Motif ID: ZIC1

Z-value: 0.707


Transcription factors associated with ZIC1:

Gene SymbolEntrez IDGene Name
ZIC1 ENSG00000152977.5 ZIC1



Activity profile for motif ZIC1.

activity profile for motif ZIC1


Sorted Z-values histogram for motif ZIC1

Sorted Z-values for motif ZIC1



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_78622805 1.094 ENST00000373298.2
ITM2A
integral membrane protein 2A
chr19_-_3028354 0.887 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr16_+_771663 0.740 ENST00000568916.1
FAM173A
family with sequence similarity 173, member A
chr1_+_65775204 0.714 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_+_233749739 0.646 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr13_-_29069232 0.582 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1


fms-related tyrosine kinase 1


chr4_-_109090106 0.550 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr1_-_71513471 0.534 ENST00000370931.3
ENST00000356595.4
ENST00000306666.5
ENST00000370932.2
ENST00000351052.5
ENST00000414819.1
ENST00000370924.4
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr1_-_1711508 0.500 ENST00000378625.1
NADK
NAD kinase
chr18_-_52989525 0.485 ENST00000457482.3
TCF4
transcription factor 4
chr10_-_36813162 0.485 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr1_+_89990431 0.484 ENST00000330947.2
ENST00000358200.4
LRRC8B

leucine rich repeat containing 8 family, member B

chr18_-_52989217 0.460 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_24120143 0.438 ENST00000374501.1
LYPLA2
lysophospholipase II
chr16_+_2521500 0.431 ENST00000293973.1
NTN3
netrin 3
chr10_-_62493223 0.430 ENST00000373827.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_+_134975753 0.426 ENST00000535938.1
SAGE1
sarcoma antigen 1
chrX_+_134975858 0.420 ENST00000537770.1
SAGE1
sarcoma antigen 1
chr17_-_40428359 0.415 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr12_-_15038779 0.394 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr4_-_109089573 0.371 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr6_+_44187242 0.362 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr1_+_100315613 0.359 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr11_-_134123142 0.355 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
THYN1



thymocyte nuclear protein 1



chr16_+_2255841 0.336 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr3_+_14444063 0.323 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6


solute carrier family 6 (neurotransmitter transporter), member 6


chrX_+_46771711 0.319 ENST00000424392.1
ENST00000397189.1
PHF16

jade family PHD finger 3

chr7_+_150264365 0.316 ENST00000255945.2
ENST00000461940.1
GIMAP4

GTPase, IMAP family member 4

chr1_+_95699704 0.302 ENST00000370202.4
RWDD3
RWD domain containing 3
chr1_+_100316041 0.299 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL


amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase


chr1_-_244615425 0.296 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr6_-_35656685 0.287 ENST00000539068.1
ENST00000540787.1
FKBP5

FK506 binding protein 5

chrX_+_46771848 0.276 ENST00000218343.4
PHF16
jade family PHD finger 3
chr7_+_107384579 0.275 ENST00000222597.2
ENST00000415884.2
CBLL1

Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase

chr3_-_58563094 0.274 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr21_-_39870339 0.265 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chr1_+_95699740 0.264 ENST00000429514.2
ENST00000263893.6
RWDD3

RWD domain containing 3

chr1_+_46668994 0.261 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr9_-_35103105 0.259 ENST00000452248.2
ENST00000356493.5
STOML2

stomatin (EPB72)-like 2

chr9_+_132934835 0.256 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr1_-_111991850 0.255 ENST00000411751.2
WDR77
WD repeat domain 77
chr10_-_49701686 0.254 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr6_-_35656712 0.252 ENST00000357266.4
ENST00000542713.1
FKBP5

FK506 binding protein 5

chr1_-_113249948 0.248 ENST00000339083.7
ENST00000369642.3
RHOC

ras homolog family member C

chr1_+_93544791 0.245 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2


metal response element binding transcription factor 2


chr1_+_93544821 0.234 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr14_+_57735614 0.222 ENST00000261558.3
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr2_+_234668894 0.222 ENST00000608383.1
ENST00000360418.3
ENST00000305208.5
UGT1A1

UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8

UDP glucuronosyltransferase 1 family, polypeptide A1
chr7_-_107880508 0.221 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr21_+_45209394 0.220 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr10_+_21823079 0.213 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10


myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10


chr1_-_43833628 0.207 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr11_+_75526212 0.200 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr11_+_64002292 0.198 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr7_-_37026108 0.188 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr19_+_41509851 0.185 ENST00000593831.1
ENST00000330446.5
CYP2B6

cytochrome P450, family 2, subfamily B, polypeptide 6

chr1_-_161087802 0.181 ENST00000368010.3
PFDN2
prefoldin subunit 2
chr1_+_111992064 0.180 ENST00000483994.1
ATP5F1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr11_+_64001962 0.179 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr22_+_22599075 0.173 ENST00000403807.3
VPREB1
pre-B lymphocyte 1
chr7_-_128045984 0.170 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chrX_-_129299638 0.169 ENST00000535724.1
ENST00000346424.2
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chr2_+_46769798 0.166 ENST00000238738.4
RHOQ
ras homolog family member Q
chr6_+_41755389 0.160 ENST00000398884.3
ENST00000398881.3
TOMM6

translocase of outer mitochondrial membrane 6 homolog (yeast)

chr1_-_113249678 0.159 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC



ras homolog family member C



chr8_-_22526597 0.158 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
BIN3



bridging integrator 3



chr17_-_39222131 0.155 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr3_+_49057876 0.153 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr10_+_21823243 0.152 ENST00000307729.7
ENST00000377091.2
MLLT10

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10

chrX_-_129299847 0.148 ENST00000319908.3
ENST00000287295.3
AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

chrX_+_118425471 0.145 ENST00000428222.1
RP5-1139I1.1
RP5-1139I1.1
chr2_+_169926047 0.142 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr19_-_11450249 0.139 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr1_+_16370271 0.128 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb
chr22_+_29702572 0.127 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1


growth arrest-specific 2 like 1


chr1_-_113249734 0.125 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC




ras homolog family member C




chr6_+_31540056 0.122 ENST00000418386.2
LTA
lymphotoxin alpha
chr7_-_135412925 0.117 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chrX_+_13707235 0.116 ENST00000464506.1
RAB9A
RAB9A, member RAS oncogene family
chrX_+_77166172 0.114 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr15_+_85523671 0.114 ENST00000310298.4
ENST00000557957.1
PDE8A

phosphodiesterase 8A

chr1_-_20446020 0.109 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chrX_+_24711997 0.106 ENST00000379068.3
ENST00000379059.3
POLA1

polymerase (DNA directed), alpha 1, catalytic subunit

chr14_+_38677123 0.103 ENST00000267377.2
SSTR1
somatostatin receptor 1
chr11_-_2193025 0.101 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH



tyrosine hydroxylase



chr10_-_81708854 0.100 ENST00000372292.3
SFTPD
surfactant protein D
chr1_-_111991908 0.097 ENST00000235090.5
WDR77
WD repeat domain 77
chr2_-_27938593 0.096 ENST00000379677.2
AC074091.13
Uncharacterized protein
chr19_-_50169064 0.091 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3






interferon regulatory factor 3






chr1_+_161087873 0.089 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1



nitrilase 1



chr17_+_40913210 0.087 ENST00000253796.5
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr19_+_34287751 0.082 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15



potassium channel tetramerization domain containing 15



chr5_-_64920115 0.082 ENST00000381018.3
ENST00000274327.7
TRIM23

tripartite motif containing 23

chr12_-_27091183 0.078 ENST00000544548.1
ENST00000261191.7
ENST00000537336.1
ASUN


asunder spermatogenesis regulator


chr17_+_28804380 0.077 ENST00000225724.5
ENST00000451249.2
ENST00000467337.2
ENST00000581721.1
ENST00000414833.2
GOSR1




golgi SNAP receptor complex member 1




chrX_+_70364667 0.077 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3



neuroligin 3



chr15_+_77712993 0.072 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A


high mobility group 20A


chr19_-_50168962 0.072 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3









interferon regulatory factor 3









chr22_-_24622080 0.070 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chr1_+_16348366 0.069 ENST00000375692.1
ENST00000420078.1
CLCNKA

chloride channel, voltage-sensitive Ka

chr14_-_50999190 0.067 ENST00000557390.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr4_-_66536057 0.066 ENST00000273854.3
EPHA5
EPH receptor A5
chr5_+_64920543 0.065 ENST00000399438.3
ENST00000510585.2
TRAPPC13
CTC-534A2.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr9_-_16870704 0.063 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2



basonuclin 2



chr11_+_63606558 0.063 ENST00000350490.7
ENST00000502399.3
MARK2

MAP/microtubule affinity-regulating kinase 2

chr17_-_39507064 0.063 ENST00000007735.3
KRT33A
keratin 33A
chr4_-_121993673 0.063 ENST00000379692.4
NDNF
neuron-derived neurotrophic factor
chr4_-_66536196 0.060 ENST00000511294.1
EPHA5
EPH receptor A5
chr15_-_71407833 0.058 ENST00000449977.2
CT62
cancer/testis antigen 62
chr19_+_10563567 0.055 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_16348497 0.054 ENST00000439316.2
CLCNKA
chloride channel, voltage-sensitive Ka
chr1_+_1567474 0.049 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr10_+_50818343 0.047 ENST00000374115.3
SLC18A3
solute carrier family 18 (vesicular acetylcholine transporter), member 3
chr19_-_46142680 0.045 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr19_-_42931567 0.042 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr7_+_39017504 0.037 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr22_+_21369316 0.037 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6




purinergic receptor P2X, ligand-gated ion channel, 6




chr11_+_63606477 0.036 ENST00000508192.1
ENST00000361128.5
MARK2

MAP/microtubule affinity-regulating kinase 2

chr17_-_18945798 0.033 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr11_-_22647350 0.033 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chrX_+_18725758 0.032 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1


protein phosphatase, EF-hand calcium binding domain 1


chr6_-_87804815 0.032 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr11_+_15095108 0.030 ENST00000324229.6
ENST00000533448.1
CALCB

calcitonin-related polypeptide beta

chr3_-_45837959 0.030 ENST00000353278.4
ENST00000456124.2
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr14_+_22739823 0.029 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr19_-_46142637 0.028 ENST00000590043.1
ENST00000589876.1
EML2

echinoderm microtubule associated protein like 2

chr10_+_118350468 0.026 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1


pancreatic lipase-related protein 1


chr15_-_71407806 0.026 ENST00000566432.1
ENST00000567117.1
CT62

cancer/testis antigen 62

chr1_+_44870866 0.025 ENST00000355387.2
ENST00000361799.2
RNF220

ring finger protein 220

chr1_+_22962948 0.023 ENST00000374642.3
C1QA
complement component 1, q subcomponent, A chain
chr11_+_63606373 0.022 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr2_-_89399845 0.021 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr22_+_41956767 0.020 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr12_-_11002063 0.016 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4


proline rich 4 (lacrimal)


chr1_+_17559776 0.016 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1


peptidyl arginine deiminase, type I


chrX_+_91034260 0.016 ENST00000395337.2
PCDH11X
protocadherin 11 X-linked
chr10_+_60094735 0.016 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr17_-_39191107 0.015 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr4_+_111397216 0.014 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr6_+_31730773 0.014 ENST00000415669.2
ENST00000425424.1
SAPCD1

suppressor APC domain containing 1

chr11_-_2182388 0.013 ENST00000397270.1
ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
INS-IGF2
INS



INS-IGF2 readthrough
insulin



chr4_+_95917383 0.013 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr2_+_89184868 0.012 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chrX_+_53078273 0.012 ENST00000332582.4
GPR173
G protein-coupled receptor 173
chr2_-_99552620 0.012 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L


KIAA1211-like


chr3_-_45838011 0.011 ENST00000358525.4
ENST00000413781.1
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr4_-_66535653 0.008 ENST00000354839.4
ENST00000432638.2
EPHA5

EPH receptor A5

chr12_-_11036844 0.008 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr17_-_56609302 0.005 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4





septin 4





chr2_+_11679963 0.004 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr2_+_90248739 0.003 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr15_+_80351910 0.001 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.4 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) response to interleukin-15(GO:0070672) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.4 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 0.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439) positive regulation of chronic inflammatory response(GO:0002678) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.4 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.1 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410)
0.0 0.8 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.5 GO:0030146 obsolete diuresis(GO:0030146) regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0 0.4 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0010273 regulation of oxidative phosphorylation(GO:0002082) detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.6 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0006273 DNA replication, synthesis of RNA primer(GO:0006269) lagging strand elongation(GO:0006273)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.5 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.5 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.1 GO:0009187 cyclic nucleotide metabolic process(GO:0009187)
0.0 0.0 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0035326 enhancer binding(GO:0035326)
0.1 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.0 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)