Motif ID: TWIST1_SNAI1
Z-value: 2.020
Transcription factors associated with TWIST1_SNAI1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
SNAI1 | ENSG00000124216.3 | SNAI1 |
TWIST1 | ENSG00000122691.8 | TWIST1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.6 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
0.5 | 1.5 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
0.5 | 1.9 | GO:0030913 | paranodal junction assembly(GO:0030913) |
0.4 | 1.5 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.4 | 1.1 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
0.4 | 1.5 | GO:0002072 | optic cup morphogenesis involved in camera-type eye development(GO:0002072) |
0.4 | 1.1 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
0.3 | 0.8 | GO:0032025 | response to cobalt ion(GO:0032025) |
0.3 | 1.0 | GO:0001807 | type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) |
0.2 | 1.0 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.2 | 0.7 | GO:0009202 | purine deoxyribonucleotide biosynthetic process(GO:0009153) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) |
0.2 | 1.5 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
0.2 | 1.5 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
0.2 | 0.6 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
0.2 | 0.6 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
0.2 | 1.0 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
0.2 | 0.6 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.2 | 0.7 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
0.2 | 0.9 | GO:0070561 | vitamin D receptor signaling pathway(GO:0070561) |
0.2 | 0.9 | GO:0046952 | ketone body catabolic process(GO:0046952) |
0.2 | 0.5 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
0.2 | 2.4 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
0.2 | 0.5 | GO:0060896 | neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897) |
0.1 | 0.9 | GO:0060612 | adipose tissue development(GO:0060612) |
0.1 | 0.4 | GO:0035330 | regulation of hippo signaling(GO:0035330) |
0.1 | 0.5 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.1 | 0.6 | GO:0006789 | bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980) |
0.1 | 0.6 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
0.1 | 0.3 | GO:0006740 | NADPH regeneration(GO:0006740) |
0.1 | 4.1 | GO:0018149 | peptide cross-linking(GO:0018149) |
0.1 | 1.6 | GO:0046415 | urate metabolic process(GO:0046415) |
0.1 | 0.4 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
0.1 | 0.4 | GO:0008356 | asymmetric cell division(GO:0008356) |
0.1 | 0.3 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.1 | 0.3 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
0.1 | 2.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
0.1 | 0.5 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.1 | 2.2 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
0.1 | 0.5 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.1 | 1.0 | GO:0043497 | regulation of protein heterodimerization activity(GO:0043497) |
0.1 | 0.2 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
0.1 | 0.2 | GO:0031077 | post-embryonic camera-type eye development(GO:0031077) Spemann organizer formation(GO:0060061) |
0.1 | 0.2 | GO:0019056 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
0.1 | 0.2 | GO:0060535 | trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) |
0.1 | 0.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.1 | 0.2 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.1 | 0.8 | GO:0098927 | early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927) |
0.1 | 0.1 | GO:0060272 | embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498) |
0.1 | 0.2 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.1 | 0.7 | GO:0031268 | pseudopodium organization(GO:0031268) |
0.1 | 0.4 | GO:0032527 | retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527) |
0.1 | 1.3 | GO:0031424 | keratinization(GO:0031424) |
0.1 | 0.4 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
0.1 | 0.3 | GO:0006927 | obsolete transformed cell apoptotic process(GO:0006927) |
0.1 | 0.3 | GO:0060017 | parathyroid gland development(GO:0060017) |
0.1 | 1.5 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.1 | 0.2 | GO:0002575 | basophil chemotaxis(GO:0002575) |
0.1 | 0.1 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.1 | 0.2 | GO:0040016 | embryonic cleavage(GO:0040016) |
0.1 | 0.3 | GO:0010447 | response to acidic pH(GO:0010447) |
0.1 | 0.2 | GO:0060023 | soft palate development(GO:0060023) |
0.1 | 1.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.1 | 0.4 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
0.1 | 0.5 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
0.1 | 4.2 | GO:0006821 | chloride transport(GO:0006821) |
0.1 | 0.6 | GO:0016180 | snRNA processing(GO:0016180) |
0.1 | 0.4 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
0.1 | 0.3 | GO:0010820 | T cell chemotaxis(GO:0010818) regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820) regulation of lymphocyte chemotaxis(GO:1901623) regulation of lymphocyte migration(GO:2000401) positive regulation of lymphocyte migration(GO:2000403) regulation of T cell migration(GO:2000404) positive regulation of T cell migration(GO:2000406) |
0.1 | 7.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.1 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
0.0 | 1.4 | GO:0060334 | regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
0.0 | 3.3 | GO:0030183 | B cell differentiation(GO:0030183) |
0.0 | 0.5 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
0.0 | 0.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
0.0 | 4.3 | GO:0001890 | placenta development(GO:0001890) |
0.0 | 0.2 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.0 | 0.1 | GO:1902803 | regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300) |
0.0 | 1.4 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
0.0 | 0.4 | GO:0070301 | cellular response to hydrogen peroxide(GO:0070301) |
0.0 | 0.9 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077) |
0.0 | 0.2 | GO:0000103 | sulfate assimilation(GO:0000103) |
0.0 | 6.4 | GO:0008544 | epidermis development(GO:0008544) |
0.0 | 0.2 | GO:0043316 | natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320) |
0.0 | 0.2 | GO:0010766 | negative regulation of sodium ion transport(GO:0010766) |
0.0 | 1.2 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.1 | GO:0046015 | carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015) |
0.0 | 0.2 | GO:0048073 | regulation of eye pigmentation(GO:0048073) |
0.0 | 0.1 | GO:0009886 | post-embryonic morphogenesis(GO:0009886) |
0.0 | 0.2 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
0.0 | 0.1 | GO:0040034 | regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505) lung-associated mesenchyme development(GO:0060484) |
0.0 | 4.6 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
0.0 | 0.2 | GO:0006562 | proline catabolic process(GO:0006562) |
0.0 | 0.1 | GO:0002024 | diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845) |
0.0 | 0.1 | GO:1904742 | regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381) regulation of telomeric DNA binding(GO:1904742) positive regulation of telomeric DNA binding(GO:1904744) |
0.0 | 0.1 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) positive regulation of transmission of nerve impulse(GO:0051971) |
0.0 | 0.1 | GO:0045767 | obsolete regulation of anti-apoptosis(GO:0045767) |
0.0 | 0.1 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
0.0 | 0.4 | GO:0006449 | regulation of translational termination(GO:0006449) |
0.0 | 0.5 | GO:0006939 | smooth muscle contraction(GO:0006939) |
0.0 | 0.1 | GO:0070989 | oxidative demethylation(GO:0070989) |
0.0 | 0.2 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.0 | 0.1 | GO:1903961 | positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961) |
0.0 | 0.3 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.2 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
0.0 | 0.0 | GO:0072074 | kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075) |
0.0 | 0.2 | GO:0006188 | IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040) |
0.0 | 0.3 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 0.1 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
0.0 | 0.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.5 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.2 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
0.0 | 0.1 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.0 | 0.0 | GO:0006590 | thyroid hormone generation(GO:0006590) |
0.0 | 0.4 | GO:0098602 | single organism cell adhesion(GO:0098602) |
0.0 | 0.1 | GO:0018352 | glutamate decarboxylation to succinate(GO:0006540) protein-pyridoxal-5-phosphate linkage(GO:0018352) |
0.0 | 0.0 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
0.0 | 0.1 | GO:0070588 | calcium ion transmembrane transport(GO:0070588) |
0.0 | 0.1 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 0.1 | GO:0007635 | chemosensory behavior(GO:0007635) |
0.0 | 0.4 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
0.0 | 0.2 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
0.0 | 0.4 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.0 | 1.4 | GO:0072164 | ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164) |
0.0 | 0.4 | GO:0007405 | neuroblast proliferation(GO:0007405) |
0.0 | 0.0 | GO:0043628 | ncRNA 3'-end processing(GO:0043628) |
0.0 | 0.8 | GO:0006903 | vesicle targeting(GO:0006903) |
0.0 | 0.1 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
0.0 | 0.3 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 0.3 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
0.0 | 0.3 | GO:0002076 | osteoblast development(GO:0002076) |
0.0 | 2.9 | GO:0006184 | obsolete GTP catabolic process(GO:0006184) |
0.0 | 0.0 | GO:0060969 | regulation of chromatin silencing(GO:0031935) negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969) |
0.0 | 0.1 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
0.0 | 0.1 | GO:0048645 | organ formation(GO:0048645) |
0.0 | 0.1 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
0.0 | 3.1 | GO:0006417 | regulation of translation(GO:0006417) |
0.0 | 0.2 | GO:0007128 | meiotic prophase I(GO:0007128) male meiosis I(GO:0007141) |
0.0 | 0.1 | GO:0009396 | folic acid-containing compound biosynthetic process(GO:0009396) |
0.0 | 0.1 | GO:0017014 | protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119) |
0.0 | 0.0 | GO:0060534 | trachea cartilage development(GO:0060534) |
0.0 | 0.1 | GO:0006642 | triglyceride mobilization(GO:0006642) |
0.0 | 0.1 | GO:0034243 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
0.0 | 0.2 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
0.0 | 0.4 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
0.0 | 0.1 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
0.0 | 0.1 | GO:0042749 | circadian sleep/wake cycle process(GO:0022410) regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) circadian sleep/wake cycle, sleep(GO:0050802) |
0.0 | 2.1 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
0.0 | 0.1 | GO:0048296 | isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298) |
0.0 | 0.1 | GO:0043248 | proteasome assembly(GO:0043248) |
0.0 | 0.4 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 0.1 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
0.0 | 0.3 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
0.0 | 0.2 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278) |
0.0 | 0.1 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
0.0 | 0.0 | GO:0003077 | obsolete negative regulation of diuresis(GO:0003077) |
0.0 | 0.6 | GO:0061025 | membrane fusion(GO:0061025) |
0.0 | 0.0 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.0 | 0.1 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.3 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.2 | GO:0018214 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
0.0 | 0.1 | GO:0015853 | adenine transport(GO:0015853) |
0.0 | 0.1 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.9 | GO:0005916 | fascia adherens(GO:0005916) |
0.3 | 4.3 | GO:0005922 | connexon complex(GO:0005922) |
0.3 | 6.1 | GO:0030057 | desmosome(GO:0030057) |
0.2 | 1.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.2 | 0.9 | GO:0070695 | FHF complex(GO:0070695) |
0.2 | 0.8 | GO:0033269 | internode region of axon(GO:0033269) |
0.2 | 0.8 | GO:0016342 | catenin complex(GO:0016342) |
0.2 | 1.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
0.2 | 0.9 | GO:0002080 | acrosomal membrane(GO:0002080) |
0.2 | 0.7 | GO:0043259 | laminin-10 complex(GO:0043259) |
0.1 | 5.7 | GO:0045095 | keratin filament(GO:0045095) |
0.1 | 2.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 4.9 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.1 | 5.7 | GO:0005882 | intermediate filament(GO:0005882) |
0.1 | 0.6 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.1 | 2.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.1 | 0.8 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.1 | 1.0 | GO:0031143 | pseudopodium(GO:0031143) |
0.1 | 0.7 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
0.1 | 1.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.1 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.1 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
0.0 | 3.7 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 1.5 | GO:0098636 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.2 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 1.2 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
0.0 | 0.7 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.7 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.7 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.4 | GO:0042627 | chylomicron(GO:0042627) |
0.0 | 0.3 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
0.0 | 0.1 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
0.0 | 1.3 | GO:0005624 | obsolete membrane fraction(GO:0005624) |
0.0 | 0.2 | GO:0000242 | pericentriolar material(GO:0000242) |
0.0 | 0.1 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 1.4 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
0.0 | 1.0 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
0.0 | 0.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562) |
0.0 | 2.1 | GO:0005795 | Golgi stack(GO:0005795) |
0.0 | 0.1 | GO:0031672 | A band(GO:0031672) |
0.0 | 0.2 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.1 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.0 | 0.2 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.1 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 0.8 | GO:0005911 | cell-cell junction(GO:0005911) |
0.0 | 0.1 | GO:0019815 | immunoglobulin complex(GO:0019814) B cell receptor complex(GO:0019815) |
0.0 | 0.2 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.2 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.9 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.8 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 0.2 | GO:0000299 | obsolete integral to membrane of membrane fraction(GO:0000299) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.1 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
0.4 | 1.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.4 | 1.1 | GO:0008970 | phosphatidylcholine 1-acylhydrolase activity(GO:0008970) |
0.4 | 4.3 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.3 | 0.9 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
0.2 | 1.2 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
0.2 | 0.6 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
0.2 | 1.0 | GO:0004910 | interleukin-1, Type II, blocking receptor activity(GO:0004910) |
0.2 | 1.6 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
0.2 | 0.7 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
0.2 | 0.7 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
0.2 | 0.5 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.2 | 0.9 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.7 | GO:0005499 | vitamin D binding(GO:0005499) |
0.1 | 0.6 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
0.1 | 0.6 | GO:0008184 | purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184) |
0.1 | 4.5 | GO:0051117 | ATPase binding(GO:0051117) |
0.1 | 1.0 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.1 | 1.1 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
0.1 | 0.7 | GO:0032190 | acrosin binding(GO:0032190) |
0.1 | 0.3 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.1 | 1.2 | GO:0050780 | dopamine receptor binding(GO:0050780) |
0.1 | 0.3 | GO:0008431 | vitamin E binding(GO:0008431) |
0.1 | 0.8 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 0.3 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
0.1 | 1.0 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
0.1 | 0.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.1 | 0.5 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.1 | 0.2 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859) |
0.1 | 8.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.1 | 0.3 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.1 | 0.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 0.5 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
0.1 | 0.2 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
0.1 | 1.5 | GO:0043498 | obsolete cell surface binding(GO:0043498) |
0.1 | 0.2 | GO:0015217 | purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217) |
0.1 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.1 | 0.4 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.1 | 0.2 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.1 | 0.5 | GO:1901567 | icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567) |
0.1 | 5.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 0.4 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.1 | 3.1 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.1 | 0.4 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
0.1 | 0.4 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.1 | 0.8 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
0.1 | 0.4 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.0 | 0.1 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
0.0 | 0.2 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 0.8 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
0.0 | 0.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.1 | GO:0003978 | UDP-glucose 4-epimerase activity(GO:0003978) |
0.0 | 0.2 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
0.0 | 0.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 0.5 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.0 | 0.2 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
0.0 | 0.7 | GO:0015101 | organic cation transmembrane transporter activity(GO:0015101) |
0.0 | 0.2 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
0.0 | 0.1 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.3 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.5 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.0 | 0.1 | GO:0031877 | somatostatin receptor binding(GO:0031877) |
0.0 | 0.1 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.0 | 0.4 | GO:0015355 | secondary active monocarboxylate transmembrane transporter activity(GO:0015355) |
0.0 | 0.1 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.3 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.0 | 0.1 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.0 | 0.1 | GO:0030156 | benzodiazepine receptor binding(GO:0030156) |
0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.1 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.0 | 0.2 | GO:0005113 | patched binding(GO:0005113) |
0.0 | 0.3 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 0.3 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.0 | 0.2 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.3 | GO:0047035 | testosterone dehydrogenase (NAD+) activity(GO:0047035) |
0.0 | 0.1 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
0.0 | 0.1 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
0.0 | 0.2 | GO:0051766 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766) |
0.0 | 0.4 | GO:0016780 | phosphotransferase activity, for other substituted phosphate groups(GO:0016780) |
0.0 | 0.5 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.0 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
0.0 | 0.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.1 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
0.0 | 0.1 | GO:0016724 | ferroxidase activity(GO:0004322) metallochaperone activity(GO:0016530) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
0.0 | 0.1 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.0 | 0.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.1 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
0.0 | 0.2 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 2.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.4 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
0.0 | 0.6 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.0 | 0.1 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.0 | 0.1 | GO:0005174 | CD40 receptor binding(GO:0005174) |
0.0 | 0.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
0.0 | 0.1 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.0 | 0.3 | GO:0050786 | RAGE receptor binding(GO:0050786) |
0.0 | 0.1 | GO:0017040 | ceramidase activity(GO:0017040) |
0.0 | 0.2 | GO:0031419 | cobalamin binding(GO:0031419) |
0.0 | 0.1 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
0.0 | 0.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.0 | 0.3 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 0.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
0.0 | 0.1 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.1 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
0.0 | 1.1 | GO:0030165 | PDZ domain binding(GO:0030165) |
0.0 | 0.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.0 | 0.1 | GO:0047631 | ADP-ribose diphosphatase activity(GO:0047631) |
0.0 | 0.2 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
0.0 | 0.3 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.2 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.0 | 0.1 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 1.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
0.0 | 0.1 | GO:0004448 | isocitrate dehydrogenase activity(GO:0004448) |
0.0 | 1.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
0.0 | 0.1 | GO:0003785 | actin monomer binding(GO:0003785) |
0.0 | 0.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.3 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 0.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.1 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
0.0 | 0.1 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.0 | 0.1 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
0.0 | 0.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
0.0 | 0.1 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.0 | 0.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.2 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.1 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.1 | GO:0005345 | purine nucleobase transmembrane transporter activity(GO:0005345) |
0.0 | 0.1 | GO:0008527 | taste receptor activity(GO:0008527) |
0.0 | 1.0 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.5 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.6 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 1.1 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 0.1 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |