Motif ID: ZBTB16

Z-value: 0.897


Transcription factors associated with ZBTB16:

Gene SymbolEntrez IDGene Name
ZBTB16 ENSG00000109906.9 ZBTB16



Activity profile for motif ZBTB16.

activity profile for motif ZBTB16


Sorted Z-values histogram for motif ZBTB16

Sorted Z-values for motif ZBTB16



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_55562479 1.206 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr5_-_55412774 0.931 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr10_+_62538089 0.920 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1


cyclin-dependent kinase 1


chr11_-_5255861 0.867 ENST00000380299.3
HBD
hemoglobin, delta
chr10_+_5005445 0.834 ENST00000380872.4
AKR1C1
aldo-keto reductase family 1, member C1
chr6_+_26273144 0.814 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr12_+_118454500 0.782 ENST00000537315.1
ENST00000229043.3
ENST00000484086.2
ENST00000420967.1
ENST00000454402.2
ENST00000392542.2
ENST00000535092.1
RFC5






replication factor C (activator 1) 5, 36.5kDa






chr15_-_55562582 0.765 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr5_+_7654057 0.746 ENST00000537121.1
ADCY2
adenylate cyclase 2 (brain)
chr1_-_246357029 0.733 ENST00000391836.2
SMYD3
SET and MYND domain containing 3
chr1_+_198608146 0.709 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC









protein tyrosine phosphatase, receptor type, C









chr5_-_34919094 0.697 ENST00000341754.4
RAD1
RAD1 homolog (S. pombe)
chr8_-_30585439 0.628 ENST00000221130.5
GSR
glutathione reductase
chr3_-_93692781 0.625 ENST00000394236.3
PROS1
protein S (alpha)
chr10_+_5005598 0.528 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr22_+_38203898 0.524 ENST00000323205.6
ENST00000248924.6
ENST00000445195.1
GCAT


glycine C-acetyltransferase


chr21_+_40817749 0.511 ENST00000380637.3
ENST00000380634.1
ENST00000458295.1
ENST00000440288.2
ENST00000380631.1
SH3BGR




SH3 domain binding glutamic acid-rich protein




chr17_-_46623441 0.497 ENST00000330070.4
HOXB2
homeobox B2
chr2_-_11606275 0.442 ENST00000381525.3
ENST00000362009.4
E2F6

E2F transcription factor 6

chr4_+_154622652 0.440 ENST00000260010.6
TLR2
toll-like receptor 2
chr16_-_85722530 0.430 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr4_+_74301880 0.428 ENST00000395792.2
ENST00000226359.2
AFP

alpha-fetoprotein

chr4_-_99851766 0.419 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr16_+_20817761 0.414 ENST00000568046.1
ENST00000261377.6
AC004381.6

Putative RNA exonuclease NEF-sp

chr16_-_20817753 0.413 ENST00000389345.5
ENST00000300005.3
ENST00000357967.4
ENST00000569729.1
ERI2



ERI1 exoribonuclease family member 2



chr7_-_32534850 0.408 ENST00000409952.3
ENST00000409909.3
LSM5

LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr11_-_72070206 0.407 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr8_-_33370607 0.388 ENST00000360742.5
ENST00000523305.1
TTI2

TELO2 interacting protein 2

chr3_+_150126101 0.381 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr1_-_44818599 0.374 ENST00000537474.1
ERI3
ERI1 exoribonuclease family member 3
chr17_-_40134339 0.368 ENST00000587727.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr4_-_76957214 0.366 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr7_+_120591170 0.362 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr3_-_138312971 0.345 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
CEP70




centrosomal protein 70kDa




chrX_+_65382381 0.345 ENST00000519389.1
HEPH
hephaestin
chr10_+_5135981 0.345 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr3_-_138313161 0.334 ENST00000489254.1
ENST00000474781.1
ENST00000462419.1
ENST00000264982.3
CEP70



centrosomal protein 70kDa



chr9_-_21351377 0.320 ENST00000380210.1
IFNA6
interferon, alpha 6
chrX_-_23926004 0.314 ENST00000379226.4
ENST00000379220.3
APOO

apolipoprotein O

chr12_+_53836339 0.304 ENST00000549135.1
PRR13
proline rich 13
chr6_+_27925019 0.303 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr21_-_35284635 0.302 ENST00000429238.1
AP000304.12
AP000304.12
chr7_+_106505912 0.302 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr1_-_100231349 0.295 ENST00000287474.5
ENST00000414213.1
FRRS1

ferric-chelate reductase 1

chr17_-_18266797 0.293 ENST00000316694.3
ENST00000539052.1
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr19_+_36142147 0.285 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr12_+_48166978 0.281 ENST00000442218.2
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr19_-_15087839 0.280 ENST00000600144.1
SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr16_-_18908196 0.277 ENST00000565324.1
ENST00000561947.1
SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr1_-_11159887 0.270 ENST00000544779.1
ENST00000304457.7
ENST00000376936.4
EXOSC10


exosome component 10


chr12_-_113772835 0.268 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
SLC8B1



solute carrier family 8 (sodium/lithium/calcium exchanger), member B1



chr5_+_180682720 0.268 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr6_+_42749759 0.264 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chrX_+_118602363 0.264 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr9_-_15472730 0.264 ENST00000481862.1
PSIP1
PC4 and SFRS1 interacting protein 1
chr4_-_99850243 0.260 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
EIF4E



eukaryotic translation initiation factor 4E



chr15_+_75628419 0.259 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4


COMM domain containing 4


chr15_+_75628394 0.253 ENST00000564815.1
ENST00000338995.6
COMMD4

COMM domain containing 4

chr15_+_75628232 0.244 ENST00000267935.8
ENST00000567195.1
COMMD4

COMM domain containing 4

chr12_-_68696652 0.241 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr5_+_159848854 0.238 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr8_-_8318847 0.230 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr4_-_185275104 0.227 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr6_+_74171301 0.224 ENST00000415954.2
ENST00000498286.1
ENST00000370305.1
ENST00000370300.4
MTO1



mitochondrial tRNA translation optimization 1



chr1_+_15256230 0.220 ENST00000376028.4
ENST00000400798.2
KAZN

kazrin, periplakin interacting protein

chr19_+_24269981 0.205 ENST00000339642.6
ENST00000357002.4
ZNF254

zinc finger protein 254

chr19_-_23869999 0.199 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675




zinc finger protein 675




chr4_-_140223670 0.198 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr4_-_83769996 0.197 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr3_+_44840679 0.194 ENST00000425755.1
KIF15
kinesin family member 15
chr6_-_49712123 0.189 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr3_-_137893721 0.188 ENST00000505015.2
ENST00000260803.4
DBR1

debranching RNA lariats 1

chr5_+_159848807 0.185 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr12_-_21487829 0.179 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2




solute carrier organic anion transporter family, member 1A2




chr10_-_47239738 0.179 ENST00000413193.2
AGAP10
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr6_+_136172820 0.172 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr11_+_67351213 0.170 ENST00000398603.1
GSTP1
glutathione S-transferase pi 1
chr1_+_241695670 0.170 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr8_+_104831472 0.170 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr17_+_32597232 0.167 ENST00000378569.2
ENST00000200307.4
ENST00000394627.1
ENST00000394630.3
CCL7



chemokine (C-C motif) ligand 7



chr10_+_48189612 0.167 ENST00000453919.1
AGAP9
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr9_-_21239978 0.166 ENST00000380222.2
IFNA14
interferon, alpha 14
chr6_-_34639733 0.164 ENST00000374021.1
C6orf106
chromosome 6 open reading frame 106
chr8_+_104831554 0.164 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr11_+_67351019 0.163 ENST00000398606.3
GSTP1
glutathione S-transferase pi 1
chr19_+_21265028 0.159 ENST00000291770.7
ZNF714
zinc finger protein 714
chr7_-_16872932 0.158 ENST00000419572.2
ENST00000412973.1
AGR2

anterior gradient 2

chr2_+_131862872 0.156 ENST00000439822.2
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr3_-_155524049 0.152 ENST00000534941.1
ENST00000340171.2
C3orf33

chromosome 3 open reading frame 33

chrX_+_83116142 0.152 ENST00000329312.4
CYLC1
cylicin, basic protein of sperm head cytoskeleton 1
chr4_-_140223614 0.149 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr7_-_104909435 0.146 ENST00000357311.3
SRPK2
SRSF protein kinase 2
chr21_+_37692481 0.136 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr2_+_233527443 0.135 ENST00000410095.1
EFHD1
EF-hand domain family, member D1
chr19_-_45004556 0.132 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
ZNF180





zinc finger protein 180





chr19_+_13135386 0.126 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chr2_-_73520667 0.120 ENST00000545030.1
ENST00000436467.2
EGR4

early growth response 4

chr4_+_37962018 0.120 ENST00000504686.1
PTTG2
pituitary tumor-transforming 2
chr4_-_90758227 0.112 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA




synuclein, alpha (non A4 component of amyloid precursor)




chrX_+_71401526 0.110 ENST00000218432.5
ENST00000423432.2
ENST00000373669.2
PIN4


protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)


chr17_+_46908350 0.110 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2








calcium binding and coiled-coil domain 2








chr14_+_39703084 0.110 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr6_-_49712147 0.108 ENST00000433368.2
ENST00000354620.4
CRISP3

cysteine-rich secretory protein 3

chr1_+_32608566 0.107 ENST00000545542.1
KPNA6
karyopherin alpha 6 (importin alpha 7)
chr5_-_24645078 0.107 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_+_174769006 0.106 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_156095951 0.103 ENST00000448611.2
ENST00000368297.1
LMNA

lamin A/C

chr12_-_27090896 0.101 ENST00000539625.1
ENST00000538727.1
ASUN

asunder spermatogenesis regulator

chr2_-_242556900 0.100 ENST00000402545.1
ENST00000402136.1
THAP4

THAP domain containing 4

chr2_+_131862900 0.096 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
PLEKHB2


pleckstrin homology domain containing, family B (evectins) member 2


chr4_-_90758118 0.095 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr20_+_31407692 0.095 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr4_+_74606223 0.095 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr4_+_74347400 0.094 ENST00000226355.3
AFM
afamin
chr3_-_146262488 0.093 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr5_+_140220769 0.092 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr4_-_48082192 0.088 ENST00000507351.1
TXK
TXK tyrosine kinase
chr5_+_173763250 0.082 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1


RP11-267A15.1


chr15_-_74658493 0.079 ENST00000419019.2
ENST00000569662.1
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr5_+_96212185 0.075 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr17_+_61086917 0.075 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr15_-_85197501 0.072 ENST00000434634.2
WDR73
WD repeat domain 73
chr2_+_89901292 0.069 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr1_+_178310581 0.062 ENST00000462775.1
RASAL2
RAS protein activator like 2
chr19_+_45542295 0.059 ENST00000221455.3
ENST00000391953.4
ENST00000588936.1
CLASRP


CLK4-associating serine/arginine rich protein


chr3_-_164796269 0.054 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr5_-_9630463 0.053 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr16_+_81070792 0.053 ENST00000564241.1
ENST00000565237.1
ATMIN

ATM interactor

chrX_-_49089771 0.051 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F


calcium channel, voltage-dependent, L type, alpha 1F subunit


chr7_-_38289173 0.050 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr4_+_106631966 0.050 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD


glutathione S-transferase, C-terminal domain containing


chr12_-_75905374 0.048 ENST00000438169.2
ENST00000229214.4
KRR1

KRR1, small subunit (SSU) processome component, homolog (yeast)

chr15_-_74658519 0.046 ENST00000450547.1
ENST00000358632.4
CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

chr7_+_16828866 0.046 ENST00000597084.1
AC073333.1
Uncharacterized protein
chr1_+_76251879 0.043 ENST00000535300.1
ENST00000319942.3
RABGGTB

Rab geranylgeranyltransferase, beta subunit

chrX_+_115301975 0.043 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr1_-_13452656 0.042 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr2_+_102413726 0.041 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_37607497 0.041 ENST00000394287.3
ENST00000300651.6
MED1

mediator complex subunit 1

chr2_-_89310012 0.039 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chrX_+_140982452 0.039 ENST00000544766.1
MAGEC3
melanoma antigen family C, 3
chr12_+_10460549 0.038 ENST00000543420.1
ENST00000543777.1
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr16_+_19183671 0.038 ENST00000562711.2
SYT17
synaptotagmin XVII
chr3_+_46395219 0.038 ENST00000445132.2
ENST00000292301.4
CCR2

chemokine (C-C motif) receptor 2

chr17_+_21729593 0.037 ENST00000581769.1
ENST00000584755.1
UBBP4

ubiquitin B pseudogene 4

chr8_+_42552533 0.036 ENST00000289957.2
CHRNB3
cholinergic receptor, nicotinic, beta 3 (neuronal)
chr1_-_13673511 0.035 ENST00000344998.3
ENST00000334600.6
PRAMEF14

PRAME family member 14

chr5_+_67586465 0.034 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_+_7606497 0.033 ENST00000340080.4
ENST00000405785.1
ENST00000433635.1
MIOS


missing oocyte, meiosis regulator, homolog (Drosophila)


chr19_+_57640011 0.031 ENST00000598197.1
USP29
ubiquitin specific peptidase 29
chr7_-_107770794 0.031 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
LAMB4




laminin, beta 4




chr3_-_37216055 0.030 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr4_+_71108300 0.029 ENST00000304954.3
CSN3
casein kappa
chr4_+_71263599 0.028 ENST00000399575.2
PROL1
proline rich, lacrimal 1
chr13_+_76123883 0.027 ENST00000377595.3
UCHL3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr15_-_50406680 0.026 ENST00000559829.1
ATP8B4
ATPase, class I, type 8B, member 4
chr3_+_51663407 0.025 ENST00000432863.1
ENST00000296477.3
RAD54L2

RAD54-like 2 (S. cerevisiae)

chr2_+_204801471 0.025 ENST00000316386.6
ENST00000435193.1
ICOS

inducible T-cell co-stimulator

chr3_+_40518599 0.024 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
ZNF619



zinc finger protein 619



chr1_+_192605252 0.022 ENST00000391995.2
ENST00000543215.1
RGS13

regulator of G-protein signaling 13

chr19_-_19932501 0.022 ENST00000540806.2
ENST00000590766.1
ENST00000587452.1
ENST00000545006.1
ENST00000590319.1
ENST00000587461.1
ENST00000450683.2
ENST00000443905.2
ENST00000590274.1
ZNF506







CTC-559E9.4
zinc finger protein 506







CTC-559E9.4
chr16_+_89984287 0.021 ENST00000555147.1
MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr4_+_88532028 0.018 ENST00000282478.7
DSPP
dentin sialophosphoprotein
chr14_+_58754751 0.018 ENST00000598233.1
AL132989.1
AL132989.1
chr1_+_12916941 0.015 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr11_+_120255997 0.015 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr6_+_134758827 0.014 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr3_+_160394940 0.012 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr2_+_1488435 0.010 ENST00000446278.1
ENST00000469607.1
TPO

thyroid peroxidase

chrY_+_26997726 0.010 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr1_+_12851545 0.010 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr18_-_64271363 0.010 ENST00000262150.2
CDH19
cadherin 19, type 2
chr19_+_21264980 0.009 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714




zinc finger protein 714




chr4_+_96012614 0.009 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr19_-_29704448 0.008 ENST00000304863.4
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr3_-_120365866 0.007 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr12_+_21284118 0.004 ENST00000256958.2
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr3_-_15382875 0.004 ENST00000408919.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr9_+_105757590 0.003 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr3_-_146262637 0.000 ENST00000472349.1
ENST00000342435.4
PLSCR1

phospholipid scramblase 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0043316 natural killer cell activation involved in immune response(GO:0002323) cytotoxic T cell degranulation(GO:0043316) natural killer cell degranulation(GO:0043320)
0.2 0.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.2 0.5 GO:0021570 rhombomere 4 development(GO:0021570)
0.2 0.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.4 GO:0070340 cell surface pattern recognition receptor signaling pathway(GO:0002752) detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.3 GO:0071460 negative regulation of necrotic cell death(GO:0060547) cellular response to cell-matrix adhesion(GO:0071460)
0.1 1.4 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.3 GO:0071025 intracellular mRNA localization(GO:0008298) RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.3 GO:0015853 adenine transport(GO:0015853)
0.0 0.3 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.7 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.6 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0015810 C4-dicarboxylate transport(GO:0015740) aspartate transport(GO:0015810)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.6 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0090343 positive regulation of cell aging(GO:0090343)
0.0 0.4 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.4 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.7 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0075713 establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.3 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0009750 response to fructose(GO:0009750)
0.0 0.0 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.2 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.9 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.2 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 2.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0047718 indanol dehydrogenase activity(GO:0047718)
0.2 2.0 GO:0031489 myosin V binding(GO:0031489)
0.2 0.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:0070891 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.1 0.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.5 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0046934 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428) phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.0 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway