Motif ID: UAAGACU

Z-value: 0.407


Mature miRNA associated with seed UAAGACU:

NamemiRBase Accession
hsa-miR-499a-5p MIMAT0002870



Activity profile for motif UAAGACU.

activity profile for motif UAAGACU


Sorted Z-values histogram for motif UAAGACU

Sorted Z-values for motif UAAGACU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAGACU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_38614807 0.460 ENST00000330691.6
ENST00000348567.4
 TACC1

transforming, acidic coiled-coil containing protein 1

chr19_-_7293942 0.259 ENST00000341500.5
ENST00000302850.5
 INSR

insulin receptor

chr1_-_154842741 0.208 ENST00000271915.4
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr8_+_56014949 0.207 ENST00000327381.6
 XKR4
XK, Kell blood group complex subunit-related family, member 4
chr10_+_112631547 0.189 ENST00000280154.7
ENST00000393104.2
 PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr7_-_120498357 0.184 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
 TSPAN12


tetraspanin 12


chr5_+_112312416 0.171 ENST00000389063.2
 DCP2
decapping mRNA 2
chr17_+_58677539 0.168 ENST00000305921.3
 PPM1D
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr2_-_64881018 0.166 ENST00000313349.3
 SERTAD2
SERTA domain containing 2
chr3_+_186501336 0.162 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
 EIF4A2


eukaryotic translation initiation factor 4A2


chr6_-_99797522 0.149 ENST00000389677.5
 FAXC
failed axon connections homolog (Drosophila)
chr16_-_46655538 0.137 ENST00000303383.3
 SHCBP1
SHC SH2-domain binding protein 1
chrY_+_15016725 0.136 ENST00000336079.3
 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_72496035 0.107 ENST00000477973.2
 RYBP
RING1 and YY1 binding protein
chr7_-_139876812 0.105 ENST00000397560.2
 JHDM1D
lysine (K)-specific demethylase 7A
chr10_+_63661053 0.102 ENST00000279873.7
 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr3_+_43328004 0.082 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
 SNRK



SNF related kinase



chr5_-_76788317 0.081 ENST00000296679.4
 WDR41
WD repeat domain 41
chr1_+_145611010 0.080 ENST00000369291.5
 RNF115
ring finger protein 115
chr1_-_16678914 0.078 ENST00000375592.3
 FBXO42
F-box protein 42
chr2_+_228029281 0.077 ENST00000396578.3
 COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr2_-_86564776 0.076 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
 REEP1


receptor accessory protein 1


chr8_+_58907104 0.075 ENST00000361488.3
 FAM110B
family with sequence similarity 110, member B
chr12_+_72148614 0.074 ENST00000261263.3
 RAB21
RAB21, member RAS oncogene family
chr17_-_60142609 0.074 ENST00000397786.2
 MED13
mediator complex subunit 13
chr3_-_15374033 0.068 ENST00000253688.5
ENST00000383791.3
 SH3BP5

SH3-domain binding protein 5 (BTK-associated)

chr2_+_42396472 0.067 ENST00000318522.5
ENST00000402711.2
 EML4

echinoderm microtubule associated protein like 4

chr15_-_49338748 0.065 ENST00000559471.1
 SECISBP2L
SECIS binding protein 2-like
chr10_-_27149792 0.063 ENST00000376140.3
ENST00000376170.4
 ABI1

abl-interactor 1

chr11_-_86666427 0.062 ENST00000531380.1
 FZD4
frizzled family receptor 4
chr12_+_68042495 0.061 ENST00000344096.3
 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr7_+_90225796 0.061 ENST00000380050.3
 CDK14
cyclin-dependent kinase 14
chr12_-_12419703 0.060 ENST00000543091.1
ENST00000261349.4
 LRP6

low density lipoprotein receptor-related protein 6

chr1_+_97187318 0.057 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
 PTBP2




polypyrimidine tract binding protein 2




chr8_+_42752053 0.056 ENST00000307602.4
 HOOK3
hook microtubule-tethering protein 3
chr2_-_68290106 0.052 ENST00000407324.1
ENST00000355848.3
ENST00000409302.1
ENST00000410067.3
 C1D



C1D nuclear receptor corepressor



chr6_+_72596604 0.051 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
 RIMS1






regulating synaptic membrane exocytosis 1






chr17_+_29718642 0.050 ENST00000325874.8
 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr14_-_50698276 0.049 ENST00000216373.5
 SOS2
son of sevenless homolog 2 (Drosophila)
chr8_+_11561660 0.049 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
 GATA4


GATA binding protein 4


chr17_+_66508537 0.049 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
 PRKAR1A





protein kinase, cAMP-dependent, regulatory, type I, alpha





chr1_+_36396677 0.049 ENST00000373191.4
ENST00000397828.2
 AGO3

argonaute RISC catalytic component 3

chr22_+_21771656 0.048 ENST00000407464.2
 HIC2
hypermethylated in cancer 2
chr1_-_39339777 0.048 ENST00000397572.2
 MYCBP
MYC binding protein
chr5_+_161274685 0.047 ENST00000428797.2
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_122110691 0.045 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
 SNX2


sorting nexin 2


chr2_+_120517174 0.045 ENST00000263708.2
 PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr15_+_57210818 0.044 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
 TCF12




transcription factor 12




chr15_-_64648273 0.041 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
 CSNK1G1


casein kinase 1, gamma 1


chr1_+_50574585 0.041 ENST00000371824.1
ENST00000371823.4
 ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr6_-_13711773 0.038 ENST00000011619.3
 RANBP9
RAN binding protein 9
chr3_+_29322803 0.037 ENST00000396583.3
ENST00000383767.2
 RBMS3

RNA binding motif, single stranded interacting protein 3

chr17_-_45266542 0.037 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
 CDC27




cell division cycle 27




chrX_+_16737718 0.037 ENST00000380155.3
 SYAP1
synapse associated protein 1
chr5_-_114880533 0.032 ENST00000274457.3
 FEM1C
fem-1 homolog c (C. elegans)
chrX_+_41192595 0.032 ENST00000399959.2
 DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr11_-_128392085 0.029 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
 ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr12_-_42538657 0.028 ENST00000398675.3
 GXYLT1
glucoside xylosyltransferase 1
chr9_-_19786926 0.028 ENST00000341998.2
ENST00000286344.3
 SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr6_-_166075557 0.027 ENST00000539869.2
ENST00000366882.1
 PDE10A

phosphodiesterase 10A

chr15_+_101142722 0.025 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
 ASB7


ankyrin repeat and SOCS box containing 7


chr15_+_44829255 0.024 ENST00000261868.5
ENST00000424492.3
 EIF3J

eukaryotic translation initiation factor 3, subunit J

chr17_-_48785216 0.024 ENST00000285243.6
 ANKRD40
ankyrin repeat domain 40
chr7_+_65338230 0.023 ENST00000360768.3
 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr1_-_39347255 0.021 ENST00000454994.2
ENST00000357771.3
 GJA9

gap junction protein, alpha 9, 59kDa

chr2_+_176981307 0.021 ENST00000249501.4
 HOXD10
homeobox D10
chr13_+_49550015 0.021 ENST00000492622.2
 FNDC3A
fibronectin type III domain containing 3A
chr9_-_23821273 0.020 ENST00000380110.4
 ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr7_+_138916231 0.019 ENST00000473989.3
ENST00000288561.8
 UBN2

ubinuclein 2

chr1_-_21113105 0.018 ENST00000375000.1
ENST00000419490.1
ENST00000414993.1
ENST00000443615.1
ENST00000312239.5
 HP1BP3




heterochromatin protein 1, binding protein 3




chr6_+_163835669 0.018 ENST00000453779.2
ENST00000275262.7
ENST00000392127.2
ENST00000361752.3
 QKI



QKI, KH domain containing, RNA binding



chr13_+_102104980 0.018 ENST00000545560.2
 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr14_+_105781048 0.018 ENST00000458164.2
ENST00000447393.1
 PACS2

phosphofurin acidic cluster sorting protein 2

chr7_-_44924939 0.017 ENST00000395699.2
 PURB
purine-rich element binding protein B
chr6_+_133562472 0.016 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
 EYA4



eyes absent homolog 4 (Drosophila)



chr4_+_139936905 0.015 ENST00000280614.2
 CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr3_-_15563229 0.014 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
 COLQ




collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase




chr9_+_82186872 0.012 ENST00000376544.3
ENST00000376520.4
 TLE4

transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)

chr13_+_50571155 0.010 ENST00000420995.2
ENST00000378182.3
ENST00000356017.4
ENST00000457662.2
 TRIM13



tripartite motif containing 13



chr8_-_89339705 0.008 ENST00000286614.6
 MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr3_+_89156674 0.006 ENST00000336596.2
 EPHA3
EPH receptor A3
chr1_+_43148059 0.006 ENST00000321358.7
ENST00000332220.6
 YBX1

Y box binding protein 1

chr6_+_37225540 0.005 ENST00000373491.3
 TBC1D22B
TBC1 domain family, member 22B
chr2_+_176987088 0.005 ENST00000249499.6
 HOXD9
homeobox D9
chr5_-_79287060 0.004 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
 MTX3


metaxin 3


chr4_+_123747834 0.004 ENST00000264498.3
 FGF2
fibroblast growth factor 2 (basic)
chr2_-_131850951 0.002 ENST00000409185.1
ENST00000389915.3
 FAM168B

family with sequence similarity 168, member B

chr21_-_16437255 0.002 ENST00000400199.1
ENST00000400202.1
 NRIP1

nuclear receptor interacting protein 1

chr15_-_56535464 0.002 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
 RFX7



regulatory factor X, 7



chr14_-_61116168 0.002 ENST00000247182.6
 SIX1
SIX homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060267 transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:2000051 pericardium morphogenesis(GO:0003344) post-embryonic appendage morphogenesis(GO:0035120) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536) mammary placode formation(GO:0060596) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:0003289 septum primum development(GO:0003284) atrial septum primum morphogenesis(GO:0003289) intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)