:0033006) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) regulation of mast cell degranulation(GO:0043304) positive regulation of mast cell degranulation(GO:0043306) |
| 0.0 | 0.4 | GO:0000303 | response to superoxide(GO:0000303) |
| 0.0 | 0.1 | GO:0044254 | angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268) |
| 0.0 | 0.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.3 | GO:0008634 | obsolete negative regulation of survival gene product expression(GO:0008634) |
| 0.0 | 0.4 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
| 0.0 | 0.4 | GO:0002504 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.0 | 0.1 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.0 | 0.4 | GO:0007389 | pattern specification process(GO:0007389) |
| 0.0 | 1.2 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.3 | GO:0030968 | endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620) |
| 0.0 | 0.5 | GO:0021549 | cerebellum development(GO:0021549) |
| 0.0 | 0.2 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.3 | GO:0006360 | transcription from RNA polymerase I promoter(GO:0006360) |
| 0.0 | 1.0 | GO:0006892 | post-Golgi vesicle-mediated transport(GO:0006892) |
| 0.0 | 1.4 | GO:0006839 | mitochondrial transport(GO:0006839) |
| 0.0 | 0.3 | GO:0016079 | synaptic vesicle exocytosis(GO:0016079) |
| 0.0 | 0.6 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.1 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 2.0 | GO:0006813 | potassium ion transport(GO:0006813) |
| 0.0 | 0.4 | GO:0051693 | actin filament capping(GO:0051693) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.4 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.3 | 0.8 | GO:0033655 | host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.3 | 1.0 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.3 | 0.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.2 | 0.9 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.2 | 2.0 | GO:0001950 | obsolete plasma membrane enriched fraction(GO:0001950) |
| 0.2 | 2.5 | GO:0001527 | microfibril(GO:0001527) |
| 0.1 | 3.1 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.1 | 1.4 | GO:0031094 | platelet dense tubular network(GO:0031094) |
| 0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 1.1 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 0.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.4 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.1 | 0.3 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 0.2 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.0 | 3.0 | GO:0008287 | protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293) |
| 0.0 | 0.2 | GO:0001740 | Barr body(GO:0001740) |
| 0.0 | 0.2 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.5 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 2.5 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.0 | 0.7 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.1 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.8 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
| 0.0 | 9.8 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 1.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 1.3 | GO:0030175 | filopodium(GO:0030175) |
| 0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 1.7 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 0.2 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.0 | 0.1 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 0.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.2 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.7 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.5 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.2 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.0 | 0.4 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.9 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 0.1 | GO:0098984 | asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.5 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 1.1 | 4.3 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.9 | 12.1 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.6 | 2.9 | GO:0004741 | magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.3 | 1.4 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
| 0.3 | 3.7 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
| 0.3 | 0.8 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 0.3 | 1.1 | GO:0016635 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.3 | 0.8 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.2 | 0.7 | GO:0019797 | procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544) |
| 0.2 | 2.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 7.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.2 | 1.3 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.2 | 1.5 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.2 | 0.8 | GO:0050833 | pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833) |
| 0.2 | 0.5 | GO:0030611 | arsenate reductase activity(GO:0030611) |
| 0.2 | 1.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.2 | 1.1 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.2 | 0.8 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 1.1 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.1 | 0.5 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 1.2 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.5 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 0.5 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 0.5 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 1.6 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 0.3 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 0.4 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 3.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 0.5 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.1 | 0.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 2.1 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 2.1 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.3 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 2.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.3 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 0.1 | 0.4 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.1 | 0.3 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542) |
| 0.1 | 1.8 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 4.3 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.1 | 0.4 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
| 0.1 | 0.9 | GO:0001619 | obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619) |
| 0.1 | 1.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 1.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.1 | 0.3 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 0.1 | 1.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 6.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.2 | GO:0005543 | phospholipid binding(GO:0005543) |
| 0.1 | 1.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.2 | GO:0033265 | choline binding(GO:0033265) |
| 0.0 | 0.2 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.0 | 1.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.3 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.2 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.0 | 1.9 | GO:1990782 | receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782) |
| 0.0 | 1.2 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 0.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 1.1 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.0 | 0.2 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.0 | 0.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.0 | 0.8 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.4 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 0.3 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.0 | 0.1 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.6 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 1.0 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.2 | GO:0051635 | obsolete bacterial cell surface binding(GO:0051635) |
| 0.0 | 1.3 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 0.1 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.0 | 0.1 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.0 | 0.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 0.1 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.0 | 0.1 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.3 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.1 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 0.0 | 0.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.2 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.6 | GO:0050136 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.2 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.6 | GO:0019208 | phosphatase regulator activity(GO:0019208) |
| 0.0 | 0.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.0 | 0.3 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.2 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.3 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.1 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 4.7 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 2.6 | ST_FAS_SIGNALING_PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.9 | ST_T_CELL_SIGNAL_TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 0.4 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.9 | SIG_CHEMOTAXIS | Genes related to chemotaxis |
