Motif ID: YY1_YY2

Z-value: 1.744

Transcription factors associated with YY1_YY2:

Gene SymbolEntrez IDGene Name
YY1 ENSG00000100811.6 YY1
YY2 ENSG00000230797.2 YY2






Network of associatons between targets according to the STRING database.



First level regulatory network of YY1_YY2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_149688896 4.527 ENST00000239940.7
PFN2
profilin 2
chr3_-_149688502 4.499 ENST00000481767.1
ENST00000475518.1
PFN2

profilin 2

chr3_-_149688655 4.236 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2




profilin 2




chr2_-_190044480 3.040 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr12_-_91539918 2.353 ENST00000548218.1
DCN
decorin
chr5_-_16936340 2.281 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr2_-_175870085 2.253 ENST00000409156.3
CHN1
chimerin 1
chr17_-_3571934 2.246 ENST00000225525.3
TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr15_+_63340647 2.122 ENST00000404484.4
TPM1
tropomyosin 1 (alpha)
chrX_-_153236819 2.089 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr15_+_33022885 2.086 ENST00000322805.4
GREM1
gremlin 1, DAN family BMP antagonist
chr2_-_175869936 2.044 ENST00000409900.3
CHN1
chimerin 1
chr14_-_53417732 2.035 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2



fermitin family member 2



chr14_-_53331239 1.947 ENST00000553663.1
FERMT2
fermitin family member 2
chr3_-_123304017 1.818 ENST00000383657.5
PTPLB
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b
chr9_-_35689900 1.769 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
TPM2


tropomyosin 2 (beta)


chr15_+_63340858 1.739 ENST00000560615.1
TPM1
tropomyosin 1 (alpha)
chr7_+_134551583 1.713 ENST00000435928.1
CALD1
caldesmon 1
chr15_+_63340734 1.669 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr15_+_63340553 1.637 ENST00000334895.5
TPM1
tropomyosin 1 (alpha)
chr4_-_52904425 1.601 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr2_+_242255297 1.569 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2









septin 2









chr16_-_74640986 1.566 ENST00000422840.2
ENST00000565260.1
ENST00000447066.2
ENST00000205061.5
GLG1



golgi glycoprotein 1



chr15_+_63334831 1.530 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
TPM1








tropomyosin 1 (alpha)








chr15_+_63340775 1.504 ENST00000559281.1
ENST00000317516.7
TPM1

tropomyosin 1 (alpha)

chr22_-_36236623 1.495 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_175712270 1.495 ENST00000295497.7
ENST00000444394.1
CHN1

chimerin 1

chr9_-_131709858 1.492 ENST00000372586.3
DOLK
dolichol kinase
chrX_+_102631844 1.483 ENST00000372634.1
ENST00000299872.7
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr5_+_71403061 1.471 ENST00000512974.1
ENST00000296755.7
MAP1B

microtubule-associated protein 1B

chr12_+_13349650 1.464 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr2_-_216257849 1.461 ENST00000456923.1
FN1
fibronectin 1
chr20_+_56884752 1.419 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr1_-_151965048 1.411 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr6_+_31588478 1.395 ENST00000376007.4
ENST00000376033.2
PRRC2A

proline-rich coiled-coil 2A

chr6_+_151561506 1.386 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr1_+_114522049 1.371 ENST00000369551.1
ENST00000320334.4
OLFML3

olfactomedin-like 3

chrX_-_153237258 1.348 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr17_-_1303462 1.327 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
YWHAE



tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon



chr14_-_30396802 1.313 ENST00000415220.2
PRKD1
protein kinase D1
chr22_-_36236265 1.310 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr22_+_39916558 1.250 ENST00000337304.2
ENST00000396680.1
ATF4

activating transcription factor 4

chr11_+_69455855 1.249 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr11_+_129939779 1.225 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2




amyloid beta (A4) precursor-like protein 2




chr6_-_43484718 1.211 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr6_+_121756809 1.204 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr11_+_129939811 1.160 ENST00000345598.5
ENST00000338167.5
APLP2

amyloid beta (A4) precursor-like protein 2

chr18_-_812517 1.159 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr20_-_17641097 1.155 ENST00000246043.4
RRBP1
ribosome binding protein 1
chr6_-_74363803 1.154 ENST00000355773.5
SLC17A5
solute carrier family 17 (acidic sugar transporter), member 5
chr16_-_66785497 1.147 ENST00000440564.2
ENST00000379482.2
ENST00000443351.2
ENST00000566150.1
DYNC1LI2



dynein, cytoplasmic 1, light intermediate chain 2



chr3_-_185542761 1.147 ENST00000457616.2
ENST00000346192.3
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_-_153599426 1.142 ENST00000392622.1
S100A13
S100 calcium binding protein A13
chr3_-_185542817 1.116 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_242254679 1.112 ENST00000428282.1
ENST00000360051.3
SEPT2

septin 2

chr10_-_70092671 1.111 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
PBLD


phenazine biosynthesis-like protein domain containing


chr6_+_33168637 1.111 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr11_-_47270341 1.105 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
ACP2







acid phosphatase 2, lysosomal







chr6_+_33168597 1.103 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr12_-_91546926 1.081 ENST00000550758.1
DCN
decorin
chr14_-_23504087 1.078 ENST00000493471.2
ENST00000460922.2
PSMB5

proteasome (prosome, macropain) subunit, beta type, 5

chr6_-_138428613 1.076 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr12_+_58087901 1.070 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9









osteosarcoma amplified 9, endoplasmic reticulum lectin









chr9_+_131873659 1.067 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4





protein phosphatase 2A activator, regulatory subunit 4





chr6_-_43484621 1.041 ENST00000506469.1
ENST00000503972.1
YIPF3

Yip1 domain family, member 3

chr10_+_17271266 1.034 ENST00000224237.5
VIM
vimentin
chr8_+_30300119 1.028 ENST00000520191.1
RBPMS
RNA binding protein with multiple splicing
chr17_-_46682321 1.025 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chrX_-_153236620 1.000 ENST00000369984.4
HCFC1
host cell factor C1 (VP16-accessory protein)
chr4_+_76439665 0.996 ENST00000508105.1
ENST00000311638.3
ENST00000380837.3
ENST00000507556.1
ENST00000504190.1
ENST00000507885.1
ENST00000502620.1
ENST00000514480.1
THAP6







THAP domain containing 6







chrX_+_102840408 0.984 ENST00000468024.1
ENST00000472484.1
ENST00000415568.2
ENST00000490644.1
ENST00000459722.1
ENST00000472745.1
ENST00000494801.1
ENST00000434216.2
ENST00000425011.1
TCEAL4








transcription elongation factor A (SII)-like 4








chr3_-_99833333 0.982 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L


filamin A interacting protein 1-like


chr17_+_38599693 0.976 ENST00000542955.1
ENST00000269593.4
IGFBP4

insulin-like growth factor binding protein 4

chr12_-_110434183 0.957 ENST00000360185.4
ENST00000354574.4
ENST00000338373.5
ENST00000343646.5
ENST00000356259.4
ENST00000553118.1
GIT2





G protein-coupled receptor kinase interacting ArfGAP 2





chr16_-_2827128 0.957 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
TCEB2




transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)




chr6_+_146864829 0.947 ENST00000367495.3
RAB32
RAB32, member RAS oncogene family
chr2_+_242255275 0.941 ENST00000391971.2
SEPT2
septin 2
chr6_+_151561085 0.939 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_6309963 0.937 ENST00000382515.2
CD9
CD9 molecule
chr14_-_23504337 0.937 ENST00000361611.6
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr11_+_77532233 0.922 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chrX_+_67718863 0.913 ENST00000374622.2
YIPF6
Yip1 domain family, member 6
chr2_+_187454749 0.912 ENST00000261023.3
ENST00000374907.3
ITGAV

integrin, alpha V

chr1_-_144932014 0.912 ENST00000529945.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr8_+_136469684 0.908 ENST00000355849.5
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr16_+_83841448 0.905 ENST00000433866.2
HSBP1
heat shock factor binding protein 1
chr11_-_117166276 0.895 ENST00000510630.1
ENST00000392937.6
BACE1

beta-site APP-cleaving enzyme 1

chr11_+_842928 0.889 ENST00000397408.1
TSPAN4
tetraspanin 4
chr14_-_30396948 0.888 ENST00000331968.5
PRKD1
protein kinase D1
chr9_+_131873591 0.870 ENST00000393370.2
ENST00000337738.1
ENST00000348141.5
PPP2R4


protein phosphatase 2A activator, regulatory subunit 4


chr7_-_41740181 0.869 ENST00000442711.1
INHBA
inhibin, beta A
chrX_+_153237740 0.868 ENST00000369982.4
TMEM187
transmembrane protein 187
chr5_-_148930960 0.866 ENST00000261798.5
ENST00000377843.2
CSNK1A1

casein kinase 1, alpha 1

chr1_+_81771806 0.866 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2





latrophilin 2





chr11_-_65640325 0.862 ENST00000307998.6
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr6_-_32145861 0.856 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr14_-_23504432 0.855 ENST00000425762.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr2_-_242254595 0.850 ENST00000441124.1
ENST00000391976.2
HDLBP

high density lipoprotein binding protein

chr2_+_102508955 0.845 ENST00000414004.2
FLJ20373
FLJ20373
chr11_-_65640198 0.841 ENST00000528176.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr7_-_6523755 0.839 ENST00000258739.4
ENST00000436575.1
KDELR2
DAGLB
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase, beta
chrX_-_10645773 0.832 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_9413410 0.825 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS


tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase


chr11_-_111782696 0.822 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr2_-_242255117 0.821 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
HDLBP


high density lipoprotein binding protein


chr12_+_56211703 0.806 ENST00000243045.5
ENST00000552672.1
ENST00000550836.1
ORMDL2


ORM1-like 2 (S. cerevisiae)


chr20_+_30193083 0.806 ENST00000376112.3
ENST00000376105.3
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr12_-_110434021 0.781 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
GIT2


G protein-coupled receptor kinase interacting ArfGAP 2


chr14_+_69865401 0.776 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9


solute carrier family 39, member 9


chr4_+_47487285 0.770 ENST00000273859.3
ENST00000504445.1
ATP10D

ATPase, class V, type 10D

chr19_-_5622991 0.768 ENST00000252542.4
SAFB2
scaffold attachment factor B2
chr16_+_69221028 0.763 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_-_27205136 0.759 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr7_-_72972319 0.758 ENST00000223368.2
BCL7B
B-cell CLL/lymphoma 7B
chr2_+_66662690 0.753 ENST00000488550.1
MEIS1
Meis homeobox 1
chr2_+_202899310 0.749 ENST00000286201.1
FZD7
frizzled family receptor 7
chr1_-_43232649 0.749 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
LEPRE1



leucine proline-enriched proteoglycan (leprecan) 1



chr16_-_88923285 0.747 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
GALNS



galactosamine (N-acetyl)-6-sulfate sulfatase



chr13_-_45150392 0.744 ENST00000501704.2
TSC22D1
TSC22 domain family, member 1
chr9_+_470288 0.739 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr15_+_63335899 0.730 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr2_+_33172012 0.730 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr14_+_62162258 0.728 ENST00000337138.4
ENST00000394997.1
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr8_+_26371763 0.727 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chr14_-_51411146 0.727 ENST00000532462.1
PYGL
phosphorylase, glycogen, liver
chr19_+_17326191 0.725 ENST00000595101.1
ENST00000596136.1
ENST00000379776.4
USE1


unconventional SNARE in the ER 1 homolog (S. cerevisiae)


chr16_-_1020954 0.723 ENST00000543238.1
ENST00000539379.1
ENST00000399843.2
ENST00000262301.11
LMF1



lipase maturation factor 1



chr11_+_114310237 0.717 ENST00000539119.1
REXO2
RNA exonuclease 2
chr9_-_99381660 0.715 ENST00000375240.3
ENST00000463569.1
CDC14B

cell division cycle 14B

chr11_+_114310102 0.714 ENST00000265881.5
REXO2
RNA exonuclease 2
chr15_+_90808919 0.709 ENST00000379095.3
NGRN
neugrin, neurite outgrowth associated
chr1_-_1167346 0.706 ENST00000545427.1
ENST00000360001.6
SDF4

stromal cell derived factor 4

chr19_-_42463418 0.704 ENST00000600292.1
ENST00000601078.1
ENST00000601891.1
ENST00000222008.6
RABAC1



Rab acceptor 1 (prenylated)



chr19_+_17326141 0.700 ENST00000445667.2
ENST00000263897.5
USE1

unconventional SNARE in the ER 1 homolog (S. cerevisiae)

chr1_-_226374373 0.697 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr3_+_10068095 0.697 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr8_-_67525473 0.697 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr19_+_11546093 0.695 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr14_+_50234827 0.695 ENST00000554589.1
ENST00000557247.1
KLHDC2

kelch domain containing 2

chr2_+_66662510 0.688 ENST00000272369.9
ENST00000407092.2
MEIS1

Meis homeobox 1

chr17_+_42634844 0.686 ENST00000315323.3
FZD2
frizzled family receptor 2
chr8_+_26435359 0.684 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr14_-_51411194 0.683 ENST00000544180.2
PYGL
phosphorylase, glycogen, liver
chr3_+_159557637 0.676 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr11_+_114310164 0.673 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2


RNA exonuclease 2


chr11_+_77532155 0.671 ENST00000532481.1
ENST00000526415.1
ENST00000393427.2
ENST00000527134.1
ENST00000304716.8
AAMDC




adipogenesis associated, Mth938 domain containing




chr11_+_842808 0.669 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chr12_-_53574376 0.666 ENST00000267085.4
ENST00000379850.3
ENST00000379846.1
ENST00000424990.1
CSAD



cysteine sulfinic acid decarboxylase



chr1_+_164528866 0.663 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr1_-_227506158 0.648 ENST00000366769.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr2_+_33172221 0.644 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_156105878 0.642 ENST00000508500.1
LMNA
lamin A/C
chr1_+_100111479 0.640 ENST00000263174.4
PALMD
palmdelphin
chr18_-_812231 0.639 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr18_-_34408902 0.634 ENST00000593035.1
ENST00000383056.3
ENST00000588909.1
ENST00000590337.1
TPGS2



tubulin polyglutamylase complex subunit 2



chr3_+_52489503 0.634 ENST00000345716.4
NISCH
nischarin
chr20_-_60942361 0.630 ENST00000252999.3
LAMA5
laminin, alpha 5
chr3_-_114035026 0.630 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr2_+_173292280 0.624 ENST00000264107.7
ITGA6
integrin, alpha 6
chr20_+_53092123 0.623 ENST00000262593.5
DOK5
docking protein 5
chr19_+_11546153 0.620 ENST00000591946.1
ENST00000252455.2
ENST00000412601.1
PRKCSH


protein kinase C substrate 80K-H


chr7_+_6414128 0.614 ENST00000348035.4
ENST00000356142.4
RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

chr12_+_8234807 0.612 ENST00000339754.5
NECAP1
NECAP endocytosis associated 1
chr3_-_136471204 0.610 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1



stromal antigen 1



chr16_+_2564254 0.606 ENST00000565223.1
ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr2_-_201729284 0.606 ENST00000434813.2
CLK1
CDC-like kinase 1
chr15_-_71146480 0.605 ENST00000299213.8
LARP6
La ribonucleoprotein domain family, member 6
chr10_-_81205373 0.604 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr14_-_74551172 0.604 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_+_36023035 0.603 ENST00000373253.3
NCDN
neurochondrin
chr1_+_223900034 0.603 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr12_-_53574418 0.597 ENST00000379843.3
ENST00000453446.2
ENST00000437073.1
CSAD


cysteine sulfinic acid decarboxylase


chr10_+_104503727 0.593 ENST00000448841.1
WBP1L
WW domain binding protein 1-like
chr16_+_8736232 0.592 ENST00000562973.1
METTL22
methyltransferase like 22
chr10_-_92681033 0.591 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr19_+_39214797 0.590 ENST00000440400.1
ACTN4
actinin, alpha 4
chr14_+_75746781 0.589 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr4_+_77870960 0.588 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11


septin 11


chr3_-_114343768 0.587 ENST00000393785.2
ZBTB20
zinc finger and BTB domain containing 20
chr17_+_37844331 0.587 ENST00000578199.1
ENST00000406381.2
ERBB2

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2

chr11_-_111782484 0.584 ENST00000533971.1
CRYAB
crystallin, alpha B
chr2_+_210517895 0.580 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr17_-_1359443 0.577 ENST00000574295.1
ENST00000398970.5
ENST00000300574.2
CRK


v-crk avian sarcoma virus CT10 oncogene homolog


chr19_+_3094398 0.576 ENST00000078429.4
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr5_-_54603368 0.576 ENST00000508346.1
ENST00000251636.5
DHX29

DEAH (Asp-Glu-Ala-His) box polypeptide 29

chr1_-_227505826 0.575 ENST00000334218.5
ENST00000366766.2
ENST00000366764.2
CDC42BPA


CDC42 binding protein kinase alpha (DMPK-like)


chr20_+_44563267 0.575 ENST00000372409.3
PCIF1
PDX1 C-terminal inhibiting factor 1
chr3_+_142442841 0.567 ENST00000476941.1
ENST00000273482.6
TRPC1

transient receptor potential cation channel, subfamily C, member 1

chr2_+_173292390 0.567 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr11_+_65686802 0.566 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr10_+_104613980 0.559 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr2_-_201729393 0.557 ENST00000321356.4
CLK1
CDC-like kinase 1
chr6_-_33239612 0.555 ENST00000482399.1
ENST00000445902.2
VPS52

vacuolar protein sorting 52 homolog (S. cerevisiae)

chr1_+_36023370 0.553 ENST00000356090.4
ENST00000373243.2
NCDN

neurochondrin

chr17_-_46671323 0.552 ENST00000239151.5
HOXB5
homeobox B5
chr1_-_103574024 0.550 ENST00000512756.1
ENST00000370096.3
ENST00000358392.2
ENST00000353414.4
COL11A1



collagen, type XI, alpha 1



chr1_-_9884011 0.550 ENST00000361311.4
CLSTN1
calsyntenin 1
chr2_+_113403434 0.547 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr5_-_176981417 0.544 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B


family with sequence similarity 193, member B


chr22_+_31489344 0.543 ENST00000404574.1
SMTN
smoothelin

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.9 GO:0003065 regulation of heart rate by chemical signal(GO:0003062) positive regulation of heart rate by epinephrine(GO:0003065)
1.1 4.4 GO:0019046 release from viral latency(GO:0019046)
0.6 3.9 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.6 2.2 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.5 2.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.5 1.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.5 0.9 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.5 1.4 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.4 1.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.4 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 0.3 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.3 0.9 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.3 1.2 GO:0033197 response to vitamin E(GO:0033197)
0.3 3.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 0.3 GO:0051170 nuclear import(GO:0051170)
0.3 1.2 GO:0051503 purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503)
0.3 2.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.3 1.3 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.3 0.8 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.2 0.7 GO:0009996 negative regulation of cell fate specification(GO:0009996) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2 0.7 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.2 1.4 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 2.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.2 1.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.2 0.9 GO:0030913 paranodal junction assembly(GO:0030913)
0.2 0.7 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.2 0.9 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.2 0.7 GO:0035330 regulation of hippo signaling(GO:0035330)
0.2 2.2 GO:0001967 suckling behavior(GO:0001967)
0.2 0.6 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.6 GO:0018377 N-terminal protein myristoylation(GO:0006499) protein myristoylation(GO:0018377)
0.2 0.6 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 2.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.2 0.2 GO:0001816 cytokine production(GO:0001816)
0.2 0.6 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.2 0.5 GO:0007028 cytoplasm organization(GO:0007028) ribonucleoprotein complex disassembly(GO:0032988)
0.2 0.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 2.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 0.5 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.2 0.5 GO:0035120 post-embryonic appendage morphogenesis(GO:0035120)
0.2 0.2 GO:0009101 glycoprotein biosynthetic process(GO:0009101)
0.2 0.3 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.2 1.1 GO:0030007 cellular potassium ion homeostasis(GO:0030007) negative regulation of cell volume(GO:0045794)
0.2 0.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.2 0.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 1.4 GO:0071692 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.3 GO:0031133 regulation of axon diameter(GO:0031133) regulation of cell projection size(GO:0032536)
0.2 0.2 GO:0043113 receptor clustering(GO:0043113)
0.1 2.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.6 GO:0060209 estrus(GO:0060209)
0.1 14.0 GO:0008064 regulation of actin polymerization or depolymerization(GO:0008064)
0.1 0.4 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1 0.4 GO:0003011 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.1 3.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.7 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.1 0.5 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.6 GO:0090343 positive regulation of cell aging(GO:0090343)
0.1 0.8 GO:0046541 saliva secretion(GO:0046541)
0.1 1.2 GO:0009650 UV protection(GO:0009650)
0.1 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.1 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.5 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 0.1 GO:0021543 pallium development(GO:0021543)
0.1 3.0 GO:0006829 zinc II ion transport(GO:0006829)
0.1 0.6 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 2.0 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.4 GO:0001824 blastocyst development(GO:0001824)
0.1 0.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 1.0 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.3 GO:0042759 fatty acid elongation, saturated fatty acid(GO:0019367) long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) establishment of epithelial cell apical/basal polarity(GO:0045198) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.3 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 1.0 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 2.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 1.4 GO:0007032 endosome organization(GO:0007032)
0.1 3.4 GO:0007041 lysosomal transport(GO:0007041)
0.1 0.1 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.3 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.9 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 0.3 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting two-sector ATPase complex assembly(GO:0070071) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.1 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1 0.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.2 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.1 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.1 0.3 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.1 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.1 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.3 GO:0016236 macroautophagy(GO:0016236)
0.1 0.2 GO:0048821 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.1 0.6 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.2 GO:0060206 estrous cycle phase(GO:0060206)
0.1 0.7 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 4.7 GO:0008360 regulation of cell shape(GO:0008360)
0.1 2.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.8 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 1.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.1 GO:0007403 glial cell fate determination(GO:0007403)
0.1 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 1.2 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 1.3 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.4 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 1.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.9 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 3.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0 0.3 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.2 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009) foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047) iris morphogenesis(GO:0061072) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.0 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.2 GO:0050668 positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of cellular amine metabolic process(GO:0033239) positive regulation of cellular amino acid metabolic process(GO:0045764) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:0036315 cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.0 0.2 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.3 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.0 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.2 GO:0015827 tryptophan transport(GO:0015827) leucine import(GO:0060356)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 1.5 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0000087 mitotic M phase(GO:0000087)
0.0 1.1 GO:0072595 maintenance of protein location in nucleus(GO:0051457) maintenance of protein localization in organelle(GO:0072595)
0.0 0.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 3.5 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.5 GO:0046697 decidualization(GO:0046697)
0.0 0.9 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.4 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 1.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) negative regulation of protein depolymerization(GO:1901880)
0.0 0.2 GO:0010993 ubiquitin homeostasis(GO:0010992) regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.0 0.2 GO:0045727 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.2 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) regulation of mitotic sister chromatid separation(GO:0010965) regulation of mitotic sister chromatid segregation(GO:0033047) metaphase/anaphase transition of cell cycle(GO:0044784) chromosome separation(GO:0051304) mitotic sister chromatid separation(GO:0051306)
0.0 0.0 GO:0045908 negative regulation of vasodilation(GO:0045908)
0.0 2.2 GO:0006665 sphingolipid metabolic process(GO:0006665)
0.0 0.4 GO:0048488 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.7 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.4 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 2.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0043583 ear development(GO:0043583)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0034337 RNA folding(GO:0034337) DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) regulation of DNA methylation(GO:0044030)
0.0 0.5 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.2 GO:0007584 response to nutrient(GO:0007584)
0.0 0.3 GO:0060393 pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 0.6 GO:0045446 endothelial cell differentiation(GO:0045446)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0098930 axonal transport(GO:0098930)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0046952 cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952)
0.0 0.7 GO:0010332 response to gamma radiation(GO:0010332)
0.0 1.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 2.2 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.1 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.0 0.6 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.9 GO:0050817 blood coagulation(GO:0007596) hemostasis(GO:0007599) coagulation(GO:0050817)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.8 GO:1901264 carbohydrate derivative transport(GO:1901264)
0.0 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.7 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.6 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0050704 regulation of interleukin-1 secretion(GO:0050704) positive regulation of interleukin-1 secretion(GO:0050716)
0.0 3.8 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.4 GO:0007033 vacuole organization(GO:0007033)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0050790 regulation of catalytic activity(GO:0050790)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.4 GO:0031929 TOR signaling(GO:0031929)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0001895 retina homeostasis(GO:0001895) photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.0 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0007626 locomotory behavior(GO:0007626)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0007616 long-term memory(GO:0007616) synaptic vesicle docking(GO:0016081)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.4 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.4 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.1 GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway(GO:0031635) opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.0 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.2 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.0 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.1 GO:0000097 sulfur amino acid biosynthetic process(GO:0000097) methionine biosynthetic process(GO:0009086)
0.0 0.0 GO:0060969 negative regulation of gene silencing(GO:0060969)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.4 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.9 GO:2000116 regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043281) regulation of cysteine-type endopeptidase activity(GO:2000116)
0.0 0.4 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 12.3 GO:0032059 bleb(GO:0032059)
1.0 3.0 GO:0005588 collagen type V trimer(GO:0005588)
0.5 4.1 GO:0000145 exocyst(GO:0000145)
0.3 3.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 0.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.2 3.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 0.2 GO:0019717 obsolete synaptosome(GO:0019717)
0.2 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2 0.6 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 0.6 GO:0043260 laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0043219 lateral loop(GO:0043219)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.1 GO:0070820 tertiary granule(GO:0070820)
0.1 1.3 GO:0034464 BBSome(GO:0034464)
0.1 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 6.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.4 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0033655 host(GO:0018995) host cell cytoplasm(GO:0030430) host cell part(GO:0033643) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.1 GO:0043202 lysosomal lumen(GO:0043202)
0.1 2.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.5 GO:0005915 zonula adherens(GO:0005915)
0.1 0.3 GO:0070695 FHF complex(GO:0070695)
0.1 1.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.1 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.6 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 2.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.9 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 2.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.9 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.1 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.8 GO:0015630 microtubule cytoskeleton(GO:0015630)
0.1 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 1.9 GO:0043195 terminal bouton(GO:0043195)
0.1 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.1 3.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 0.7 GO:0055037 recycling endosome(GO:0055037)
0.1 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.9 GO:0030914 STAGA complex(GO:0030914)
0.0 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.5 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.0 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 17.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.6 GO:0030175 filopodium(GO:0030175)
0.0 2.9 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.5 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119) clathrin adaptor complex(GO:0030131)
0.0 1.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.0 GO:0005604 basement membrane(GO:0005604)
0.0 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.7 GO:0031674 I band(GO:0031674)
0.0 1.0 GO:0030016 myofibril(GO:0030016)
0.0 0.5 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 3.7 GO:0031252 cell leading edge(GO:0031252)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 2.6 GO:0030133 transport vesicle(GO:0030133)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 2.1 GO:0005938 cell cortex(GO:0005938)
0.0 0.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 4.1 GO:0010008 endosome membrane(GO:0010008) endosomal part(GO:0044440)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 5.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267)
0.0 4.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.0 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542)
0.5 14.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.5 1.9 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.5 1.4 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.3 2.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 2.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.3 0.9 GO:0048184 obsolete follistatin binding(GO:0048184)
0.3 0.9 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.3 1.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.3 1.6 GO:0050815 phosphoserine binding(GO:0050815)
0.2 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.2 0.9 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 0.6 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.2 1.4 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.2 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 0.5 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.2 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.7 GO:0032810 sterol response element binding(GO:0032810)
0.2 15.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 1.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.8 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.4 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493) SAM domain binding(GO:0032093)
0.1 0.4 GO:0008148 obsolete negative transcription elongation factor activity(GO:0008148)
0.1 4.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 2.1 GO:0004697 protein kinase C activity(GO:0004697)
0.1 1.1 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.3 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.1 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.1 0.2 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 2.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.2 GO:0034452 dynactin binding(GO:0034452)
0.1 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 3.9 GO:0032947 protein complex scaffold(GO:0032947)
0.1 0.5 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.9 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.1 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 0.6 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 6.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 2.1 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0017163 obsolete basal transcription repressor activity(GO:0017163)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 3.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 2.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 4.2 GO:0003774 motor activity(GO:0003774)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 4.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.8 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.0 0.3 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 1.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 1.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0000149 SNARE binding(GO:0000149) syntaxin binding(GO:0019905)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.7 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0016722 oxidoreductase activity, oxidizing metal ions(GO:0016722)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004988 obsolete mu-opioid receptor activity(GO:0004988)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 2.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 12.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.2 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 2.7 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.0 1.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.5 ST_ADRENERGIC Adrenergic Pathway
0.0 0.3 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 SIG_BCR_SIGNALING_PATHWAY Members of the BCR signaling pathway