Motif ID: VAX1_GSX2
Z-value: 1.483
Transcription factors associated with VAX1_GSX2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
GSX2 | ENSG00000180613.6 | GSX2 |
VAX1 | ENSG00000148704.8 | VAX1 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.2 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
0.8 | 6.3 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.6 | 1.7 | GO:0014029 | neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034) convergent extension involved in axis elongation(GO:0060028) cellular response to prostaglandin E stimulus(GO:0071380) response to heparin(GO:0071503) cellular response to heparin(GO:0071504) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
0.4 | 2.5 | GO:0008228 | opsonization(GO:0008228) |
0.4 | 1.1 | GO:0010757 | chronological cell aging(GO:0001300) arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) negative regulation of plasminogen activation(GO:0010757) negative regulation of cell adhesion mediated by integrin(GO:0033629) |
0.4 | 2.2 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503) |
0.2 | 1.0 | GO:0001973 | adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588) |
0.2 | 1.4 | GO:0043316 | natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320) |
0.2 | 0.5 | GO:0051547 | regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549) |
0.1 | 0.6 | GO:0015811 | sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811) |
0.1 | 0.3 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.1 | 0.6 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.1 | 3.8 | GO:0090263 | positive regulation of canonical Wnt signaling pathway(GO:0090263) |
0.1 | 0.4 | GO:0009136 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188) |
0.1 | 0.1 | GO:0021873 | forebrain neuroblast division(GO:0021873) neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057) |
0.1 | 2.4 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.1 | 0.4 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.2 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
0.1 | 0.3 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
0.1 | 0.2 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
0.0 | 0.2 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.0 | 0.3 | GO:0000239 | pachytene(GO:0000239) |
0.0 | 0.7 | GO:0070206 | protein trimerization(GO:0070206) |
0.0 | 0.3 | GO:0044245 | polysaccharide digestion(GO:0044245) |
0.0 | 0.1 | GO:0009438 | methylglyoxal metabolic process(GO:0009438) |
0.0 | 0.8 | GO:0030224 | monocyte differentiation(GO:0030224) |
0.0 | 0.3 | GO:0007635 | chemosensory behavior(GO:0007635) |
0.0 | 0.4 | GO:0006907 | pinocytosis(GO:0006907) |
0.0 | 0.1 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.0 | 0.1 | GO:1902414 | protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414) |
0.0 | 0.9 | GO:0006513 | protein monoubiquitination(GO:0006513) |
0.0 | 0.1 | GO:0032472 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071) |
0.0 | 0.8 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
0.0 | 0.1 | GO:0055062 | phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506) |
0.0 | 0.6 | GO:0034199 | activation of protein kinase A activity(GO:0034199) |
0.0 | 0.5 | GO:0030574 | collagen catabolic process(GO:0030574) |
0.0 | 0.1 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) |
0.0 | 0.2 | GO:0043010 | camera-type eye development(GO:0043010) |
0.0 | 0.3 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
0.0 | 0.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
0.0 | 1.2 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
0.0 | 0.0 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
0.0 | 0.4 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.3 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.0 | 0.2 | GO:0034605 | cellular response to heat(GO:0034605) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.1 | 0.4 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 7.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.1 | 1.7 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
0.1 | 1.0 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.0 | 0.4 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) |
0.0 | 2.2 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.0 | 1.7 | GO:0031901 | early endosome membrane(GO:0031901) |
0.0 | 0.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.2 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 1.4 | GO:0030667 | secretory granule membrane(GO:0030667) |
0.0 | 0.2 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
0.0 | 0.6 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 5.3 | GO:0005792 | obsolete microsome(GO:0005792) |
0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.5 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 0.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.7 | GO:0015030 | Cajal body(GO:0015030) |
0.0 | 0.2 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.1 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.3 | 5.2 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.7 | 2.2 | GO:0050062 | long-chain-fatty-acyl-CoA reductase activity(GO:0050062) |
0.4 | 1.7 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.3 | 0.8 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
0.3 | 0.8 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
0.2 | 2.5 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
0.2 | 1.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.1 | 0.4 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.1 | 0.6 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) L-cystine transmembrane transporter activity(GO:0015184) |
0.1 | 0.2 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.1 | 1.3 | GO:0019865 | immunoglobulin binding(GO:0019865) |
0.1 | 0.2 | GO:0015254 | glycerol channel activity(GO:0015254) |
0.1 | 0.3 | GO:0004766 | spermidine synthase activity(GO:0004766) |
0.1 | 0.6 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.1 | 0.4 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.1 | 0.3 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
0.0 | 0.5 | GO:0008527 | taste receptor activity(GO:0008527) |
0.0 | 0.2 | GO:0003680 | AT DNA binding(GO:0003680) |
0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 1.2 | GO:0016251 | obsolete general RNA polymerase II transcription factor activity(GO:0016251) |
0.0 | 0.6 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 7.9 | GO:0008083 | growth factor activity(GO:0008083) |
0.0 | 0.2 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
0.0 | 0.1 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
0.0 | 1.0 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 0.4 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) snoRNA binding(GO:0030515) |
0.0 | 0.6 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.1 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
0.0 | 0.1 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.5 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 1.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.4 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |