Motif ID: ZNF740_ZNF219
Z-value: 2.488
Transcription factors associated with ZNF740_ZNF219:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ZNF219 | ENSG00000165804.11 | ZNF219 |
ZNF740 | ENSG00000139651.9 | ZNF740 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.2 | GO:0035408 | histone H3-T6 phosphorylation(GO:0035408) |
1.6 | 4.7 | GO:0010586 | miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587) |
1.2 | 7.3 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.8 | 2.3 | GO:0046015 | carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015) positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
0.5 | 1.4 | GO:0060120 | auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120) |
0.5 | 1.4 | GO:0034139 | regulation of toll-like receptor 3 signaling pathway(GO:0034139) |
0.4 | 1.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.4 | 2.9 | GO:0051571 | positive regulation of histone H3-K4 methylation(GO:0051571) |
0.4 | 2.2 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
0.4 | 2.6 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.3 | 2.8 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.3 | 2.8 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.3 | 0.9 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.3 | 1.2 | GO:0021759 | globus pallidus development(GO:0021759) menarche(GO:0042696) |
0.3 | 0.6 | GO:0060574 | intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576) |
0.3 | 0.8 | GO:0019056 | modulation by virus of host transcription(GO:0019056) regulation of sprouting of injured axon(GO:0048686) positive regulation of sprouting of injured axon(GO:0048687) regulation of axon extension involved in regeneration(GO:0048690) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026) |
0.3 | 2.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
0.3 | 1.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.3 | 1.6 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
0.3 | 0.8 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) protein hexamerization(GO:0034214) |
0.3 | 1.3 | GO:0045767 | obsolete regulation of anti-apoptosis(GO:0045767) |
0.3 | 1.5 | GO:0021877 | forebrain neuron fate commitment(GO:0021877) |
0.2 | 0.5 | GO:0061140 | lung secretory cell differentiation(GO:0061140) |
0.2 | 1.7 | GO:0060033 | anatomical structure regression(GO:0060033) |
0.2 | 0.7 | GO:0001779 | natural killer cell differentiation(GO:0001779) |
0.2 | 1.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.2 | 1.7 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
0.2 | 0.9 | GO:0033602 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of dopamine secretion(GO:0033602) |
0.2 | 1.8 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
0.2 | 1.4 | GO:0033160 | positive regulation of protein import into nucleus, translocation(GO:0033160) |
0.2 | 0.6 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
0.2 | 0.6 | GO:0021919 | BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919) |
0.2 | 1.3 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.2 | 0.7 | GO:0048935 | peripheral nervous system neuron development(GO:0048935) |
0.2 | 0.9 | GO:0017055 | negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055) |
0.2 | 1.6 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.2 | 7.1 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.2 | 1.7 | GO:0001866 | NK T cell proliferation(GO:0001866) |
0.2 | 0.5 | GO:0042501 | serine phosphorylation of STAT protein(GO:0042501) |
0.2 | 0.7 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.2 | 1.7 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.2 | 0.5 | GO:0060316 | positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
0.1 | 1.4 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 0.7 | GO:0001302 | replicative cell aging(GO:0001302) female genitalia morphogenesis(GO:0048807) |
0.1 | 0.3 | GO:0007418 | ventral midline development(GO:0007418) |
0.1 | 0.5 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
0.1 | 0.3 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.1 | 1.0 | GO:0051294 | establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294) |
0.1 | 0.3 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.1 | 1.2 | GO:0016180 | snRNA processing(GO:0016180) |
0.1 | 1.4 | GO:0032876 | regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023) |
0.1 | 0.7 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.1 | 0.7 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.1 | 0.8 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
0.1 | 0.3 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.1 | 0.5 | GO:0032959 | inositol trisphosphate biosynthetic process(GO:0032959) positive regulation of penile erection(GO:0060406) |
0.1 | 0.7 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.1 | 0.5 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
0.1 | 0.5 | GO:0060684 | epithelial-mesenchymal cell signaling(GO:0060684) |
0.1 | 1.6 | GO:0071451 | removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748) |
0.1 | 0.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337) |
0.1 | 0.5 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
0.1 | 0.7 | GO:0015705 | iodide transport(GO:0015705) |
0.1 | 0.4 | GO:0045945 | positive regulation of transcription from RNA polymerase III promoter(GO:0045945) |
0.1 | 0.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
0.1 | 0.3 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
0.1 | 0.7 | GO:0002052 | positive regulation of neuroblast proliferation(GO:0002052) |
0.1 | 0.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.1 | 0.3 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
0.1 | 0.4 | GO:0010832 | negative regulation of myotube differentiation(GO:0010832) |
0.1 | 0.2 | GO:0032714 | negative regulation of interleukin-5 production(GO:0032714) |
0.1 | 1.2 | GO:0060736 | prostate gland growth(GO:0060736) |
0.1 | 1.0 | GO:0002076 | osteoblast development(GO:0002076) |
0.1 | 1.3 | GO:0000380 | alternative mRNA splicing, via spliceosome(GO:0000380) |
0.1 | 0.1 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
0.1 | 0.4 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) cellular response to zinc ion(GO:0071294) |
0.1 | 0.4 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
0.1 | 0.1 | GO:0071635 | negative regulation of transforming growth factor beta production(GO:0071635) |
0.1 | 0.6 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
0.1 | 0.6 | GO:0043545 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
0.1 | 0.3 | GO:0048295 | positive regulation of isotype switching to IgE isotypes(GO:0048295) |
0.1 | 0.3 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
0.1 | 0.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
0.1 | 0.3 | GO:0045299 | otolith mineralization(GO:0045299) |
0.1 | 0.3 | GO:0060999 | positive regulation of dendritic spine development(GO:0060999) positive regulation of dendritic spine morphogenesis(GO:0061003) |
0.1 | 0.8 | GO:0030889 | negative regulation of B cell proliferation(GO:0030889) |
0.1 | 0.6 | GO:0009404 | toxin metabolic process(GO:0009404) |
0.1 | 0.5 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.1 | 0.6 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
0.1 | 0.4 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
0.1 | 0.4 | GO:0002092 | positive regulation of receptor internalization(GO:0002092) |
0.1 | 0.8 | GO:0090399 | replicative senescence(GO:0090399) |
0.1 | 0.1 | GO:0007538 | primary sex determination(GO:0007538) |
0.1 | 0.6 | GO:0016310 | phosphorylation(GO:0016310) |
0.1 | 0.2 | GO:0090281 | negative regulation of calcium ion import(GO:0090281) |
0.1 | 0.5 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
0.1 | 0.4 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
0.1 | 0.3 | GO:0045601 | regulation of endothelial cell differentiation(GO:0045601) |
0.1 | 4.9 | GO:0034339 | obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339) |
0.1 | 0.2 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
0.1 | 0.5 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
0.1 | 0.7 | GO:0051319 | mitotic G2 phase(GO:0000085) G2 phase(GO:0051319) |
0.1 | 0.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
0.1 | 0.2 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
0.1 | 1.4 | GO:1902583 | multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583) |
0.1 | 0.5 | GO:1900087 | traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808) |
0.0 | 0.0 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
0.0 | 0.1 | GO:0060664 | epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664) |
0.0 | 1.7 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
0.0 | 0.4 | GO:0010452 | histone H3-K36 methylation(GO:0010452) |
0.0 | 0.8 | GO:1904031 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
0.0 | 1.0 | GO:0006929 | substrate-dependent cell migration(GO:0006929) |
0.0 | 0.5 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
0.0 | 0.3 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 1.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
0.0 | 0.5 | GO:0051103 | DNA ligation involved in DNA repair(GO:0051103) |
0.0 | 0.2 | GO:0032776 | DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116) |
0.0 | 0.6 | GO:0001893 | maternal placenta development(GO:0001893) |
0.0 | 0.3 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
0.0 | 0.6 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
0.0 | 0.9 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 1.4 | GO:0016571 | histone methylation(GO:0016571) |
0.0 | 5.0 | GO:0006333 | chromatin assembly or disassembly(GO:0006333) |
0.0 | 1.3 | GO:0006338 | chromatin remodeling(GO:0006338) |
0.0 | 0.3 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.8 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
0.0 | 0.1 | GO:0021571 | rhombomere 4 development(GO:0021570) rhombomere 5 development(GO:0021571) facial nucleus development(GO:0021754) |
0.0 | 1.1 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
0.0 | 0.1 | GO:0031960 | response to corticosteroid(GO:0031960) response to glucocorticoid(GO:0051384) |
0.0 | 1.0 | GO:0018208 | peptidyl-proline modification(GO:0018208) |
0.0 | 0.5 | GO:0006376 | mRNA splice site selection(GO:0006376) |
0.0 | 0.3 | GO:0010765 | positive regulation of sodium ion transport(GO:0010765) |
0.0 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.0 | 0.5 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
0.0 | 0.6 | GO:0007520 | myoblast fusion(GO:0007520) |
0.0 | 0.4 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
0.0 | 0.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.3 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.0 | 0.1 | GO:0033147 | negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.1 | GO:0021615 | glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.1 | GO:0042474 | middle ear morphogenesis(GO:0042474) |
0.0 | 0.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.2 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.0 | 0.2 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.4 | GO:0009220 | pyrimidine ribonucleotide biosynthetic process(GO:0009220) |
0.0 | 0.2 | GO:0046831 | regulation of RNA export from nucleus(GO:0046831) |
0.0 | 0.2 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
0.0 | 0.7 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
0.0 | 0.2 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.3 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
0.0 | 0.5 | GO:0007398 | ectoderm development(GO:0007398) |
0.0 | 0.7 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.0 | 0.2 | GO:0001964 | startle response(GO:0001964) |
0.0 | 0.7 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
0.0 | 4.6 | GO:0016568 | chromatin modification(GO:0016568) |
0.0 | 0.9 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.1 | GO:0042517 | positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517) |
0.0 | 0.3 | GO:1902591 | vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114) single-organism membrane budding(GO:1902591) |
0.0 | 0.5 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
0.0 | 0.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.0 | 0.2 | GO:0042987 | amyloid precursor protein catabolic process(GO:0042987) |
0.0 | 1.5 | GO:0034138 | toll-like receptor 1 signaling pathway(GO:0034130) toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138) |
0.0 | 0.0 | GO:0021903 | rostrocaudal neural tube patterning(GO:0021903) midbrain-hindbrain boundary development(GO:0030917) |
0.0 | 1.1 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403) |
0.0 | 0.4 | GO:0035338 | long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
0.0 | 0.2 | GO:0007625 | grooming behavior(GO:0007625) |
0.0 | 0.4 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
0.0 | 1.4 | GO:0008016 | regulation of heart contraction(GO:0008016) |
0.0 | 0.9 | GO:0007612 | learning(GO:0007612) |
0.0 | 0.1 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
0.0 | 0.6 | GO:0006040 | amino sugar metabolic process(GO:0006040) |
0.0 | 0.3 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
0.0 | 0.2 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.0 | 0.1 | GO:0000239 | pachytene(GO:0000239) |
0.0 | 0.1 | GO:0002063 | chondrocyte development(GO:0002063) |
0.0 | 0.4 | GO:0071824 | protein-DNA complex subunit organization(GO:0071824) |
0.0 | 0.0 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
0.0 | 0.4 | GO:0006413 | translational initiation(GO:0006413) |
0.0 | 0.5 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
0.0 | 0.2 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
0.0 | 1.4 | GO:0006836 | neurotransmitter transport(GO:0006836) |
0.0 | 0.3 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 6.9 | GO:0000808 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.2 | 1.7 | GO:0005642 | annulate lamellae(GO:0005642) |
0.2 | 0.7 | GO:0031213 | RSF complex(GO:0031213) |
0.2 | 2.6 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.2 | 1.2 | GO:0016589 | NURF complex(GO:0016589) |
0.2 | 1.7 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.1 | 9.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
0.1 | 0.8 | GO:0008537 | proteasome activator complex(GO:0008537) |
0.1 | 0.7 | GO:0019718 | obsolete rough microsome(GO:0019718) |
0.1 | 5.0 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
0.1 | 0.7 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
0.1 | 2.9 | GO:0071564 | npBAF complex(GO:0071564) |
0.1 | 7.4 | GO:0055037 | recycling endosome(GO:0055037) |
0.1 | 0.4 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
0.1 | 0.5 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.1 | 1.0 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.1 | 1.2 | GO:0032039 | integrator complex(GO:0032039) |
0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.1 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.1 | 0.5 | GO:0072487 | MSL complex(GO:0072487) |
0.1 | 0.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.1 | 0.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.1 | 0.9 | GO:0030673 | axolemma(GO:0030673) |
0.1 | 0.9 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
0.1 | 0.3 | GO:0097651 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651) |
0.1 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
0.1 | 0.6 | GO:0005638 | lamin filament(GO:0005638) |
0.1 | 1.2 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.1 | 0.4 | GO:0005954 | calcium- and calmodulin-dependent protein kinase complex(GO:0005954) |
0.1 | 0.7 | GO:0019908 | nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908) |
0.1 | 1.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.4 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 1.6 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
0.0 | 0.4 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.3 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.3 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 0.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 0.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.4 | GO:0000125 | PCAF complex(GO:0000125) |
0.0 | 1.3 | GO:0035097 | methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097) |
0.0 | 1.2 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 2.1 | GO:0000123 | histone acetyltransferase complex(GO:0000123) protein acetyltransferase complex(GO:0031248) acetyltransferase complex(GO:1902493) |
0.0 | 0.4 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
0.0 | 0.2 | GO:0005827 | polar microtubule(GO:0005827) |
0.0 | 0.3 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
0.0 | 0.1 | GO:0001741 | XY body(GO:0001741) |
0.0 | 1.5 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
0.0 | 4.9 | GO:0000785 | chromatin(GO:0000785) |
0.0 | 0.2 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.2 | GO:0042597 | NMDA selective glutamate receptor complex(GO:0017146) outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597) |
0.0 | 0.1 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.2 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.0 | 0.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
0.0 | 0.3 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.2 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.0 | 0.4 | GO:0044452 | nucleolar part(GO:0044452) |
0.0 | 0.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.3 | GO:0030315 | T-tubule(GO:0030315) |
0.0 | 1.6 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.0 | GO:0031143 | pseudopodium(GO:0031143) |
0.0 | 0.6 | GO:0042645 | mitochondrial nucleoid(GO:0042645) |
0.0 | 0.4 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.5 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 1.0 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.8 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.9 | GO:0034707 | chloride channel complex(GO:0034707) |
0.0 | 0.3 | GO:0000502 | proteasome complex(GO:0000502) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 7.2 | GO:0035403 | histone kinase activity (H3-T6 specific)(GO:0035403) |
1.1 | 3.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
0.7 | 6.9 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.4 | 1.3 | GO:0004756 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
0.3 | 1.3 | GO:0043398 | HLH domain binding(GO:0043398) |
0.3 | 0.9 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.3 | 4.0 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.3 | 13.9 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
0.3 | 2.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
0.3 | 0.9 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.3 | 1.0 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
0.2 | 2.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.2 | 0.7 | GO:0005224 | ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260) |
0.2 | 1.6 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.2 | 1.6 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.2 | 0.5 | GO:0031997 | N-terminal myristoylation domain binding(GO:0031997) |
0.2 | 0.5 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
0.2 | 1.6 | GO:0003701 | obsolete RNA polymerase I transcription factor activity(GO:0003701) |
0.2 | 0.6 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
0.2 | 0.8 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
0.2 | 0.5 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.2 | 0.5 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.1 | 2.2 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.1 | 0.4 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.5 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.1 | 1.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.1 | 0.8 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 1.0 | GO:0008159 | obsolete positive transcription elongation factor activity(GO:0008159) |
0.1 | 0.4 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
0.1 | 1.4 | GO:0061659 | ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
0.1 | 0.5 | GO:0052590 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
0.1 | 0.7 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 0.8 | GO:0004103 | choline kinase activity(GO:0004103) |
0.1 | 0.5 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.5 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 1.5 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.1 | 0.6 | GO:0045545 | syndecan binding(GO:0045545) |
0.1 | 0.5 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390) |
0.1 | 0.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
0.1 | 0.5 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 0.5 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.1 | 0.6 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.1 | 0.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
0.1 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
0.1 | 0.8 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.1 | 0.5 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.1 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.1 | 2.2 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.1 | 0.6 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.1 | 2.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.1 | 0.3 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
0.1 | 7.3 | GO:0003704 | obsolete specific RNA polymerase II transcription factor activity(GO:0003704) |
0.1 | 2.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.1 | 0.3 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.1 | 3.4 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
0.1 | 0.8 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
0.1 | 0.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.1 | 0.3 | GO:0003990 | acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104) |
0.1 | 1.3 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.1 | 0.6 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.1 | 0.5 | GO:0004969 | histamine receptor activity(GO:0004969) |
0.1 | 1.0 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.2 | GO:0035198 | miRNA binding(GO:0035198) |
0.1 | 0.8 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.1 | 0.1 | GO:0030618 | transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) |
0.1 | 0.2 | GO:0016731 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
0.1 | 0.4 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
0.1 | 0.7 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
0.1 | 1.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.1 | 0.7 | GO:0003711 | obsolete transcription elongation regulator activity(GO:0003711) |
0.1 | 1.5 | GO:0005234 | extracellular-glutamate-gated ion channel activity(GO:0005234) |
0.1 | 5.4 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
0.1 | 0.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 1.0 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 0.4 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 0.2 | GO:0016362 | activin receptor activity, type II(GO:0016362) |
0.0 | 1.4 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.8 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 0.3 | GO:0043559 | insulin binding(GO:0043559) |
0.0 | 0.4 | GO:0016565 | obsolete general transcriptional repressor activity(GO:0016565) |
0.0 | 0.4 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 7.6 | GO:0003682 | chromatin binding(GO:0003682) |
0.0 | 0.5 | GO:0008187 | poly-pyrimidine tract binding(GO:0008187) |
0.0 | 0.4 | GO:0015301 | anion:anion antiporter activity(GO:0015301) |
0.0 | 1.2 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
0.0 | 0.1 | GO:0043121 | neurotrophin binding(GO:0043121) |
0.0 | 0.3 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.0 | 0.2 | GO:0004046 | aminoacylase activity(GO:0004046) |
0.0 | 0.4 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093) basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099) |
0.0 | 0.6 | GO:0005542 | folic acid binding(GO:0005542) |
0.0 | 0.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
0.0 | 0.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 7.7 | GO:0016563 | obsolete transcription activator activity(GO:0016563) |
0.0 | 0.3 | GO:0030899 | calcium-dependent ATPase activity(GO:0030899) |
0.0 | 0.2 | GO:0030506 | ankyrin binding(GO:0030506) |
0.0 | 0.8 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.5 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.1 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.6 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.4 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 0.1 | GO:0003696 | satellite DNA binding(GO:0003696) methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0070628 | proteasome binding(GO:0070628) |
0.0 | 0.3 | GO:1901682 | sulfur compound transmembrane transporter activity(GO:1901682) |
0.0 | 7.2 | GO:0030695 | GTPase regulator activity(GO:0030695) |
0.0 | 0.1 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 0.0 | GO:0033765 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) |
0.0 | 0.3 | GO:0030332 | cyclin binding(GO:0030332) |
0.0 | 0.3 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 0.4 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 0.8 | GO:0004221 | obsolete ubiquitin thiolesterase activity(GO:0004221) |
0.0 | 0.6 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.0 | 0.1 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.4 | GO:0019003 | GDP binding(GO:0019003) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0005113 | patched binding(GO:0005113) |
0.0 | 1.0 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.4 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.3 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 1.6 | GO:0015631 | tubulin binding(GO:0015631) |
0.0 | 0.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.0 | 0.3 | GO:0004890 | GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917) |
0.0 | 16.7 | GO:0008270 | zinc ion binding(GO:0008270) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.6 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.1 | 3.1 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
0.1 | 1.6 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
0.0 | 2.3 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
0.0 | 0.7 | ST_B_CELL_ANTIGEN_RECEPTOR | B Cell Antigen Receptor |
0.0 | 0.6 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
0.0 | 0.6 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.1 | ST_ERK1_ERK2_MAPK_PATHWAY | ERK1/ERK2 MAPK Pathway |
0.0 | 0.3 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
0.0 | 0.2 | SA_PROGRAMMED_CELL_DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |