Motif ID: ZNF691

Z-value: 0.584


Transcription factors associated with ZNF691:

Gene SymbolEntrez IDGene Name
ZNF691 ENSG00000164011.13 ZNF691



Activity profile for motif ZNF691.

activity profile for motif ZNF691


Sorted Z-values histogram for motif ZNF691

Sorted Z-values for motif ZNF691



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF691

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_23264766 1.583 ENST00000390331.2
 IGLC7
immunoglobulin lambda constant 7
chr11_+_60223312 1.057 ENST00000532491.1
ENST00000532073.1
ENST00000534668.1
ENST00000528313.1
ENST00000533306.1
 MS4A1




membrane-spanning 4-domains, subfamily A, member 1




chr11_+_60223225 1.055 ENST00000524807.1
ENST00000345732.4
 MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr1_+_26644441 0.960 ENST00000374213.2
 CD52
CD52 molecule
chr10_-_91011548 0.716 ENST00000456827.1
 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr11_+_102188272 0.698 ENST00000532808.1
 BIRC3
baculoviral IAP repeat containing 3
chr11_+_121461097 0.597 ENST00000527934.1
 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_+_28199047 0.594 ENST00000373925.1
ENST00000328928.7
ENST00000373927.3
ENST00000427466.1
ENST00000442118.1
ENST00000373921.3
 THEMIS2





thymocyte selection associated family member 2





chr12_-_51717875 0.548 ENST00000604560.1
 BIN2
bridging integrator 2
chr2_-_110371412 0.540 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
 SEPT10





septin 10





chr12_-_51717948 0.460 ENST00000267012.4
 BIN2
bridging integrator 2
chr12_-_51717922 0.452 ENST00000452142.2
 BIN2
bridging integrator 2
chr1_+_26856236 0.442 ENST00000374168.2
ENST00000374166.4
 RPS6KA1

ribosomal protein S6 kinase, 90kDa, polypeptide 1

chr14_-_106725723 0.415 ENST00000390609.2
 IGHV3-23
immunoglobulin heavy variable 3-23
chr8_+_27168988 0.406 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
 PTK2B


protein tyrosine kinase 2 beta


chr2_-_110371720 0.402 ENST00000356688.4
 SEPT10
septin 10
chr2_-_110371664 0.390 ENST00000545389.1
ENST00000423520.1
 SEPT10

septin 10

chr8_-_87526561 0.382 ENST00000523911.1
 RMDN1
regulator of microtubule dynamics 1
chr4_-_120243545 0.350 ENST00000274024.3
 FABP2
fatty acid binding protein 2, intestinal
chr19_-_51472222 0.281 ENST00000376851.3
 KLK6
kallikrein-related peptidase 6
chr17_-_61777459 0.277 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
 LIMD2


LIM domain containing 2


chr17_-_41738931 0.268 ENST00000329168.3
ENST00000549132.1
 MEOX1

mesenchyme homeobox 1

chr6_-_159240415 0.250 ENST00000367075.3
 EZR
ezrin
chr1_+_203734296 0.210 ENST00000442561.2
ENST00000367217.5
 LAX1

lymphocyte transmembrane adaptor 1

chr3_+_44596679 0.198 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
 ZKSCAN7



zinc finger with KRAB and SCAN domains 7



chr1_+_15986364 0.170 ENST00000345034.1
 RSC1A1
regulatory solute carrier protein, family 1, member 1
chr3_-_167452298 0.169 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
 PDCD10


programmed cell death 10


chr9_+_135754263 0.166 ENST00000356311.5
ENST00000350499.6
 C9orf9

chromosome 9 open reading frame 9

chr6_-_144329531 0.164 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
 PLAGL1



pleiomorphic adenoma gene-like 1



chr3_-_167452614 0.157 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
 PDCD10




programmed cell death 10




chr19_-_51472031 0.155 ENST00000391808.1
 KLK6
kallikrein-related peptidase 6
chr1_+_145516560 0.152 ENST00000537888.1
 PEX11B
peroxisomal biogenesis factor 11 beta
chr19_+_50380917 0.147 ENST00000535102.2
 TBC1D17
TBC1 domain family, member 17
chr12_-_51718436 0.136 ENST00000544402.1
 BIN2
bridging integrator 2
chr1_-_203144941 0.120 ENST00000255416.4
 MYBPH
myosin binding protein H
chr3_-_167452262 0.118 ENST00000487947.2
 PDCD10
programmed cell death 10
chr12_+_120502441 0.118 ENST00000446727.2
 CCDC64
coiled-coil domain containing 64
chr11_-_133826852 0.115 ENST00000533871.2
ENST00000321016.8
 IGSF9B

immunoglobulin superfamily, member 9B

chr15_-_74726283 0.110 ENST00000543145.2
 SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr1_+_154966058 0.106 ENST00000392487.1
 LENEP
lens epithelial protein
chr19_-_17932314 0.104 ENST00000598577.1
ENST00000317306.7
ENST00000379695.5
 INSL3


insulin-like 3 (Leydig cell)


chr19_-_50311896 0.103 ENST00000529634.2
 FUZ
fuzzy planar cell polarity protein
chr16_-_1821496 0.093 ENST00000564628.1
ENST00000563498.1
 NME3

NME/NM23 nucleoside diphosphate kinase 3

chr19_-_5903714 0.092 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
 FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr11_-_65655906 0.079 ENST00000533045.1
ENST00000338369.2
ENST00000357519.4
 FIBP


fibroblast growth factor (acidic) intracellular binding protein


chr13_-_52027134 0.078 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
 INTS6




integrator complex subunit 6




chr19_+_50084561 0.077 ENST00000246794.5
 PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr8_+_32579341 0.074 ENST00000519240.1
ENST00000539990.1
 NRG1

neuregulin 1

chr7_-_143059780 0.067 ENST00000409578.1
ENST00000409346.1
 FAM131B

family with sequence similarity 131, member B

chr2_+_238475217 0.064 ENST00000165524.1
 PRLH
prolactin releasing hormone
chr9_+_37486005 0.064 ENST00000377792.3
 POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr17_+_30771279 0.058 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
 PSMD11



proteasome (prosome, macropain) 26S subunit, non-ATPase, 11



chr9_+_37485932 0.056 ENST00000377798.4
ENST00000442009.2
 POLR1E

polymerase (RNA) I polypeptide E, 53kDa

chr4_+_657485 0.055 ENST00000471824.2
 PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr1_-_203055129 0.055 ENST00000241651.4
 MYOG
myogenin (myogenic factor 4)
chr8_-_144679532 0.054 ENST00000534380.1
ENST00000533494.1
ENST00000531218.1
ENST00000526340.1
ENST00000533204.1
ENST00000532400.1
ENST00000529516.1
ENST00000534377.1
ENST00000531621.1
ENST00000530191.1
ENST00000524900.1
ENST00000526838.1
ENST00000531931.1
ENST00000534475.1
ENST00000442189.2
ENST00000524624.1
ENST00000532596.1
ENST00000529832.1
ENST00000530306.1
ENST00000530545.1
ENST00000525261.1
ENST00000534804.1
ENST00000528303.1
ENST00000528610.1
 EEF1D























eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)























chr3_+_129693523 0.053 ENST00000507066.1
 TRH
thyrotropin-releasing hormone
chr11_-_36619771 0.052 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
 RAG2


recombination activating gene 2


chr21_-_37852359 0.052 ENST00000399137.1
ENST00000399135.1
 CLDN14

claudin 14

chr6_+_31553978 0.047 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
 LST1


leukocyte specific transcript 1


chr20_-_1317555 0.047 ENST00000537552.1
 AL136531.1
HCG2043693; Uncharacterized protein
chr5_-_131347501 0.044 ENST00000543479.1
 ACSL6
acyl-CoA synthetase long-chain family member 6
chr2_-_203736334 0.041 ENST00000392237.2
ENST00000416760.1
ENST00000412210.1
 ICA1L


islet cell autoantigen 1,69kDa-like


chr2_+_68961905 0.041 ENST00000295381.3
 ARHGAP25
Rho GTPase activating protein 25
chr11_+_64949899 0.040 ENST00000531068.1
ENST00000527699.1
ENST00000533909.1
ENST00000527323.1
 CAPN1



calpain 1, (mu/I) large subunit



chr6_+_31553901 0.040 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
 LST1



leukocyte specific transcript 1



chr5_-_179045199 0.040 ENST00000523921.1
 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr12_-_12491608 0.039 ENST00000545735.1
 MANSC1
MANSC domain containing 1
chr18_+_11751493 0.038 ENST00000269162.5
 GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr2_+_68961934 0.037 ENST00000409202.3
 ARHGAP25
Rho GTPase activating protein 25
chr13_-_52703187 0.036 ENST00000355568.4
 NEK5
NIMA-related kinase 5
chr19_-_9649253 0.035 ENST00000593003.1
 ZNF426
zinc finger protein 426
chr16_+_810728 0.032 ENST00000563941.1
ENST00000545450.2
ENST00000566549.1
 MSLN


mesothelin


chr19_-_9649303 0.028 ENST00000253115.2
 ZNF426
zinc finger protein 426
chr1_-_16763911 0.028 ENST00000375577.1
ENST00000335496.1
 SPATA21

spermatogenesis associated 21

chr3_+_37493610 0.026 ENST00000264741.5
 ITGA9
integrin, alpha 9
chr1_-_155232221 0.026 ENST00000355379.3
 SCAMP3
secretory carrier membrane protein 3
chr11_-_57148619 0.021 ENST00000287143.2
 PRG3
proteoglycan 3
chr3_-_10452359 0.020 ENST00000452124.1
 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_-_132939317 0.020 ENST00000275191.2
 TAAR2
trace amine associated receptor 2
chr11_+_33902189 0.019 ENST00000330381.2
 AC132216.1
HCG1785179; PRO1787; Uncharacterized protein
chr16_+_23765948 0.018 ENST00000300113.2
 CHP2
calcineurin-like EF-hand protein 2
chr22_-_43539346 0.017 ENST00000327555.5
ENST00000290429.6
 MCAT

malonyl CoA:ACP acyltransferase (mitochondrial)

chr5_+_7396141 0.016 ENST00000338316.4
 ADCY2
adenylate cyclase 2 (brain)
chr1_-_33647267 0.014 ENST00000291416.5
 TRIM62
tripartite motif containing 62
chr6_+_28493666 0.012 ENST00000412168.2
 GPX5
glutathione peroxidase 5 (epididymal androgen-related protein)
chr17_+_79495397 0.010 ENST00000417245.2
ENST00000334850.7
 FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chr11_-_64889529 0.009 ENST00000531743.1
ENST00000527548.1
ENST00000526555.1
ENST00000279259.3
 FAU



Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed



chr4_+_96761238 0.008 ENST00000295266.4
 PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2
chr8_-_144679296 0.006 ENST00000317198.6
 EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr1_-_148202536 0.005 ENST00000544708.1
 PPIAL4D
peptidylprolyl isomerase A (cyclophilin A)-like 4D
chr4_-_7105056 0.003 ENST00000504402.1
ENST00000499242.2
ENST00000501888.2
 RP11-367J11.3


RP11-367J11.3


chr16_+_78133293 0.003 ENST00000566780.1
 WWOX
WW domain containing oxidoreductase
chr2_-_85895295 0.002 ENST00000428225.1
ENST00000519937.2
 SFTPB

surfactant protein B

chr9_+_131447342 0.001 ENST00000409104.3
 SET
SET nuclear oncogene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.3 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 1.0 GO:0045730 respiratory burst(GO:0045730)
0.0 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.5 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 2.4 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 2.2 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.4 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 1.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.6 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.