Motif ID: VSX1
Z-value: 0.746
Transcription factors associated with VSX1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| VSX1 | ENSG00000100987.10 | VSX1 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.6 | GO:0000059 | protein import into nucleus, docking(GO:0000059) |
| 0.1 | 0.7 | GO:0002903 | negative regulation of B cell apoptotic process(GO:0002903) |
| 0.1 | 0.4 | GO:0061032 | visceral serous pericardium development(GO:0061032) |
| 0.1 | 0.5 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
| 0.1 | 0.4 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.1 | 0.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 0.4 | GO:0006789 | bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980) |
| 0.1 | 0.4 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 0.6 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) |
| 0.1 | 0.3 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) |
| 0.1 | 0.2 | GO:0031034 | skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688) |
| 0.1 | 0.5 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.1 | 0.2 | GO:0071418 | uroporphyrinogen III biosynthetic process(GO:0006780) cellular response to amine stimulus(GO:0071418) |
| 0.1 | 0.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.4 | GO:0042693 | muscle cell fate commitment(GO:0042693) |
| 0.1 | 0.2 | GO:0006434 | seryl-tRNA aminoacylation(GO:0006434) |
| 0.0 | 0.7 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.2 | GO:1902745 | positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745) |
| 0.0 | 0.3 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.1 | GO:0046520 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520) |
| 0.0 | 0.1 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.0 | 0.1 | GO:1904358 | positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358) |
| 0.0 | 0.1 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
| 0.0 | 0.1 | GO:0006435 | threonyl-tRNA aminoacylation(GO:0006435) |
| 0.0 | 0.1 | GO:0032465 | regulation of cytokinesis(GO:0032465) |
| 0.0 | 0.1 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.0 | 0.5 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 2.2 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 0.3 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.1 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.0 | 0.2 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.2 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 0.1 | GO:0030812 | muscle hypertrophy in response to stress(GO:0003299) response to stimulus involved in regulation of muscle adaptation(GO:0014874) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898) negative regulation of nucleotide catabolic process(GO:0030812) |
| 0.0 | 0.1 | GO:2000172 | regulation of branching morphogenesis of a nerve(GO:2000172) |
| 0.0 | 0.1 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.6 | GO:0006693 | prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.4 | GO:0008299 | isoprenoid biosynthetic process(GO:0008299) |
| 0.0 | 0.6 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.4 | GO:0060393 | regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393) |
| 0.0 | 0.1 | GO:0006553 | lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554) |
| 0.0 | 0.3 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.0 | 0.1 | GO:0048755 | branching morphogenesis of a nerve(GO:0048755) |
| 0.0 | 0.2 | GO:0006386 | transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386) |
| 0.0 | 0.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 0.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.5 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 0.3 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.2 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
| 0.0 | 0.1 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 0.1 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.1 | 0.5 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.1 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.8 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.0 | 0.2 | GO:0038201 | TORC2 complex(GO:0031932) TOR complex(GO:0038201) |
| 0.0 | 2.1 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.1 | GO:0036452 | ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452) |
| 0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.1 | GO:0005687 | U4 snRNP(GO:0005687) U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
| 0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.1 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.5 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.0 | 0.2 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.2 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.8 | GO:0005761 | organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761) |
| 0.0 | 0.2 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 0.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.1 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.0 | 0.4 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 0.1 | GO:0000109 | nucleotide-excision repair complex(GO:0000109) |
| 0.0 | 0.1 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 0.1 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.0 | 0.2 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.0 | GO:0042584 | chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:0034597 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
| 0.2 | 0.5 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
| 0.1 | 0.6 | GO:0047026 | androsterone dehydrogenase (A-specific) activity(GO:0047026) |
| 0.1 | 0.3 | GO:0047718 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115) indanol dehydrogenase activity(GO:0047718) |
| 0.1 | 0.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 0.4 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
| 0.1 | 0.3 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.1 | 0.3 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.1 | 0.2 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.1 | 0.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 0.6 | GO:0015288 | porin activity(GO:0015288) |
| 0.1 | 0.2 | GO:0004738 | pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739) |
| 0.1 | 0.2 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.1 | 0.2 | GO:0004828 | serine-tRNA ligase activity(GO:0004828) |
| 0.0 | 0.6 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.0 | 0.2 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.0 | 0.6 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.1 | GO:0004829 | threonine-tRNA ligase activity(GO:0004829) |
| 0.0 | 0.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.3 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.0 | 0.1 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.6 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.0 | 0.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.1 | GO:0031994 | insulin-like growth factor I binding(GO:0031994) |
| 0.0 | 0.4 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.0 | 0.1 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.2 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.4 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.7 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.1 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.0 | 0.1 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.0 | 0.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.1 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
| 0.0 | 0.2 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 0.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.0 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.8 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.4 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
