Motif ID: ZEB1

Z-value: 7.199


Transcription factors associated with ZEB1:

Gene SymbolEntrez IDGene Name
ZEB1 ENSG00000148516.17 ZEB1



Activity profile for motif ZEB1.

activity profile for motif ZEB1


Sorted Z-values histogram for motif ZEB1

Sorted Z-values for motif ZEB1



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_38755042 18.262 ENST00000301244.7
SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_38755203 18.151 ENST00000587090.1
ENST00000454580.3
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr17_-_39942940 15.276 ENST00000310706.5
ENST00000393931.3
ENST00000424457.1
ENST00000591690.1
JUP



junction plakoglobin



chr8_+_95653427 13.506 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653373 12.936 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr8_+_95653302 12.916 ENST00000423620.2
ENST00000433389.2
ESRP1

epithelial splicing regulatory protein 1

chr1_-_209979375 12.478 ENST00000367021.3
IRF6
interferon regulatory factor 6
chr19_+_35606692 12.465 ENST00000406242.3
ENST00000454903.2
FXYD3

FXYD domain containing ion transport regulator 3

chr16_-_4987065 11.564 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr16_+_68678739 11.549 ENST00000264012.4
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_-_51504411 10.963 ENST00000593490.1
KLK8
kallikrein-related peptidase 8
chr2_-_166651191 10.912 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_183155373 10.833 ENST00000493293.1
ENST00000264144.4
LAMC2

laminin, gamma 2

chr12_-_52911718 10.813 ENST00000548409.1
KRT5
keratin 5
chr14_-_61747949 10.618 ENST00000355702.2
TMEM30B
transmembrane protein 30B
chr6_+_7541808 10.602 ENST00000379802.3
DSP
desmoplakin
chr16_+_68678892 10.544 ENST00000429102.2
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_39279838 10.511 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr1_-_153588765 10.363 ENST00000368701.1
ENST00000344616.2
S100A14

S100 calcium binding protein A14

chr6_+_7541845 10.287 ENST00000418664.2
DSP
desmoplakin
chr1_-_153588334 10.198 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr14_-_67859422 9.868 ENST00000556532.1
PLEK2
pleckstrin 2
chr1_-_153363452 9.743 ENST00000368732.1
ENST00000368733.3
S100A8

S100 calcium binding protein A8

chr4_+_75311019 9.217 ENST00000502307.1
AREG
amphiregulin
chr1_+_27189631 9.190 ENST00000339276.4
SFN
stratifin
chr19_+_35607166 9.092 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD3







FXYD domain containing ion transport regulator 3







chr19_+_35606777 8.629 ENST00000604404.1
ENST00000435734.2
ENST00000603181.1
FXYD3


FXYD domain containing ion transport regulator 3


chr4_+_75480629 8.612 ENST00000380846.3
AREGB
amphiregulin B
chr18_+_29077990 8.604 ENST00000261590.8
DSG2
desmoglein 2
chr18_+_61143994 8.474 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr17_-_39743139 8.405 ENST00000167586.6
KRT14
keratin 14
chr4_+_75310851 8.371 ENST00000395748.3
ENST00000264487.2
AREG

amphiregulin

chr19_-_10697895 8.151 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2




adaptor-related protein complex 1, mu 2 subunit




chr16_+_68679193 7.933 ENST00000581171.1
CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_35739782 7.864 ENST00000347609.4
LSR
lipolysis stimulated lipoprotein receptor
chr18_+_21269556 7.736 ENST00000399516.3
LAMA3
laminin, alpha 3
chr6_-_136871957 7.531 ENST00000354570.3
MAP7
microtubule-associated protein 7
chr14_-_61748550 7.346 ENST00000555868.1
TMEM30B
transmembrane protein 30B
chr19_+_35739597 7.316 ENST00000361790.3
LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739631 7.308 ENST00000602003.1
ENST00000360798.3
ENST00000354900.3
LSR


lipolysis stimulated lipoprotein receptor


chr14_-_67878917 7.224 ENST00000216446.4
PLEK2
pleckstrin 2
chr15_+_41136586 6.865 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr3_-_45187843 6.825 ENST00000296129.1
ENST00000425231.2
CDCP1

CUB domain containing protein 1

chr17_-_39674668 6.792 ENST00000393981.3
KRT15
keratin 15
chr8_+_102504651 6.781 ENST00000251808.3
ENST00000521085.1
GRHL2

grainyhead-like 2 (Drosophila)

chr19_-_12886327 6.616 ENST00000397668.3
ENST00000587178.1
ENST00000264827.5
HOOK2


hook microtubule-tethering protein 2


chr5_+_76114758 6.585 ENST00000514165.1
ENST00000296677.4
F2RL1

coagulation factor II (thrombin) receptor-like 1

chr16_+_68771128 6.477 ENST00000261769.5
ENST00000422392.2
CDH1

cadherin 1, type 1, E-cadherin (epithelial)

chr19_+_35739897 6.134 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
LSR


lipolysis stimulated lipoprotein receptor


chr14_-_65409438 6.128 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr11_+_394196 6.020 ENST00000331563.2
ENST00000531857.1
PKP3

plakophilin 3

chr12_-_6484715 5.942 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr2_-_20424844 5.850 ENST00000403076.1
ENST00000254351.4
SDC1

syndecan 1

chr19_+_35739280 5.787 ENST00000602122.1
LSR
lipolysis stimulated lipoprotein receptor
chr12_+_52626898 5.762 ENST00000331817.5
KRT7
keratin 7
chr17_+_73717551 5.521 ENST00000450894.3
ITGB4
integrin, beta 4
chr19_-_51522955 5.464 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr1_+_152956549 5.344 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr21_-_43187231 5.271 ENST00000332512.3
ENST00000352483.2
RIPK4

receptor-interacting serine-threonine kinase 4

chr1_-_59043166 5.242 ENST00000371225.2
TACSTD2
tumor-associated calcium signal transducer 2
chr22_+_45148432 5.190 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8




Rho GTPase activating protein 8




chr6_-_10419871 5.161 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_-_112260531 5.116 ENST00000374541.2
ENST00000262539.3
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr14_-_65409502 5.070 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_-_20425158 5.027 ENST00000381150.1
SDC1
syndecan 1
chr1_-_201368653 4.879 ENST00000367313.3
LAD1
ladinin 1
chr16_-_68269971 4.864 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr17_+_73717407 4.833 ENST00000579662.1
ITGB4
integrin, beta 4
chr1_-_201368707 4.795 ENST00000391967.2
LAD1
ladinin 1
chr10_+_47746929 4.791 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr4_+_85504075 4.651 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_152957707 4.586 ENST00000368762.1
SPRR1A
small proline-rich protein 1A
chr11_+_706113 4.579 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8L2


EPS8-like 2


chr15_+_41136216 4.518 ENST00000562057.1
ENST00000344051.4
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr1_-_207206092 4.477 ENST00000359470.5
ENST00000461135.2
C1orf116

chromosome 1 open reading frame 116

chr8_+_32406179 4.292 ENST00000405005.3
NRG1
neuregulin 1
chr12_-_48298785 4.284 ENST00000550325.1
ENST00000546653.1
ENST00000549336.1
ENST00000535672.1
ENST00000229022.3
ENST00000548664.1
VDR





vitamin D (1,25- dihydroxyvitamin D3) receptor





chr1_+_60280458 4.275 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr11_-_118134997 4.246 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr5_-_1882858 4.226 ENST00000511126.1
ENST00000231357.2
IRX4

iroquois homeobox 4

chr8_-_49833978 4.194 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_-_95007193 4.183 ENST00000370207.4
ENST00000334047.7
F3

coagulation factor III (thromboplastin, tissue factor)

chr6_+_30850697 4.175 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1






discoidin domain receptor tyrosine kinase 1






chrX_+_105969893 4.091 ENST00000255499.2
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr11_+_121322832 4.066 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_+_173292280 4.045 ENST00000264107.7
ITGA6
integrin, alpha 6
chr14_-_24036943 3.955 ENST00000556843.1
ENST00000397120.3
ENST00000557189.1
AP1G2


adaptor-related protein complex 1, gamma 2 subunit


chr2_+_173292390 3.945 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr2_+_173292301 3.876 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6


integrin, alpha 6


chr1_+_153330322 3.868 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr8_+_86376081 3.865 ENST00000285379.5
CA2
carbonic anhydrase II
chr7_+_116166331 3.784 ENST00000393468.1
ENST00000393467.1
CAV1

caveolin 1, caveolae protein, 22kDa

chr1_+_35220613 3.780 ENST00000338513.1
GJB5
gap junction protein, beta 5, 31.1kDa
chr7_+_18535786 3.746 ENST00000406072.1
HDAC9
histone deacetylase 9
chr1_+_156030937 3.745 ENST00000361084.5
RAB25
RAB25, member RAS oncogene family
chr18_-_74844713 3.741 ENST00000397860.3
MBP
myelin basic protein
chr19_-_51523275 3.709 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr2_+_47596287 3.679 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr8_-_81083341 3.660 ENST00000519303.2
TPD52
tumor protein D52
chr1_+_44401479 3.657 ENST00000438616.3
ARTN
artemin
chr11_-_65667997 3.653 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr14_-_51411146 3.627 ENST00000532462.1
PYGL
phosphorylase, glycogen, liver
chr17_+_74372662 3.618 ENST00000591651.1
ENST00000545180.1
SPHK1

sphingosine kinase 1

chr3_+_142315225 3.617 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr12_+_57984965 3.612 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr11_+_66824276 3.610 ENST00000308831.2
RHOD
ras homolog family member D
chr2_-_235405168 3.561 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chr1_+_1981890 3.545 ENST00000378567.3
ENST00000468310.1
PRKCZ

protein kinase C, zeta

chr12_-_53298841 3.519 ENST00000293308.6
KRT8
keratin 8
chr14_-_51411194 3.484 ENST00000544180.2
PYGL
phosphorylase, glycogen, liver
chr17_+_73717516 3.475 ENST00000200181.3
ENST00000339591.3
ITGB4

integrin, beta 4

chr19_-_51456198 3.453 ENST00000594846.1
KLK5
kallikrein-related peptidase 5
chr12_-_6484376 3.407 ENST00000360168.3
ENST00000358945.3
SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

chr14_+_75745477 3.392 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr8_+_31497271 3.373 ENST00000520407.1
NRG1
neuregulin 1
chr2_-_220118631 3.336 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chrX_+_131157322 3.333 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
MST4


Serine/threonine-protein kinase MST4


chr16_+_57653854 3.328 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56



G protein-coupled receptor 56



chr17_+_73521763 3.311 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2




lethal giant larvae homolog 2 (Drosophila)




chr11_+_32851487 3.277 ENST00000257836.3
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr18_-_28682374 3.223 ENST00000280904.6
DSC2
desmocollin 2
chr11_+_69924397 3.189 ENST00000355303.5
ANO1
anoctamin 1, calcium activated chloride channel
chr6_+_30851840 3.177 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
DDR1





discoidin domain receptor tyrosine kinase 1





chr6_-_128841503 3.169 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK







protein tyrosine phosphatase, receptor type, K







chr5_+_148206156 3.136 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr18_-_28681950 3.120 ENST00000251081.6
DSC2
desmocollin 2
chr7_+_144052381 3.117 ENST00000498580.1
ENST00000056217.5
ARHGEF5

Rho guanine nucleotide exchange factor (GEF) 5

chr14_-_105635090 3.086 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr6_+_30852130 3.083 ENST00000428153.2
ENST00000376568.3
ENST00000452441.1
ENST00000515219.1
DDR1



discoidin domain receptor tyrosine kinase 1



chr1_+_26503894 3.082 ENST00000361530.6
ENST00000374253.5
CNKSR1

connector enhancer of kinase suppressor of Ras 1

chr16_+_57653989 3.068 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56



G protein-coupled receptor 56



chr6_+_53659746 3.062 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr17_-_38657849 3.010 ENST00000254051.6
TNS4
tensin 4
chr11_-_65667884 2.985 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr1_+_44399466 2.972 ENST00000498139.2
ENST00000491846.1
ARTN

artemin

chr2_+_234602305 2.964 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_+_112375275 2.957 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WISP3


WNT1 inducible signaling pathway protein 3


chr2_+_17721920 2.950 ENST00000295156.4
VSNL1
visinin-like 1
chrX_-_8700171 2.923 ENST00000262648.3
KAL1
Kallmann syndrome 1 sequence
chr17_+_48133459 2.910 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr4_+_74735102 2.906 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr8_-_81083890 2.885 ENST00000518937.1
TPD52
tumor protein D52
chr4_-_143767428 2.878 ENST00000513000.1
ENST00000509777.1
ENST00000503927.1
INPP4B


inositol polyphosphate-4-phosphatase, type II, 105kDa


chr1_+_44398943 2.844 ENST00000372359.5
ENST00000414809.3
ARTN

artemin

chr16_-_28550320 2.803 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr2_+_102608306 2.795 ENST00000332549.3
IL1R2
interleukin 1 receptor, type II
chr11_-_112034803 2.781 ENST00000528832.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr12_+_66217911 2.750 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr2_-_235405679 2.743 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr12_-_33049690 2.716 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chr1_+_32042105 2.715 ENST00000457433.2
ENST00000441210.2
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_+_32042131 2.686 ENST00000271064.7
ENST00000537531.1
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr11_-_112034780 2.631 ENST00000524595.1
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr16_+_56598961 2.628 ENST00000219162.3
MT4
metallothionein 4
chr19_-_6767431 2.628 ENST00000437152.3
ENST00000597687.1
SH2D3A

SH2 domain containing 3A

chr14_+_105331596 2.623 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B



centrosomal protein 170B



chr19_+_8429031 2.621 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4


angiopoietin-like 4


chr11_-_112034831 2.599 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr5_+_167718604 2.584 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr9_-_112083229 2.550 ENST00000374566.3
ENST00000374557.4
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr3_-_32022733 2.512 ENST00000438237.2
ENST00000396556.2
OSBPL10

oxysterol binding protein-like 10

chr4_+_89299885 2.472 ENST00000380265.5
ENST00000273960.3
HERC6

HECT and RLD domain containing E3 ubiquitin protein ligase family member 6

chr11_+_66824346 2.404 ENST00000532559.1
RHOD
ras homolog family member D
chr21_+_39628852 2.399 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_115850547 2.393 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
TES


testis derived transcript (3 LIM domains)


chr7_+_16793160 2.365 ENST00000262067.4
TSPAN13
tetraspanin 13
chr3_+_142342228 2.359 ENST00000337777.3
PLS1
plastin 1
chr2_-_165477971 2.357 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr17_-_39769005 2.339 ENST00000301653.4
ENST00000593067.1
KRT16

keratin 16

chr12_-_50677255 2.333 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIMA1


LIM domain and actin binding 1


chr10_+_124134201 2.324 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1



pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1



chr4_+_4388805 2.315 ENST00000504171.1
NSG1
Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.
chr20_+_44035200 2.297 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr19_-_51471362 2.290 ENST00000376853.4
ENST00000424910.2
KLK6

kallikrein-related peptidase 6

chr1_-_160990886 2.265 ENST00000537746.1
F11R
F11 receptor
chr17_+_52978107 2.258 ENST00000445275.2
TOM1L1
target of myb1 (chicken)-like 1
chr17_+_52978156 2.251 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chr1_-_186649543 2.241 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr21_+_39628655 2.231 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15



potassium inwardly-rectifying channel, subfamily J, member 15



chr4_+_89299994 2.219 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr11_+_59522532 2.209 ENST00000337979.4
ENST00000535361.1
STX3

syntaxin 3

chrX_+_131157290 2.208 ENST00000394334.2
MST4
Serine/threonine-protein kinase MST4
chr19_-_51472222 2.199 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chr17_-_7165662 2.196 ENST00000571881.2
ENST00000360325.7
CLDN7

claudin 7

chr19_-_6767516 2.185 ENST00000245908.6
SH2D3A
SH2 domain containing 3A
chr13_+_73632897 2.180 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr3_-_50336278 2.178 ENST00000359051.3
ENST00000417393.1
ENST00000442620.1
ENST00000452674.1
HYAL3
NAT6


hyaluronoglucosaminidase 3
N-acetyltransferase 6 (GCN5-related)


chr7_+_116165754 2.129 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr10_-_118764862 2.123 ENST00000260777.10
KIAA1598
KIAA1598
chr8_+_11660227 2.106 ENST00000443614.2
ENST00000525900.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr19_-_51472031 2.095 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr17_-_76975925 2.094 ENST00000591274.1
ENST00000589906.1
ENST00000591778.1
ENST00000589775.2
ENST00000585407.1
ENST00000262776.3
LGALS3BP





lectin, galactoside-binding, soluble, 3 binding protein





chr3_-_69435224 2.080 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chr18_+_55862622 2.079 ENST00000456173.2
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr14_+_59655369 2.077 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1


dishevelled associated activator of morphogenesis 1


chr18_+_47088401 2.071 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr8_-_110656995 2.058 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr9_-_110251836 2.055 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr19_-_51471381 2.051 ENST00000594641.1
KLK6
kallikrein-related peptidase 6
chr19_+_45281118 2.045 ENST00000270279.3
ENST00000341505.4
CBLC

Cbl proto-oncogene C, E3 ubiquitin protein ligase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.3 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
3.7 11.0 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
3.6 10.9 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
3.6 10.9 GO:0048627 myoblast development(GO:0048627)
3.5 14.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
3.2 22.2 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
2.9 5.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
2.6 2.6 GO:0035330 regulation of hippo signaling(GO:0035330)
2.2 64.4 GO:0031581 hemidesmosome assembly(GO:0031581)
2.1 6.2 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.0 8.0 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
1.7 5.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
1.7 5.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.7 6.6 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
1.4 5.6 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
1.3 22.9 GO:0043616 keratinocyte proliferation(GO:0043616)
1.3 5.2 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
1.2 6.1 GO:0001661 conditioned taste aversion(GO:0001661)
1.2 3.6 GO:0046521 sphingoid catabolic process(GO:0046521)
1.2 5.9 GO:0044854 membrane raft assembly(GO:0001765) nitric oxide homeostasis(GO:0033484) negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
1.2 3.5 GO:0009635 response to herbicide(GO:0009635)
1.1 2.2 GO:0031394 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
1.1 9.9 GO:1903519 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
1.1 3.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.1 5.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
1.0 3.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
1.0 1.0 GO:0046110 xanthine metabolic process(GO:0046110)
1.0 10.7 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
1.0 3.9 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.9 3.7 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.9 4.5 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.9 2.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.9 1.7 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.9 9.5 GO:0002544 chronic inflammatory response(GO:0002544)
0.9 10.3 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.8 44.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.8 8.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.8 3.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.8 4.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.8 23.5 GO:0031424 keratinization(GO:0031424)
0.7 4.5 GO:0009649 entrainment of circadian clock(GO:0009649)
0.7 21.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.7 7.9 GO:0016540 protein autoprocessing(GO:0016540)
0.7 2.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7 2.0 GO:0046368 GDP-L-fucose biosynthetic process(GO:0042350) 'de novo' GDP-L-fucose biosynthetic process(GO:0042351) GDP-L-fucose metabolic process(GO:0046368)
0.6 2.6 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.6 1.3 GO:0060061 Spemann organizer formation(GO:0060061)
0.6 0.6 GO:0060539 diaphragm development(GO:0060539)
0.6 1.9 GO:0060896 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.6 3.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.6 1.8 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.6 3.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.5 0.5 GO:0045844 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.5 1.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 0.5 GO:1900087 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.5 1.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.5 1.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.5 11.4 GO:0060444 branching involved in mammary gland duct morphogenesis(GO:0060444)
0.5 3.5 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.5 2.0 GO:0001807 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) regulation of phosphatidylinositol biosynthetic process(GO:0010511) obsolete regulation of calcium ion transport via store-operated calcium channel activity(GO:0032234) regulation of phospholipid biosynthetic process(GO:0071071)
0.5 1.0 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.5 0.9 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.5 1.4 GO:0070254 mucus secretion(GO:0070254)
0.5 4.1 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.5 1.4 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.4 0.4 GO:1901142 insulin processing(GO:0030070) insulin metabolic process(GO:1901142)
0.4 0.9 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.4 2.2 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.4 11.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 2.5 GO:0034201 response to oleic acid(GO:0034201)
0.4 2.5 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.4 2.1 GO:0060325 face morphogenesis(GO:0060325)
0.4 30.1 GO:0006821 chloride transport(GO:0006821)
0.4 52.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 9.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.4 2.4 GO:0060056 mammary gland involution(GO:0060056)
0.4 1.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.4 0.4 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.4 3.5 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.4 2.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.4 30.5 GO:0001889 liver development(GO:0001889)
0.4 5.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.4 1.9 GO:0031639 plasminogen activation(GO:0031639)
0.4 1.5 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.4 0.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4 17.1 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.4 10.0 GO:0007405 neuroblast proliferation(GO:0007405)
0.4 2.8 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.4 6.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.4 1.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 3.5 GO:0050919 negative chemotaxis(GO:0050919)
0.3 2.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 1.3 GO:0072180 nephric duct development(GO:0072176) mesonephric duct development(GO:0072177) nephric duct morphogenesis(GO:0072178) mesonephric duct morphogenesis(GO:0072180)
0.3 1.7 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.3 1.0 GO:0071476 response to vitamin B1(GO:0010266) cellular hypotonic response(GO:0071476)
0.3 1.0 GO:1904396 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.3 4.5 GO:0032456 endocytic recycling(GO:0032456)
0.3 1.3 GO:0051409 response to nitrosative stress(GO:0051409)
0.3 0.9 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.3 2.5 GO:0019388 galactose catabolic process(GO:0019388)
0.3 0.9 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.3 1.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.3 0.3 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.3 0.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.3 0.9 GO:0030205 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.3 1.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.3 8.9 GO:0050909 sensory perception of taste(GO:0050909)
0.3 5.3 GO:0050927 positive regulation of positive chemotaxis(GO:0050927)
0.3 0.6 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.3 0.8 GO:0048878 chemical homeostasis(GO:0048878)
0.3 0.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.3 1.6 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.3 1.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.2 2.0 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.2 30.9 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.2 1.5 GO:0030041 actin filament polymerization(GO:0030041)
0.2 0.5 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.2 0.2 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.2 1.4 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 1.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 1.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 1.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.2 0.7 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.2 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 0.7 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 0.6 GO:0060612 adipose tissue development(GO:0060612)
0.2 3.0 GO:0035315 hair cell differentiation(GO:0035315)
0.2 1.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.2 1.9 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.2 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.2 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.2 0.6 GO:0010041 response to iron(III) ion(GO:0010041) positive regulation of histone phosphorylation(GO:0033129) response to DDT(GO:0046680) regulation of chromosome condensation(GO:0060623) cellular response to iron ion(GO:0071281) cellular response to iron(III) ion(GO:0071283)
0.2 0.4 GO:0055078 sodium ion homeostasis(GO:0055078)
0.2 2.6 GO:0007032 endosome organization(GO:0007032)
0.2 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.2 0.2 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.2 1.4 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2 0.2 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.2 0.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 2.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.6 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 1.8 GO:0043113 receptor clustering(GO:0043113)
0.2 2.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.2 4.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.2 1.1 GO:0006935 chemotaxis(GO:0006935) taxis(GO:0042330)
0.2 2.3 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.2 1.0 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2 1.6 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.2 0.5 GO:0006106 fumarate metabolic process(GO:0006106)
0.2 2.4 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2 0.8 GO:0048840 otolith development(GO:0048840)
0.2 1.2 GO:0007549 dosage compensation(GO:0007549)
0.2 0.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.2 5.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 0.8 GO:0046836 glycolipid transport(GO:0046836)
0.2 0.6 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 0.3 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.2 0.5 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.2 1.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 0.5 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.2 1.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 0.5 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting two-sector ATPase complex assembly(GO:0070071) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 3.6 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.4 GO:0000050 urea cycle(GO:0000050)
0.1 1.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.3 GO:0042311 vasodilation(GO:0042311)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.6 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.4 GO:0031268 pseudopodium organization(GO:0031268)
0.1 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.1 GO:0044764 multi-organism cellular process(GO:0044764)
0.1 2.9 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.1 0.6 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.8 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.3 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 1.8 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.1 0.4 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 3.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 1.2 GO:0051014 actin filament severing(GO:0051014)
0.1 1.1 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.5 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.1 2.0 GO:0007398 ectoderm development(GO:0007398)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 4.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 1.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.0 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.1 0.9 GO:0016559 peroxisome membrane biogenesis(GO:0016557) peroxisome fission(GO:0016559)
0.1 2.1 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 1.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0048075 regulation of eye pigmentation(GO:0048073) positive regulation of eye pigmentation(GO:0048075)
0.1 0.5 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of epidermis development(GO:0045684) positive regulation of hair follicle development(GO:0051798)
0.1 1.0 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.2 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.1 2.0 GO:0031529 ruffle organization(GO:0031529)
0.1 0.4 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1 0.3 GO:0060438 trachea development(GO:0060438)
0.1 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 2.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.1 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.3 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.1 0.3 GO:0034126 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) positive regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034126)
0.1 0.7 GO:1902667 regulation of axon extension involved in axon guidance(GO:0048841) regulation of axon guidance(GO:1902667)
0.1 6.6 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.1 0.4 GO:0051890 regulation of cardioblast differentiation(GO:0051890) regulation of cardiocyte differentiation(GO:1905207)
0.1 0.4 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.1 0.3 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.5 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858)
0.1 0.7 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037)
0.1 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 1.0 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.1 0.9 GO:0006546 glycine catabolic process(GO:0006546)
0.1 1.1 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.1 0.6 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 0.3 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 1.4 GO:0015884 folic acid transport(GO:0015884)
0.1 0.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.3 GO:0060295 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium-dependent cell motility(GO:0060285) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of microtubule-based movement(GO:0060632) regulation of cilium-dependent cell motility(GO:1902019)
0.1 1.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.1 0.3 GO:0070633 transepithelial transport(GO:0070633)
0.1 1.6 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 4.1 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 0.8 GO:0055075 potassium ion homeostasis(GO:0055075)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 0.2 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.5 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.1 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.2 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.1 0.2 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.2 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.1 0.4 GO:0015791 polyol transport(GO:0015791)
0.1 0.3 GO:0060363 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cranial suture morphogenesis(GO:0060363) cellular response to sterol depletion(GO:0071501) craniofacial suture morphogenesis(GO:0097094)
0.1 0.8 GO:0006702 androgen biosynthetic process(GO:0006702)
0.1 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 0.9 GO:0050704 regulation of interleukin-1 secretion(GO:0050704) positive regulation of interleukin-1 secretion(GO:0050716)
0.1 1.6 GO:0016042 lipid catabolic process(GO:0016042)
0.1 0.2 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661) negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 3.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.4 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.1 1.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.1 GO:0010332 response to gamma radiation(GO:0010332)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 2.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 0.3 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183)
0.1 1.1 GO:0006954 inflammatory response(GO:0006954)
0.1 0.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0043030 regulation of macrophage activation(GO:0043030)
0.1 2.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 3.1 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.0 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.1 0.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.1 0.1 GO:0048715 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.2 GO:0051608 histamine transport(GO:0051608)
0.1 0.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.2 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.1 0.2 GO:0060674 placenta blood vessel development(GO:0060674)
0.1 1.8 GO:0007613 memory(GO:0007613)
0.1 1.7 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.1 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.2 GO:0060123 regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1 1.0 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.3 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.1 1.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.7 GO:0006672 ceramide metabolic process(GO:0006672)
0.1 0.4 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.1 1.2 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.4 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.9 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0051216 cartilage development(GO:0051216)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.7 GO:0007632 visual behavior(GO:0007632)
0.0 0.2 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.9 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.3 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.5 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.6 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.3 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0090594 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 2.2 GO:0042552 myelination(GO:0042552)
0.0 3.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.3 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 3.8 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 5.2 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:0016101 retinoid metabolic process(GO:0001523) diterpenoid metabolic process(GO:0016101)
0.0 2.3 GO:0008544 epidermis development(GO:0008544)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.9 GO:0006909 phagocytosis(GO:0006909)
0.0 0.2 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0006200 obsolete ATP catabolic process(GO:0006200)
0.0 0.3 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0015893 drug transport(GO:0015893)
0.0 0.7 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 1.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.5 GO:0061025 membrane fusion(GO:0061025)
0.0 0.3 GO:0006928 movement of cell or subcellular component(GO:0006928)
0.0 0.1 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 2.4 GO:0006921 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:1901998 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.4 GO:0042255 ribosome assembly(GO:0042255)
0.0 1.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 1.6 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.8 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.0 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.2 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.5 GO:0007030 Golgi organization(GO:0007030)
0.0 0.9 GO:0007338 single fertilization(GO:0007338)
0.0 0.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0046210 nitric oxide catabolic process(GO:0046210)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0015838 quaternary ammonium group transport(GO:0015697) amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0030826 regulation of cGMP biosynthetic process(GO:0030826)
0.0 0.4 GO:0031055 DNA replication-independent nucleosome assembly(GO:0006336) chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.8 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.4 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:1901019 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314) regulation of calcium ion transmembrane transporter activity(GO:1901019) regulation of cation channel activity(GO:2001257)
0.0 0.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0001947 heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143) determination of heart left/right asymmetry(GO:0061371)
0.0 0.1 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.0 0.3 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.1 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173) ERBB signaling pathway(GO:0038127)
0.0 0.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0045926 negative regulation of growth(GO:0045926)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0099515 nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0008306 associative learning(GO:0008306)
0.0 0.6 GO:0030521 androgen receptor signaling pathway(GO:0030521)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.7 11.2 GO:0005607 laminin-2 complex(GO:0005607)
3.4 37.3 GO:0005916 fascia adherens(GO:0005916)
2.7 10.7 GO:0070695 FHF complex(GO:0070695)
1.7 40.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.6 36.7 GO:0030057 desmosome(GO:0030057)
1.5 6.1 GO:0016342 catenin complex(GO:0016342)
1.0 17.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.9 3.6 GO:0033269 internode region of axon(GO:0033269)
0.9 1.8 GO:0005899 insulin receptor complex(GO:0005899)
0.8 3.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.8 9.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.8 30.1 GO:0045095 keratin filament(GO:0045095)
0.7 28.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.7 4.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.7 8.7 GO:0005606 laminin-1 complex(GO:0005606)
0.6 5.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.6 2.3 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.6 25.8 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.5 2.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5 9.9 GO:0001533 cornified envelope(GO:0001533)
0.4 7.9 GO:0034706 sodium channel complex(GO:0034706)
0.4 4.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 2.0 GO:0002080 acrosomal membrane(GO:0002080)
0.4 1.8 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.4 28.8 GO:0034707 chloride channel complex(GO:0034707)
0.3 1.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 10.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 5.0 GO:0005922 connexon complex(GO:0005922)
0.3 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.5 GO:0032449 CBM complex(GO:0032449)
0.3 1.5 GO:0019718 obsolete rough microsome(GO:0019718)
0.3 1.7 GO:0071437 invadopodium(GO:0071437)
0.3 7.1 GO:0009925 basal plasma membrane(GO:0009925)
0.3 3.7 GO:0031143 pseudopodium(GO:0031143)
0.2 1.2 GO:0001740 Barr body(GO:0001740)
0.2 5.0 GO:0005902 microvillus(GO:0005902)
0.2 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 0.8 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 2.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.2 1.0 GO:0042599 lamellar body(GO:0042599)
0.2 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 10.5 GO:0005882 intermediate filament(GO:0005882)
0.2 5.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 1.1 GO:0051233 spindle midzone(GO:0051233)
0.2 0.8 GO:0005602 complement component C1 complex(GO:0005602)
0.2 0.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.5 GO:0030673 axolemma(GO:0030673)
0.2 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 8.4 GO:0042734 presynaptic membrane(GO:0042734)
0.1 4.5 GO:0030175 filopodium(GO:0030175)
0.1 18.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.4 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.1 0.8 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 9.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 2.5 GO:0030424 axon(GO:0030424)
0.1 0.9 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 3.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 1.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.1 7.0 GO:0035097 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.1 0.9 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 47.7 GO:0005625 obsolete soluble fraction(GO:0005625)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0000805 X chromosome(GO:0000805)
0.1 11.6 GO:0005911 cell-cell junction(GO:0005911)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 18.2 GO:0005792 obsolete microsome(GO:0005792)
0.1 59.7 GO:0005615 extracellular space(GO:0005615)
0.1 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.3 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0031526 brush border membrane(GO:0031526)
0.1 0.5 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 2.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.3 GO:0032838 cell projection cytoplasm(GO:0032838) dendrite cytoplasm(GO:0032839)
0.0 0.9 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.5 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:1903561 extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.6 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.1 GO:0019717 obsolete synaptosome(GO:0019717)
0.0 0.2 GO:0000803 sex chromosome(GO:0000803) XY body(GO:0001741)
0.0 0.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 11.3 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 2.3 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.5 GO:0030139 endocytic vesicle(GO:0030139)
0.0 9.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.2 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 23.3 GO:0005576 extracellular region(GO:0005576)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 23.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 4.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.1 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 22.3 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
1.8 7.3 GO:0002060 purine nucleobase binding(GO:0002060)
1.6 4.7 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
1.4 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
1.2 3.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
1.2 10.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
1.1 7.4 GO:0001784 phosphotyrosine binding(GO:0001784)
1.0 3.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.0 9.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.0 3.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.9 5.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.9 27.5 GO:0051117 ATPase binding(GO:0051117)
0.8 3.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.8 5.6 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
0.8 3.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.8 3.9 GO:0005499 vitamin D binding(GO:0005499)
0.7 13.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.7 2.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.7 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.6 9.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 3.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.6 1.8 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.6 3.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.6 2.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.6 59.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.5 2.7 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.5 1.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.5 1.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) exoribonuclease II activity(GO:0008859)
0.5 1.6 GO:0030151 molybdenum ion binding(GO:0030151)
0.5 3.1 GO:0005112 Notch binding(GO:0005112)
0.5 2.5 GO:0003680 AT DNA binding(GO:0003680)
0.5 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.5 6.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.5 52.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.5 5.4 GO:0050780 dopamine receptor binding(GO:0050780)
0.4 2.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.4 2.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.4 3.8 GO:1901567 icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.4 4.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.4 1.2 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.4 42.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.4 0.4 GO:0005113 patched binding(GO:0005113)
0.4 1.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.4 21.5 GO:0042379 chemokine receptor binding(GO:0042379)
0.4 1.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 1.9 GO:0080030 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.4 1.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.4 3.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.4 4.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.3 6.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.3 1.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160) protein phosphatase activator activity(GO:0072542)
0.3 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.3 1.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 0.9 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.3 7.5 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.3 4.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 0.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.3 2.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.3 5.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.7 GO:0045545 syndecan binding(GO:0045545)
0.3 1.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 4.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.3 1.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 0.8 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.3 1.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 0.8 GO:0051765 obsolete inositol-1,3,4-trisphosphate 5/6-kinase activity(GO:0035300) inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765)
0.3 1.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 0.8 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0070548 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847) L-glutamine aminotransferase activity(GO:0070548)
0.3 1.8 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.2 1.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.7 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.2 1.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 2.5 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 7.6 GO:0002020 protease binding(GO:0002020)
0.2 6.2 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.2 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.6 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 1.1 GO:0004741 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724) [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.6 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2 0.6 GO:0032190 acrosin binding(GO:0032190)
0.2 0.8 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.2 0.6 GO:0035173 histone kinase activity(GO:0035173)
0.2 4.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 0.6 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.2 0.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 2.3 GO:0005243 gap junction channel activity(GO:0005243)
0.2 3.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 5.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 1.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 0.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 32.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 3.8 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.2 0.7 GO:0030276 clathrin binding(GO:0030276)
0.2 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 1.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 0.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.2 4.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.8 GO:0017089 glycolipid transporter activity(GO:0017089)
0.2 0.5 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.2 3.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 4.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.2 0.6 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.0 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 1.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 1.0 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 4.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 8.3 GO:0008201 heparin binding(GO:0008201)
0.1 2.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.1 2.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0019956 chemokine binding(GO:0019956)
0.1 0.9 GO:0050733 RS domain binding(GO:0050733)
0.1 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 22.7 GO:0008083 growth factor activity(GO:0008083)
0.1 5.4 GO:0001948 glycoprotein binding(GO:0001948)
0.1 0.5 GO:0046980 oligopeptide-transporting ATPase activity(GO:0015421) tapasin binding(GO:0046980)
0.1 0.6 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 0.9 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.3 GO:0043236 laminin binding(GO:0043236)
0.1 0.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.1 2.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0070513 death domain binding(GO:0070513)
0.1 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 6.8 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 1.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.9 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 4.1 GO:0043130 ubiquitin binding(GO:0043130)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0010181 FMN binding(GO:0010181)
0.1 0.6 GO:0000293 ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 0.2 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 2.1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.4 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 43.6 GO:0005198 structural molecule activity(GO:0005198)
0.1 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 1.4 GO:0005542 folic acid binding(GO:0005542)
0.1 1.3 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.4 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236) tau-protein kinase activity(GO:0050321)
0.1 0.5 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.1 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 46.2 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.6 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.8 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.5 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.6 GO:0031014 troponin T binding(GO:0031014)
0.1 1.9 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.8 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 2.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 0.3 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.1 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.2 GO:0030172 troponin C binding(GO:0030172)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 5.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 2.1 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.2 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.4 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.4 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 2.1 GO:0008017 microtubule binding(GO:0008017)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 5.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.7 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 12.6 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.8 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 3.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 4.1 GO:0004871 signal transducer activity(GO:0004871)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.9 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 16.0 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 0.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0015631 tubulin binding(GO:0015631)
0.0 0.0 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0043176 amine binding(GO:0043176)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 13.5 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071)
0.0 0.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.7 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.2 18.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.2 5.1 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 5.4 ST_GA12_PATHWAY G alpha 12 Pathway
0.1 1.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.6 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.1 1.1 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.0 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 2.7 SIG_CD40PATHWAYMAP Genes related to CD40 signaling
0.1 2.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 ST_P38_MAPK_PATHWAY p38 MAPK Pathway