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ENCODE cell lines, expression (Ernst 2011)

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Results for AAUACUG

Z-value: 1.27

Motif logo

miRNA associated with seed AAUACUG

NamemiRBASE accession
MIMAT0000318
MIMAT0000617
MIMAT0001536

Activity profile of AAUACUG motif

Sorted Z-values of AAUACUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUACUG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_36036430 3.83 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr12_-_15942309 3.71 ENST00000544064.1
ENST00000543523.1
ENST00000536793.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_57045228 3.59 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_120170052 3.53 ENST00000295633.3
FSTL1
follistatin-like 1
chr3_-_123603137 3.40 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK
myosin light chain kinase
chr17_-_76870222 3.28 ENST00000585421.1
TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_151344172 3.18 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr16_-_65155833 2.61 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr10_-_81205373 2.37 ENST00000372336.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr3_-_134093395 2.12 ENST00000249883.5
AMOTL2
angiomotin like 2
chr5_-_121413974 2.11 ENST00000231004.4
LOX
lysyl oxidase
chr13_+_98794810 2.11 ENST00000595437.1
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr22_-_36236265 2.00 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_-_23932437 1.95 ENST00000331837.4
NDN
necdin, melanoma antigen (MAGE) family member
chr6_-_139695757 1.93 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr10_+_31608054 1.92 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr8_+_70378852 1.82 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1
sulfatase 1
chr19_-_11308190 1.82 ENST00000586659.1
ENST00000592903.1
ENST00000589359.1
ENST00000588724.1
ENST00000432929.2
KANK2
KN motif and ankyrin repeat domains 2
chr1_-_95392635 1.82 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr5_+_71403061 1.80 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr9_-_16870704 1.80 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr12_-_106641728 1.76 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr16_+_86544113 1.71 ENST00000262426.4
FOXF1
forkhead box F1
chr1_+_182992545 1.64 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chrY_+_15016725 1.58 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr2_+_102508955 1.57 ENST00000414004.2
FLJ20373
FLJ20373
chr13_+_27131887 1.48 ENST00000335327.5
WASF3
WAS protein family, member 3
chr11_+_12695944 1.48 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_-_48651648 1.44 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr14_-_61116168 1.35 ENST00000247182.6
SIX1
SIX homeobox 1
chr19_+_15218180 1.34 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr3_-_114790179 1.31 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr9_-_113800317 1.31 ENST00000374431.3
LPAR1
lysophosphatidic acid receptor 1
chr6_-_122792919 1.30 ENST00000339697.4
SERINC1
serine incorporator 1
chr6_-_167040731 1.29 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr5_-_172198190 1.28 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr13_-_40177261 1.26 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner
chr13_-_107187462 1.25 ENST00000245323.4
EFNB2
ephrin-B2
chr16_+_69221028 1.24 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_-_94285511 1.23 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr2_-_36825281 1.21 ENST00000405912.3
ENST00000379245.4
FEZ2
fasciculation and elongation protein zeta 2 (zygin II)
chr7_-_27183263 1.20 ENST00000222726.3
HOXA5
homeobox A5
chr16_-_70719925 1.19 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr7_-_35077653 1.18 ENST00000310974.4
DPY19L1
dpy-19-like 1 (C. elegans)
chr2_-_39664405 1.18 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr13_-_33859819 1.15 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_+_201170703 1.07 ENST00000358677.5
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr3_+_159557637 1.07 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr1_-_59249732 1.04 ENST00000371222.2
JUN
jun proto-oncogene
chr5_-_111093406 1.04 ENST00000379671.3
NREP
neuronal regeneration related protein
chr12_-_110434021 1.00 ENST00000355312.3
ENST00000551209.1
ENST00000550186.1
GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr9_+_470288 1.00 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr17_-_78450398 0.97 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr4_+_20255123 0.97 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr3_+_158991025 0.96 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr8_-_122653630 0.92 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr17_-_13505219 0.92 ENST00000284110.1
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr2_-_47168906 0.91 ENST00000444761.2
ENST00000409147.1
MCFD2
multiple coagulation factor deficiency 2
chr3_+_33155444 0.90 ENST00000320954.6
CRTAP
cartilage associated protein
chr1_+_25071848 0.90 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr1_+_84543734 0.88 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_+_17600576 0.88 ENST00000259963.3
FAM8A1
family with sequence similarity 8, member A1
chr16_-_4166186 0.88 ENST00000294016.3
ADCY9
adenylate cyclase 9
chr17_-_62658186 0.84 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr8_+_106330920 0.84 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr8_-_93115445 0.81 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_15901278 0.80 ENST00000399451.2
ANKRD28
ankyrin repeat domain 28
chrX_-_110038990 0.77 ENST00000372045.1
ENST00000394797.4
CHRDL1
chordin-like 1
chr1_-_52456352 0.77 ENST00000371655.3
RAB3B
RAB3B, member RAS oncogene family
chr7_-_103629963 0.76 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr6_+_1389989 0.75 ENST00000259806.1
FOXF2
forkhead box F2
chr14_+_62229075 0.75 ENST00000216294.4
SNAPC1
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr9_-_14314066 0.74 ENST00000397575.3
NFIB
nuclear factor I/B
chr5_-_57756087 0.73 ENST00000274289.3
PLK2
polo-like kinase 2
chr10_+_96162242 0.72 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr10_+_63661053 0.71 ENST00000279873.7
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr8_-_13372395 0.71 ENST00000276297.4
ENST00000511869.1
DLC1
deleted in liver cancer 1
chr14_+_59104741 0.68 ENST00000395153.3
ENST00000335867.4
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr14_-_53417732 0.68 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr4_+_156588350 0.68 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr9_+_132934835 0.66 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr11_+_73019282 0.65 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr2_-_216300784 0.65 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr6_-_52926539 0.65 ENST00000350082.5
ENST00000356971.3
ICK
intestinal cell (MAK-like) kinase
chr9_+_112810878 0.62 ENST00000434623.2
ENST00000374525.1
AKAP2
A kinase (PRKA) anchor protein 2
chr9_-_80646374 0.61 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr13_+_48807288 0.60 ENST00000378565.5
ITM2B
integral membrane protein 2B
chr6_-_57087042 0.60 ENST00000317483.3
RAB23
RAB23, member RAS oncogene family
chr11_-_9286921 0.59 ENST00000328194.3
DENND5A
DENN/MADD domain containing 5A
chr8_-_103668114 0.59 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr17_+_66508537 0.57 ENST00000392711.1
ENST00000585427.1
ENST00000589228.1
ENST00000536854.2
ENST00000588702.1
ENST00000589309.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr9_-_73029540 0.57 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr5_+_102201430 0.56 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr13_-_53422640 0.55 ENST00000338862.4
ENST00000377942.3
PCDH8
protocadherin 8
chr7_+_128379346 0.55 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr14_-_70883708 0.55 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr19_+_34745442 0.55 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
KIAA0355
chr10_-_30348439 0.55 ENST00000375377.1
KIAA1462
KIAA1462
chr7_-_111846435 0.54 ENST00000437633.1
ENST00000428084.1
DOCK4
dedicator of cytokinesis 4
chr11_-_66115032 0.54 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr1_+_183605200 0.53 ENST00000304685.4
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr3_-_124774802 0.53 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr2_+_148602058 0.53 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A
activin A receptor, type IIA
chr20_-_48099182 0.53 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr4_+_72204755 0.52 ENST00000512686.1
ENST00000340595.3
SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
chr12_+_5541267 0.52 ENST00000423158.3
NTF3
neurotrophin 3
chr12_-_46766577 0.52 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr9_+_112542572 0.51 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr7_+_94139105 0.50 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr5_+_17217669 0.50 ENST00000322611.3
BASP1
brain abundant, membrane attached signal protein 1
chr9_+_34990219 0.50 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_+_114827818 0.50 ENST00000420625.2
PLS3
plastin 3
chr8_-_49833978 0.49 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_-_57906362 0.48 ENST00000262644.4
IMPAD1
inositol monophosphatase domain containing 1
chr17_-_42908155 0.48 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1
gap junction protein, gamma 1, 45kDa
chr18_+_43304092 0.47 ENST00000321925.4
ENST00000587601.1
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr9_+_35538616 0.47 ENST00000455600.1
RUSC2
RUN and SH3 domain containing 2
chr10_-_126849068 0.45 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr9_+_132815985 0.45 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr2_-_227664474 0.45 ENST00000305123.5
IRS1
insulin receptor substrate 1
chrX_+_73641286 0.45 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr5_+_149887672 0.44 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_+_59063478 0.44 ENST00000559228.1
ENST00000450403.2
FAM63B
family with sequence similarity 63, member B
chr8_-_67579418 0.43 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr2_+_28615669 0.42 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr13_-_107220455 0.42 ENST00000400198.3
ARGLU1
arginine and glutamate rich 1
chr1_-_28969517 0.42 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr15_-_49338748 0.42 ENST00000559471.1
SECISBP2L
SECIS binding protein 2-like
chr6_-_108395907 0.41 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chr14_+_45431379 0.41 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B
family with sequence similarity 179, member B
chr10_-_104262426 0.40 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr11_+_129939779 0.40 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
APLP2
amyloid beta (A4) precursor-like protein 2
chr16_-_22385901 0.40 ENST00000268383.2
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr10_+_52751010 0.39 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr22_-_22307199 0.38 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr3_+_171758344 0.38 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr7_+_106685079 0.37 ENST00000265717.4
PRKAR2B
protein kinase, cAMP-dependent, regulatory, type II, beta
chr17_-_19771216 0.37 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr1_+_35734562 0.37 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr4_+_154125565 0.37 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr12_+_57522258 0.36 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr12_+_72666407 0.35 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chrX_-_15872914 0.35 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr11_+_118477144 0.34 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr21_+_40177143 0.34 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chrX_+_9983602 0.34 ENST00000380861.4
WWC3
WWC family member 3
chr16_-_87525651 0.34 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr3_+_150126101 0.33 ENST00000361875.3
ENST00000361136.2
TSC22D2
TSC22 domain family, member 2
chr1_+_28285973 0.32 ENST00000373884.5
XKR8
XK, Kell blood group complex subunit-related family, member 8
chr1_-_1624083 0.32 ENST00000378662.1
ENST00000234800.6
SLC35E2B
solute carrier family 35, member E2B
chr13_-_36920420 0.32 ENST00000438666.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr4_-_55991752 0.31 ENST00000263923.4
KDR
kinase insert domain receptor (a type III receptor tyrosine kinase)
chrX_+_9754461 0.31 ENST00000380913.3
SHROOM2
shroom family member 2
chr2_-_11484710 0.31 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chrX_-_11445856 0.31 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr3_-_149688896 0.30 ENST00000239940.7
PFN2
profilin 2
chr13_-_103451307 0.30 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr6_+_170102210 0.29 ENST00000439249.1
ENST00000332290.2
C6orf120
chromosome 6 open reading frame 120
chr10_+_60094735 0.29 ENST00000373910.4
UBE2D1
ubiquitin-conjugating enzyme E2D 1
chr17_+_41323204 0.28 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1
neighbor of BRCA1 gene 1
chr17_+_72983674 0.28 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr4_-_85887503 0.28 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WDFY3
WD repeat and FYVE domain containing 3
chr2_-_86564776 0.28 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr3_-_128212016 0.28 ENST00000498200.1
ENST00000341105.2
GATA2
GATA binding protein 2
chr1_-_109940550 0.28 ENST00000256637.6
SORT1
sortilin 1
chr10_+_120967072 0.27 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr16_-_67281413 0.27 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr21_-_15755446 0.27 ENST00000544452.1
ENST00000285667.3
HSPA13
heat shock protein 70kDa family, member 13
chr11_-_62314268 0.27 ENST00000257247.7
ENST00000531324.1
ENST00000378024.4
AHNAK
AHNAK nucleoprotein
chr3_-_33138286 0.27 ENST00000416695.2
ENST00000342462.4
ENST00000399402.3
TMPPE
GLB1
transmembrane protein with metallophosphoesterase domain
galactosidase, beta 1
chr9_-_23821273 0.26 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr9_-_74980113 0.26 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr7_-_42276612 0.25 ENST00000395925.3
ENST00000437480.1
GLI3
GLI family zinc finger 3
chr19_-_40791302 0.25 ENST00000392038.2
ENST00000578123.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_+_10857885 0.25 ENST00000254488.2
ENST00000454147.1
SLC6A11
solute carrier family 6 (neurotransmitter transporter), member 11
chr13_-_29069232 0.25 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr12_-_57824739 0.25 ENST00000347140.3
ENST00000402412.1
R3HDM2
R3H domain containing 2
chr14_-_73925225 0.23 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
NUMB
numb homolog (Drosophila)
chr3_-_185826855 0.23 ENST00000306376.5
ETV5
ets variant 5
chr20_-_3996036 0.22 ENST00000336095.6
RNF24
ring finger protein 24
chr15_+_62853562 0.22 ENST00000561311.1
TLN2
talin 2
chr1_-_208417620 0.22 ENST00000367033.3
PLXNA2
plexin A2
chr5_+_38846101 0.22 ENST00000274276.3
OSMR
oncostatin M receptor
chr7_-_41742697 0.22 ENST00000242208.4
INHBA
inhibin, beta A
chr18_+_67956135 0.22 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chrX_-_20284958 0.22 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr12_-_118797475 0.20 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr11_+_111807863 0.20 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr10_+_104535994 0.20 ENST00000369889.4
WBP1L
WW domain binding protein 1-like
chr14_+_67707826 0.20 ENST00000261681.4
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr10_+_111767720 0.20 ENST00000356080.4
ENST00000277900.8
ADD3
adducin 3 (gamma)
chr20_-_8000426 0.20 ENST00000527925.1
ENST00000246024.2
TMX4
thioredoxin-related transmembrane protein 4
chr19_+_49617581 0.20 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr3_-_27498235 0.19 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_-_240775447 0.19 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr8_+_107670064 0.19 ENST00000312046.6
OXR1
oxidation resistance 1
chr10_-_27443155 0.19 ENST00000427324.1
ENST00000326799.3
YME1L1
YME1-like 1 ATPase
chr17_-_36956155 0.19 ENST00000269554.3
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chrX_-_6146876 0.19 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr3_-_167813672 0.19 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.8 2.3 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.7 3.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.6 1.7 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.5 2.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.5 1.9 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.5 1.4 GO:0061055 myotome development(GO:0061055) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.4 3.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.4 3.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.4 1.2 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 3.6 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.3 2.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.3 1.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 0.9 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.3 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 1.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.5 GO:0032328 alanine transport(GO:0032328)
0.3 1.3 GO:0097338 response to clozapine(GO:0097338)
0.2 0.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602) semicircular canal morphogenesis(GO:0048752)
0.2 1.8 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 1.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.2 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.8 GO:0048749 compound eye development(GO:0048749)
0.2 0.8 GO:0097477 NMDA glutamate receptor clustering(GO:0097114) spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 0.9 GO:1900127 renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.2 2.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.5 GO:0060872 semicircular canal development(GO:0060872)
0.2 0.3 GO:1903055 basement membrane assembly(GO:0070831) positive regulation of extracellular matrix organization(GO:1903055)
0.2 0.6 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 1.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.8 GO:0051586 peptidyl-cysteine methylation(GO:0018125) positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1 0.6 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.5 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 1.8 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.5 GO:0042713 sperm ejaculation(GO:0042713)
0.1 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.5 GO:0086053 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.7 GO:0061525 hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619) hindgut development(GO:0061525)
0.1 0.7 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.3 GO:0015825 L-serine transport(GO:0015825)
0.1 0.7 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 0.5 GO:2001076 regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.4 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 1.8 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 3.8 GO:0035329 hippo signaling(GO:0035329)
0.1 0.2 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 0.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 1.9 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.3 GO:0035973 aggrephagy(GO:0035973)
0.1 1.6 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.1 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.7 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.3 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.8 GO:0003416 endochondral bone growth(GO:0003416)
0.1 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 1.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.4 GO:0048702 protein sulfation(GO:0006477) embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0003285 septum secundum development(GO:0003285)
0.0 0.1 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.0 0.1 GO:2000705 histone H3-T6 phosphorylation(GO:0035408) dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 1.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.4 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 1.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) regulation of muscle hyperplasia(GO:0014738) negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.0 0.7 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.5 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.7 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0072719 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0070933 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) peptidyl-lysine deacetylation(GO:0034983) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.8 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.7 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0046476 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) glycosylceramide biosynthetic process(GO:0046476)
0.0 1.0 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 1.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0032455 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.0 0.5 GO:0001756 somitogenesis(GO:0001756)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0016577 histone demethylation(GO:0016577)
0.0 1.7 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0048477 oogenesis(GO:0048477)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.3 1.5 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 3.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 0.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.9 GO:0042599 lamellar body(GO:0042599)
0.1 0.4 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.1 0.7 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 3.2 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 5.1 GO:0043197 dendritic spine(GO:0043197)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 5.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 2.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 1.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 2.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 3.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 3.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.5 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 1.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 0.9 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 6.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 0.8 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.2 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.9 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.6 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.5 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0086077 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.5 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.5 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 2.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.4 GO:0042954 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.1 2.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 5.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.0 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.3 GO:0016936 galactoside binding(GO:0016936)
0.1 1.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 1.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.9 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 0.3 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 3.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.6 PID AURORA B PATHWAY Aurora B signaling
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 3.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 3.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 2.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 2.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 5.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling