Motif ID: UUGGCAA
Z-value: 0.848
Mature miRNA associated with seed UUGGCAA:
Name | miRBase Accession |
---|---|
hsa-miR-182-5p | MIMAT0000259 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
0.2 | 0.8 | GO:0045112 | integrin biosynthetic process(GO:0045112) |
0.2 | 1.3 | GO:0060325 | face morphogenesis(GO:0060325) |
0.1 | 0.4 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
0.1 | 0.8 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
0.1 | 1.4 | GO:0034446 | substrate adhesion-dependent cell spreading(GO:0034446) |
0.1 | 1.3 | GO:0000052 | citrulline metabolic process(GO:0000052) arginine catabolic process(GO:0006527) |
0.1 | 0.2 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) |
0.1 | 0.3 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
0.1 | 0.2 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
0.1 | 0.2 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
0.1 | 0.4 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
0.1 | 0.1 | GO:0021873 | forebrain neuroblast division(GO:0021873) neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057) |
0.1 | 0.3 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 0.5 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.1 | 0.2 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
0.1 | 0.3 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392) |
0.1 | 0.5 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.1 | 0.1 | GO:0010761 | fibroblast migration(GO:0010761) |
0.1 | 0.4 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144) |
0.1 | 0.9 | GO:0051602 | response to electrical stimulus(GO:0051602) |
0.1 | 0.2 | GO:0008218 | bioluminescence(GO:0008218) |
0.1 | 0.7 | GO:0034405 | response to fluid shear stress(GO:0034405) |
0.0 | 0.3 | GO:0010561 | negative regulation of glycoprotein biosynthetic process(GO:0010561) |
0.0 | 0.2 | GO:0021859 | pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860) |
0.0 | 0.4 | GO:0042249 | establishment of planar polarity of embryonic epithelium(GO:0042249) |
0.0 | 0.1 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.2 | GO:0032509 | endosome transport via multivesicular body sorting pathway(GO:0032509) plasma membrane to endosome transport(GO:0048227) |
0.0 | 0.4 | GO:0048625 | myoblast fate commitment(GO:0048625) |
0.0 | 0.2 | GO:0016264 | gap junction assembly(GO:0016264) |
0.0 | 0.8 | GO:0035329 | hippo signaling(GO:0035329) |
0.0 | 1.4 | GO:0048286 | lung alveolus development(GO:0048286) |
0.0 | 0.5 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
0.0 | 0.4 | GO:0001706 | endoderm formation(GO:0001706) |
0.0 | 0.5 | GO:0001945 | lymph vessel development(GO:0001945) |
0.0 | 0.2 | GO:0097576 | vacuole fusion(GO:0097576) |
0.0 | 0.1 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.0 | 0.3 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
0.0 | 0.1 | GO:0002063 | chondrocyte development(GO:0002063) |
0.0 | 0.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.1 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243) |
0.0 | 0.2 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.0 | 0.2 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
0.0 | 0.5 | GO:0014003 | oligodendrocyte development(GO:0014003) |
0.0 | 0.0 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.0 | 0.1 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
0.0 | 0.1 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
0.0 | 0.6 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 0.3 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
0.0 | 0.2 | GO:0006707 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.0 | 0.1 | GO:0043276 | anoikis(GO:0043276) |
0.0 | 0.1 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
0.0 | 0.1 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
0.0 | 0.2 | GO:0015780 | nucleotide-sugar transport(GO:0015780) |
0.0 | 0.2 | GO:0051205 | protein insertion into membrane(GO:0051205) |
0.0 | 0.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.1 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) |
0.0 | 0.1 | GO:0016322 | neuron remodeling(GO:0016322) |
0.0 | 0.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
0.0 | 0.0 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
0.0 | 0.0 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
0.0 | 0.1 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.0 | 0.2 | GO:0031032 | actomyosin structure organization(GO:0031032) |
0.0 | 0.1 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
0.0 | 0.3 | GO:0002040 | sprouting angiogenesis(GO:0002040) |
0.0 | 0.0 | GO:0018377 | N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377) |
0.0 | 0.0 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
0.0 | 0.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.0 | 0.9 | GO:0010977 | negative regulation of neuron projection development(GO:0010977) |
0.0 | 0.0 | GO:0043558 | regulation of translational initiation in response to stress(GO:0043558) |
0.0 | 0.1 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.0 | 0.4 | GO:0044349 | nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349) |
0.0 | 0.1 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
0.0 | 0.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
0.0 | 0.0 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
0.0 | 0.3 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.1 | GO:1903729 | regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of plasma membrane organization(GO:1903729) regulation of protein localization to cell periphery(GO:1904375) |
0.0 | 0.2 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.8 | GO:0045454 | cell redox homeostasis(GO:0045454) |
0.0 | 0.1 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 0.9 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
0.2 | 1.2 | GO:0000300 | obsolete peripheral to membrane of membrane fraction(GO:0000300) |
0.1 | 0.5 | GO:0043260 | laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
0.1 | 0.6 | GO:0060171 | stereocilium membrane(GO:0060171) |
0.1 | 0.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.1 | 0.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 0.4 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
0.0 | 0.5 | GO:0001527 | microfibril(GO:0001527) |
0.0 | 0.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.0 | 0.3 | GO:0030663 | COPI-coated vesicle membrane(GO:0030663) |
0.0 | 0.6 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.3 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
0.0 | 0.2 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.0 | 0.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.1 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) beta-catenin-TCF complex(GO:1990907) |
0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.1 | GO:0035032 | phosphatidylinositol 3-kinase complex, class III(GO:0035032) PAS complex(GO:0070772) |
0.0 | 1.0 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 3.3 | GO:0005925 | focal adhesion(GO:0005925) |
0.0 | 0.8 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 0.2 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.0 | GO:0005873 | plus-end kinesin complex(GO:0005873) |
0.0 | 0.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 0.2 | GO:0031105 | septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
0.0 | 0.1 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 0.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.4 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
0.3 | 1.2 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
0.3 | 1.3 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.2 | 0.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.1 | 0.4 | GO:0070052 | collagen V binding(GO:0070052) |
0.1 | 0.4 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
0.1 | 0.7 | GO:0050693 | LBD domain binding(GO:0050693) |
0.1 | 1.9 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.1 | 0.5 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.1 | 0.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
0.1 | 0.3 | GO:0008934 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834) |
0.1 | 1.2 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.5 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 0.2 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
0.0 | 0.2 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
0.0 | 0.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.2 | GO:0042328 | heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
0.0 | 0.3 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.8 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
0.0 | 0.2 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
0.0 | 0.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0005046 | KDEL sequence binding(GO:0005046) |
0.0 | 0.3 | GO:0030172 | troponin C binding(GO:0030172) |
0.0 | 0.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325) |
0.0 | 0.3 | GO:0016004 | phospholipase activator activity(GO:0016004) |
0.0 | 0.5 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.4 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 0.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
0.0 | 0.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.7 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.2 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.0 | 0.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
0.0 | 0.4 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.0 | 0.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.2 | GO:0016595 | glutamate binding(GO:0016595) |
0.0 | 0.4 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.0 | 0.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.2 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.0 | 0.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.0 | 0.6 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
0.0 | 0.2 | GO:0016944 | obsolete RNA polymerase II transcription elongation factor activity(GO:0016944) |
0.0 | 0.0 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
0.0 | 0.2 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
0.0 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.0 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
0.0 | 0.2 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.1 | GO:0050815 | phosphoserine binding(GO:0050815) |
0.0 | 0.3 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.1 | GO:0030371 | translation repressor activity(GO:0030371) |
0.0 | 0.1 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939) |
0.0 | 0.0 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.0 | 0.2 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.0 | 0.0 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.0 | 0.0 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.0 | 0.1 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.0 | 1.5 | GO:0008194 | UDP-glycosyltransferase activity(GO:0008194) |
0.0 | 0.1 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.1 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 0.3 | GO:0030552 | cAMP binding(GO:0030552) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.1 | ST_PAC1_RECEPTOR_PATHWAY | PAC1 Receptor Pathway |