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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_57045228	3.015	ENST00000371250.3	PPAP2B	phosphatidic acid phosphatase type 2B
chr3_+_157154578	2.816	ENST00000295927.3	PTX3	pentraxin 3, long
chr4_-_186696425	2.060	ENST00000430503.1 ENST00000319454.6 ENST00000450341.1	SORBS2	sorbin and SH3 domain containing 2
chr10_-_92681033	1.112	ENST00000371697.3	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr7_+_138145076	1.104	ENST00000343526.4	TRIM24	tripartite motif containing 24
chr4_+_88896819	1.101	ENST00000237623.7 ENST00000395080.3 ENST00000508233.1 ENST00000360804.4	SPP1	secreted phosphoprotein 1
chr12_+_26348246	1.066	ENST00000422622.2	SSPN	sarcospan
chr16_-_55866997	0.917	ENST00000360526.3 ENST00000361503.4	CES1	carboxylesterase 1
chr12_-_6233828	0.733	ENST00000572068.1 ENST00000261405.5	VWF	von Willebrand factor
chr20_+_56136136	0.707	ENST00000319441.4 ENST00000543666.1	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr15_+_58702742	0.688	ENST00000356113.6 ENST00000414170.3	LIPC	lipase, hepatic
chr19_+_50016610	0.644	ENST00000596975.1	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr12_+_81110684	0.615	ENST00000228644.3	MYF5	myogenic factor 5
chr9_+_125132803	0.587	ENST00000540753.1	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_26365443	0.569	ENST00000527422.1 ENST00000356386.2 ENST00000396934.3 ENST00000377708.2 ENST00000396948.1 ENST00000508906.2	BTN3A2	butyrophilin, subfamily 3, member A2
chr12_+_26348429	0.546	ENST00000242729.2	SSPN	sarcospan
chr16_-_28608364	0.524	ENST00000533150.1	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_85555385	0.503	ENST00000377386.3	TGOLN2	trans-golgi network protein 2
chr16_-_30122717	0.467	ENST00000566613.1	GDPD3	glycerophosphodiester phosphodiesterase domain containing 3
chr7_+_120628731	0.465	ENST00000310396.5	CPED1	cadherin-like and PC-esterase domain containing 1
chr6_-_133035185	0.456	ENST00000367928.4	VNN1	vanin 1
chr16_-_28608424	0.437	ENST00000335715.4	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr15_+_74218787	0.420	ENST00000261921.7	LOXL1	lysyl oxidase-like 1
chr7_-_100860851	0.419	ENST00000223127.3	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr14_+_74034310	0.406	ENST00000538782.1	ACOT2	acyl-CoA thioesterase 2
chr20_-_33735070	0.366	ENST00000374491.3 ENST00000542871.1 ENST00000374492.3	EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr7_-_99717463	0.365	ENST00000437822.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr16_+_72088376	0.359	ENST00000570083.1 ENST00000355906.5 ENST00000398131.2 ENST00000569639.1 ENST00000564499.1 ENST00000357763.4 ENST00000562526.1 ENST00000565574.1 ENST00000568417.2 ENST00000356967.5	HP HPR	haptoglobin haptoglobin-related protein
chr11_-_111794446	0.333	ENST00000527950.1	CRYAB	crystallin, alpha B
chr11_+_71900572	0.286	ENST00000312293.4	FOLR1	folate receptor 1 (adult)
chr11_+_71900703	0.268	ENST00000393681.2	FOLR1	folate receptor 1 (adult)
chr7_+_12727250	0.239	ENST00000404894.1	ARL4A	ADP-ribosylation factor-like 4A
chr17_+_40610862	0.239	ENST00000393829.2 ENST00000546249.1 ENST00000537728.1 ENST00000264649.6 ENST00000585525.1 ENST00000343619.4 ENST00000544137.1 ENST00000589727.1 ENST00000587824.1	ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_+_90248739	0.228	ENST00000468879.1	IGKV1D-43	immunoglobulin kappa variable 1D-43
chr6_-_82957433	0.221	ENST00000306270.7	IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr2_-_74619152	0.204	ENST00000440727.1 ENST00000409240.1	DCTN1	dynactin 1
chr19_-_46088068	0.203	ENST00000263275.4 ENST00000323060.3	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr5_+_129083772	0.200	ENST00000564719.1	KIAA1024L	KIAA1024-like
chr7_-_99716952	0.194	ENST00000523306.1 ENST00000344095.4 ENST00000417349.1 ENST00000493322.1 ENST00000520135.1 ENST00000418432.2 ENST00000460673.2 ENST00000452041.1 ENST00000452438.2 ENST00000451699.1 ENST00000453269.2	TAF6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr2_-_74618964	0.188	ENST00000417090.1 ENST00000409868.1	DCTN1	dynactin 1
chr17_+_66511540	0.173	ENST00000588188.2	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr1_-_190446759	0.170	ENST00000367462.3	BRINP3	bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr17_-_38545799	0.168	ENST00000577541.1	TOP2A	topoisomerase (DNA) II alpha 170kDa
chr12_-_10022735	0.161	ENST00000228438.2	CLEC2B	C-type lectin domain family 2, member B
chr19_+_11071546	0.151	ENST00000358026.2	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr11_-_117748138	0.146	ENST00000527717.1	FXYD6	FXYD domain containing ion transport regulator 6
chr7_+_73245193	0.142	ENST00000340958.2	CLDN4	claudin 4
chr6_+_26440700	0.135	ENST00000494393.1 ENST00000482451.1 ENST00000244519.2 ENST00000339789.4 ENST00000471353.1 ENST00000361232.3 ENST00000487627.1 ENST00000496719.1 ENST00000490254.1 ENST00000487272.1	BTN3A3	butyrophilin, subfamily 3, member A3
chr4_-_66536057	0.135	ENST00000273854.3	EPHA5	EPH receptor A5
chr4_-_74486217	0.114	ENST00000335049.5 ENST00000307439.5	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr9_-_21202204	0.114	ENST00000239347.3	IFNA7	interferon, alpha 7
chr8_-_91095099	0.108	ENST00000265431.3	CALB1	calbindin 1, 28kDa
chr9_-_95166841	0.108	ENST00000262551.4	OGN	osteoglycin
chr7_+_100860949	0.107	ENST00000305105.2	ZNHIT1	zinc finger, HIT-type containing 1
chr11_-_117747607	0.105	ENST00000540359.1 ENST00000539526.1	FXYD6	FXYD domain containing ion transport regulator 6
chr21_-_37914898	0.098	ENST00000399136.1	CLDN14	claudin 14
chr16_+_69345243	0.098	ENST00000254950.11	VPS4A	vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr17_+_48823896	0.091	ENST00000511974.1	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr12_-_10959892	0.087	ENST00000240615.2	TAS2R8	taste receptor, type 2, member 8
chr12_-_118796910	0.087	ENST00000541186.1 ENST00000539872.1	TAOK3	TAO kinase 3
chr14_+_20923350	0.086	ENST00000555414.1 ENST00000216714.3 ENST00000553681.1 ENST00000557344.1 ENST00000398030.4 ENST00000557181.1 ENST00000555839.1 ENST00000553368.1 ENST00000556054.1 ENST00000557054.1 ENST00000557592.1 ENST00000557150.1	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr3_+_152552685	0.084	ENST00000305097.3	P2RY1	purinergic receptor P2Y, G-protein coupled, 1
chr1_-_212965104	0.080	ENST00000422588.2 ENST00000366975.6 ENST00000366977.3 ENST00000366976.1	NSL1	NSL1, MIS12 kinetochore complex component
chr5_+_174151536	0.077	ENST00000239243.6 ENST00000507785.1	MSX2	msh homeobox 2
chr1_+_46972668	0.071	ENST00000371956.4 ENST00000360032.3	DMBX1	diencephalon/mesencephalon homeobox 1
chr4_-_66536196	0.068	ENST00000511294.1	EPHA5	EPH receptor A5
chr12_-_9760482	0.067	ENST00000229402.3	KLRB1	killer cell lectin-like receptor subfamily B, member 1
chr13_-_36050819	0.061	ENST00000379919.4	MAB21L1	mab-21-like 1 (C. elegans)
chr3_+_158519654	0.061	ENST00000415822.2 ENST00000392813.4 ENST00000264266.8	MFSD1	major facilitator superfamily domain containing 1
chr2_-_89340242	0.057	ENST00000480492.1	IGKV1-12	immunoglobulin kappa variable 1-12
chr5_-_149829294	0.056	ENST00000401695.3	RPS14	ribosomal protein S14
chr5_-_149829244	0.055	ENST00000312037.5	RPS14	ribosomal protein S14
chr12_-_22063787	0.054	ENST00000544039.1	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_35258592	0.051	ENST00000342280.4 ENST00000450137.1	GJA4	gap junction protein, alpha 4, 37kDa
chr15_+_80351910	0.051	ENST00000261749.6 ENST00000561060.1	ZFAND6	zinc finger, AN1-type domain 6
chr15_-_37393406	0.050	ENST00000338564.5 ENST00000558313.1 ENST00000340545.5	MEIS2	Meis homeobox 2
chr4_-_74486347	0.050	ENST00000342081.3	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr17_+_48823975	0.048	ENST00000513969.1 ENST00000503728.1	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr7_-_44122063	0.047	ENST00000335195.6 ENST00000395831.3 ENST00000414235.1 ENST00000452049.1 ENST00000242248.5	POLM	polymerase (DNA directed), mu
chr9_-_21239978	0.040	ENST00000380222.2	IFNA14	interferon, alpha 14
chr14_-_53258314	0.038	ENST00000216410.3 ENST00000557604.1	GNPNAT1	glucosamine-phosphate N-acetyltransferase 1
chrX_+_7137475	0.035	ENST00000217961.4	STS	steroid sulfatase (microsomal), isozyme S
chr5_-_149829314	0.034	ENST00000407193.1	RPS14	ribosomal protein S14
chr6_+_26402465	0.032	ENST00000476549.2 ENST00000289361.6 ENST00000450085.2 ENST00000425234.2 ENST00000427334.1 ENST00000506698.1	BTN3A1	butyrophilin, subfamily 3, member A1
chr3_+_186353756	0.031	ENST00000431018.1 ENST00000450521.1 ENST00000539949.1	FETUB	fetuin B
chr9_-_95166884	0.028	ENST00000375561.5	OGN	osteoglycin
chr15_+_80351977	0.025	ENST00000559157.1 ENST00000561012.1 ENST00000564367.1 ENST00000558494.1	ZFAND6	zinc finger, AN1-type domain 6
chr10_+_18549645	0.022	ENST00000396576.2	CACNB2	calcium channel, voltage-dependent, beta 2 subunit
chr17_-_10372875	0.017	ENST00000255381.2	MYH4	myosin, heavy chain 4, skeletal muscle
chr5_-_20575959	0.014	ENST00000507958.1	CDH18	cadherin 18, type 2
chr3_+_115342349	0.014	ENST00000393780.3	GAP43	growth associated protein 43
chr19_+_12175504	0.013	ENST00000439326.3	ZNF844	zinc finger protein 844
chr4_+_80584903	0.013	ENST00000506460.1	RP11-452C8.1	RP11-452C8.1
chr14_+_72399833	0.011	ENST00000553530.1 ENST00000556437.1	RGS6	regulator of G-protein signaling 6
chr17_-_18430160	0.008	ENST00000392176.3	FAM106A	family with sequence similarity 106, member A
chr11_-_117747434	0.004	ENST00000529335.2 ENST00000530956.1 ENST00000260282.4	FXYD6	FXYD domain containing ion transport regulator 6
chr14_+_32798547	0.002	ENST00000557354.1 ENST00000557102.1 ENST00000557272.1	AKAP6	A kinase (PRKA) anchor protein 6

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.8	GO:0008228	opsonization(GO:0008228)
0.4	1.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.3	3.0	GO:0008354	germ cell migration(GO:0008354)
0.1	0.3	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.4	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1	0.6	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.7	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	1.1	GO:0046697	decidualization(GO:0046697)
0.1	1.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.1	0.5	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	1.0	GO:0009309	amine biosynthetic process(GO:0009309)
0.0	0.2	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.6	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.7	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0072207	metanephric tubule development(GO:0072170) metanephric epithelium development(GO:0072207) metanephric nephron tubule development(GO:0072234) metanephric nephron epithelium development(GO:0072243)
0.0	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.4	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.7	GO:0033093	Weibel-Palade body(GO:0033093)
0.1	0.4	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	1.6	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	3.2	GO:0031674	I band(GO:0031674)
0.0	0.1	GO:0036452	ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.0	0.6	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.7	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	1.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	0.7	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.2	2.8	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	0.9	GO:0080030	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.2	0.6	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	1.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	1.1	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.5	GO:0017159	pantetheine hydrolase activity(GO:0017159) GPI anchor binding(GO:0034235)
0.1	0.3	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1	0.5	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.7	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	2.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.6	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.7	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.4	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.6	GO:0005542	folic acid binding(GO:0005542)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.6	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	ST_MYOCYTE_AD_PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.9	SA_PROGRAMMED_CELL_DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

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