Motif ID: ZNF8

Z-value: 0.405


Transcription factors associated with ZNF8:

Gene SymbolEntrez IDGene Name
ZNF8 ENSG00000083842.8 ZNF8
ZNF8 ENSG00000273439.1 ZNF8



Activity profile for motif ZNF8.

activity profile for motif ZNF8


Sorted Z-values histogram for motif ZNF8

Sorted Z-values for motif ZNF8



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_106959718 0.600 ENST00000369066.3
 AIM1
absent in melanoma 1
chrX_+_128913906 0.492 ENST00000356892.3
 SASH3
SAM and SH3 domain containing 3
chr6_+_29691198 0.447 ENST00000440587.2
ENST00000434407.2
 HLA-F

major histocompatibility complex, class I, F

chr6_+_29691056 0.442 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
 HLA-F


major histocompatibility complex, class I, F


chr12_-_46662772 0.353 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
 SLC38A1


solute carrier family 38, member 1


chr2_-_172290482 0.339 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
 METTL8


methyltransferase like 8


chr19_+_35739782 0.271 ENST00000347609.4
 LSR
lipolysis stimulated lipoprotein receptor
chr19_+_35739897 0.266 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
 LSR


lipolysis stimulated lipoprotein receptor


chr17_+_75181292 0.252 ENST00000431431.2
 SEC14L1
SEC14-like 1 (S. cerevisiae)
chr6_+_53659746 0.245 ENST00000370888.1
 LRRC1
leucine rich repeat containing 1
chr22_+_37415676 0.221 ENST00000401419.3
 MPST
mercaptopyruvate sulfurtransferase
chr11_-_58345569 0.218 ENST00000528954.1
ENST00000528489.1
 LPXN

leupaxin

chr1_+_214161272 0.213 ENST00000498508.2
ENST00000366958.4
 PROX1

prospero homeobox 1

chr22_+_37415728 0.201 ENST00000404802.3
 MPST
mercaptopyruvate sulfurtransferase
chr22_+_37415700 0.192 ENST00000397129.1
 MPST
mercaptopyruvate sulfurtransferase
chr15_+_85523671 0.184 ENST00000310298.4
ENST00000557957.1
 PDE8A

phosphodiesterase 8A

chr22_+_37415776 0.177 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
 MPST


mercaptopyruvate sulfurtransferase


chr3_-_9994021 0.159 ENST00000411976.2
ENST00000412055.1
 PRRT3

proline-rich transmembrane protein 3

chr6_-_26056695 0.150 ENST00000343677.2
 HIST1H1C
histone cluster 1, H1c
chr7_+_117824086 0.147 ENST00000249299.2
ENST00000424702.1
 NAA38

N(alpha)-acetyltransferase 38, NatC auxiliary subunit

chr5_-_137911049 0.131 ENST00000297185.3
 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr13_+_53226963 0.118 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
 SUGT1


SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)


chr10_+_135192695 0.114 ENST00000368539.4
ENST00000278060.5
ENST00000357296.3
 PAOX


polyamine oxidase (exo-N4-amino)


chr2_+_169926047 0.104 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
 DHRS9


dehydrogenase/reductase (SDR family) member 9


chr1_-_235292250 0.101 ENST00000366607.4
 TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr11_-_46638720 0.099 ENST00000326737.3
 HARBI1
harbinger transposase derived 1
chr7_+_100303676 0.098 ENST00000303151.4
 POP7
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
chr17_+_48624450 0.098 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
 SPATA20


spermatogenesis associated 20


chr9_-_32552551 0.083 ENST00000360538.2
ENST00000379858.1
 TOPORS

topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase

chr13_+_21750780 0.080 ENST00000309594.4
 MRP63
mitochondrial ribosomal protein 63
chr10_-_1034237 0.075 ENST00000381466.1
 AL359878.1
Uncharacterized protein
chrX_+_129535937 0.074 ENST00000305536.6
ENST00000370947.1
 RBMX2

RNA binding motif protein, X-linked 2

chr19_+_37998031 0.068 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
 ZNF793


zinc finger protein 793


chr2_+_172290707 0.064 ENST00000375255.3
ENST00000539783.1
 DCAF17

DDB1 and CUL4 associated factor 17

chr8_-_109260897 0.057 ENST00000521297.1
ENST00000519030.1
ENST00000521440.1
ENST00000518345.1
ENST00000519627.1
ENST00000220849.5
 EIF3E





eukaryotic translation initiation factor 3, subunit E





chr2_+_87144738 0.056 ENST00000559485.1
 RGPD1
RANBP2-like and GRIP domain containing 1
chr2_+_198365122 0.045 ENST00000604458.1
 HSPE1-MOB4
HSPE1-MOB4 readthrough
chr16_+_21964662 0.044 ENST00000561553.1
ENST00000565331.1
 UQCRC2

ubiquinol-cytochrome c reductase core protein II

chr22_+_30163340 0.044 ENST00000330029.6
ENST00000401406.3
 UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr11_+_46638805 0.039 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
 ATG13


autophagy related 13


chr4_-_77069573 0.037 ENST00000264883.3
 NUP54
nucleoporin 54kDa
chr19_-_18392422 0.034 ENST00000252818.3
 JUND
jun D proto-oncogene
chr1_-_100715372 0.026 ENST00000370131.3
ENST00000370132.4
 DBT

dihydrolipoamide branched chain transacylase E2

chr2_-_240322643 0.025 ENST00000345617.3
 HDAC4
histone deacetylase 4
chr20_+_37377085 0.024 ENST00000243903.4
 ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr19_-_5903714 0.022 ENST00000252675.5
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000586349.1
ENST00000585661.1
 FUT5
NDUFA11


AC024592.12

fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa


Uncharacterized protein

chr8_+_145064233 0.012 ENST00000529301.1
ENST00000395068.4
 GRINA

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

chr14_+_51706886 0.010 ENST00000457354.2
 TMX1
thioredoxin-related transmembrane protein 1
chr5_+_10353780 0.006 ENST00000449913.2
ENST00000503788.1
ENST00000274140.5
 MARCH6


membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase


chr7_-_99698338 0.006 ENST00000354230.3
ENST00000425308.1
 MCM7

minichromosome maintenance complex component 7

chr1_-_70671216 0.005 ENST00000370952.3
 LRRC40
leucine rich repeat containing 40
chr1_+_70671363 0.000 ENST00000370951.1
ENST00000370950.3
ENST00000405432.1
ENST00000454435.2
 SRSF11



serine/arginine-rich splicing factor 11




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.1 0.2 GO:0055005 optic placode formation involved in camera-type eye formation(GO:0046619) ventricular cardiac myofibril assembly(GO:0055005) regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.1 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.1 0.9 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.4 GO:0005416 sodium:amino acid symporter activity(GO:0005283) cation:amino acid symporter activity(GO:0005416)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)