Motif ID: VDR

Z-value: 0.782


Transcription factors associated with VDR:

Gene SymbolEntrez IDGene Name
VDR ENSG00000111424.6 VDR



Activity profile for motif VDR.

activity profile for motif VDR


Sorted Z-values histogram for motif VDR

Sorted Z-values for motif VDR



Network of associatons between targets according to the STRING database.



First level regulatory network of VDR

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_52626898 1.126 ENST00000331817.5
KRT7
keratin 7
chr2_-_235405168 0.934 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr8_+_26371763 0.874 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr17_-_7082861 0.842 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr2_+_11752379 0.835 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr17_+_2699697 0.833 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2


RAP1 GTPase activating protein 2


chr8_+_95653427 0.818 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653302 0.794 ENST00000423620.2
ENST00000433389.2
ESRP1

epithelial splicing regulatory protein 1

chr17_-_64225508 0.782 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr8_+_95653373 0.776 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr4_+_85504075 0.751 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr14_+_95047744 0.744 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
SERPINA5



serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5



chrX_+_43515467 0.728 ENST00000338702.3
ENST00000542639.1
MAOA

monoamine oxidase A

chr11_-_104817919 0.719 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr10_+_54074033 0.706 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr9_+_71789133 0.663 ENST00000348208.4
ENST00000265384.7
TJP2

tight junction protein 2

chr6_+_31916733 0.601 ENST00000483004.1
CFB
complement factor B
chr7_+_94536898 0.528 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr19_+_41281416 0.510 ENST00000597140.1
MIA
melanoma inhibitory activity
chr11_-_119991589 0.481 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr19_+_41281282 0.465 ENST00000263369.3
MIA
melanoma inhibitory activity
chr8_-_22926623 0.435 ENST00000276431.4
TNFRSF10B
tumor necrosis factor receptor superfamily, member 10b
chr19_+_41281060 0.432 ENST00000594436.1
ENST00000597784.1
MIA

melanoma inhibitory activity

chr12_-_133050726 0.405 ENST00000595994.1
MUC8
mucin 8
chrX_-_130423200 0.393 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr11_-_104840093 0.386 ENST00000417440.2
ENST00000444739.2
CASP4

caspase 4, apoptosis-related cysteine peptidase

chr14_-_35873856 0.381 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha


chr10_-_13523073 0.365 ENST00000440282.1
BEND7
BEN domain containing 7
chr2_+_108905325 0.346 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2


sulfotransferase family, cytosolic, 1C, member 2


chr7_-_95025661 0.323 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr3_+_54157480 0.316 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr11_+_57365150 0.301 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr20_+_3801162 0.289 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1



adaptor-related protein complex 5, sigma 1 subunit



chrX_-_13835147 0.276 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr19_+_54694119 0.268 ENST00000456872.1
ENST00000302937.4
ENST00000429671.2
TSEN34


TSEN34 tRNA splicing endonuclease subunit


chr10_-_33623826 0.264 ENST00000374867.2
NRP1
neuropilin 1
chr2_-_203736334 0.258 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
ICA1L


islet cell autoantigen 1,69kDa-like


chr7_+_29234101 0.257 ENST00000435288.2
CHN2
chimerin 2
chr2_+_210517895 0.253 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr2_+_54342574 0.246 ENST00000303536.4
ENST00000394666.3
ACYP2

acylphosphatase 2, muscle type

chr8_-_145028013 0.242 ENST00000354958.2
PLEC
plectin
chr19_+_1407517 0.241 ENST00000336761.6
ENST00000233078.4
DAZAP1

DAZ associated protein 1

chr8_+_17434689 0.241 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr6_+_167704838 0.239 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr17_-_36347835 0.238 ENST00000519532.1
TBC1D3
TBC1 domain family, member 3
chr21_-_47575481 0.238 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr16_+_19078960 0.237 ENST00000568985.1
ENST00000566110.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chr2_+_108905095 0.236 ENST00000251481.6
ENST00000326853.5
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chrX_-_13835461 0.233 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr17_-_34756219 0.231 ENST00000451448.2
ENST00000394359.3
TBC1D3C
TBC1D3H
TBC1 domain family, member 3C
TBC1 domain family, member 3H
chr6_+_30852130 0.229 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1



discoidin domain receptor tyrosine kinase 1



chr6_+_167704798 0.228 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr8_-_22926526 0.221 ENST00000347739.3
ENST00000542226.1
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr8_-_13134045 0.218 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr16_+_19079311 0.215 ENST00000569127.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr17_+_36284791 0.213 ENST00000505415.1
TBC1D3F
TBC1 domain family, member 3F
chr17_-_36348610 0.213 ENST00000339023.4
ENST00000354664.4
TBC1D3

TBC1 domain family, member 3

chrY_+_16636354 0.213 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr4_-_39640700 0.210 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr17_-_34807272 0.209 ENST00000535592.1
ENST00000394453.1
TBC1D3G

TBC1 domain family, member 3G

chr7_+_29234028 0.202 ENST00000222792.6
CHN2
chimerin 2
chr2_+_46926326 0.199 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr16_+_19078911 0.198 ENST00000321998.5
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr1_+_54519242 0.187 ENST00000234827.1
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr14_-_54908043 0.174 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1




cornichon family AMPA receptor auxiliary protein 1




chr17_-_34808047 0.173 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1D3G




TBC1D3H
TBC1 domain family, member 3G




TBC1 domain family, member 3H
chr16_+_14802801 0.172 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr1_+_3816936 0.171 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
RP13-15E13.1


long intergenic non-protein coding RNA 1134


chr20_-_52790512 0.171 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chrX_+_70435044 0.171 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1


gap junction protein, beta 1, 32kDa


chr5_-_179227540 0.167 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr10_-_33623564 0.165 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr3_+_57541975 0.161 ENST00000487257.1
ENST00000311180.8
PDE12

phosphodiesterase 12

chr11_-_65667997 0.160 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr16_+_19079215 0.158 ENST00000544894.2
ENST00000561858.1
COQ7

coenzyme Q7 homolog, ubiquinone (yeast)

chr16_-_28937027 0.158 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr7_-_16844611 0.157 ENST00000401412.1
ENST00000419304.2
AGR2

anterior gradient 2

chr2_+_113342163 0.157 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr17_-_34591208 0.156 ENST00000336331.5
TBC1D3C
TBC1 domain family, member 3C
chr17_-_79805146 0.156 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr7_+_100318423 0.156 ENST00000252723.2
EPO
erythropoietin
chr14_-_20801427 0.152 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr12_-_96390063 0.149 ENST00000541929.1
HAL
histidine ammonia-lyase
chr6_+_125475335 0.148 ENST00000532429.1
ENST00000534199.1
TPD52L1

tumor protein D52-like 1

chr5_-_147211226 0.144 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr5_-_147211190 0.141 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr11_+_6624970 0.140 ENST00000420936.2
ENST00000528995.1
ILK

integrin-linked kinase

chr1_+_92414952 0.139 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT








bromodomain, testis-specific








chr19_+_56652686 0.137 ENST00000592949.1
ZNF444
zinc finger protein 444
chr7_-_151433342 0.134 ENST00000433631.2
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_16045665 0.133 ENST00000248041.8
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr19_-_5903714 0.131 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chrX_+_149737046 0.128 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
MTM1




myotubularin 1




chr7_-_151433393 0.127 ENST00000492843.1
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_47987419 0.126 ENST00000536339.1
ENST00000595554.1
ENST00000600271.1
ENST00000338134.3
KPTN



kaptin (actin binding protein)



chr11_-_65667884 0.126 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr11_-_73882029 0.126 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr20_+_55904815 0.124 ENST00000371263.3
ENST00000345868.4
ENST00000371260.4
ENST00000418127.1
SPO11



SPO11 meiotic protein covalently bound to DSB



chr1_+_100111580 0.124 ENST00000605497.1
PALMD
palmdelphin
chr19_-_16045619 0.122 ENST00000402119.4
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr3_+_184032919 0.119 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr7_-_105029812 0.119 ENST00000482897.1
SRPK2
SRSF protein kinase 2
chr11_+_6624955 0.117 ENST00000299421.4
ENST00000537806.1
ILK

integrin-linked kinase

chr10_-_32345305 0.117 ENST00000302418.4
KIF5B
kinesin family member 5B
chr8_+_119294456 0.115 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr11_+_6625046 0.115 ENST00000396751.2
ILK
integrin-linked kinase
chr3_+_46618727 0.114 ENST00000296145.5
TDGF1
teratocarcinoma-derived growth factor 1
chr13_+_24844819 0.112 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr12_-_63328817 0.103 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_38826415 0.100 ENST00000410018.1
ENST00000409235.3
CATSPERG

catsper channel auxiliary subunit gamma

chr9_+_139839711 0.098 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr1_+_200993071 0.094 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1

RP11-168O16.1

chr6_-_30524951 0.094 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr22_-_29663954 0.092 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr6_-_8064567 0.091 ENST00000543936.1
ENST00000397457.2
BLOC1S5

biogenesis of lysosomal organelles complex-1, subunit 5, muted

chr1_-_110613276 0.090 ENST00000369792.4
ALX3
ALX homeobox 3
chr3_+_132036207 0.089 ENST00000336375.5
ENST00000495911.1
ACPP

acid phosphatase, prostate

chr3_-_122283100 0.086 ENST00000492382.1
ENST00000462315.1
PARP9

poly (ADP-ribose) polymerase family, member 9

chr12_+_52695617 0.085 ENST00000293525.5
KRT86
keratin 86
chr11_+_28129795 0.084 ENST00000406787.3
ENST00000342303.5
ENST00000403099.1
ENST00000407364.3
METTL15



methyltransferase like 15



chr19_-_54693401 0.080 ENST00000338624.6
MBOAT7
membrane bound O-acyltransferase domain containing 7
chr2_-_232329186 0.079 ENST00000322723.4
NCL
nucleolin
chr1_-_67519782 0.078 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr15_-_81282133 0.077 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr4_-_11430221 0.076 ENST00000514690.1
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr3_+_190105909 0.074 ENST00000456423.1
CLDN16
claudin 16
chr11_+_64808675 0.074 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr3_-_178969403 0.072 ENST00000314235.5
ENST00000392685.2
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_+_113779704 0.071 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr8_+_12809093 0.070 ENST00000528753.2
KIAA1456
KIAA1456
chr12_+_57857475 0.069 ENST00000528467.1
GLI1
GLI family zinc finger 1
chr8_+_9046503 0.068 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr16_-_28936493 0.068 ENST00000544477.1
ENST00000357573.6
RABEP2

rabaptin, RAB GTPase binding effector protein 2

chr16_+_69958887 0.066 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr5_+_177433973 0.066 ENST00000507848.1
FAM153C
family with sequence similarity 153, member C
chr2_-_170681324 0.066 ENST00000409340.1
METTL5
methyltransferase like 5
chr11_-_506316 0.066 ENST00000532055.1
ENST00000531540.1
RNH1

ribonuclease/angiogenin inhibitor 1

chr10_-_33624002 0.065 ENST00000432372.2
NRP1
neuropilin 1
chr20_+_39765581 0.064 ENST00000244007.3
PLCG1
phospholipase C, gamma 1
chr22_+_29664305 0.063 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWSR1



EWS RNA-binding protein 1



chr2_+_102928009 0.062 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr11_+_94706804 0.061 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr4_-_36246060 0.061 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_+_45071622 0.060 ENST00000428034.1
CLEC3B
C-type lectin domain family 3, member B
chr3_+_13521665 0.057 ENST00000295757.3
ENST00000402259.1
ENST00000402271.1
ENST00000446613.2
ENST00000404548.1
ENST00000404040.1
HDAC11





histone deacetylase 11





chr12_+_79439405 0.057 ENST00000552744.1
SYT1
synaptotagmin I
chr5_+_175487692 0.056 ENST00000510151.1
FAM153B
family with sequence similarity 153, member B
chr12_-_96390108 0.055 ENST00000538703.1
ENST00000261208.3
HAL

histidine ammonia-lyase

chr19_+_16830774 0.055 ENST00000524140.2
NWD1
NACHT and WD repeat domain containing 1
chr9_-_139343294 0.054 ENST00000313084.5
SEC16A
SEC16 homolog A (S. cerevisiae)
chr19_-_44860820 0.053 ENST00000354340.4
ENST00000337401.4
ENST00000587909.1
ZNF112


zinc finger protein 112


chr17_+_43224684 0.053 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr4_-_165898768 0.052 ENST00000329314.5
TRIM61
tripartite motif containing 61
chr4_-_77997126 0.051 ENST00000537948.1
ENST00000507788.1
ENST00000237654.4
CCNI


cyclin I


chr9_+_139839686 0.051 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr15_-_42565606 0.051 ENST00000307216.6
ENST00000448392.1
TMEM87A

transmembrane protein 87A

chr1_+_28099683 0.049 ENST00000373943.4
STX12
syntaxin 12
chr19_+_7599597 0.048 ENST00000414982.3
ENST00000450331.3
PNPLA6

patatin-like phospholipase domain containing 6

chr5_-_177210399 0.048 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr2_-_85625857 0.048 ENST00000453973.1
CAPG
capping protein (actin filament), gelsolin-like
chr16_+_16043406 0.047 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1





ATP-binding cassette, sub-family C (CFTR/MRP), member 1





chr19_-_54804173 0.046 ENST00000391744.3
ENST00000251390.3
LILRA3

leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

chr2_-_73511559 0.045 ENST00000521871.1
FBXO41
F-box protein 41
chr20_+_2276639 0.045 ENST00000381458.5
TGM3
transglutaminase 3
chr6_+_79577189 0.044 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr11_+_18433840 0.043 ENST00000541669.1
ENST00000280704.4
LDHC

lactate dehydrogenase C

chr19_+_14017116 0.043 ENST00000589606.1
CC2D1A
coiled-coil and C2 domain containing 1A
chr8_+_98900132 0.043 ENST00000520016.1
MATN2
matrilin 2
chr16_+_28834303 0.042 ENST00000340394.8
ENST00000325215.6
ENST00000395547.2
ENST00000336783.4
ENST00000382686.4
ENST00000564304.1
ATXN2L





ataxin 2-like





chr16_-_28506840 0.042 ENST00000569430.1
CLN3
ceroid-lipofuscinosis, neuronal 3
chr4_-_122854612 0.042 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr16_+_67207838 0.041 ENST00000566871.1
ENST00000268605.7
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr12_-_6579833 0.040 ENST00000396308.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr12_+_110011571 0.039 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr1_+_26348259 0.039 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr5_+_175488258 0.035 ENST00000512862.1
FAM153B
family with sequence similarity 153, member B
chr19_+_39936186 0.035 ENST00000432763.2
ENST00000402194.2
ENST00000601515.1
SUPT5H


suppressor of Ty 5 homolog (S. cerevisiae)


chr15_+_41952591 0.033 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA



MGA, MAX dimerization protein



chr7_-_36764142 0.032 ENST00000258749.5
ENST00000535891.1
AOAH

acyloxyacyl hydrolase (neutrophil)

chr1_+_27561104 0.032 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr16_+_640201 0.032 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr12_-_114404111 0.032 ENST00000545145.2
ENST00000392561.3
ENST00000261741.5
RBM19


RNA binding motif protein 19


chr16_+_67207872 0.031 ENST00000563258.1
ENST00000568146.1
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr9_+_111624577 0.030 ENST00000333999.3
ACTL7A
actin-like 7A
chr10_+_119301928 0.030 ENST00000553456.3
EMX2
empty spiracles homeobox 2
chr15_+_69307028 0.028 ENST00000388866.3
ENST00000530406.2
NOX5

NADPH oxidase, EF-hand calcium binding domain 5

chr19_-_13261160 0.028 ENST00000343587.5
ENST00000591197.1
STX10

syntaxin 10

chr1_-_19426149 0.028 ENST00000429347.2
UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr5_-_177209832 0.028 ENST00000393518.3
ENST00000505531.1
ENST00000503567.1
FAM153A


family with sequence similarity 153, member A


chr3_-_3151664 0.027 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA



interleukin 5 receptor, alpha



chr11_+_124609823 0.027 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr22_+_29664248 0.026 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWSR1



EWS RNA-binding protein 1



chr11_+_63998198 0.025 ENST00000321460.5
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr8_-_93115445 0.025 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_93781728 0.024 ENST00000314622.4
NSUN3
NOP2/Sun domain family, member 3
chr12_-_6579808 0.024 ENST00000535180.1
ENST00000400911.3
VAMP1

vesicle-associated membrane protein 1 (synaptobrevin 1)

chr6_-_32145101 0.024 ENST00000375104.2
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_+_94640633 0.024 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr14_+_22963806 0.023 ENST00000390493.1
TRAJ44
T cell receptor alpha joining 44
chr6_+_24775153 0.023 ENST00000356509.3
ENST00000230056.3
GMNN

geminin, DNA replication inhibitor


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.4 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.9 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.2 GO:0002124 territorial aggressive behavior(GO:0002124) brainstem development(GO:0003360) vocalization behavior(GO:0071625)
0.1 0.3 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623) negative regulation of CD4-positive, alpha-beta T cell activation(GO:2000515)
0.1 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.3 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028) ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0097435 myelin assembly(GO:0032288) extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.6 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 1.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.6 GO:0051923 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) sulfation(GO:0051923)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0001575 globoside metabolic process(GO:0001575)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.7 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.7 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.8 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.7 GO:0030547 receptor inhibitor activity(GO:0030547) receptor antagonist activity(GO:0048019)
0.1 0.6 GO:0001848 complement binding(GO:0001848)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0008148 obsolete negative transcription elongation factor activity(GO:0008148)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.6 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.