Motif ID: UUGGUCC
Z-value: 1.004
Mature miRNA associated with seed UUGGUCC:
Name | miRBase Accession |
---|---|
hsa-miR-133a-3p.2 | MIMAT0000427 |
hsa-miR-133b | MIMAT0000770 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.5 | GO:0045989 | positive regulation of striated muscle contraction(GO:0045989) |
0.3 | 0.8 | GO:0006740 | glyoxylate cycle(GO:0006097) NADPH regeneration(GO:0006740) |
0.2 | 0.7 | GO:0010837 | regulation of keratinocyte proliferation(GO:0010837) |
0.2 | 0.8 | GO:0002328 | pro-B cell differentiation(GO:0002328) |
0.1 | 0.9 | GO:0032926 | negative regulation of gonadotropin secretion(GO:0032277) negative regulation of activin receptor signaling pathway(GO:0032926) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
0.1 | 0.4 | GO:0055005 | ventricular cardiac myofibril assembly(GO:0055005) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251) |
0.1 | 1.2 | GO:0071692 | sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
0.1 | 0.5 | GO:0051409 | response to nitrosative stress(GO:0051409) |
0.1 | 0.3 | GO:0021837 | motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mesodermal cell fate specification(GO:0042661) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of mesoderm development(GO:2000380) |
0.1 | 0.3 | GO:0014029 | neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) |
0.1 | 0.2 | GO:0060267 | transformation of host cell by virus(GO:0019087) positive regulation of respiratory burst(GO:0060267) |
0.1 | 0.3 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 0.2 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
0.1 | 0.4 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
0.0 | 0.1 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.0 | 0.2 | GO:0000212 | meiotic spindle organization(GO:0000212) |
0.0 | 0.2 | GO:0007182 | common-partner SMAD protein phosphorylation(GO:0007182) |
0.0 | 0.2 | GO:0032898 | neurotrophin production(GO:0032898) |
0.0 | 0.3 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.0 | 0.6 | GO:1901224 | activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
0.0 | 0.1 | GO:0008356 | asymmetric cell division(GO:0008356) |
0.0 | 0.2 | GO:0097531 | mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531) |
0.0 | 0.1 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
0.0 | 0.2 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.0 | 0.1 | GO:0043006 | activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006) |
0.0 | 0.1 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.1 | GO:0021527 | spinal cord association neuron differentiation(GO:0021527) |
0.0 | 0.2 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
0.0 | 1.6 | GO:0042472 | inner ear morphogenesis(GO:0042472) |
0.0 | 0.3 | GO:0050872 | white fat cell differentiation(GO:0050872) |
0.0 | 0.1 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
0.0 | 0.1 | GO:0072106 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
0.0 | 0.6 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 1.0 | GO:0045576 | mast cell activation(GO:0045576) |
0.0 | 0.5 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
0.0 | 0.2 | GO:0015886 | heme transport(GO:0015886) |
0.0 | 0.2 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.4 | GO:0060056 | mammary gland involution(GO:0060056) |
0.0 | 0.1 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
0.0 | 0.6 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
0.0 | 0.1 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
0.0 | 0.8 | GO:0097479 | synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480) |
0.0 | 0.2 | GO:0010458 | exit from mitosis(GO:0010458) |
0.0 | 0.6 | GO:0051101 | regulation of DNA binding(GO:0051101) |
0.0 | 0.3 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
0.0 | 1.2 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
0.0 | 0.1 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
0.0 | 0.1 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.0 | 0.3 | GO:0006783 | heme biosynthetic process(GO:0006783) |
0.0 | 0.2 | GO:0051319 | mitotic G2 phase(GO:0000085) G2 phase(GO:0051319) |
0.0 | 0.8 | GO:0006826 | iron ion transport(GO:0006826) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.5 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
0.1 | 0.3 | GO:0033270 | paranode region of axon(GO:0033270) |
0.1 | 1.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.1 | 1.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.0 | 0.2 | GO:0005899 | insulin receptor complex(GO:0005899) |
0.0 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.0 | 0.3 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.2 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.0 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.0 | 0.4 | GO:0001527 | microfibril(GO:0001527) |
0.0 | 0.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 0.8 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 0.1 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.0 | 0.2 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
0.0 | 0.5 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.2 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.0 | 0.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
0.0 | 0.2 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 0.4 | GO:1902562 | H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
0.0 | 0.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.0 | 0.1 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
0.0 | 0.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
0.0 | 0.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 1.3 | GO:0031256 | leading edge membrane(GO:0031256) |
0.0 | 0.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
0.1 | 0.4 | GO:0050692 | DBD domain binding(GO:0050692) |
0.1 | 1.5 | GO:0001968 | fibronectin binding(GO:0001968) |
0.1 | 0.3 | GO:0032422 | translation repressor activity, nucleic acid binding(GO:0000900) purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.4 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542) |
0.1 | 0.6 | GO:0045569 | TRAIL binding(GO:0045569) |
0.1 | 0.9 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.1 | 0.2 | GO:0004797 | thymidine kinase activity(GO:0004797) |
0.1 | 0.2 | GO:0043423 | insulin-like growth factor II binding(GO:0031995) 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.0 | 0.5 | GO:0016595 | glutamate binding(GO:0016595) |
0.0 | 0.1 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
0.0 | 0.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
0.0 | 0.5 | GO:0008199 | ferric iron binding(GO:0008199) |
0.0 | 0.3 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.0 | 0.7 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
0.0 | 0.3 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.1 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
0.0 | 0.6 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.0 | 0.1 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
0.0 | 0.5 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.2 | GO:0048406 | nerve growth factor binding(GO:0048406) |
0.0 | 0.3 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
0.0 | 0.1 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
0.0 | 0.1 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.0 | 0.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.2 | GO:0015232 | heme transporter activity(GO:0015232) |
0.0 | 0.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.0 | 0.2 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 1.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.0 | 0.4 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
0.0 | 0.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.2 | GO:0017166 | vinculin binding(GO:0017166) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |