Motif ID: UCCAGUU

Z-value: 1.535


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145-5p MIMAT0000437
hsa-miR-5195-3p MIMAT0021127



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_131241361 3.156 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr6_+_151561085 2.734 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr7_+_130126012 2.344 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_+_86046433 2.157 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr15_-_52821247 2.039 ENST00000399231.3
ENST00000399233.2
MYO5A

myosin VA (heavy chain 12, myoxin)

chr7_+_100770328 2.027 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chrX_-_99891796 1.901 ENST00000373020.4
TSPAN6
tetraspanin 6
chr2_+_36582857 1.831 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr8_+_26435359 1.821 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr1_+_186798073 1.723 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr4_+_146402925 1.706 ENST00000302085.4
SMAD1
SMAD family member 1
chr8_-_6420930 1.627 ENST00000325203.5
ANGPT2
angiopoietin 2
chr5_-_39425068 1.590 ENST00000515700.1
ENST00000339788.6
DAB2

Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)

chr2_+_9346892 1.494 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr3_+_30648066 1.490 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr6_+_76458909 1.241 ENST00000369981.3
ENST00000369985.4
MYO6

myosin VI

chr20_-_4804244 1.179 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_+_101702417 1.173 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr5_+_86564739 1.162 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1


RAS p21 protein activator (GTPase activating protein) 1


chr18_-_53255766 1.127 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr4_-_102268628 1.119 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr21_-_28338732 1.109 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr9_-_14314066 1.076 ENST00000397575.3
NFIB
nuclear factor I/B
chr5_-_157002775 1.047 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr7_+_114562172 1.047 ENST00000393486.1
ENST00000257724.3
MDFIC

MyoD family inhibitor domain containing

chr20_+_19867150 1.032 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr1_-_21671968 1.023 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr19_+_16187085 1.006 ENST00000300933.4
TPM4
tropomyosin 4
chr1_-_94703118 0.996 ENST00000260526.6
ENST00000370217.3
ARHGAP29

Rho GTPase activating protein 29

chr1_-_208417620 0.994 ENST00000367033.3
PLXNA2
plexin A2
chr11_+_9685604 0.984 ENST00000447399.2
ENST00000318950.6
SWAP70

SWAP switching B-cell complex 70kDa subunit

chr3_-_134093395 0.950 ENST00000249883.5
AMOTL2
angiomotin like 2
chr5_-_121413974 0.943 ENST00000231004.4
LOX
lysyl oxidase
chr7_-_27183263 0.925 ENST00000222726.3
HOXA5
homeobox A5
chr6_-_116575226 0.923 ENST00000420283.1
TSPYL4
TSPY-like 4
chr13_-_41240717 0.869 ENST00000379561.5
FOXO1
forkhead box O1
chr14_-_20020272 0.843 ENST00000551509.1
POTEM
POTE ankyrin domain family, member M
chr16_+_69221028 0.842 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_+_116139424 0.813 ENST00000222693.4
CAV2
caveolin 2
chr13_-_29069232 0.813 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1


fms-related tyrosine kinase 1


chr3_+_110790590 0.802 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr4_+_86396265 0.793 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr3_-_114790179 0.785 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_92539614 0.756 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr12_+_27396901 0.754 ENST00000541191.1
ENST00000389032.3
STK38L

serine/threonine kinase 38 like

chr4_+_78078304 0.745 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2


cyclin G2


chr14_+_19553365 0.742 ENST00000409832.3
POTEG
POTE ankyrin domain family, member G
chr21_-_39870339 0.666 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chr6_-_11232891 0.664 ENST00000379433.5
ENST00000379446.5
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr13_-_72441315 0.630 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1


dachshund homolog 1 (Drosophila)


chr17_-_46682321 0.628 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr13_+_73632897 0.624 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr19_+_34745442 0.623 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355



KIAA0355



chr6_+_143929307 0.622 ENST00000427704.2
ENST00000305766.6
PHACTR2

phosphatase and actin regulator 2

chr7_+_69064300 0.593 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr12_+_58087901 0.588 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9









osteosarcoma amplified 9, endoplasmic reticulum lectin









chr12_+_96588143 0.583 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr5_-_77844974 0.579 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr11_+_128563652 0.578 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_86666427 0.563 ENST00000531380.1
FZD4
frizzled family receptor 4
chr1_+_200708671 0.550 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr2_+_148602058 0.542 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A


activin A receptor, type IIA


chr22_-_38902325 0.533 ENST00000396821.3
ENST00000381633.3
DDX17

DEAD (Asp-Glu-Ala-Asp) box helicase 17

chr2_+_5832799 0.511 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr15_+_63569731 0.506 ENST00000261879.5
APH1B
APH1B gamma secretase subunit
chr4_-_25864581 0.499 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr3_+_57994127 0.477 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
FLNB





filamin B, beta





chr9_+_128509624 0.470 ENST00000342287.5
ENST00000373487.4
PBX3

pre-B-cell leukemia homeobox 3

chr21_-_39288743 0.468 ENST00000609713.1
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr15_-_93199069 0.465 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr3_+_171758344 0.447 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr3_+_179370517 0.443 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr17_+_46125707 0.435 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr12_+_111843749 0.423 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr1_+_155099927 0.422 ENST00000368407.3
EFNA1
ephrin-A1
chr3_-_129325660 0.420 ENST00000324093.4
ENST00000393239.1
PLXND1

plexin D1

chr18_+_3247413 0.412 ENST00000579226.1
ENST00000217652.3
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr17_-_5389477 0.412 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2



derlin 2



chr3_-_189838670 0.408 ENST00000319332.5
LEPREL1
leprecan-like 1
chr8_-_18871159 0.403 ENST00000327040.8
ENST00000440756.2
PSD3

pleckstrin and Sec7 domain containing 3

chr2_+_110551851 0.402 ENST00000272454.6
ENST00000430736.1
ENST00000016946.3
ENST00000441344.1
RGPD5



RANBP2-like and GRIP domain containing 5



chr3_-_11762202 0.397 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4


vestigial like 4 (Drosophila)


chr15_+_67358163 0.396 ENST00000327367.4
SMAD3
SMAD family member 3
chr2_+_108443388 0.396 ENST00000354986.4
ENST00000408999.3
RGPD4

RANBP2-like and GRIP domain containing 4

chrX_-_77041685 0.384 ENST00000373344.5
ENST00000395603.3
ATRX

alpha thalassemia/mental retardation syndrome X-linked

chr1_+_218519577 0.383 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chr17_-_79479789 0.379 ENST00000571691.1
ENST00000571721.1
ENST00000573283.1
ENST00000575842.1
ENST00000575087.1
ENST00000570382.1
ENST00000331925.2
ACTG1






actin, gamma 1






chr3_+_57261743 0.366 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chrX_+_73641286 0.354 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr14_+_67707826 0.330 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr3_+_98451275 0.321 ENST00000265261.6
ENST00000497008.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr6_+_71122974 0.319 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chrX_+_48432892 0.313 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr3_+_173116225 0.308 ENST00000457714.1
NLGN1
neuroligin 1
chr3_+_69134080 0.298 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr14_-_23388338 0.297 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23














RNA binding motif protein 23














chr20_-_25566153 0.296 ENST00000278886.6
ENST00000422516.1
NINL

ninein-like

chr9_-_95896550 0.296 ENST00000375446.4
NINJ1
ninjurin 1
chr2_-_216300784 0.295 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1













fibronectin 1













chr8_-_42751820 0.294 ENST00000526349.1
ENST00000527424.1
ENST00000534961.1
ENST00000319073.4
RNF170



ring finger protein 170



chr12_+_72233487 0.289 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15





TBC1 domain family, member 15





chr17_-_1083078 0.288 ENST00000574266.1
ENST00000302538.5
ABR

active BCR-related

chr17_-_15165854 0.275 ENST00000395936.1
ENST00000395938.2
PMP22

peripheral myelin protein 22

chr17_-_58603568 0.275 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr8_-_119124045 0.269 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr3_+_101504200 0.269 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr18_-_51751132 0.268 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr8_-_27630102 0.264 ENST00000356537.4
ENST00000522915.1
ENST00000539095.1
CCDC25


coiled-coil domain containing 25


chr11_+_61447845 0.262 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr11_-_64570706 0.257 ENST00000294066.2
ENST00000377350.3
MAP4K2

mitogen-activated protein kinase kinase kinase kinase 2

chr3_+_16926441 0.257 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr19_+_39616410 0.249 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr5_+_14143728 0.242 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr11_-_104034827 0.238 ENST00000393158.2
PDGFD
platelet derived growth factor D
chr13_-_99630233 0.237 ENST00000376460.1
ENST00000442173.1
DOCK9

dedicator of cytokinesis 9

chr18_-_18691739 0.236 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr14_-_78083112 0.236 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr12_-_120687948 0.235 ENST00000458477.2
PXN
paxillin
chr13_+_49550015 0.235 ENST00000492622.2
FNDC3A
fibronectin type III domain containing 3A
chr8_+_123793633 0.232 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr7_-_5570229 0.230 ENST00000331789.5
ACTB
actin, beta
chr2_-_111334678 0.228 ENST00000329516.3
ENST00000330331.5
ENST00000446930.1
RGPD6


RANBP2-like and GRIP domain containing 6


chr11_+_57520715 0.226 ENST00000524630.1
ENST00000529919.1
ENST00000399039.4
ENST00000533189.1
CTNND1



catenin (cadherin-associated protein), delta 1



chr1_-_183604794 0.223 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5


actin related protein 2/3 complex, subunit 5, 16kDa


chr18_-_45456930 0.223 ENST00000262160.6
ENST00000587269.1
SMAD2

SMAD family member 2

chr15_-_73076030 0.223 ENST00000311669.8
ADPGK
ADP-dependent glucokinase
chr17_+_61699766 0.215 ENST00000579585.1
ENST00000584573.1
ENST00000361733.3
ENST00000361357.3
MAP3K3



mitogen-activated protein kinase kinase kinase 3



chr20_-_48099182 0.214 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr10_+_82213904 0.202 ENST00000429989.3
TSPAN14
tetraspanin 14
chr2_-_107084826 0.201 ENST00000304514.7
ENST00000409886.3
RGPD3

RANBP2-like and GRIP domain containing 3

chr14_+_50359773 0.201 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr11_-_118966167 0.199 ENST00000530167.1
H2AFX
H2A histone family, member X
chr8_+_95732095 0.196 ENST00000414645.2
DPY19L4
dpy-19-like 4 (C. elegans)
chr4_+_154125565 0.194 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr5_+_115177178 0.191 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr2_-_9695847 0.187 ENST00000310823.3
ENST00000497134.1
ADAM17

ADAM metallopeptidase domain 17

chr10_+_112631547 0.187 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr6_-_111804393 0.186 ENST00000368802.3
ENST00000368805.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chr10_-_118032697 0.184 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr1_+_160313062 0.182 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
NCSTN


nicastrin


chr20_+_1875110 0.177 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr5_+_151151471 0.177 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr19_+_18794470 0.176 ENST00000321949.8
ENST00000338797.6
CRTC1

CREB regulated transcription coactivator 1

chr11_-_118134997 0.175 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr14_-_75179774 0.173 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1


AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1


Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr10_-_74856608 0.172 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr3_-_15901278 0.172 ENST00000399451.2
ANKRD28
ankyrin repeat domain 28
chr3_+_15643245 0.167 ENST00000303498.5
ENST00000437172.1
BTD

biotinidase

chr19_-_11308190 0.164 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2




KN motif and ankyrin repeat domains 2




chr2_-_136288113 0.159 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr3_+_9404526 0.158 ENST00000452837.2
ENST00000417036.1
ENST00000419437.1
ENST00000345094.3
ENST00000515662.2
THUMPD3




THUMP domain containing 3




chr19_-_40324255 0.158 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr11_-_6704513 0.157 ENST00000532203.1
ENST00000288937.6
MRPL17

mitochondrial ribosomal protein L17

chr10_+_111767720 0.155 ENST00000356080.4
ENST00000277900.8
ADD3

adducin 3 (gamma)

chr7_+_77166592 0.155 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr2_-_131267239 0.151 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr17_+_72983674 0.150 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr7_+_5938351 0.149 ENST00000325974.6
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr15_-_34502278 0.148 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1



katanin p80 subunit B-like 1



chr12_-_31744031 0.147 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr10_+_96162242 0.143 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr1_-_185286461 0.139 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr3_-_156877997 0.139 ENST00000295926.3
CCNL1
cyclin L1
chr5_+_140560980 0.136 ENST00000361016.2
PCDHB16
protocadherin beta 16
chr3_-_120461378 0.131 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr12_+_121148228 0.127 ENST00000344651.4
UNC119B
unc-119 homolog B (C. elegans)
chr1_-_170043709 0.125 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
KIFAP3


kinesin-associated protein 3


chr19_+_1269324 0.124 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP










cold inducible RNA binding protein










chr11_-_65381643 0.122 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr7_-_6866401 0.120 ENST00000316731.8
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr5_-_133304473 0.119 ENST00000231512.3
C5orf15
chromosome 5 open reading frame 15
chr6_+_158733692 0.118 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr18_-_21977748 0.115 ENST00000399441.4
ENST00000319481.3
OSBPL1A

oxysterol binding protein-like 1A

chr12_+_49761224 0.114 ENST00000553127.1
ENST00000321898.6
SPATS2

spermatogenesis associated, serine-rich 2

chr9_+_77112244 0.113 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr2_+_136499179 0.112 ENST00000272638.9
UBXN4
UBX domain protein 4
chrX_-_108976521 0.110 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4




acyl-CoA synthetase long-chain family member 4




chr8_-_119964434 0.109 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr12_-_93323013 0.102 ENST00000322349.8
EEA1
early endosome antigen 1
chr20_+_57226284 0.101 ENST00000458280.1
ENST00000355957.5
ENST00000361770.5
ENST00000312283.8
ENST00000412911.1
ENST00000359617.4
ENST00000371141.4
STX16






syntaxin 16






chr2_+_16080659 0.100 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr22_-_42915788 0.100 ENST00000323013.6
RRP7A
ribosomal RNA processing 7 homolog A (S. cerevisiae)
chr9_-_127952032 0.099 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C


protein phosphatase 6, catalytic subunit


chr14_-_68283291 0.098 ENST00000555452.1
ENST00000347230.4
ZFYVE26

zinc finger, FYVE domain containing 26

chr7_+_91570165 0.096 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9


A kinase (PRKA) anchor protein 9


chr20_+_44746939 0.093 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr8_+_30241995 0.091 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
RBPMS



RNA binding protein with multiple splicing



chrX_-_83442915 0.090 ENST00000262752.2
ENST00000543399.1
RPS6KA6

ribosomal protein S6 kinase, 90kDa, polypeptide 6

chr17_-_38721711 0.090 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr12_+_10365404 0.089 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABARAPL1





GABA(A) receptor-associated protein like 1





chrX_+_100663243 0.089 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_-_137113604 0.088 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr17_+_7452336 0.086 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr17_+_45727204 0.081 ENST00000290158.4
KPNB1
karyopherin (importin) beta 1
chr16_-_71843047 0.079 ENST00000299980.4
ENST00000393512.3
AP1G1

adaptor-related protein complex 1, gamma 1 subunit

chr5_-_79287060 0.079 ENST00000512560.1
ENST00000509852.1
ENST00000512528.1
MTX3


metaxin 3


chr14_-_50698276 0.078 ENST00000216373.5
SOS2
son of sevenless homolog 2 (Drosophila)
chr9_+_114659046 0.076 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr1_-_159893507 0.075 ENST00000368096.1
TAGLN2
transgelin 2
chr17_+_7608511 0.073 ENST00000226091.2
EFNB3
ephrin-B3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0010757 chronological cell aging(GO:0001300) arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) negative regulation of plasminogen activation(GO:0010757) negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.6 3.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.5 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.5 1.5 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.5 0.9 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.4 1.7 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) positive regulation of vesicle fusion(GO:0031340) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.4 1.6 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.4 2.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.3 1.8 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.3 1.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.3 2.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 1.0 GO:0034959 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 0.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.4 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.2 0.6 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.6 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.2 0.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.2 0.8 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) positive regulation of dopamine receptor signaling pathway(GO:0060161) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
0.1 0.9 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.9 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.2 GO:0046520 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.1 0.6 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.1 0.4 GO:0032527 retrograde protein transport, ER to cytosol(GO:0030970) protein exit from endoplasmic reticulum(GO:0032527)
0.1 0.2 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.4 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.3 GO:0051051 negative regulation of transport(GO:0051051)
0.1 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.3 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.8 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 1.9 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.5 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 3.2 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.2 GO:0045768 obsolete positive regulation of anti-apoptosis(GO:0045768)
0.0 1.0 GO:0002208 somatic recombination of immunoglobulin genes involved in immune response(GO:0002204) somatic diversification of immunoglobulins involved in immune response(GO:0002208) isotype switching(GO:0045190)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.9 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0060744 thelarche(GO:0042695) development of secondary female sexual characteristics(GO:0046543) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.3 GO:0032288 myelin assembly(GO:0032288)
0.0 0.4 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999)
0.0 0.4 GO:1903729 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of plasma membrane organization(GO:1903729) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.7 GO:0007498 mesoderm development(GO:0007498)
0.0 0.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 1.9 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.0 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.2 1.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.3 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 1.7 GO:0042588 zymogen granule(GO:0042588)
0.1 1.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 2.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 2.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.4 1.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.3 2.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.2 0.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.5 GO:0016362 activin receptor activity, type II(GO:0016362)
0.2 1.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1 2.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.1 1.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1 2.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.8 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.3 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 2.1 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 1.5 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.