• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: ZNF282

Z-value: 0.582

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_169753156	0.894	ENST00000393726.3 ENST00000507735.1	PALLD	palladin, cytoskeletal associated protein
chr6_+_106959718	0.812	ENST00000369066.3	AIM1	absent in melanoma 1
chrX_-_13835147	0.584	ENST00000493677.1 ENST00000355135.2	GPM6B	glycoprotein M6B
chr17_+_42422662	0.516	ENST00000593167.1 ENST00000585512.1 ENST00000591740.1 ENST00000592783.1 ENST00000587387.1 ENST00000588237.1 ENST00000589265.1	GRN	granulin
chr17_+_42422637	0.507	ENST00000053867.3 ENST00000588143.1	GRN	granulin
chr20_+_18269121	0.456	ENST00000377671.3 ENST00000360010.5 ENST00000396026.3 ENST00000402618.2 ENST00000401790.1 ENST00000434018.1 ENST00000538547.1 ENST00000535822.1	ZNF133	zinc finger protein 133
chr22_+_45898712	0.438	ENST00000455233.1 ENST00000348697.2 ENST00000402984.3 ENST00000262722.7 ENST00000327858.6 ENST00000442170.2 ENST00000340923.5 ENST00000439835.1	FBLN1	fibulin 1
chr6_+_129204337	0.435	ENST00000421865.2	LAMA2	laminin, alpha 2
chr12_-_122296755	0.405	ENST00000289004.4	HPD	4-hydroxyphenylpyruvate dioxygenase
chr17_+_7942335	0.368	ENST00000380183.4 ENST00000572022.1 ENST00000380173.2	ALOX15B	arachidonate 15-lipoxygenase, type B
chr14_+_55590646	0.333	ENST00000553493.1	LGALS3	lectin, galactoside-binding, soluble, 3
chr10_+_114135004	0.316	ENST00000393081.1	ACSL5	acyl-CoA synthetase long-chain family member 5
chr1_+_2004901	0.300	ENST00000400921.2	PRKCZ	protein kinase C, zeta
chrX_-_13835461	0.297	ENST00000316715.4 ENST00000356942.5	GPM6B	glycoprotein M6B
chr21_+_35747773	0.287	ENST00000399292.3 ENST00000399299.1 ENST00000399295.2	SMIM11	small integral membrane protein 11
chr17_+_66509019	0.274	ENST00000585981.1 ENST00000589480.1 ENST00000585815.1	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha
chr2_+_219283815	0.243	ENST00000248444.5 ENST00000454069.1 ENST00000392114.2	VIL1	villin 1
chr1_+_35247859	0.224	ENST00000373362.3	GJB3	gap junction protein, beta 3, 31kDa
chr8_-_23261589	0.222	ENST00000524168.1 ENST00000523833.2 ENST00000519243.1 ENST00000389131.3	LOXL2	lysyl oxidase-like 2
chr4_-_153457197	0.221	ENST00000281708.4	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr16_+_67204400	0.220	ENST00000563439.1 ENST00000432069.2 ENST00000564992.1 ENST00000564053.1	NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)
chr13_+_31309645	0.220	ENST00000380490.3	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr11_+_66278080	0.216	ENST00000318312.7 ENST00000526815.1 ENST00000537537.1 ENST00000525809.1 ENST00000455748.2 ENST00000393994.2	BBS1	Bardet-Biedl syndrome 1
chr2_+_242289502	0.214	ENST00000451310.1	SEPT2	septin 2
chr19_-_39390440	0.207	ENST00000249396.7 ENST00000414941.1 ENST00000392081.2	SIRT2	sirtuin 2
chr9_+_126777676	0.204	ENST00000488674.2	LHX2	LIM homeobox 2
chr1_+_2005425	0.200	ENST00000461106.2	PRKCZ	protein kinase C, zeta
chr20_-_43150601	0.198	ENST00000541235.1 ENST00000255175.1 ENST00000342374.4	SERINC3	serine incorporator 3
chr1_-_9129735	0.194	ENST00000377424.4	SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr5_+_78365577	0.182	ENST00000518666.1 ENST00000521567.1	BHMT2	betaine--homocysteine S-methyltransferase 2
chr1_-_24151892	0.178	ENST00000235958.4	HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_+_13910479	0.173	ENST00000509009.1	PDPN	podoplanin
chr1_+_145507587	0.172	ENST00000330165.8 ENST00000369307.3	RBM8A	RNA binding motif protein 8A
chr1_-_24151903	0.171	ENST00000436439.2 ENST00000374490.3	HMGCL	3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_+_151171012	0.164	ENST00000349792.5 ENST00000409426.1 ENST00000441902.2 ENST00000368890.4 ENST00000424999.1 ENST00000368888.4	PIP5K1A	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr19_-_39390350	0.160	ENST00000447739.1 ENST00000358931.5 ENST00000407552.1	SIRT2	sirtuin 2
chr1_-_13390765	0.153	ENST00000357367.2	PRAMEF8	PRAME family member 8
chr3_-_106959424	0.151	ENST00000607801.1 ENST00000479612.2 ENST00000484698.1 ENST00000477210.2 ENST00000473636.1	LINC00882	long intergenic non-protein coding RNA 882
chr1_+_160313062	0.149	ENST00000294785.5 ENST00000368063.1 ENST00000437169.1	NCSTN	nicastrin
chr12_-_46766577	0.147	ENST00000256689.5	SLC38A2	solute carrier family 38, member 2
chr1_+_13910757	0.137	ENST00000376061.4 ENST00000513143.1	PDPN	podoplanin
chr5_+_175299743	0.125	ENST00000502265.1	CPLX2	complexin 2
chr16_+_67927147	0.121	ENST00000291041.5	PSKH1	protein serine kinase H1
chr16_-_70239683	0.116	ENST00000601706.1	AC009060.1	Uncharacterized protein
chr17_-_77924627	0.110	ENST00000572862.1 ENST00000573782.1 ENST00000574427.1 ENST00000570373.1 ENST00000340848.7 ENST00000576768.1	TBC1D16	TBC1 domain family, member 16
chr5_+_167718604	0.110	ENST00000265293.4	WWC1	WW and C2 domain containing 1
chr10_+_95753714	0.108	ENST00000260766.3	PLCE1	phospholipase C, epsilon 1
chr19_-_58220517	0.107	ENST00000512439.2 ENST00000426889.1	ZNF154	zinc finger protein 154
chr1_-_9129631	0.106	ENST00000377414.3	SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr2_-_9695847	0.101	ENST00000310823.3 ENST00000497134.1	ADAM17	ADAM metallopeptidase domain 17
chr6_+_39760783	0.100	ENST00000398904.2 ENST00000538976.1	DAAM2	dishevelled associated activator of morphogenesis 2
chr7_+_139025875	0.092	ENST00000297534.6	C7orf55	chromosome 7 open reading frame 55
chr18_+_54318566	0.089	ENST00000589935.1 ENST00000357574.3	WDR7	WD repeat domain 7
chr1_+_17248418	0.086	ENST00000375541.5	CROCC	ciliary rootlet coiled-coil, rootletin
chr19_+_44617511	0.084	ENST00000262894.6 ENST00000588926.1 ENST00000592780.1	ZNF225	zinc finger protein 225
chr12_-_9102549	0.082	ENST00000000412.3	M6PR	mannose-6-phosphate receptor (cation dependent)
chr15_+_51200871	0.081	ENST00000560508.1	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit
chr7_+_16828866	0.078	ENST00000597084.1	AC073333.1	Uncharacterized protein
chr5_-_175788758	0.077	ENST00000510164.1 ENST00000533553.1 ENST00000504688.1 ENST00000393725.2 ENST00000503082.1 ENST00000506983.1	KIAA1191	KIAA1191
chr5_+_140552218	0.062	ENST00000231137.3	PCDHB7	protocadherin beta 7
chr17_+_41323204	0.062	ENST00000542611.1 ENST00000590996.1 ENST00000389312.4 ENST00000589872.1	NBR1	neighbor of BRCA1 gene 1
chr15_-_44955842	0.062	ENST00000427534.2 ENST00000559193.1 ENST00000261866.7 ENST00000535302.2 ENST00000558319.1	SPG11	spastic paraplegia 11 (autosomal recessive)
chr17_-_56605341	0.059	ENST00000583114.1	SEPT4	septin 4
chr19_+_7953384	0.058	ENST00000306708.6	LRRC8E	leucine rich repeat containing 8 family, member E
chr2_+_233415363	0.058	ENST00000409514.1 ENST00000409098.1 ENST00000409495.1 ENST00000409167.3 ENST00000409322.1 ENST00000409394.1	EIF4E2	eukaryotic translation initiation factor 4E family member 2
chr12_-_13248562	0.054	ENST00000457134.2 ENST00000537302.1	GSG1	germ cell associated 1
chr6_+_32938665	0.053	ENST00000374831.4 ENST00000395289.2	BRD2	bromodomain containing 2
chr18_-_54318353	0.048	ENST00000590954.1 ENST00000540155.1	TXNL1	thioredoxin-like 1
chr9_+_34652164	0.044	ENST00000441545.2 ENST00000553620.1	IL11RA	interleukin 11 receptor, alpha
chr17_+_44039704	0.044	ENST00000420682.2 ENST00000415613.2 ENST00000571987.1 ENST00000574436.1 ENST00000431008.3	MAPT	microtubule-associated protein tau
chr1_-_155947951	0.041	ENST00000313695.7 ENST00000497907.1	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_+_45927994	0.038	ENST00000357632.2 ENST00000395963.2	CCR9	chemokine (C-C motif) receptor 9
chr6_-_79944336	0.037	ENST00000344726.5 ENST00000275036.7	HMGN3	high mobility group nucleosomal binding domain 3
chr14_-_24911448	0.037	ENST00000555355.1 ENST00000553343.1 ENST00000556523.1 ENST00000556249.1 ENST00000538105.2 ENST00000555225.1	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1
chr15_+_51200859	0.037	ENST00000261842.5	AP4E1	adaptor-related protein complex 4, epsilon 1 subunit
chr1_+_52682052	0.033	ENST00000371591.1	ZFYVE9	zinc finger, FYVE domain containing 9
chr12_-_49582978	0.029	ENST00000301071.7	TUBA1A	tubulin, alpha 1a
chr12_-_13248598	0.029	ENST00000337630.6 ENST00000545699.1	GSG1	germ cell associated 1
chr19_-_46285736	0.028	ENST00000291270.4 ENST00000447742.2 ENST00000354227.5	DMPK	dystrophia myotonica-protein kinase
chr11_-_66445219	0.028	ENST00000525754.1 ENST00000531969.1 ENST00000524637.1 ENST00000531036.2 ENST00000310046.4	RBM4B	RNA binding motif protein 4B
chr16_+_30207122	0.028	ENST00000395137.2	SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr8_-_27630102	0.024	ENST00000356537.4 ENST00000522915.1 ENST00000539095.1	CCDC25	coiled-coil domain containing 25
chr19_-_51340469	0.023	ENST00000326856.4	KLK15	kallikrein-related peptidase 15
chr16_+_29467780	0.020	ENST00000395400.3	SULT1A4	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr11_-_6633799	0.013	ENST00000299424.4	TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr20_-_2451395	0.013	ENST00000339610.6 ENST00000381342.2 ENST00000438552.2	SNRPB	small nuclear ribonucleoprotein polypeptides B and B1
chr5_+_65892174	0.012	ENST00000404260.3 ENST00000403625.2 ENST00000406374.1	MAST4	microtubule associated serine/threonine kinase family member 4
chr19_+_39390587	0.010	ENST00000572515.1 ENST00000392079.3 ENST00000575359.1 ENST00000313582.5	NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_-_68479614	0.004	ENST00000234310.3	PPP3R1	protein phosphatase 3, regulatory subunit B, alpha
chr19_-_6110474	0.003	ENST00000587181.1 ENST00000587321.1 ENST00000586806.1 ENST00000589742.1 ENST00000592546.1 ENST00000303657.5	RFX2	regulatory factor X, 2 (influences HLA class II expression)
chr18_+_54318616	0.003	ENST00000254442.3	WDR7	WD repeat domain 7
chr17_-_73389854	0.002	ENST00000578961.1 ENST00000392564.1 ENST00000582582.1	GRB2	growth factor receptor-bound protein 2
chr2_+_233415488	0.001	ENST00000454501.1	EIF4E2	eukaryotic translation initiation factor 4E family member 2
chr6_+_32938692	0.000	ENST00000443797.2	BRD2	bromodomain containing 2
chr6_+_144471643	0.000	ENST00000367568.4	STX11	syntaxin 11

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.1	0.3	GO:1903961	positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) positive regulation of anion transmembrane transport(GO:1903961)
0.1	0.3	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.1	0.4	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.2	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.1	0.4	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.3	GO:0015755	fructose transport(GO:0015755)
0.0	0.1	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.2	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.3	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.5	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.2	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.3	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.4	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.4	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.3	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.9	GO:0005884	actin filament(GO:0005884)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
0.1	0.4	GO:0042903	tubulin deacetylase activity(GO:0042903)
0.1	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.2	GO:0047150	betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1	0.3	GO:0019863	IgE binding(GO:0019863)
0.0	0.3	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.0	0.3	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.2	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.5	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)

---