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ENCODE cell lines, expression (Ernst 2011)

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Results for AAUGCCC

Z-value: 0.39

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miRNA associated with seed AAUGCCC

NamemiRBASE accession
hsa-miR-365a-3p
MIMAT0000710
hsa-miR-365b-3p
MIMAT0022834

Activity profile of AAUGCCC motif

Sorted Z-values of AAUGCCC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_123603137 0.43 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
 MYLK
 myosin light chain kinase
chr6_-_134639180 0.43 ENST00000367858.5
 SGK1
 serum/glucocorticoid regulated kinase 1
chr15_+_52121822 0.39 ENST00000558455.1
ENST00000308580.7
 TMOD3
 tropomodulin 3 (ubiquitous)
chr12_+_72666407 0.37 ENST00000261180.4
 TRHDE
 thyrotropin-releasing hormone degrading enzyme
chr7_-_83824169 0.32 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr21_-_28217721 0.31 ENST00000284984.3
 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_-_62149433 0.28 ENST00000280772.2
 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
chr9_-_117880477 0.27 ENST00000534839.1
ENST00000340094.3
ENST00000535648.1
ENST00000346706.3
ENST00000345230.3
ENST00000350763.4
 TNC
 tenascin C
chr2_+_46926048 0.25 ENST00000306503.5
 SOCS5
 suppressor of cytokine signaling 5
chr5_-_43313574 0.24 ENST00000325110.6
ENST00000433297.2
 HMGCS1
 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr11_+_34642656 0.23 ENST00000257831.3
ENST00000450654.2
 EHF
 ets homologous factor
chr1_-_153588334 0.21 ENST00000476873.1
 S100A14
 S100 calcium binding protein A14
chr8_+_54764346 0.21 ENST00000297313.3
ENST00000344277.6
 RGS20
 regulator of G-protein signaling 20
chr9_-_14314066 0.20 ENST00000397575.3
 NFIB
 nuclear factor I/B
chr15_+_96873921 0.19 ENST00000394166.3
 NR2F2
 nuclear receptor subfamily 2, group F, member 2
chr5_+_133861790 0.19 ENST00000395003.1
 PHF15
 jade family PHD finger 2
chr2_-_183903133 0.19 ENST00000361354.4
 NCKAP1
 NCK-associated protein 1
chr4_-_11431389 0.19 ENST00000002596.5
 HS3ST1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr10_+_1095416 0.18 ENST00000358220.1
 WDR37
 WD repeat domain 37
chr4_-_149365827 0.16 ENST00000344721.4
 NR3C2
 nuclear receptor subfamily 3, group C, member 2
chr1_+_2160134 0.15 ENST00000378536.4
 SKI
 v-ski avian sarcoma viral oncogene homolog
chr1_-_23857698 0.15 ENST00000361729.2
 E2F2
 E2F transcription factor 2
chr3_-_33481835 0.14 ENST00000283629.3
 UBP1
 upstream binding protein 1 (LBP-1a)
chr2_-_200322723 0.14 ENST00000417098.1
 SATB2
 SATB homeobox 2
chr7_-_150652924 0.14 ENST00000330883.4
 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_-_105615164 0.12 ENST00000355946.2
ENST00000369774.4
 SH3PXD2A
 SH3 and PX domains 2A
chr22_+_32340481 0.12 ENST00000397492.1
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr16_-_79634595 0.12 ENST00000326043.4
ENST00000393350.1
 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr14_-_99737565 0.11 ENST00000357195.3
 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
chr7_-_111846435 0.11 ENST00000437633.1
ENST00000428084.1
 DOCK4
 dedicator of cytokinesis 4
chr10_+_52751010 0.11 ENST00000373985.1
 PRKG1
 protein kinase, cGMP-dependent, type I
chrX_-_109561294 0.11 ENST00000372059.2
ENST00000262844.5
 AMMECR1
 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_-_142783175 0.11 ENST00000231509.3
ENST00000394464.2
 NR3C1
 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr11_+_64073699 0.11 ENST00000405666.1
ENST00000468670.1
 ESRRA
 estrogen-related receptor alpha
chr2_+_46524537 0.11 ENST00000263734.3
 EPAS1
 endothelial PAS domain protein 1
chr3_-_48632593 0.10 ENST00000454817.1
ENST00000328333.8
 COL7A1
 collagen, type VII, alpha 1
chr7_-_14029515 0.09 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
 ETV1
 ets variant 1
chr1_-_244013384 0.09 ENST00000366539.1
 AKT3
 v-akt murine thymoma viral oncogene homolog 3
chr2_-_153574480 0.09 ENST00000410080.1
 PRPF40A
 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr11_-_27528301 0.09 ENST00000524596.1
ENST00000278193.2
 LIN7C
 lin-7 homolog C (C. elegans)
chr17_+_68165657 0.09 ENST00000243457.3
 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
chr5_+_74632993 0.08 ENST00000287936.4
 HMGCR
 3-hydroxy-3-methylglutaryl-CoA reductase
chr3_-_113465065 0.08 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
 NAA50
 N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_173600671 0.08 ENST00000409036.1
 RAPGEF4
 Rap guanine nucleotide exchange factor (GEF) 4
chr7_-_151217001 0.08 ENST00000262187.5
 RHEB
 Ras homolog enriched in brain
chr15_+_41523335 0.08 ENST00000334660.5
 CHP1
 calcineurin-like EF-hand protein 1
chr17_-_19771216 0.07 ENST00000395544.4
 ULK2
 unc-51 like autophagy activating kinase 2
chr10_-_103874692 0.07 ENST00000361198.5
 LDB1
 LIM domain binding 1
chrX_+_69664706 0.06 ENST00000194900.4
ENST00000374360.3
 DLG3
 discs, large homolog 3 (Drosophila)
chr12_+_56137064 0.06 ENST00000257868.5
ENST00000546799.1
 GDF11
 growth differentiation factor 11
chr11_-_102714534 0.06 ENST00000299855.5
 MMP3
 matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr3_-_55523966 0.06 ENST00000474267.1
 WNT5A
 wingless-type MMTV integration site family, member 5A
chr11_-_68609377 0.06 ENST00000265641.5
ENST00000376618.2
 CPT1A
 carnitine palmitoyltransferase 1A (liver)
chr1_-_155211017 0.06 ENST00000536770.1
ENST00000368373.3
 GBA
 glucosidase, beta, acid
chr13_-_21476900 0.05 ENST00000400602.2
ENST00000255305.6
 XPO4
 exportin 4
chr12_-_67072714 0.05 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
 GRIP1
 glutamate receptor interacting protein 1
chr1_+_2985760 0.05 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
 PRDM16
 PR domain containing 16
chr20_-_39317868 0.05 ENST00000373313.2
 MAFB
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr2_-_157189180 0.05 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
 NR4A2
 nuclear receptor subfamily 4, group A, member 2
chr2_-_43453734 0.05 ENST00000282388.3
 ZFP36L2
 ZFP36 ring finger protein-like 2
chr1_-_38325256 0.05 ENST00000373036.4
 MTF1
 metal-regulatory transcription factor 1
chr20_-_1974692 0.05 ENST00000217305.2
ENST00000539905.1
 PDYN
 prodynorphin
chr9_+_128024067 0.04 ENST00000461379.1
ENST00000394084.1
ENST00000394105.2
ENST00000470056.1
ENST00000394104.2
ENST00000265956.4
ENST00000394083.2
ENST00000495955.1
ENST00000467750.1
ENST00000297933.6
 GAPVD1
 GTPase activating protein and VPS9 domains 1
chr13_+_114238997 0.04 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr22_+_21271714 0.04 ENST00000354336.3
 CRKL
 v-crk avian sarcoma virus CT10 oncogene homolog-like
chr15_-_64995399 0.04 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
 OAZ2
 ornithine decarboxylase antizyme 2
chrX_+_73641286 0.04 ENST00000587091.1
 SLC16A2
 solute carrier family 16, member 2 (thyroid hormone transporter)
chr3_+_14989076 0.04 ENST00000413118.1
ENST00000425241.1
 NR2C2
 nuclear receptor subfamily 2, group C, member 2
chr3_+_101292939 0.04 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
 PCNP
 PEST proteolytic signal containing nuclear protein
chr3_+_152552685 0.04 ENST00000305097.3
 P2RY1
 purinergic receptor P2Y, G-protein coupled, 1
chr1_+_156589051 0.04 ENST00000255039.1
 HAPLN2
 hyaluronan and proteoglycan link protein 2
chr10_+_22605304 0.04 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
 COMMD3-BMI1
COMMD3
 COMMD3-BMI1 readthrough
COMM domain containing 3
chr7_+_139044621 0.04 ENST00000354926.4
 C7orf55-LUC7L2
 C7orf55-LUC7L2 readthrough
chr4_+_41992489 0.04 ENST00000264451.7
 SLC30A9
 solute carrier family 30 (zinc transporter), member 9
chr17_+_36508111 0.04 ENST00000331159.5
ENST00000577233.1
 SOCS7
 suppressor of cytokine signaling 7
chr11_+_66036004 0.04 ENST00000311481.6
ENST00000527397.1
 RAB1B
 RAB1B, member RAS oncogene family
chr10_+_22610124 0.04 ENST00000376663.3
 BMI1
 BMI1 polycomb ring finger oncogene
chr2_+_192542850 0.03 ENST00000410026.2
 NABP1
 nucleic acid binding protein 1
chr10_+_101419187 0.03 ENST00000370489.4
 ENTPD7
 ectonucleoside triphosphate diphosphohydrolase 7
chr1_+_64239657 0.03 ENST00000371080.1
ENST00000371079.1
 ROR1
 receptor tyrosine kinase-like orphan receptor 1
chr2_-_208634287 0.03 ENST00000295417.3
 FZD5
 frizzled family receptor 5
chr1_-_35658736 0.03 ENST00000357214.5
 SFPQ
 splicing factor proline/glutamine-rich
chr3_-_48885228 0.03 ENST00000454963.1
ENST00000296446.8
ENST00000419216.1
ENST00000265563.8
 PRKAR2A
 protein kinase, cAMP-dependent, regulatory, type II, alpha
chr11_+_63606373 0.03 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
 MARK2
 MAP/microtubule affinity-regulating kinase 2
chr22_-_42017021 0.03 ENST00000263256.6
 DESI1
 desumoylating isopeptidase 1
chr4_+_139936905 0.03 ENST00000280614.2
 CCRN4L
 CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr20_+_56884752 0.03 ENST00000244040.3
 RAB22A
 RAB22A, member RAS oncogene family
chr1_+_161284047 0.03 ENST00000367975.2
ENST00000342751.4
ENST00000432287.2
ENST00000392169.2
ENST00000513009.1
 SDHC
 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
chr12_-_89918522 0.03 ENST00000529983.2
 GALNT4
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr8_+_1449532 0.03 ENST00000421627.2
 DLGAP2
 discs, large (Drosophila) homolog-associated protein 2
chrX_-_83442915 0.02 ENST00000262752.2
ENST00000543399.1
 RPS6KA6
 ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr12_+_66217911 0.02 ENST00000403681.2
 HMGA2
 high mobility group AT-hook 2
chr1_-_155881156 0.02 ENST00000539040.1
ENST00000368323.3
 RIT1
 Ras-like without CAAX 1
chr10_-_120101804 0.02 ENST00000369183.4
ENST00000369172.4
 FAM204A
 family with sequence similarity 204, member A
chr2_+_155554797 0.02 ENST00000295101.2
 KCNJ3
 potassium inwardly-rectifying channel, subfamily J, member 3
chr10_-_120514720 0.02 ENST00000369151.3
ENST00000340214.4
 CACUL1
 CDK2-associated, cullin domain 1
chr18_+_43753974 0.02 ENST00000282059.6
ENST00000321319.6
 C18orf25
 chromosome 18 open reading frame 25
chr2_-_39348137 0.02 ENST00000426016.1
 SOS1
 son of sevenless homolog 1 (Drosophila)
chr8_+_59323823 0.02 ENST00000399598.2
 UBXN2B
 UBX domain protein 2B
chr1_+_202976493 0.02 ENST00000367242.3
 TMEM183A
 transmembrane protein 183A
chr1_-_205719295 0.01 ENST00000367142.4
 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_39339777 0.01 ENST00000397572.2
 MYCBP
 MYC binding protein
chr12_-_75905374 0.01 ENST00000438169.2
ENST00000229214.4
 KRR1
 KRR1, small subunit (SSU) processome component, homolog (yeast)
chr17_-_40273348 0.01 ENST00000225916.5
 KAT2A
 K(lysine) acetyltransferase 2A
chr12_+_2162447 0.01 ENST00000335762.5
ENST00000399655.1
 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
chr4_-_103748880 0.01 ENST00000453744.2
ENST00000349311.8
 UBE2D3
 ubiquitin-conjugating enzyme E2D 3
chr2_+_131862900 0.01 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
 PLEKHB2
 pleckstrin homology domain containing, family B (evectins) member 2
chr1_+_36273743 0.01 ENST00000373210.3
 AGO4
 argonaute RISC catalytic component 4
chr12_+_56401268 0.01 ENST00000262032.5
 IKZF4
 IKAROS family zinc finger 4 (Eos)
chr9_+_130548297 0.01 ENST00000373264.4
 CDK9
 cyclin-dependent kinase 9
chr12_-_89919965 0.01 ENST00000548729.1
 POC1B-GALNT4
 POC1B-GALNT4 readthrough
chr7_+_6414128 0.01 ENST00000348035.4
ENST00000356142.4
 RAC1
 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
chr17_-_56084578 0.01 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
 SRSF1
 serine/arginine-rich splicing factor 1
chr9_+_131445928 0.01 ENST00000372692.4
 SET
 SET nuclear oncogene
chr12_+_69864129 0.01 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
 FRS2
 fibroblast growth factor receptor substrate 2
chr1_+_145611010 0.01 ENST00000369291.5
 RNF115
 ring finger protein 115
chr7_-_32931387 0.01 ENST00000304056.4
 KBTBD2
 kelch repeat and BTB (POZ) domain containing 2
chr8_-_57906362 0.01 ENST00000262644.4
 IMPAD1
 inositol monophosphatase domain containing 1
chr12_-_82153087 0.00 ENST00000547623.1
ENST00000549396.1
 PPFIA2
 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_+_48002076 0.00 ENST00000418331.2
ENST00000440289.2
 PTPRJ
 protein tyrosine phosphatase, receptor type, J
chr7_+_28452130 0.00 ENST00000357727.2
 CREB5
 cAMP responsive element binding protein 5
chrX_+_77359671 0.00 ENST00000373316.4
 PGK1
 phosphoglycerate kinase 1
chr3_+_51575596 0.00 ENST00000409535.2
 RAD54L2
 RAD54-like 2 (S. cerevisiae)
chr19_+_46850251 0.00 ENST00000012443.4
 PPP5C
 protein phosphatase 5, catalytic subunit
chr18_+_32073253 0.00 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA
 dystrobrevin, alpha

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.3 GO:0048880 sensory system development(GO:0048880)
0.1 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.2 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.2 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0003213 cardiac right atrium morphogenesis(GO:0003213)
0.0 0.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0071372 response to light intensity(GO:0009642) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis