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ENCODE cell lines, expression (Ernst 2011)

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Results for AAUCUCU

Z-value: 0.30

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miRNA associated with seed AAUCUCU

NamemiRBASE accession
hsa-miR-216b-5p
MIMAT0004959

Activity profile of AAUCUCU motif

Sorted Z-values of AAUCUCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_+_11206925 0.52 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
 CELF2
 CUGBP, Elav-like family member 2
chr4_-_105416039 0.49 ENST00000394767.2
 CXXC4
 CXXC finger protein 4
chr14_+_71108460 0.36 ENST00000256367.2
 TTC9
 tetratricopeptide repeat domain 9
chr9_-_20622478 0.33 ENST00000355930.6
ENST00000380338.4
 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_42749759 0.22 ENST00000314073.5
 GLTSCR1L
 GLTSCR1-like
chr14_+_57735614 0.20 ENST00000261558.3
 AP5M1
 adaptor-related protein complex 5, mu 1 subunit
chr12_+_60083118 0.19 ENST00000261187.4
ENST00000543448.1
 SLC16A7
 solute carrier family 16 (monocarboxylate transporter), member 7
chr6_+_114178512 0.17 ENST00000368635.4
 MARCKS
 myristoylated alanine-rich protein kinase C substrate
chr2_+_48010221 0.15 ENST00000234420.5
 MSH6
 mutS homolog 6
chr7_+_21467642 0.14 ENST00000222584.3
ENST00000432066.2
 SP4
 Sp4 transcription factor
chr13_-_31038370 0.13 ENST00000399489.1
ENST00000339872.4
 HMGB1
 high mobility group box 1
chr1_+_63788730 0.10 ENST00000371116.2
 FOXD3
 forkhead box D3
chr12_+_111471828 0.09 ENST00000261726.6
 CUX2
 cut-like homeobox 2
chr19_-_4066890 0.09 ENST00000322357.4
 ZBTB7A
 zinc finger and BTB domain containing 7A
chr8_+_48920960 0.09 ENST00000523111.2
ENST00000523432.1
ENST00000521346.1
ENST00000517630.1
 UBE2V2
 ubiquitin-conjugating enzyme E2 variant 2
chr3_-_113465065 0.08 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
 NAA50
 N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_+_99916765 0.05 ENST00000296411.6
 METAP1
 methionyl aminopeptidase 1
chr7_+_35840542 0.05 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
 SEPT7
 septin 7
chr10_-_104474128 0.04 ENST00000260746.5
 ARL3
 ADP-ribosylation factor-like 3
chr17_+_30677136 0.03 ENST00000394670.4
ENST00000321233.6
ENST00000394673.2
ENST00000341711.6
ENST00000579634.1
ENST00000580759.1
ENST00000342555.6
ENST00000577908.1
ENST00000394679.5
ENST00000582165.1
 ZNF207
 zinc finger protein 207
chrX_+_122993827 0.03 ENST00000371199.3
 XIAP
 X-linked inhibitor of apoptosis
chr8_+_76452097 0.02 ENST00000396423.2
 HNF4G
 hepatocyte nuclear factor 4, gamma
chr15_+_73344791 0.02 ENST00000261908.6
 NEO1
 neogenin 1
chr16_-_46723066 0.02 ENST00000299138.7
 VPS35
 vacuolar protein sorting 35 homolog (S. cerevisiae)
chr5_+_149109825 0.02 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
 PPARGC1B
 peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr2_-_242212227 0.02 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
 HDLBP
 high density lipoprotein binding protein

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0002424 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.3 GO:0007379 segment specification(GO:0007379) positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters