Motif ID: UACAGUA
Z-value: 1.189
Mature miRNA associated with seed UACAGUA:
Name | miRBase Accession |
---|---|
hsa-miR-101-3p.2 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.5 | 4.3 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.5 | 1.4 | GO:0008218 | bioluminescence(GO:0008218) |
0.5 | 1.8 | GO:0051503 | purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) |
0.4 | 1.4 | GO:0010761 | fibroblast migration(GO:0010761) |
0.3 | 0.8 | GO:0090047 | obsolete positive regulation of transcription regulator activity(GO:0090047) |
0.3 | 0.8 | GO:0048681 | negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571) |
0.2 | 1.0 | GO:0043128 | regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128) |
0.2 | 1.2 | GO:0048669 | collateral sprouting in absence of injury(GO:0048669) |
0.2 | 0.7 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
0.2 | 1.0 | GO:0044854 | membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) positive regulation of dopamine receptor signaling pathway(GO:0060161) caveola assembly(GO:0070836) membrane assembly(GO:0071709) |
0.2 | 0.5 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
0.2 | 0.6 | GO:0031394 | cyclooxygenase pathway(GO:0019371) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280) |
0.2 | 0.5 | GO:0002887 | negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) establishment of epithelial cell apical/basal polarity(GO:0045198) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
0.1 | 0.8 | GO:0032926 | negative regulation of gonadotropin secretion(GO:0032277) negative regulation of activin receptor signaling pathway(GO:0032926) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
0.1 | 0.7 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
0.1 | 0.4 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
0.1 | 0.5 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
0.1 | 0.6 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.1 | 0.6 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.1 | 0.5 | GO:0010842 | retina layer formation(GO:0010842) |
0.1 | 0.2 | GO:0048289 | isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293) |
0.1 | 1.2 | GO:0001945 | lymph vessel development(GO:0001945) |
0.1 | 0.3 | GO:0034959 | neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
0.1 | 0.2 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
0.1 | 0.4 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.1 | 0.5 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.1 | 0.3 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 0.2 | GO:0018243 | protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243) |
0.1 | 0.2 | GO:0046469 | layer formation in cerebral cortex(GO:0021819) platelet activating factor metabolic process(GO:0046469) |
0.1 | 0.3 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
0.1 | 0.1 | GO:0060297 | regulation of sarcomere organization(GO:0060297) |
0.1 | 0.2 | GO:0014742 | positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742) |
0.1 | 0.6 | GO:0001706 | endoderm formation(GO:0001706) |
0.1 | 0.5 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
0.1 | 0.4 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.8 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.1 | 0.2 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.0 | 0.3 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
0.0 | 0.1 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.1 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
0.0 | 0.1 | GO:0060128 | corticotropin hormone secreting cell differentiation(GO:0060128) |
0.0 | 0.9 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
0.0 | 0.3 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
0.0 | 0.1 | GO:0001999 | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) |
0.0 | 0.3 | GO:0048630 | skeletal muscle tissue growth(GO:0048630) |
0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
0.0 | 0.3 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.0 | 0.7 | GO:0001953 | negative regulation of cell-matrix adhesion(GO:0001953) |
0.0 | 0.2 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
0.0 | 0.1 | GO:0070933 | histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933) |
0.0 | 0.1 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.0 | 0.2 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
0.0 | 0.1 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
0.0 | 0.3 | GO:0006465 | signal peptide processing(GO:0006465) |
0.0 | 0.1 | GO:0007028 | cytoplasm organization(GO:0007028) |
0.0 | 0.3 | GO:0031290 | retinal ganglion cell axon guidance(GO:0031290) |
0.0 | 0.5 | GO:0008347 | glial cell migration(GO:0008347) |
0.0 | 0.5 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 0.2 | GO:0033522 | histone H2A ubiquitination(GO:0033522) |
0.0 | 0.0 | GO:0048875 | surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875) |
0.0 | 0.2 | GO:0008354 | germ cell migration(GO:0008354) |
0.0 | 0.8 | GO:0002208 | somatic recombination of immunoglobulin genes involved in immune response(GO:0002204) somatic diversification of immunoglobulins involved in immune response(GO:0002208) isotype switching(GO:0045190) |
0.0 | 0.1 | GO:0010452 | histone H3-K36 methylation(GO:0010452) |
0.0 | 0.4 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.1 | GO:0019985 | translesion synthesis(GO:0019985) |
0.0 | 0.4 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.1 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393) |
0.0 | 0.1 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.0 | 0.2 | GO:0014044 | Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
0.0 | 0.2 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
0.0 | 0.9 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
0.0 | 0.3 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.0 | 0.6 | GO:0021987 | cerebral cortex development(GO:0021987) |
0.0 | 0.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.2 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.0 | 0.3 | GO:0006071 | glycerol metabolic process(GO:0006071) |
0.0 | 0.1 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.1 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.0 | 0.1 | GO:0043044 | ATP-dependent chromatin remodeling(GO:0043044) |
0.0 | 0.0 | GO:0033025 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
0.0 | 0.6 | GO:0001843 | neural tube closure(GO:0001843) tube closure(GO:0060606) |
0.0 | 1.1 | GO:0008360 | regulation of cell shape(GO:0008360) |
0.0 | 0.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.0 | 0.0 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 4.3 | GO:0001527 | microfibril(GO:0001527) |
0.3 | 3.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.2 | 0.7 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.2 | 1.2 | GO:0051233 | spindle midzone(GO:0051233) |
0.2 | 1.8 | GO:0005916 | fascia adherens(GO:0005916) |
0.1 | 0.4 | GO:0005955 | calcineurin complex(GO:0005955) |
0.1 | 0.3 | GO:0005787 | signal peptidase complex(GO:0005787) |
0.1 | 0.6 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.1 | 0.3 | GO:0031310 | intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310) |
0.1 | 0.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.1 | 0.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.1 | 0.5 | GO:0042598 | obsolete vesicular fraction(GO:0042598) |
0.0 | 0.2 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.3 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
0.0 | 0.8 | GO:0032589 | neuron projection membrane(GO:0032589) |
0.0 | 1.0 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.2 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.0 | 0.1 | GO:1990752 | microtubule plus-end(GO:0035371) microtubule end(GO:1990752) |
0.0 | 0.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 1.1 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.5 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.0 | 0.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
0.0 | 0.1 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.0 | 1.3 | GO:0005604 | basement membrane(GO:0005604) |
0.0 | 0.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 0.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.6 | GO:0030133 | transport vesicle(GO:0030133) |
0.0 | 0.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.3 | GO:0005902 | microvillus(GO:0005902) |
0.0 | 0.8 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 1.0 | GO:0016459 | myosin complex(GO:0016459) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:0070052 | collagen V binding(GO:0070052) |
0.3 | 0.8 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.2 | 2.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.2 | 0.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.2 | 0.7 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.2 | 0.6 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.2 | 1.8 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.1 | 1.2 | GO:0051425 | PTB domain binding(GO:0051425) |
0.1 | 0.4 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) ciliary neurotrophic factor receptor binding(GO:0005127) |
0.1 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.1 | 0.5 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.1 | 1.0 | GO:0050780 | dopamine receptor binding(GO:0050780) |
0.1 | 1.1 | GO:0004065 | arylsulfatase activity(GO:0004065) |
0.1 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.1 | 0.2 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
0.1 | 0.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.3 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 0.7 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) |
0.1 | 1.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.1 | 0.3 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
0.0 | 0.6 | GO:0042301 | phosphate ion binding(GO:0042301) |
0.0 | 0.2 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.0 | 0.1 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
0.0 | 4.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.0 | 0.7 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.9 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.7 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.1 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
0.0 | 0.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.2 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.6 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.0 | 0.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) bicarbonate transmembrane transporter activity(GO:0015106) |
0.0 | 0.4 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.1 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
0.0 | 0.3 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.0 | 0.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.1 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) |
0.0 | 0.1 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
0.0 | 0.3 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.1 | GO:0004835 | tubulin-tyrosine ligase activity(GO:0004835) |
0.0 | 0.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.0 | 0.2 | GO:0033612 | receptor serine/threonine kinase binding(GO:0033612) |
0.0 | 0.1 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
0.0 | 1.1 | GO:0051287 | NAD binding(GO:0051287) |
0.0 | 0.2 | GO:0003706 | obsolete ligand-regulated transcription factor activity(GO:0003706) |
0.0 | 0.1 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.0 | GO:0044325 | ion channel binding(GO:0044325) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.0 | GO:0008502 | melatonin receptor activity(GO:0008502) |
0.0 | 0.4 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.1 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.0 | 0.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
0.0 | 0.0 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
0.0 | 0.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.6 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
0.0 | 0.1 | GO:0031078 | NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H3-K9 specific)(GO:0032129) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent protein deacetylase activity(GO:0034979) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.7 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.5 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
0.0 | 1.6 | SIG_BCR_SIGNALING_PATHWAY | Members of the BCR signaling pathway |
0.0 | 0.6 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |