Motif ID: TWIST1_SNAI1

Z-value: 2.020

Transcription factors associated with TWIST1_SNAI1:

Gene SymbolEntrez IDGene Name
SNAI1 ENSG00000124216.3 SNAI1
TWIST1 ENSG00000122691.8 TWIST1






Network of associatons between targets according to the STRING database.



First level regulatory network of TWIST1_SNAI1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_111314230 4.282 ENST00000317012.4
ZBED2
zinc finger, BED-type containing 2
chr1_+_35247859 4.074 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr18_+_29077990 3.669 ENST00000261590.8
DSG2
desmoglein 2
chr19_+_35609380 3.172 ENST00000604621.1
FXYD3
FXYD domain containing ion transport regulator 3
chr17_-_39677971 2.948 ENST00000393976.2
KRT15
keratin 15
chrX_+_105969893 2.939 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr12_+_52626898 2.425 ENST00000331817.5
KRT7
keratin 7
chr2_+_47596287 2.405 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr19_-_51456198 2.256 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr19_+_38755042 2.126 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr11_+_66824276 2.059 ENST00000308831.2
RHOD
ras homolog family member D
chr6_+_7541808 1.948 ENST00000379802.3
DSP
desmoplakin
chr6_+_7541845 1.944 ENST00000418664.2
DSP
desmoplakin
chr4_+_89299885 1.887 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chr16_+_68679193 1.812 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr8_-_81083890 1.713 ENST00000518937.1
TPD52
tumor protein D52
chr21_-_43187231 1.664 ENST00000332512.3
ENST00000352483.2
RIPK4

receptor-interacting serine-threonine kinase 4

chr19_+_38755203 1.637 ENST00000587090.1
ENST00000454580.3
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr4_-_10023095 1.597 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_-_10419871 1.545 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_160990886 1.522 ENST00000537746.1
F11R
F11 receptor
chr1_-_95007193 1.511 ENST00000370207.4
ENST00000334047.7
F3

coagulation factor III (thromboplastin, tissue factor)

chr15_+_101420028 1.507 ENST00000557963.1
ENST00000346623.6
ALDH1A3

aldehyde dehydrogenase 1 family, member A3

chr17_+_52978156 1.503 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chr4_+_4387983 1.493 ENST00000397958.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr1_-_209979375 1.478 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr12_+_53342625 1.459 ENST00000388837.2
ENST00000550600.1
ENST00000388835.3
KRT18


keratin 18


chr12_+_6309517 1.444 ENST00000382519.4
ENST00000009180.4
CD9

CD9 molecule

chr16_+_68678739 1.442 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr15_+_41136586 1.424 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_+_68678892 1.405 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr16_-_4987065 1.404 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr17_-_39553844 1.390 ENST00000251645.2
KRT31
keratin 31
chr17_-_39780819 1.362 ENST00000311208.8
KRT17
keratin 17
chr19_+_35606692 1.320 ENST00000406242.3
ENST00000454903.2
FXYD3

FXYD domain containing ion transport regulator 3

chr8_+_12809093 1.273 ENST00000528753.2
KIAA1456
KIAA1456
chr11_+_66824346 1.253 ENST00000532559.1
RHOD
ras homolog family member D
chr11_-_119993979 1.234 ENST00000524816.3
ENST00000525327.1
TRIM29

tripartite motif containing 29

chr11_-_88070920 1.191 ENST00000524463.1
ENST00000227266.5
CTSC

cathepsin C

chr1_-_93426998 1.170 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr14_-_67878917 1.146 ENST00000216446.4
PLEK2
pleckstrin 2
chr18_+_47088401 1.145 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr17_+_52978107 1.138 ENST00000445275.2
TOM1L1
target of myb1 (chicken)-like 1
chr22_+_31489344 1.117 ENST00000404574.1
SMTN
smoothelin
chr2_+_102615416 1.095 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr17_+_39411636 1.061 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr1_+_156030937 0.997 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr1_-_201368707 0.994 ENST00000391967.2
LAD1
ladinin 1
chr16_+_68771128 0.989 ENST00000261769.5
ENST00000422392.2
CDH1

cadherin 1, type 1, E-cadherin (epithelial)

chr17_+_73717407 0.976 ENST00000579662.1
ITGB4
integrin, beta 4
chr20_+_48807351 0.945 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr9_-_112083229 0.940 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr8_-_81083731 0.928 ENST00000379096.5
TPD52
tumor protein D52
chr19_-_42806723 0.923 ENST00000262890.3
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr8_-_80993010 0.899 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52




tumor protein D52




chr7_+_76054224 0.888 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr4_+_89299994 0.873 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_+_1981890 0.869 ENST00000378567.3
ENST00000468310.1
PRKCZ

protein kinase C, zeta

chr3_-_197282821 0.865 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1





3-hydroxybutyrate dehydrogenase, type 1





chr1_-_201368653 0.830 ENST00000367313.3
LAD1
ladinin 1
chr18_-_74844713 0.829 ENST00000397860.3
MBP
myelin basic protein
chr3_+_50654550 0.827 ENST00000430409.1
ENST00000357955.2
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chr1_+_60280458 0.825 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr2_+_64681103 0.801 ENST00000464281.1
LGALSL
lectin, galactoside-binding-like
chr14_-_61747949 0.787 ENST00000355702.2
TMEM30B
transmembrane protein 30B
chr19_-_10697895 0.785 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2




adaptor-related protein complex 1, mu 2 subunit




chr2_+_64681219 0.784 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr12_-_48298785 0.739 ENST00000550325.1
ENST00000546653.1
ENST00000549336.1
ENST00000535672.1
ENST00000229022.3
ENST00000548664.1
VDR





vitamin D (1,25- dihydroxyvitamin D3) receptor





chr10_+_75910960 0.738 ENST00000539909.1
ENST00000286621.2
ADK

adenosine kinase

chr19_-_45908292 0.737 ENST00000360957.5
ENST00000592134.1
PPP1R13L

protein phosphatase 1, regulatory subunit 13 like

chr19_+_751122 0.727 ENST00000215582.6
MISP
mitotic spindle positioning
chr8_-_145028013 0.725 ENST00000354958.2
PLEC
plectin
chr12_+_6309963 0.719 ENST00000382515.2
CD9
CD9 molecule
chr17_+_73750699 0.716 ENST00000584939.1
ITGB4
integrin, beta 4
chr7_+_73242490 0.713 ENST00000431918.1
CLDN4
claudin 4
chr7_+_55086794 0.698 ENST00000275493.2
ENST00000442591.1
EGFR

epidermal growth factor receptor

chr14_-_23652849 0.697 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8



solute carrier family 7 (amino acid transporter light chain, L system), member 8



chr11_+_118958689 0.678 ENST00000535253.1
ENST00000392841.1
HMBS

hydroxymethylbilane synthase

chr4_-_40631859 0.676 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr20_-_60942361 0.672 ENST00000252999.3
LAMA5
laminin, alpha 5
chr19_-_42806842 0.669 ENST00000596265.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr17_+_73521763 0.667 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr7_+_73242069 0.659 ENST00000435050.1
CLDN4
claudin 4
chr4_-_84255935 0.651 ENST00000513463.1
HPSE
heparanase
chr2_+_17721920 0.648 ENST00000295156.4
VSNL1
visinin-like 1
chr1_-_113498616 0.625 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1


solute carrier family 16 (monocarboxylate transporter), member 1


chr19_+_18794470 0.623 ENST00000321949.8
ENST00000338797.6
CRTC1

CREB regulated transcription coactivator 1

chr1_+_44399466 0.617 ENST00000498139.2
ENST00000491846.1
ARTN

artemin

chr5_+_150400124 0.616 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3


glutathione peroxidase 3 (plasma)


chr2_+_234621551 0.614 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_-_3773747 0.613 ENST00000428079.1
ENST00000378230.3
ENST00000378223.3
CEP104


centrosomal protein 104kDa


chr3_-_48481434 0.611 ENST00000395694.2
ENST00000447018.1
ENST00000442740.1
CCDC51


coiled-coil domain containing 51


chr12_-_27167233 0.609 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3






transmembrane 7 superfamily member 3






chr3_-_48481518 0.578 ENST00000412398.2
ENST00000395696.1
CCDC51

coiled-coil domain containing 51

chr14_-_24036943 0.569 ENST00000556843.1
ENST00000397120.3
ENST00000557189.1
AP1G2


adaptor-related protein complex 1, gamma 2 subunit


chr8_-_110656995 0.568 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr1_-_184943610 0.559 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr14_-_51411194 0.555 ENST00000544180.2
PYGL
phosphorylase, glycogen, liver
chr1_+_19923454 0.551 ENST00000322753.6
ENST00000602662.1
ENST00000602293.1
MINOS1
MINOS1-NBL1

mitochondrial inner membrane organizing system 1
MINOS1-NBL1 readthrough

chr17_-_39684550 0.548 ENST00000455635.1
ENST00000361566.3
KRT19

keratin 19

chr1_+_233749739 0.548 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr11_-_65667997 0.542 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr4_-_57522598 0.539 ENST00000553379.2
HOPX
HOP homeobox
chr4_-_57522673 0.530 ENST00000381255.3
ENST00000317745.7
ENST00000555760.2
ENST00000556614.2
HOPX



HOP homeobox



chr4_-_36246060 0.530 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_-_53074182 0.528 ENST00000252244.3
KRT1
keratin 1
chr16_+_67233412 0.525 ENST00000477898.1
ELMO3
engulfment and cell motility 3
chr11_+_394196 0.514 ENST00000331563.2
ENST00000531857.1
PKP3

plakophilin 3

chr19_-_42806919 0.511 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3


platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)


chr12_+_57984965 0.506 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr12_+_125549973 0.501 ENST00000536752.1
ENST00000261686.6
AACS

acetoacetyl-CoA synthetase

chr8_+_12808834 0.501 ENST00000400069.3
KIAA1456
KIAA1456
chr1_+_32042131 0.499 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr6_-_30043539 0.499 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr16_+_23847339 0.494 ENST00000303531.7
PRKCB
protein kinase C, beta
chr12_+_125549925 0.490 ENST00000316519.6
AACS
acetoacetyl-CoA synthetase
chr19_+_45281118 0.488 ENST00000270279.3
ENST00000341505.4
CBLC

Cbl proto-oncogene C, E3 ubiquitin protein ligase

chr18_-_12884259 0.488 ENST00000353319.4
ENST00000327283.3
PTPN2

protein tyrosine phosphatase, non-receptor type 2

chrX_+_115567767 0.471 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr8_+_32405728 0.469 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr1_+_109792641 0.469 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr17_-_27503770 0.468 ENST00000533112.1
MYO18A
myosin XVIIIA
chr14_+_75746781 0.465 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_111718036 0.458 ENST00000455401.2
TAGLN3
transgelin 3
chr11_-_65667884 0.455 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr13_+_76123883 0.454 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr11_-_118972575 0.449 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr4_-_57522470 0.448 ENST00000503639.3
HOPX
HOP homeobox
chr20_-_16554078 0.441 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
KIF16B



kinesin family member 16B



chr19_+_35739280 0.441 ENST00000602122.1
LSR
lipolysis stimulated lipoprotein receptor
chr3_+_111717600 0.440 ENST00000273368.4
TAGLN3
transgelin 3
chr8_+_32405785 0.434 ENST00000287842.3
NRG1
neuregulin 1
chr8_-_145018905 0.434 ENST00000398774.2
PLEC
plectin
chr20_-_10654639 0.432 ENST00000254958.5
JAG1
jagged 1
chr7_+_16793160 0.432 ENST00000262067.4
TSPAN13
tetraspanin 13
chr12_-_51785182 0.431 ENST00000356317.3
ENST00000603188.1
ENST00000604847.1
ENST00000604506.1
GALNT6



UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)



chr7_+_55086703 0.427 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR



epidermal growth factor receptor



chr19_+_33865218 0.426 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr11_+_64948665 0.408 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr10_-_118764862 0.399 ENST00000260777.10
KIAA1598
KIAA1598
chr19_-_19739007 0.391 ENST00000586703.1
ENST00000591042.1
ENST00000407877.3
LPAR2


lysophosphatidic acid receptor 2


chr5_+_167718604 0.390 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr13_-_52027134 0.381 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr17_-_79869228 0.381 ENST00000570388.1
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr17_-_27507395 0.378 ENST00000354329.4
ENST00000527372.1
MYO18A

myosin XVIIIA

chrX_+_16804544 0.374 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr15_+_67547163 0.371 ENST00000335894.4
IQCH
IQ motif containing H
chr1_+_24882560 0.369 ENST00000374392.2
NCMAP
noncompact myelin associated protein
chr1_+_155051305 0.368 ENST00000368408.3
EFNA3
ephrin-A3
chr17_-_79166176 0.368 ENST00000571292.1
AZI1
5-azacytidine induced 1
chr3_+_167453493 0.365 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr2_-_10588630 0.357 ENST00000234111.4
ODC1
ornithine decarboxylase 1
chr8_-_99306611 0.355 ENST00000341166.3
NIPAL2
NIPA-like domain containing 2
chr10_-_35104185 0.354 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3










par-3 family cell polarity regulator










chr1_-_150669604 0.354 ENST00000427665.1
ENST00000540514.1
GOLPH3L

golgi phosphoprotein 3-like

chr5_+_95998746 0.351 ENST00000508608.1
CAST
calpastatin
chr2_-_209118974 0.348 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1


isocitrate dehydrogenase 1 (NADP+), soluble


chr17_-_79869077 0.348 ENST00000570391.1
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr1_-_111746966 0.339 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr17_+_4843679 0.339 ENST00000576229.1
RNF167
ring finger protein 167
chr16_-_84538218 0.336 ENST00000562447.1
ENST00000565765.1
ENST00000535580.1
ENST00000343629.6
TLDC1



TBC/LysM-associated domain containing 1



chr6_-_41040195 0.335 ENST00000463088.1
ENST00000469104.1
ENST00000486443.1
OARD1


O-acyl-ADP-ribose deacylase 1


chr6_-_41040268 0.334 ENST00000373154.2
ENST00000244558.9
ENST00000464633.1
ENST00000424266.2
ENST00000479950.1
ENST00000482515.1
OARD1





O-acyl-ADP-ribose deacylase 1





chr3_-_167452262 0.334 ENST00000487947.2
PDCD10
programmed cell death 10
chr12_-_33049690 0.333 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chr8_+_56014949 0.332 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr17_+_76164639 0.330 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2




synaptogyrin 2




chr1_-_156675368 0.330 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr6_+_149068464 0.324 ENST00000367463.4
UST
uronyl-2-sulfotransferase
chr1_-_153433120 0.324 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr6_-_41039567 0.323 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr10_+_124134201 0.322 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1



pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1



chrX_+_70443050 0.319 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr19_+_39989535 0.319 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr7_+_98972345 0.315 ENST00000418347.2
ENST00000429246.1
ENST00000417330.1
ENST00000431816.1
ENST00000427217.1
ENST00000458033.1
ENST00000451682.1
ARPC1B






actin related protein 2/3 complex, subunit 1B, 41kDa






chr15_+_31658349 0.311 ENST00000558844.1
KLF13
Kruppel-like factor 13
chr5_+_44809027 0.311 ENST00000507110.1
MRPS30
mitochondrial ribosomal protein S30
chr19_+_10216899 0.311 ENST00000253107.7
ENST00000556468.1
ENST00000393793.1
ENST00000428358.1
ENST00000393796.4
PPAN


PPAN-P2RY11

peter pan homolog (Drosophila)


PPAN-P2RY11 readthrough

chr15_-_71055878 0.311 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_-_100881466 0.310 ENST00000341469.2
ENST00000342043.3
ENST00000375098.3
TRIM14


tripartite motif containing 14


chr15_-_48937884 0.303 ENST00000560355.1
FBN1
fibrillin 1
chr19_-_18391708 0.301 ENST00000600972.1
JUND
jun D proto-oncogene
chr14_-_55369525 0.300 ENST00000543643.2
ENST00000536224.2
ENST00000395514.1
ENST00000491895.2
GCH1



GTP cyclohydrolase 1



chr1_+_100315613 0.298 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr22_-_50964849 0.294 ENST00000543927.1
ENST00000423348.1
SCO2

SCO2 cytochrome c oxidase assembly protein

chr2_-_25896380 0.293 ENST00000545439.1
ENST00000407186.1
ENST00000406818.3
ENST00000404103.3
ENST00000407661.3
ENST00000407038.3
ENST00000405222.1
ENST00000288642.8
DTNB







dystrobrevin, beta







chr22_+_30792846 0.292 ENST00000312932.9
ENST00000428195.1
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr6_+_33172407 0.291 ENST00000374662.3
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr7_-_75677251 0.289 ENST00000431581.1
ENST00000359697.3
ENST00000451157.1
ENST00000340062.5
ENST00000360591.3
ENST00000248600.1
STYXL1





serine/threonine/tyrosine interacting-like 1





chr17_+_4843654 0.288 ENST00000575111.1
RNF167
ring finger protein 167
chr17_+_7284365 0.287 ENST00000311668.2
TNK1
tyrosine kinase, non-receptor, 1
chr19_-_2042065 0.284 ENST00000591588.1
ENST00000591142.1
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr1_+_220701740 0.283 ENST00000366917.4
MARK1
MAP/microtubule affinity-regulating kinase 1
chr2_+_74056066 0.283 ENST00000339566.3
ENST00000409707.1
ENST00000452725.1
ENST00000432295.2
ENST00000424659.1
ENST00000394073.1
STAMBP





STAM binding protein





chr7_+_130020180 0.280 ENST00000481342.1
ENST00000011292.3
ENST00000604896.1
CPA1


carboxypeptidase A1 (pancreatic)


chr13_+_28194873 0.278 ENST00000302979.3
POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr11_+_59522532 0.276 ENST00000337979.4
ENST00000535361.1
STX3

syntaxin 3

chr11_+_13299186 0.276 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL












aryl hydrocarbon receptor nuclear translocator-like












chr2_+_74056147 0.273 ENST00000394070.2
ENST00000536064.1
STAMBP

STAM binding protein

chrX_+_114795489 0.273 ENST00000355899.3
ENST00000537301.1
ENST00000289290.3
PLS3


plastin 3



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.5 1.5 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.5 1.9 GO:0030913 paranodal junction assembly(GO:0030913)
0.4 1.5 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.4 1.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.4 1.5 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.4 1.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 0.8 GO:0032025 response to cobalt ion(GO:0032025)
0.3 1.0 GO:0001807 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807)
0.2 1.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.7 GO:0009202 purine deoxyribonucleotide biosynthetic process(GO:0009153) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.2 1.5 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 1.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 0.6 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 0.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 1.0 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 0.6 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.7 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 0.9 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.2 0.9 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 2.4 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.2 0.5 GO:0060896 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.1 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.4 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 0.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.6 GO:0006789 bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.1 0.6 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.1 4.1 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.6 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.4 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.4 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 2.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 2.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.2 GO:0031077 post-embryonic camera-type eye development(GO:0031077) Spemann organizer formation(GO:0060061)
0.1 0.2 GO:0019056 modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.8 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.1 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.7 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.4 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.1 1.3 GO:0031424 keratinization(GO:0031424)
0.1 0.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.3 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 1.5 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.2 GO:0002575 basophil chemotaxis(GO:0002575)
0.1 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0060023 soft palate development(GO:0060023)
0.1 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 4.2 GO:0006821 chloride transport(GO:0006821)
0.1 0.6 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0010820 T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406)
0.1 7.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.0 1.4 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 3.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 4.3 GO:0001890 placenta development(GO:0001890)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:1902803 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 6.4 GO:0008544 epidermis development(GO:0008544)
0.0 0.2 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 1.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.2 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.2 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) lung-associated mesenchyme development(GO:0060484)
0.0 4.6 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:1904742 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970) positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:1903961 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.0 GO:0072074 kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075)
0.0 0.2 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.0 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.4 GO:0098602 single organism cell adhesion(GO:0098602)
0.0 0.1 GO:0018352 glutamate decarboxylation to succinate(GO:0006540) protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.0 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.1 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 1.4 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.4 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.8 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.3 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.3 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 2.9 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.0 0.0 GO:0060969 regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0048645 organ formation(GO:0048645)
0.0 0.1 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 3.1 GO:0006417 regulation of translation(GO:0006417)
0.0 0.2 GO:0007128 meiotic prophase I(GO:0007128) male meiosis I(GO:0007141)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0034243 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0042749 circadian sleep/wake cycle process(GO:0022410) regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802)
0.0 2.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.6 GO:0061025 membrane fusion(GO:0061025)
0.0 0.0 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 GO:0005916 fascia adherens(GO:0005916)
0.3 4.3 GO:0005922 connexon complex(GO:0005922)
0.3 6.1 GO:0030057 desmosome(GO:0030057)
0.2 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.9 GO:0070695 FHF complex(GO:0070695)
0.2 0.8 GO:0033269 internode region of axon(GO:0033269)
0.2 0.8 GO:0016342 catenin complex(GO:0016342)
0.2 1.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 0.9 GO:0002080 acrosomal membrane(GO:0002080)
0.2 0.7 GO:0043259 laminin-10 complex(GO:0043259)
0.1 5.7 GO:0045095 keratin filament(GO:0045095)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 4.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 5.7 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.8 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 3.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.3 GO:0005624 obsolete membrane fraction(GO:0005624)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0019815 immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815)
0.0 0.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.4 1.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 4.3 GO:0005243 gap junction channel activity(GO:0005243)
0.3 0.9 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 1.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.2 0.6 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 1.0 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 1.6 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.2 0.7 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.2 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 0.5 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.9 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.6 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1 4.5 GO:0051117 ATPase binding(GO:0051117)
0.1 1.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.7 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 1.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 1.0 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.1 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.1 8.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 1.5 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.2 GO:0015217 purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.1 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 3.1 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.7 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) metallochaperone activity(GO:0016530) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 2.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 1.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 1.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 1.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.