Motif ID: VENTX

Z-value: 1.437


Transcription factors associated with VENTX:

Gene SymbolEntrez IDGene Name
VENTX ENSG00000151650.7 VENTX



Activity profile for motif VENTX.

activity profile for motif VENTX


Sorted Z-values histogram for motif VENTX

Sorted Z-values for motif VENTX



Network of associatons between targets according to the STRING database.



First level regulatory network of VENTX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_84035905 3.809 ENST00000311507.4
PLAC8
placenta-specific 8
chr4_-_84035868 3.740 ENST00000426923.2
ENST00000509973.1
PLAC8

placenta-specific 8

chr4_-_155511887 2.068 ENST00000302053.3
ENST00000403106.3
FGA

fibrinogen alpha chain

chr17_+_47448102 2.064 ENST00000576461.1
RP11-81K2.1
Uncharacterized protein
chr6_-_39693111 1.410 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6



kinesin family member 6



chr12_+_25205568 1.336 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr7_-_22234381 1.336 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_+_25205446 1.296 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr18_+_55888767 1.250 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr9_+_2159850 1.211 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_-_130423200 1.207 ENST00000361420.3
IGSF1
immunoglobulin superfamily, member 1
chr1_+_226411319 1.195 ENST00000542034.1
ENST00000366810.5
MIXL1

Mix paired-like homeobox

chr18_+_29171689 1.178 ENST00000237014.3
TTR
transthyretin
chr12_+_25205666 1.144 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr6_+_114178512 1.045 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_23886285 1.004 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_+_7618413 0.927 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr8_+_50824233 0.911 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chrX_-_130423240 0.911 ENST00000370910.1
ENST00000370901.4
IGSF1

immunoglobulin superfamily, member 1

chr16_-_67517716 0.868 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr12_+_56473939 0.856 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_+_75526212 0.796 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr4_-_105416039 0.772 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr9_+_116225999 0.728 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr8_+_107738240 0.708 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr6_+_12290586 0.652 ENST00000379375.5
EDN1
endothelin 1
chr14_-_20801427 0.644 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
CCNB1IP1


cyclin B1 interacting protein 1, E3 ubiquitin protein ligase


chr18_-_74207146 0.639 ENST00000443185.2
ZNF516
zinc finger protein 516
chrX_+_133733457 0.627 ENST00000440614.1
RP11-308B5.2
RP11-308B5.2
chr11_-_107729887 0.614 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr18_+_59000815 0.546 ENST00000262717.4
CDH20
cadherin 20, type 2
chr1_+_168250194 0.542 ENST00000367821.3
TBX19
T-box 19
chr16_-_51185172 0.521 ENST00000251020.4
SALL1
spalt-like transcription factor 1
chr12_+_56473910 0.502 ENST00000411731.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr2_+_171034646 0.485 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr12_-_6233828 0.484 ENST00000572068.1
ENST00000261405.5
VWF

von Willebrand factor

chr6_+_153552455 0.479 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr3_+_134514093 0.478 ENST00000398015.3
EPHB1
EPH receptor B1
chr8_-_103425047 0.423 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr12_+_81110684 0.417 ENST00000228644.3
MYF5
myogenic factor 5
chr12_-_16758059 0.417 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr13_-_28545276 0.408 ENST00000381020.7
CDX2
caudal type homeobox 2
chr4_-_26492076 0.401 ENST00000295589.3
CCKAR
cholecystokinin A receptor
chr8_-_103424986 0.399 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr18_-_53253323 0.396 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr8_-_103424916 0.393 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr2_+_226265364 0.385 ENST00000272907.6
NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr2_-_203776864 0.377 ENST00000261015.4
WDR12
WD repeat domain 12
chr6_-_76203345 0.372 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr20_-_50722183 0.320 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr1_+_153747746 0.314 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr2_-_88285309 0.304 ENST00000420840.2
RGPD2
RANBP2-like and GRIP domain containing 2
chr18_-_53253112 0.291 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4


transcription factor 4


chr3_-_57233966 0.285 ENST00000473921.1
ENST00000295934.3
HESX1

HESX homeobox 1

chr17_-_47045949 0.275 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chrX_+_135730297 0.268 ENST00000370629.2
CD40LG
CD40 ligand
chr22_-_40929812 0.259 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr17_-_202579 0.259 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chr1_+_62417957 0.257 ENST00000307297.7
ENST00000543708.1
INADL

InaD-like (Drosophila)

chr4_-_168155169 0.251 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr12_-_101604185 0.242 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr1_+_62439037 0.240 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_-_32157947 0.240 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr11_+_22359562 0.237 ENST00000263160.3
SLC17A6
solute carrier family 17 (vesicular glutamate transporter), member 6
chrX_+_105937068 0.227 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr13_-_67802549 0.222 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr20_+_42136308 0.214 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1



l(3)mbt-like 1 (Drosophila)



chr17_+_68100989 0.213 ENST00000585558.1
ENST00000392670.1
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr2_+_166152283 0.213 ENST00000375427.2
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr9_+_133539981 0.208 ENST00000253008.2
PRDM12
PR domain containing 12
chr2_-_163008903 0.201 ENST00000418842.2
ENST00000375497.3
GCG

glucagon

chr11_+_46722368 0.194 ENST00000311764.2
ZNF408
zinc finger protein 408
chr17_-_48785216 0.182 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr12_+_52695617 0.182 ENST00000293525.5
KRT86
keratin 86
chr5_-_82969405 0.180 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr6_+_167704798 0.172 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr12_-_53994805 0.166 ENST00000328463.7
ATF7
activating transcription factor 7
chr12_-_102591604 0.163 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chrX_+_135730373 0.161 ENST00000370628.2
CD40LG
CD40 ligand
chr1_+_150337100 0.157 ENST00000401000.4
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr9_+_117904097 0.155 ENST00000374016.1
DEC1
deleted in esophageal cancer 1
chr9_+_136501478 0.150 ENST00000393056.2
ENST00000263611.2
DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chr3_+_171561127 0.148 ENST00000334567.5
ENST00000450693.1
TMEM212

transmembrane protein 212

chr1_+_150337144 0.144 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
RPRD2


regulation of nuclear pre-mRNA domain containing 2


chr5_-_79950775 0.144 ENST00000439211.2
DHFR
dihydrofolate reductase
chr11_-_11374904 0.137 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr1_+_186265399 0.136 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr2_+_87135076 0.135 ENST00000409776.2
RGPD1
RANBP2-like and GRIP domain containing 1
chr6_+_167704838 0.133 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr2_-_165698662 0.130 ENST00000194871.6
ENST00000445474.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chr6_-_99873145 0.129 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr8_+_26150628 0.129 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr5_-_130500922 0.119 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
HINT1



histidine triad nucleotide binding protein 1



chr6_-_111927062 0.115 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr1_-_28527152 0.108 ENST00000321830.5
AL353354.1
Uncharacterized protein
chr5_+_43121698 0.106 ENST00000505606.2
ENST00000509634.1
ENST00000509341.1
ZNF131


zinc finger protein 131


chr14_+_65453432 0.104 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr12_-_51611477 0.101 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr5_-_156486120 0.101 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr6_+_152011628 0.100 ENST00000404742.1
ENST00000440973.1
ESR1

estrogen receptor 1

chr17_-_10372875 0.091 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr14_+_32798462 0.091 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr17_-_39222131 0.086 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr3_+_9834227 0.076 ENST00000287613.7
ENST00000397261.3
ARPC4

actin related protein 2/3 complex, subunit 4, 20kDa

chr8_-_87755878 0.075 ENST00000320005.5
CNGB3
cyclic nucleotide gated channel beta 3
chr7_+_139025875 0.071 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr1_-_190446759 0.064 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr22_+_39101728 0.062 ENST00000216044.5
ENST00000484657.1
GTPBP1

GTP binding protein 1

chr19_-_15529790 0.054 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
AKAP8L




A kinase (PRKA) anchor protein 8-like




chr7_-_104909435 0.054 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr11_-_3859089 0.050 ENST00000396979.1
RHOG
ras homolog family member G
chrX_+_78003204 0.041 ENST00000435339.3
ENST00000514744.1
LPAR4

lysophosphatidic acid receptor 4

chr2_-_165698521 0.040 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1


cordon-bleu WH2 repeat protein-like 1


chr2_+_45168875 0.038 ENST00000260653.3
SIX3
SIX homeobox 3
chr11_+_64018955 0.034 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3


phospholipase C, beta 3 (phosphatidylinositol-specific)


chr6_-_90529418 0.030 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1


MDN1, midasin homolog (yeast)


chr4_+_37455536 0.012 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060024 rhythmic synaptic transmission(GO:0060024) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 3.8 GO:0006906 vesicle fusion(GO:0006906)
0.2 1.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.2 0.9 GO:0060259 regulation of feeding behavior(GO:0060259)
0.2 1.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.1 1.2 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 0.4 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.1 0.5 GO:0060677 ureteric bud elongation(GO:0060677) renal vesicle formation(GO:0072033)
0.1 0.8 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.5 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 1.0 GO:0030903 notochord development(GO:0030903)
0.1 0.4 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.3 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.4 GO:0043586 tongue development(GO:0043586)
0.1 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.2 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.2 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 2.1 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.5 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0060235 forebrain anterior/posterior pattern specification(GO:0021797) lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0 1.0 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.4 GO:0007018 microtubule-based movement(GO:0007018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 1.0 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 1.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0034711 inhibin binding(GO:0034711)
0.2 0.9 GO:0008907 integrase activity(GO:0008907)
0.2 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 1.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.4 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.7 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 1.2 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 2.1 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.1 0.2 GO:0031493 nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.1 GO:0004146 dihydrofolate reductase activity(GO:0004146)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 1.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)