• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: ZKSCAN1

Z-value: 0.772

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_4385230	2.352	ENST00000536537.1	CCND2	cyclin D2
chr11_-_58343319	1.843	ENST00000395074.2	LPXN	leupaxin
chr22_-_37640277	1.225	ENST00000401529.3 ENST00000249071.6	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640456	0.880	ENST00000405484.1 ENST00000441619.1 ENST00000406508.1	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_158345462	0.722	ENST00000439355.1 ENST00000540637.1	CYTIP	cytohesin 1 interacting protein
chr19_-_55660561	0.687	ENST00000587758.1 ENST00000356783.5 ENST00000291901.8 ENST00000588426.1 ENST00000588147.1 ENST00000536926.1 ENST00000588981.1	TNNT1	troponin T type 1 (skeletal, slow)
chr19_+_39138320	0.621	ENST00000424234.2 ENST00000390009.3 ENST00000589528.1	ACTN4	actinin, alpha 4
chr1_+_65613340	0.604	ENST00000546702.1	AK4	adenylate kinase 4
chr20_-_56265680	0.582	ENST00000414037.1	PMEPA1	prostate transmembrane protein, androgen induced 1
chr5_-_134735568	0.481	ENST00000510038.1 ENST00000304332.4	H2AFY	H2A histone family, member Y
chr8_-_131028869	0.477	ENST00000518283.1 ENST00000519110.1	FAM49B	family with sequence similarity 49, member B
chr1_+_46668994	0.466	ENST00000371980.3	LURAP1	leucine rich adaptor protein 1
chrX_+_47441712	0.455	ENST00000218388.4 ENST00000377018.2 ENST00000456754.2 ENST00000377017.1 ENST00000441738.1	TIMP1	TIMP metallopeptidase inhibitor 1
chr9_-_112260531	0.425	ENST00000374541.2 ENST00000262539.3	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr20_+_43343517	0.410	ENST00000372865.4	WISP2	WNT1 inducible signaling pathway protein 2
chr20_+_43343476	0.399	ENST00000372868.2	WISP2	WNT1 inducible signaling pathway protein 2
chr9_+_132934835	0.386	ENST00000372398.3	NCS1	neuronal calcium sensor 1
chr5_-_127873659	0.368	ENST00000262464.4	FBN2	fibrillin 2
chr1_+_65613217	0.359	ENST00000545314.1	AK4	adenylate kinase 4
chr22_+_29702572	0.301	ENST00000407647.2 ENST00000416823.1 ENST00000428622.1	GAS2L1	growth arrest-specific 2 like 1
chr15_-_34635314	0.272	ENST00000557912.1 ENST00000328848.4	NOP10	NOP10 ribonucleoprotein
chr11_+_70049269	0.261	ENST00000301838.4	FADD	Fas (TNFRSF6)-associated via death domain
chr19_+_39138271	0.242	ENST00000252699.2	ACTN4	actinin, alpha 4
chr19_-_3062465	0.240	ENST00000327141.4	AES	amino-terminal enhancer of split
chr5_+_174151536	0.232	ENST00000239243.6 ENST00000507785.1	MSX2	msh homeobox 2
chr22_+_21921994	0.231	ENST00000545681.1	UBE2L3	ubiquitin-conjugating enzyme E2L 3
chr14_+_103851712	0.222	ENST00000440884.3 ENST00000416682.2 ENST00000429436.2 ENST00000303622.9	MARK3	MAP/microtubule affinity-regulating kinase 3
chr11_-_118134997	0.222	ENST00000278937.2	MPZL2	myelin protein zero-like 2
chr1_-_160549235	0.212	ENST00000368054.3 ENST00000368048.3 ENST00000311224.4 ENST00000368051.3 ENST00000534968.1	CD84	CD84 molecule
chr10_+_112679301	0.204	ENST00000265277.5 ENST00000369452.4	SHOC2	soc-2 suppressor of clear homolog (C. elegans)
chr5_+_135394840	0.202	ENST00000503087.1	TGFBI	transforming growth factor, beta-induced, 68kDa
chr16_+_19125252	0.202	ENST00000566735.1 ENST00000381440.3	ITPRIPL2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr19_-_3062881	0.200	ENST00000586742.1	AES	amino-terminal enhancer of split
chr15_-_49103235	0.199	ENST00000380950.2	CEP152	centrosomal protein 152kDa
chr2_+_74120094	0.195	ENST00000409731.3 ENST00000345517.3 ENST00000409918.1 ENST00000442912.1 ENST00000409624.1	ACTG2	actin, gamma 2, smooth muscle, enteric
chr17_-_73150599	0.193	ENST00000392566.2 ENST00000581874.1	HN1	hematological and neurological expressed 1
chr17_+_26800756	0.187	ENST00000537681.1	SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr20_+_44098385	0.185	ENST00000217425.5 ENST00000339946.3	WFDC2	WAP four-disulfide core domain 2
chr20_+_44098346	0.184	ENST00000372676.3	WFDC2	WAP four-disulfide core domain 2
chrX_+_109245863	0.183	ENST00000372072.3	TMEM164	transmembrane protein 164
chr22_+_33197683	0.179	ENST00000266085.6	TIMP3	TIMP metallopeptidase inhibitor 3
chr2_-_183387430	0.175	ENST00000410103.1	PDE1A	phosphodiesterase 1A, calmodulin-dependent
chr2_-_37193606	0.175	ENST00000379213.2 ENST00000263918.4	STRN	striatin, calmodulin binding protein
chr17_+_26800648	0.174	ENST00000545060.1	SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr19_+_10196781	0.172	ENST00000253110.11	C19orf66	chromosome 19 open reading frame 66
chr17_-_26220366	0.167	ENST00000460380.2 ENST00000508862.1 ENST00000379102.3 ENST00000582441.1	LYRM9 RP1-66C13.4	LYR motif containing 9 Uncharacterized protein
chr19_-_3063099	0.163	ENST00000221561.8	AES	amino-terminal enhancer of split
chr1_-_36615051	0.161	ENST00000373163.1	TRAPPC3	trafficking protein particle complex 3
chr6_+_35265586	0.159	ENST00000542066.1 ENST00000316637.5	DEF6	differentially expressed in FDCP 6 homolog (mouse)
chr17_-_73150629	0.153	ENST00000356033.4 ENST00000405458.3 ENST00000409753.3	HN1	hematological and neurological expressed 1
chr1_-_36615065	0.144	ENST00000373166.3 ENST00000373159.1 ENST00000373162.1	TRAPPC3	trafficking protein particle complex 3
chr19_+_13135790	0.133	ENST00000358552.3	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_122326662	0.132	ENST00000261817.2 ENST00000538613.1 ENST00000542602.1	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr5_-_134734901	0.126	ENST00000312469.4 ENST00000423969.2	H2AFY	H2A histone family, member Y
chr15_-_80215984	0.125	ENST00000485386.1 ENST00000479961.1	ST20 ST20-MTHFS	suppressor of tumorigenicity 20 ST20-MTHFS readthrough
chr17_+_27071002	0.120	ENST00000262395.5 ENST00000422344.1 ENST00000444415.3 ENST00000262396.6	TRAF4	TNF receptor-associated factor 4
chr19_-_19051993	0.115	ENST00000594794.1 ENST00000355887.6 ENST00000392351.3 ENST00000596482.1	HOMER3	homer homolog 3 (Drosophila)
chr7_+_87563557	0.113	ENST00000439864.1 ENST00000412441.1 ENST00000398201.4 ENST00000265727.7 ENST00000315984.7 ENST00000398209.3	ADAM22	ADAM metallopeptidase domain 22
chr16_+_2076869	0.113	ENST00000424542.2 ENST00000432365.2	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr6_+_151815143	0.113	ENST00000239374.7 ENST00000367290.5	CCDC170	coiled-coil domain containing 170
chr10_+_102222798	0.112	ENST00000343737.5	WNT8B	wingless-type MMTV integration site family, member 8B
chr11_-_73720276	0.104	ENST00000348534.4	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)
chr12_+_122326630	0.101	ENST00000541212.1 ENST00000340175.5	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr4_-_176733897	0.100	ENST00000393658.2	GPM6A	glycoprotein M6A
chr3_+_53528659	0.096	ENST00000350061.5	CACNA1D	calcium channel, voltage-dependent, L type, alpha 1D subunit
chr2_+_113931513	0.095	ENST00000245796.6 ENST00000441564.3	PSD4	pleckstrin and Sec7 domain containing 4
chr16_+_3550924	0.094	ENST00000576634.1 ENST00000574369.1 ENST00000341633.5 ENST00000417763.2 ENST00000571025.1	CLUAP1	clusterin associated protein 1
chr19_+_18794470	0.087	ENST00000321949.8 ENST00000338797.6	CRTC1	CREB regulated transcription coactivator 1
chr17_+_75372165	0.081	ENST00000427674.2	SEPT9	septin 9
chrX_-_15402498	0.078	ENST00000297904.3	FIGF	c-fos induced growth factor (vascular endothelial growth factor D)
chr10_-_88281494	0.077	ENST00000298767.5	WAPAL	wings apart-like homolog (Drosophila)
chr11_-_73720122	0.077	ENST00000426995.2	UCP3	uncoupling protein 3 (mitochondrial, proton carrier)
chr19_+_13135731	0.071	ENST00000587260.1	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_155224751	0.069	ENST00000350210.2 ENST00000368368.3	FAM189B	family with sequence similarity 189, member B
chr1_+_32083301	0.064	ENST00000403528.2	HCRTR1	hypocretin (orexin) receptor 1
chr2_+_101179152	0.060	ENST00000264254.6	PDCL3	phosducin-like 3
chr7_+_87563458	0.060	ENST00000398204.4	ADAM22	ADAM metallopeptidase domain 22
chr10_-_112678976	0.058	ENST00000448814.1	BBIP1	BBSome interacting protein 1
chr15_+_75494214	0.056	ENST00000394987.4	C15orf39	chromosome 15 open reading frame 39
chr15_-_49103184	0.052	ENST00000399334.3 ENST00000325747.5	CEP152	centrosomal protein 152kDa
chr19_-_15918936	0.048	ENST00000334920.2	OR10H1	olfactory receptor, family 10, subfamily H, member 1
chr2_+_1488435	0.038	ENST00000446278.1 ENST00000469607.1	TPO	thyroid peroxidase
chr17_+_18163848	0.038	ENST00000323019.4 ENST00000578174.1 ENST00000395704.4 ENST00000395703.4 ENST00000578621.1 ENST00000579341.1	MIEF2	mitochondrial elongation factor 2
chr1_-_177134024	0.037	ENST00000367654.3	ASTN1	astrotactin 1
chr10_-_126432619	0.036	ENST00000337318.3	FAM53B	family with sequence similarity 53, member B
chr2_+_27070964	0.035	ENST00000288699.6	DPYSL5	dihydropyrimidinase-like 5
chr18_+_52495426	0.034	ENST00000262094.5	RAB27B	RAB27B, member RAS oncogene family
chr19_+_3178736	0.033	ENST00000246115.3	S1PR4	sphingosine-1-phosphate receptor 4
chr19_+_51630287	0.032	ENST00000599948.1	SIGLEC9	sialic acid binding Ig-like lectin 9
chr6_+_32944119	0.031	ENST00000606059.1	BRD2	bromodomain containing 2
chr11_+_72975578	0.030	ENST00000393592.2	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr10_-_112678904	0.028	ENST00000423273.1 ENST00000436562.1 ENST00000447005.1 ENST00000454061.1	BBIP1	BBSome interacting protein 1
chr11_+_72975524	0.026	ENST00000540342.1 ENST00000542092.1	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr20_-_3644046	0.021	ENST00000290417.2 ENST00000319242.3	GFRA4	GDNF family receptor alpha 4
chr4_+_39460689	0.020	ENST00000381846.1	LIAS	lipoic acid synthetase
chr3_+_184081213	0.019	ENST00000429568.1	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr11_+_72975559	0.017	ENST00000349767.2	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_-_30640811	0.012	ENST00000376442.3	DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr3_+_184081175	0.012	ENST00000452961.1 ENST00000296223.3	POLR2H	polymerase (RNA) II (DNA directed) polypeptide H
chr3_-_195310802	0.008	ENST00000421243.1 ENST00000453131.1	APOD	apolipoprotein D
chr1_-_51796987	0.006	ENST00000262676.5	TTC39A	tetratricopeptide repeat domain 39A
chr1_+_209859510	0.005	ENST00000367028.2 ENST00000261465.1	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chr19_+_850985	0.001	ENST00000590230.1	ELANE	elastase, neutrophil expressed
chr3_+_63898275	0.001	ENST00000538065.1	ATXN7	ataxin 7

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.3	0.9	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.2	1.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	2.4	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1	0.6	GO:0007549	dosage compensation(GO:0007549)
0.1	0.7	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	0.2	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.2	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.1	0.1	GO:0043049	otic placode formation(GO:0043049)
0.1	0.4	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.4	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.3	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.3	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.6	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0001740	Barr body(GO:0001740)
0.1	2.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	0.9	GO:0031143	pseudopodium(GO:0031143)
0.1	0.2	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.7	GO:0005861	troponin complex(GO:0005861)
0.0	0.4	GO:0001527	microfibril(GO:0001527)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0015361	low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1	1.0	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.2	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
0.0	0.7	GO:0031014	troponin T binding(GO:0031014)
0.0	0.6	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.2	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	1.2	GO:0005178	integrin binding(GO:0005178)

---