Motif ID: UGUGCUU

Z-value: 0.632


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218-5p MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_11148587 0.944 ENST00000302079.6
ENST00000580640.1
ENST00000503781.3
PIEZO2


piezo-type mechanosensitive ion channel component 2


chr20_-_4804244 0.819 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_-_154842741 0.704 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr1_-_200992827 0.669 ENST00000332129.2
ENST00000422435.2
KIF21B

kinesin family member 21B

chr4_-_40631859 0.611 ENST00000295971.7
ENST00000319592.4
RBM47

RNA binding motif protein 47

chr8_+_56014949 0.579 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_+_170590321 0.565 ENST00000392647.2
KLHL23
kelch-like family member 23
chr17_+_5185552 0.550 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr3_+_152017181 0.527 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr8_+_38614807 0.473 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr22_+_21771656 0.464 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr3_-_182698381 0.443 ENST00000292782.4
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr7_+_119913688 0.434 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr5_+_61602055 0.429 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr12_+_94542459 0.421 ENST00000258526.4
PLXNC1
plexin C1
chr10_+_22610124 0.411 ENST00000376663.3
BMI1
BMI1 polycomb ring finger oncogene
chr2_+_231729615 0.389 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
ITM2C


integral membrane protein 2C


chr15_-_61521495 0.389 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr1_+_213123915 0.383 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr3_+_69812877 0.379 ENST00000457080.1
ENST00000328528.6
MITF

microphthalmia-associated transcription factor

chr22_-_39548627 0.374 ENST00000216133.5
CBX7
chromobox homolog 7
chr7_-_55640176 0.372 ENST00000285279.5
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr5_+_112312416 0.371 ENST00000389063.2
DCP2
decapping mRNA 2
chr22_+_25960786 0.370 ENST00000324198.6
ADRBK2
adrenergic, beta, receptor kinase 2
chr8_-_8751068 0.357 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr7_+_106685079 0.351 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr3_-_53080047 0.350 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr18_+_2655692 0.349 ENST00000320876.6
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr9_-_36400213 0.343 ENST00000259605.6
ENST00000353739.4
RNF38

ring finger protein 38

chr9_-_127905736 0.343 ENST00000336505.6
ENST00000373549.4
SCAI

suppressor of cancer cell invasion

chr18_+_55102917 0.339 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr3_-_72496035 0.338 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr1_+_36348790 0.322 ENST00000373204.4
AGO1
argonaute RISC catalytic component 1
chr2_-_152955537 0.321 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr22_+_21271714 0.314 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chrX_+_108780062 0.313 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr21_+_35445827 0.310 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr2_-_69614373 0.304 ENST00000361060.5
ENST00000357308.4
GFPT1

glutamine--fructose-6-phosphate transaminase 1

chr2_-_61697862 0.299 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr17_-_46507537 0.298 ENST00000336915.6
SKAP1
src kinase associated phosphoprotein 1
chr18_-_53255766 0.295 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr15_+_91643442 0.292 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr2_-_200322723 0.291 ENST00000417098.1
SATB2
SATB homeobox 2
chr17_-_18266797 0.285 ENST00000316694.3
ENST00000539052.1
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr3_-_171178157 0.285 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr18_+_13218769 0.285 ENST00000399848.3
ENST00000361205.4
LDLRAD4

low density lipoprotein receptor class A domain containing 4

chr2_+_208394616 0.283 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr8_-_103876965 0.279 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr21_+_45285050 0.277 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr9_-_37034028 0.277 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr1_+_93544791 0.277 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2


metal response element binding transcription factor 2


chr7_-_71801980 0.274 ENST00000329008.5
CALN1
calneuron 1
chr4_+_129730779 0.272 ENST00000226319.6
PHF17
jade family PHD finger 1
chr12_-_25102252 0.271 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr2_+_79740118 0.271 ENST00000496558.1
ENST00000451966.1
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr15_+_78441663 0.269 ENST00000299518.2
ENST00000558554.1
ENST00000557826.1
ENST00000561279.1
ENST00000559186.1
ENST00000560770.1
ENST00000559881.1
ENST00000559205.1
ENST00000441490.2
IDH3A








isocitrate dehydrogenase 3 (NAD+) alpha








chr5_+_65440032 0.269 ENST00000334121.6
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr3_-_125239010 0.269 ENST00000536067.1
ENST00000251775.4
SNX4

sorting nexin 4

chr14_+_61995722 0.269 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr15_-_75249793 0.267 ENST00000322177.5
RPP25
ribonuclease P/MRP 25kDa subunit
chr6_+_12012536 0.266 ENST00000379388.2
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr5_+_127419449 0.263 ENST00000262461.2
ENST00000343225.4
SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

chr12_-_498620 0.262 ENST00000399788.2
ENST00000382815.4
KDM5A

lysine (K)-specific demethylase 5A

chr2_-_25475120 0.260 ENST00000380746.4
ENST00000402667.1
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr11_-_72853091 0.258 ENST00000311172.7
ENST00000409314.1
FCHSD2

FCH and double SH3 domains 2

chr13_+_103451399 0.257 ENST00000257336.1
ENST00000448849.2
BIVM

basic, immunoglobulin-like variable motif containing

chr4_+_140222609 0.253 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr2_+_32288725 0.253 ENST00000315285.3
SPAST
spastin
chr1_+_174769006 0.249 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_16926441 0.243 ENST00000418129.2
ENST00000396755.2
PLCL2

phospholipase C-like 2

chr12_+_69753448 0.238 ENST00000247843.2
ENST00000548020.1
ENST00000549685.1
ENST00000552955.1
YEATS4



YEATS domain containing 4



chr5_-_160973649 0.238 ENST00000393959.1
ENST00000517547.1
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr8_-_81083731 0.238 ENST00000379096.5
TPD52
tumor protein D52
chr11_+_119076745 0.238 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr12_+_120884222 0.237 ENST00000551765.1
ENST00000229384.5
GATC

glutamyl-tRNA(Gln) amidotransferase, subunit C

chr8_+_81397876 0.237 ENST00000430430.1
ZBTB10
zinc finger and BTB domain containing 10
chr13_-_79233314 0.234 ENST00000282003.6
RNF219
ring finger protein 219
chrX_+_154299753 0.233 ENST00000369459.2
ENST00000369462.1
ENST00000411985.1
ENST00000399042.1
BRCC3



BRCA1/BRCA2-containing complex, subunit 3



chr8_-_82024290 0.233 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr5_-_1524015 0.230 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr16_-_85722530 0.230 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr17_-_79885576 0.230 ENST00000574686.1
ENST00000357736.4
MAFG

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G

chr6_-_32157947 0.230 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_-_134281812 0.228 ENST00000392580.1
ENST00000312527.4
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr11_+_74303575 0.228 ENST00000263681.2
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_115910630 0.227 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr7_-_103629963 0.221 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr5_+_67511524 0.219 ENST00000521381.1
ENST00000521657.1
PIK3R1

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

chr1_+_28995231 0.217 ENST00000373816.1
GMEB1
glucocorticoid modulatory element binding protein 1
chr5_-_100238956 0.214 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr13_-_31038370 0.214 ENST00000399489.1
ENST00000339872.4
HMGB1

high mobility group box 1

chr3_+_88188254 0.214 ENST00000309495.5
ZNF654
zinc finger protein 654
chr5_+_133861790 0.211 ENST00000395003.1
PHF15
jade family PHD finger 2
chr1_+_39456895 0.211 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr5_+_126112794 0.211 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr1_+_28832455 0.209 ENST00000398958.2
ENST00000427469.1
ENST00000434290.1
ENST00000373833.6
RCC1



regulator of chromosome condensation 1



chr1_-_21978312 0.203 ENST00000359708.4
ENST00000290101.4
RAP1GAP

RAP1 GTPase activating protein

chr4_+_87856129 0.200 ENST00000395146.4
ENST00000507468.1
AFF1

AF4/FMR2 family, member 1

chr2_-_64881018 0.200 ENST00000313349.3
SERTAD2
SERTA domain containing 2
chr7_+_44788430 0.198 ENST00000457123.1
ENST00000309315.4
ZMIZ2

zinc finger, MIZ-type containing 2

chr12_-_40013553 0.197 ENST00000308666.3
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr12_+_5019061 0.196 ENST00000382545.3
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr5_+_130599735 0.195 ENST00000503291.1
ENST00000360515.3
ENST00000505065.1
CDC42SE2


CDC42 small effector 2


chr2_-_201828356 0.194 ENST00000234296.2
ORC2
origin recognition complex, subunit 2
chr4_+_160188889 0.194 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_48785216 0.193 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr20_+_35201857 0.192 ENST00000373874.2
TGIF2
TGFB-induced factor homeobox 2
chr14_-_90085458 0.192 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
FOXN3


forkhead box N3


chr3_-_135914615 0.189 ENST00000309993.2
MSL2
male-specific lethal 2 homolog (Drosophila)
chr1_-_67896095 0.189 ENST00000370994.4
SERBP1
SERPINE1 mRNA binding protein 1
chr11_-_78052923 0.186 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr17_-_76356148 0.184 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr3_+_73045936 0.181 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2




protein phosphatase 4, regulatory subunit 2




chr6_+_96463840 0.181 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr1_-_114355083 0.179 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr5_+_137688285 0.177 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr15_+_63481668 0.177 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B


RAB8B, member RAS oncogene family


chr1_+_65613217 0.177 ENST00000545314.1
AK4
adenylate kinase 4
chr5_+_96271141 0.173 ENST00000231368.5
LNPEP
leucyl/cystinyl aminopeptidase
chr1_+_212458834 0.168 ENST00000261461.2
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr4_-_39033963 0.165 ENST00000381938.3
TMEM156
transmembrane protein 156
chr6_-_97285336 0.165 ENST00000229955.3
ENST00000417980.1
GPR63

G protein-coupled receptor 63

chr11_-_118661828 0.162 ENST00000264018.4
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr6_-_24911195 0.161 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr6_+_72596604 0.160 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
RIMS1






regulating synaptic membrane exocytosis 1






chr2_+_45878790 0.159 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr6_-_16761678 0.156 ENST00000244769.4
ENST00000436367.1
ATXN1

ataxin 1

chr15_+_68346501 0.154 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr9_-_3525968 0.153 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr17_+_37026106 0.151 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr21_+_45079409 0.151 ENST00000340648.4
RRP1B
ribosomal RNA processing 1B
chrX_-_110655391 0.149 ENST00000356915.2
ENST00000356220.3
DCX

doublecortin

chr2_-_153032484 0.148 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr2_+_46769798 0.148 ENST00000238738.4
RHOQ
ras homolog family member Q
chr16_+_56225248 0.147 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr8_-_65711310 0.146 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr9_-_20622478 0.146 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr7_+_50344289 0.143 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1







IKAROS family zinc finger 1 (Ikaros)







chr14_+_100705322 0.143 ENST00000262238.4
YY1
YY1 transcription factor
chr1_+_203274639 0.142 ENST00000290551.4
BTG2
BTG family, member 2
chr11_-_75062730 0.141 ENST00000420843.2
ENST00000360025.3
ARRB1

arrestin, beta 1

chr14_-_57735528 0.139 ENST00000340918.7
ENST00000413566.2
EXOC5

exocyst complex component 5

chr3_-_24536253 0.139 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr8_+_125486939 0.138 ENST00000303545.3
RNF139
ring finger protein 139
chr17_-_79519403 0.136 ENST00000327787.8
ENST00000537152.1
C17orf70

chromosome 17 open reading frame 70

chr10_+_80828774 0.133 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr18_+_21693306 0.132 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr20_-_41818373 0.132 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT



protein tyrosine phosphatase, receptor type, T



chr10_+_76871454 0.131 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr6_-_53213780 0.131 ENST00000304434.6
ENST00000370918.4
ELOVL5

ELOVL fatty acid elongase 5

chrX_-_139866723 0.130 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chrX_+_24167746 0.130 ENST00000428571.1
ENST00000539115.1
ZFX

zinc finger protein, X-linked

chr7_+_129710350 0.129 ENST00000335420.5
ENST00000463413.1
KLHDC10

kelch domain containing 10

chr9_-_93405352 0.127 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr15_+_75287861 0.126 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
SCAMP5







secretory carrier membrane protein 5







chr4_-_23891693 0.125 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_235491462 0.123 ENST00000418304.1
ENST00000264183.3
ENST00000349213.3
ARID4B


AT rich interactive domain 4B (RBP1-like)


chr13_-_72441315 0.123 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1


dachshund homolog 1 (Drosophila)


chr8_+_50824233 0.121 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr12_-_133464151 0.121 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR




checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase




chr7_+_86273218 0.118 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr7_+_23221438 0.117 ENST00000258742.5
NUPL2
nucleoporin like 2
chr7_+_155089486 0.116 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr14_+_103058948 0.114 ENST00000262241.6
RCOR1
REST corepressor 1
chr6_+_64281906 0.114 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_-_100536608 0.113 ENST00000356828.3
ENST00000279907.7
UHRF1BP1L

UHRF1 binding protein 1-like

chr4_+_115519577 0.113 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr19_-_14316980 0.113 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr7_-_103848405 0.112 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
ORC5


origin recognition complex, subunit 5


chr19_-_33166045 0.112 ENST00000586693.3
ENST00000587352.1
ENST00000586463.1
ENST00000306065.4
ANKRD27



ankyrin repeat domain 27 (VPS9 domain)



chr15_+_57210818 0.111 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12




transcription factor 12




chr5_+_139493665 0.110 ENST00000331327.3
PURA
purine-rich element binding protein A
chr1_+_147013182 0.110 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr2_-_2334888 0.110 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr16_+_68119440 0.110 ENST00000346183.3
ENST00000329524.4
NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

chr14_+_74111578 0.110 ENST00000554113.1
ENST00000555631.2
ENST00000553645.2
ENST00000311089.3
ENST00000555919.3
ENST00000554339.1
ENST00000554871.1
DNAL1






dynein, axonemal, light chain 1






chr15_-_27018175 0.109 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr16_+_12995468 0.109 ENST00000424107.3
ENST00000558583.1
ENST00000558318.1
SHISA9


shisa family member 9


chr9_-_91793675 0.108 ENST00000375835.4
ENST00000375830.1
SHC3

SHC (Src homology 2 domain containing) transforming protein 3

chr12_+_31812602 0.103 ENST00000538463.1
ENST00000357721.3
ENST00000539633.1
METTL20


methyltransferase like 20


chr15_+_44829255 0.102 ENST00000261868.5
ENST00000424492.3
EIF3J

eukaryotic translation initiation factor 3, subunit J

chr17_+_60536002 0.102 ENST00000582809.1
TLK2
tousled-like kinase 2
chr15_+_40733387 0.101 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr12_-_54673871 0.100 ENST00000209875.4
CBX5
chromobox homolog 5
chr12_+_120875910 0.100 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr12_-_57400227 0.099 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr22_+_45559722 0.098 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50





nucleoporin 50kDa





chr19_-_38714847 0.097 ENST00000420980.2
ENST00000355526.4
DPF1

D4, zinc and double PHD fingers family 1

chr12_-_14133053 0.097 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr12_+_20522179 0.096 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr3_+_39093481 0.095 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
WDR48



WD repeat domain 48



chr1_+_214161272 0.094 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr1_+_110091189 0.094 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr10_+_119000604 0.094 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chr22_+_25202232 0.093 ENST00000400358.4
ENST00000400359.4
SGSM1

small G protein signaling modulator 1

chr11_-_10590238 0.092 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr5_-_147162078 0.092 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr4_-_185747188 0.092 ENST00000507295.1
ENST00000504900.1
ENST00000281455.2
ENST00000454703.2
ACSL1



acyl-CoA synthetase long-chain family member 1



chr11_-_45307817 0.090 ENST00000020926.3
SYT13
synaptotagmin XIII
chr1_+_63833261 0.089 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.4 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.1 0.3 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.3 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214)
0.1 0.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.3 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.5 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.2 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.4 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.1 0.2 GO:2000078 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) regulation of type B pancreatic cell development(GO:2000074) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.3 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0014889 muscle atrophy(GO:0014889)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0055005 optic placode formation involved in camera-type eye formation(GO:0046619) ventricular cardiac myofibril assembly(GO:0055005) embryonic retina morphogenesis in camera-type eye(GO:0060059) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036) negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0007202 activation of phospholipase C activity(GO:0007202) regulation of phospholipase activity(GO:0010517) positive regulation of phospholipase activity(GO:0010518) positive regulation of phospholipase C activity(GO:0010863) regulation of lipase activity(GO:0060191) positive regulation of lipase activity(GO:0060193) regulation of phospholipase C activity(GO:1900274)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:1903307 positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.3 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.0 0.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.1 GO:0016265 obsolete death(GO:0016265)
0.0 0.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.0 GO:0097576 autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.5 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.4 GO:0001508 action potential(GO:0001508)
0.0 0.7 GO:0061025 membrane fusion(GO:0061025)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0 0.0 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0044060 regulation of endocrine process(GO:0044060)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0001740 Barr body(GO:0001740)
0.1 0.2 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.5 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0042405 nuclear RNA export factor complex(GO:0042272) nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.0 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0043197 dendritic spine(GO:0043197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.1 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.1 GO:0032422 translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0030611 arsenate reductase activity(GO:0030611)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway