Motif ID: VDR
Z-value: 0.782
Transcription factors associated with VDR:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
VDR | ENSG00000111424.6 | VDR |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
0.1 | 0.4 | GO:0052805 | histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805) |
0.1 | 0.9 | GO:0014049 | positive regulation of glutamate secretion(GO:0014049) |
0.1 | 0.7 | GO:0042420 | dopamine catabolic process(GO:0042420) |
0.1 | 0.8 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
0.1 | 0.8 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.1 | 0.3 | GO:0034442 | plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
0.1 | 0.4 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
0.1 | 0.3 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
0.1 | 0.2 | GO:0002124 | territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625) |
0.1 | 0.3 | GO:0000394 | RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.1 | 0.2 | GO:0043371 | negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515) |
0.1 | 0.2 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
0.1 | 0.5 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
0.1 | 0.8 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.1 | 0.3 | GO:0045916 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
0.0 | 0.7 | GO:0032456 | endocytic recycling(GO:0032456) |
0.0 | 0.8 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
0.0 | 0.2 | GO:0015868 | purine ribonucleotide transport(GO:0015868) |
0.0 | 0.1 | GO:0007028 | cytoplasm organization(GO:0007028) ribonucleoprotein complex disassembly(GO:0032988) |
0.0 | 0.4 | GO:0097435 | myelin assembly(GO:0032288) extracellular fibril organization(GO:0043206) fibril organization(GO:0097435) |
0.0 | 0.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
0.0 | 0.6 | GO:1901224 | activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224) |
0.0 | 0.2 | GO:0019471 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511) |
0.0 | 1.5 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
0.0 | 0.3 | GO:0010799 | regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
0.0 | 0.6 | GO:0051923 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923) |
0.0 | 0.2 | GO:0070254 | mucus secretion(GO:0070254) |
0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
0.0 | 0.2 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
0.0 | 0.1 | GO:0021938 | smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) |
0.0 | 0.1 | GO:0007351 | tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) |
0.0 | 0.1 | GO:0071364 | cellular response to epidermal growth factor stimulus(GO:0071364) |
0.0 | 0.0 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
0.0 | 0.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.1 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
0.0 | 0.1 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
0.0 | 0.2 | GO:0006491 | N-glycan processing(GO:0006491) |
0.0 | 0.1 | GO:0007210 | serotonin receptor signaling pathway(GO:0007210) |
0.0 | 0.1 | GO:0007141 | male meiosis I(GO:0007141) |
0.0 | 0.0 | GO:0001575 | globoside metabolic process(GO:0001575) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.3 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.3 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.0 | 0.8 | GO:0042627 | chylomicron(GO:0042627) |
0.0 | 1.2 | GO:0043195 | terminal bouton(GO:0043195) |
0.0 | 1.2 | GO:0045095 | keratin filament(GO:0045095) |
0.0 | 0.3 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 1.0 | GO:0030175 | filopodium(GO:0030175) |
0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
0.0 | 0.1 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
0.0 | 1.1 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 0.1 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 0.8 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.2 | 0.8 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 0.7 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.1 | 0.7 | GO:0032190 | acrosin binding(GO:0032190) |
0.1 | 0.4 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
0.1 | 0.7 | GO:0045569 | TRAIL binding(GO:0045569) |
0.1 | 0.8 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
0.1 | 0.3 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.1 | 0.9 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
0.1 | 0.2 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
0.1 | 0.4 | GO:0034711 | inhibin binding(GO:0034711) |
0.1 | 0.3 | GO:0004064 | arylesterase activity(GO:0004064) |
0.1 | 0.7 | GO:0030547 | receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019) |
0.1 | 0.6 | GO:0001848 | complement binding(GO:0001848) |
0.0 | 0.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
0.0 | 0.2 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.0 | 0.2 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
0.0 | 0.2 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 0.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
0.0 | 0.3 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 0.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.3 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 2.3 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
0.0 | 0.1 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
0.0 | 0.7 | GO:0004385 | guanylate kinase activity(GO:0004385) |
0.0 | 0.1 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
0.0 | 0.2 | GO:0043274 | phospholipase binding(GO:0043274) |
0.0 | 0.1 | GO:0019841 | retinol binding(GO:0019841) |
0.0 | 0.1 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
0.0 | 0.0 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
0.0 | 0.1 | GO:0008148 | obsolete negative transcription elongation factor activity(GO:0008148) |
0.0 | 0.3 | GO:0070330 | aromatase activity(GO:0070330) |
0.0 | 0.1 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
0.0 | 0.6 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.0 | 1.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
0.0 | 0.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.7 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 0.4 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |