ISMARA results: ZBTB3

Motif ID: ZBTB3

Z-value: 0.598

Transcription factors associated with ZBTB3:

Gene Symbol	Entrez ID	Gene Name
ZBTB3	ENSG00000185670.7	ZBTB3

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_149688655	1.399	ENST00000461930.1 ENST00000423691.2 ENST00000490975.1 ENST00000461868.1 ENST00000452853.2	PFN2	profilin 2
chr3_-_149688502	1.346	ENST00000481767.1 ENST00000475518.1	PFN2	profilin 2
chr4_-_15939963	1.333	ENST00000259988.2	FGFBP1	fibroblast growth factor binding protein 1
chr12_-_52887034	1.309	ENST00000330722.6	KRT6A	keratin 6A
chr3_-_149688896	1.193	ENST00000239940.7	PFN2	profilin 2
chr19_+_16187085	0.857	ENST00000300933.4	TPM4	tropomyosin 4
chr2_+_202899310	0.787	ENST00000286201.1	FZD7	frizzled family receptor 7
chr5_-_82969405	0.736	ENST00000510978.1	HAPLN1	hyaluronan and proteoglycan link protein 1
chr18_-_33709268	0.500	ENST00000269187.5 ENST00000590986.1 ENST00000440549.2	SLC39A6	solute carrier family 39 (zinc transporter), member 6
chr19_-_49496557	0.456	ENST00000323798.3 ENST00000541188.1 ENST00000544287.1 ENST00000540532.1 ENST00000263276.6	GYS1	glycogen synthase 1 (muscle)
chrX_+_134166333	0.417	ENST00000257013.7	FAM127A	family with sequence similarity 127, member A
chr7_+_134576317	0.353	ENST00000424922.1 ENST00000495522.1	CALD1	caldesmon 1
chr14_-_92414055	0.316	ENST00000342058.4	FBLN5	fibulin 5
chr11_-_130786400	0.314	ENST00000265909.4	SNX19	sorting nexin 19
chr7_+_134576151	0.311	ENST00000393118.2	CALD1	caldesmon 1
chr9_-_34637718	0.308	ENST00000378892.1 ENST00000277010.4	SIGMAR1	sigma non-opioid intracellular receptor 1
chr12_-_10022735	0.292	ENST00000228438.2	CLEC2B	C-type lectin domain family 2, member B
chr17_-_10325261	0.290	ENST00000403437.2	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr13_+_27998681	0.258	ENST00000381140.4	GTF3A	general transcription factor IIIA
chr5_+_115177178	0.248	ENST00000316788.7	AP3S1	adaptor-related protein complex 3, sigma 1 subunit
chrX_+_23801280	0.219	ENST00000379251.3 ENST00000379253.3 ENST00000379254.1 ENST00000379270.4	SAT1	spermidine/spermine N1-acetyltransferase 1
chr14_-_92413353	0.215	ENST00000556154.1	FBLN5	fibulin 5
chr10_-_118032979	0.210	ENST00000355422.6	GFRA1	GDNF family receptor alpha 1
chr11_+_64692143	0.158	ENST00000164133.2 ENST00000532850.1	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr4_-_5894777	0.158	ENST00000324989.7	CRMP1	collapsin response mediator protein 1
chr17_+_7531281	0.149	ENST00000575729.1 ENST00000340624.5	SHBG	sex hormone-binding globulin
chr4_-_73935409	0.148	ENST00000507544.2 ENST00000295890.4	COX18	COX18 cytochrome C oxidase assembly factor
chr3_-_49131473	0.146	ENST00000430979.1 ENST00000357496.2 ENST00000437939.1	QRICH1	glutamine-rich 1
chr9_+_74526384	0.137	ENST00000334731.2 ENST00000377031.3	C9orf85	chromosome 9 open reading frame 85
chrX_+_152224766	0.136	ENST00000370265.4 ENST00000447306.1	PNMA3	paraneoplastic Ma antigen 3
chr18_+_32073253	0.130	ENST00000283365.9 ENST00000596745.1 ENST00000315456.6	DTNA	dystrobrevin, alpha
chrX_+_118708493	0.128	ENST00000371558.2	UBE2A	ubiquitin-conjugating enzyme E2A
chr3_-_49131013	0.116	ENST00000424300.1	QRICH1	glutamine-rich 1
chr3_-_49131788	0.114	ENST00000395443.2 ENST00000411682.1	QRICH1	glutamine-rich 1
chr6_+_30850697	0.101	ENST00000509639.1 ENST00000412274.2 ENST00000507901.1 ENST00000507046.1 ENST00000437124.2 ENST00000454612.2 ENST00000396342.2	DDR1	discoidin domain receptor tyrosine kinase 1
chr14_-_92413727	0.100	ENST00000267620.10	FBLN5	fibulin 5
chr3_-_195163803	0.090	ENST00000326793.6	ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr9_+_125132803	0.090	ENST00000540753.1	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr5_+_170288856	0.080	ENST00000523189.1	RANBP17	RAN binding protein 17
chr11_-_18548426	0.079	ENST00000357193.3 ENST00000536719.1	TSG101	tumor susceptibility 101
chr1_-_111148969	0.078	ENST00000316361.4	KCNA2	potassium voltage-gated channel, shaker-related subfamily, member 2
chr3_+_98250743	0.078	ENST00000284311.3	GPR15	G protein-coupled receptor 15
chr21_-_48024986	0.073	ENST00000291700.4 ENST00000367071.4	S100B	S100 calcium binding protein B
chr14_-_106725723	0.073	ENST00000390609.2	IGHV3-23	immunoglobulin heavy variable 3-23
chr19_-_2042065	0.066	ENST00000591588.1 ENST00000591142.1	MKNK2	MAP kinase interacting serine/threonine kinase 2
chr14_+_60715928	0.064	ENST00000395076.4	PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_-_149908710	0.062	ENST00000439741.2 ENST00000361405.6 ENST00000406732.3	MTMR11	myotubularin related protein 11
chr5_+_76506706	0.053	ENST00000340978.3 ENST00000346042.3 ENST00000264917.5 ENST00000342343.4 ENST00000333194.4	PDE8B	phosphodiesterase 8B
chr12_+_54718904	0.049	ENST00000262061.2 ENST00000549043.1 ENST00000552218.1 ENST00000553231.1 ENST00000552362.1 ENST00000455864.2 ENST00000416254.2 ENST00000549116.1 ENST00000551779.1	COPZ1	coatomer protein complex, subunit zeta 1
chr10_+_99332198	0.043	ENST00000307518.5 ENST00000298808.5 ENST00000370655.1	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)
chr20_+_54987168	0.041	ENST00000360314.3	CASS4	Cas scaffolding protein family member 4
chr2_-_136594740	0.035	ENST00000264162.2	LCT	lactase
chr8_+_22424551	0.034	ENST00000523348.1	SORBS3	sorbin and SH3 domain containing 3
chr20_+_54987305	0.032	ENST00000371336.3 ENST00000434344.1	CASS4	Cas scaffolding protein family member 4
chr1_+_160160346	0.031	ENST00000368078.3	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr5_+_74807886	0.028	ENST00000514296.1	POLK	polymerase (DNA directed) kappa
chr12_-_114843889	0.028	ENST00000405440.2	TBX5	T-box 5
chr7_-_127225620	0.024	ENST00000321407.2	GCC1	GRIP and coiled-coil domain containing 1
chrX_+_118708517	0.023	ENST00000346330.3	UBE2A	ubiquitin-conjugating enzyme E2A
chr11_-_82782861	0.016	ENST00000524635.1 ENST00000526205.1 ENST00000527633.1 ENST00000533486.1 ENST00000533276.2	RAB30	RAB30, member RAS oncogene family
chr1_+_159141397	0.016	ENST00000368124.4 ENST00000368125.4 ENST00000416746.1	CADM3	cell adhesion molecule 3
chr11_-_82782952	0.013	ENST00000534141.1	RAB30	RAB30, member RAS oncogene family
chr19_-_40023450	0.012	ENST00000326282.4	EID2B	EP300 interacting inhibitor of differentiation 2B
chr5_+_140514782	0.012	ENST00000231134.5	PCDHB5	protocadherin beta 5
chr10_+_50817141	0.008	ENST00000339797.1	CHAT	choline O-acetyltransferase
chr2_-_74570520	0.008	ENST00000394019.2 ENST00000346834.4 ENST00000359484.4 ENST00000423644.1 ENST00000377634.4 ENST00000436454.1	SLC4A5	solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr17_+_72983674	0.004	ENST00000337231.5	CDR2L	cerebellar degeneration-related protein 2-like
chr3_-_39322728	0.000	ENST00000541347.1 ENST00000412814.1	CX3CR1	chemokine (C-X3-C motif) receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.3	0.8	GO:0009996	negative regulation of cell fate specification(GO:0009996) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.2	0.6	GO:2000121	regulation of removal of superoxide radicals(GO:2000121)
0.1	1.3	GO:0007398	ectoderm development(GO:0007398)
0.0	0.1	GO:0007285	primary spermatocyte growth(GO:0007285)
0.0	3.9	GO:0008064	regulation of actin polymerization or depolymerization(GO:0008064)
0.0	0.3	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.2	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.5	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0051205	respiratory chain complex IV assembly(GO:0008535) protein insertion into membrane(GO:0051205)
0.0	1.1	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0	0.3	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0006596	polyamine biosynthetic process(GO:0006596)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0071953	elastic fiber(GO:0071953)
0.0	0.9	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	1.3	GO:0045095	keratin filament(GO:0045095)
0.0	0.8	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.5	GO:0016234	inclusion body(GO:0016234)
0.0	0.3	GO:0032982	myosin filament(GO:0032982)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.3	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	1.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.5	GO:0005536	glucose binding(GO:0005536)
0.0	0.8	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0000156	phosphorelay response regulator activity(GO:0000156)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	1.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.0	1.2	GO:0008307	structural constituent of muscle(GO:0008307)