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ENCODE cell lines, expression (Ernst 2011)

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Results for AGUGGUU

Z-value: 0.98

Motif logo

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miRNA associated with seed AGUGGUU

NamemiRBASE accession
hsa-miR-140-5p
MIMAT0000431

Activity profile of AGUGGUU motif

Sorted Z-values of AGUGGUU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGGUU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_81071684 2.80 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
 KIAA1199
 KIAA1199
chr1_-_20812690 2.47 ENST00000375078.3
 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
chr15_-_48937982 2.30 ENST00000316623.5
 FBN1
 fibrillin 1
chr21_-_28338732 1.95 ENST00000284987.5
 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr3_-_149688896 1.84 ENST00000239940.7
 PFN2
 profilin 2
chr5_+_32788945 1.66 ENST00000326958.1
 AC026703.1
 AC026703.1
chr1_-_68299130 1.63 ENST00000370982.3
 GNG12
 guanine nucleotide binding protein (G protein), gamma 12
chr4_+_55095264 1.61 ENST00000257290.5
 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
chr5_-_172756506 1.60 ENST00000265087.4
 STC2
 stanniocalcin 2
chr8_+_26435359 1.59 ENST00000311151.5
 DPYSL2
 dihydropyrimidinase-like 2
chr1_+_182992545 1.59 ENST00000258341.4
 LAMC1
 laminin, gamma 1 (formerly LAMB2)
chr4_+_124320665 1.54 ENST00000394339.2
 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr8_+_70378852 1.53 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
 SULF1
 sulfatase 1
chr16_+_69221028 1.51 ENST00000336278.4
 SNTB2
 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr2_-_217560248 1.42 ENST00000233813.4
 IGFBP5
 insulin-like growth factor binding protein 5
chr9_+_112810878 1.24 ENST00000434623.2
ENST00000374525.1
 AKAP2
 A kinase (PRKA) anchor protein 2
chr12_-_7245125 1.13 ENST00000542285.1
ENST00000540610.1
 C1R
 complement component 1, r subcomponent
chr3_-_124774802 1.09 ENST00000311127.4
 HEG1
 heart development protein with EGF-like domains 1
chr9_+_112542572 1.06 ENST00000374530.3
 PALM2-AKAP2
 PALM2-AKAP2 readthrough
chr3_-_114790179 1.03 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr14_+_85996471 1.03 ENST00000330753.4
 FLRT2
 fibronectin leucine rich transmembrane protein 2
chr1_+_78470530 1.01 ENST00000370763.5
 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_+_143929307 1.01 ENST00000427704.2
ENST00000305766.6
 PHACTR2
 phosphatase and actin regulator 2
chr11_+_12695944 0.99 ENST00000361905.4
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr1_+_11994715 0.98 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
 PLOD1
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr3_-_46037299 0.95 ENST00000296137.2
 FYCO1
 FYVE and coiled-coil domain containing 1
chr5_+_32711419 0.95 ENST00000265074.8
 NPR3
 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr2_-_183903133 0.95 ENST00000361354.4
 NCKAP1
 NCK-associated protein 1
chr6_-_82462425 0.94 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
 FAM46A
 family with sequence similarity 46, member A
chr7_-_30029367 0.92 ENST00000242059.5
 SCRN1
 secernin 1
chr9_-_73029540 0.88 ENST00000377126.2
 KLF9
 Kruppel-like factor 9
chr5_-_16936340 0.81 ENST00000507288.1
ENST00000513610.1
 MYO10
 myosin X
chr10_+_60272814 0.81 ENST00000373886.3
 BICC1
 bicaudal C homolog 1 (Drosophila)
chr5_-_127873659 0.80 ENST00000262464.4
 FBN2
 fibrillin 2
chr2_+_242255275 0.79 ENST00000391971.2
 SEPT2
 septin 2
chr8_+_38854418 0.76 ENST00000481513.1
ENST00000487273.2
 ADAM9
 ADAM metallopeptidase domain 9
chr1_+_160313062 0.71 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
 NCSTN
 nicastrin
chrX_+_37208521 0.71 ENST00000378628.4
 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
chr4_-_111544254 0.68 ENST00000306732.3
 PITX2
 paired-like homeodomain 2
chr1_+_82266053 0.61 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
 LPHN2
 latrophilin 2
chr9_+_120466650 0.59 ENST00000355622.6
 TLR4
 toll-like receptor 4
chr16_-_66785699 0.59 ENST00000258198.2
 DYNC1LI2
 dynein, cytoplasmic 1, light intermediate chain 2
chr14_-_55878538 0.59 ENST00000247178.5
 ATG14
 autophagy related 14
chr10_+_96162242 0.56 ENST00000225235.4
 TBC1D12
 TBC1 domain family, member 12
chr12_-_46766577 0.53 ENST00000256689.5
 SLC38A2
 solute carrier family 38, member 2
chr5_-_77844974 0.52 ENST00000515007.2
 LHFPL2
 lipoma HMGIC fusion partner-like 2
chr22_-_36784035 0.51 ENST00000216181.5
 MYH9
 myosin, heavy chain 9, non-muscle
chr15_-_30114622 0.49 ENST00000495972.2
ENST00000346128.6
 TJP1
 tight junction protein 1
chr4_-_85887503 0.49 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
 WDFY3
 WD repeat and FYVE domain containing 3
chr11_+_46299199 0.45 ENST00000529193.1
ENST00000288400.3
 CREB3L1
 cAMP responsive element binding protein 3-like 1
chr15_-_56757329 0.45 ENST00000260453.3
 MNS1
 meiosis-specific nuclear structural 1
chrX_+_107069063 0.43 ENST00000262843.6
 MID2
 midline 2
chr6_-_110500905 0.43 ENST00000392587.2
 WASF1
 WAS protein family, member 1
chr4_-_54930790 0.42 ENST00000263921.3
 CHIC2
 cysteine-rich hydrophobic domain 2
chr14_-_82000140 0.41 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L
 sel-1 suppressor of lin-12-like (C. elegans)
chr5_+_149887672 0.40 ENST00000261797.6
 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr14_+_23775971 0.38 ENST00000250405.5
 BCL2L2
 BCL2-like 2
chr7_+_128379346 0.37 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
 CALU
 calumenin
chr1_+_64239657 0.36 ENST00000371080.1
ENST00000371079.1
 ROR1
 receptor tyrosine kinase-like orphan receptor 1
chr9_+_132934835 0.36 ENST00000372398.3
 NCS1
 neuronal calcium sensor 1
chr19_+_48972459 0.35 ENST00000427476.1
 CYTH2
 cytohesin 2
chr9_+_132815985 0.34 ENST00000372410.3
 GPR107
 G protein-coupled receptor 107
chr7_+_39663061 0.34 ENST00000005257.2
 RALA
 v-ral simian leukemia viral oncogene homolog A (ras related)
chr3_-_50396978 0.33 ENST00000266025.3
 TMEM115
 transmembrane protein 115
chrX_-_119603138 0.33 ENST00000200639.4
ENST00000371335.4
ENST00000538785.1
ENST00000434600.2
 LAMP2
 lysosomal-associated membrane protein 2
chr10_-_104262426 0.32 ENST00000487599.1
 ACTR1A
 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr20_-_10654639 0.32 ENST00000254958.5
 JAG1
 jagged 1
chr12_+_113659234 0.30 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
 TPCN1
 two pore segment channel 1
chr11_-_66115032 0.29 ENST00000311181.4
 B3GNT1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr11_-_46940074 0.27 ENST00000378623.1
ENST00000534404.1
 LRP4
 low density lipoprotein receptor-related protein 4
chr8_-_67579418 0.27 ENST00000310421.4
 VCPIP1
 valosin containing protein (p97)/p47 complex interacting protein 1
chr17_+_46908350 0.26 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
 CALCOCO2
 calcium binding and coiled-coil domain 2
chr5_+_14143728 0.25 ENST00000344204.4
ENST00000537187.1
 TRIO
 trio Rho guanine nucleotide exchange factor
chr9_-_107690420 0.25 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
 ABCA1
 ATP-binding cassette, sub-family A (ABC1), member 1
chr7_-_120498357 0.25 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
 TSPAN12
 tetraspanin 12
chr9_-_23821273 0.25 ENST00000380110.4
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr10_+_1095416 0.24 ENST00000358220.1
 WDR37
 WD repeat domain 37
chr10_-_3827417 0.24 ENST00000497571.1
ENST00000542957.1
 KLF6
 Kruppel-like factor 6
chr2_-_240322643 0.24 ENST00000345617.3
 HDAC4
 histone deacetylase 4
chr17_-_58603568 0.23 ENST00000083182.3
 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr6_-_108395907 0.22 ENST00000193322.3
 OSTM1
 osteopetrosis associated transmembrane protein 1
chr21_-_15755446 0.22 ENST00000544452.1
ENST00000285667.3
 HSPA13
 heat shock protein 70kDa family, member 13
chr17_-_4167142 0.21 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
 ANKFY1
 ankyrin repeat and FYVE domain containing 1
chr14_+_69865401 0.21 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
 SLC39A9
 solute carrier family 39, member 9
chr11_+_9406169 0.21 ENST00000379719.3
ENST00000527431.1
 IPO7
 importin 7
chr6_+_158733692 0.20 ENST00000367094.2
ENST00000367097.3
 TULP4
 tubby like protein 4
chr3_+_134204881 0.20 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
 CEP63
 centrosomal protein 63kDa
chr5_+_65222299 0.20 ENST00000284037.5
 ERBB2IP
 erbb2 interacting protein
chr7_-_79082867 0.20 ENST00000419488.1
ENST00000354212.4
 MAGI2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
chr14_+_57046500 0.19 ENST00000261556.6
 TMEM260
 transmembrane protein 260
chr18_-_34409116 0.18 ENST00000334295.4
 TPGS2
 tubulin polyglutamylase complex subunit 2
chrX_-_83442915 0.18 ENST00000262752.2
ENST00000543399.1
 RPS6KA6
 ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr20_-_35374456 0.17 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
 NDRG3
 NDRG family member 3
chr12_-_27167233 0.17 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
 TM7SF3
 transmembrane 7 superfamily member 3
chr5_-_141704566 0.17 ENST00000344120.4
ENST00000434127.2
 SPRY4
 sprouty homolog 4 (Drosophila)
chr10_+_126490354 0.17 ENST00000298492.5
 FAM175B
 family with sequence similarity 175, member B
chr9_-_99801592 0.16 ENST00000259470.5
 CTSV
 cathepsin V
chr17_-_37844267 0.16 ENST00000579146.1
ENST00000378011.4
ENST00000429199.2
ENST00000300658.4
 PGAP3
 post-GPI attachment to proteins 3
chr10_+_70091812 0.15 ENST00000265866.7
 HNRNPH3
 heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr3_+_15468862 0.15 ENST00000396842.2
 EAF1
 ELL associated factor 1
chr1_+_151584544 0.15 ENST00000458013.2
ENST00000368843.3
 SNX27
 sorting nexin family member 27
chr7_-_42276612 0.14 ENST00000395925.3
ENST00000437480.1
 GLI3
 GLI family zinc finger 3
chr12_+_107168342 0.14 ENST00000392837.4
 RIC8B
 RIC8 guanine nucleotide exchange factor B
chr1_-_205719295 0.13 ENST00000367142.4
 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
chr20_+_6748311 0.13 ENST00000378827.4
 BMP2
 bone morphogenetic protein 2
chr15_+_91427642 0.13 ENST00000328850.3
ENST00000414248.2
 FES
 feline sarcoma oncogene
chr3_+_139654018 0.13 ENST00000458420.3
 CLSTN2
 calsyntenin 2
chr10_+_104535994 0.12 ENST00000369889.4
 WBP1L
 WW domain binding protein 1-like
chr3_-_52713729 0.12 ENST00000296302.7
ENST00000356770.4
ENST00000337303.4
ENST00000409057.1
ENST00000410007.1
ENST00000409114.3
ENST00000409767.1
ENST00000423351.1
 PBRM1
 polybromo 1
chr17_-_53499310 0.12 ENST00000262065.3
 MMD
 monocyte to macrophage differentiation-associated
chr2_-_178128528 0.11 ENST00000397063.4
ENST00000421929.1
 NFE2L2
 nuclear factor, erythroid 2-like 2
chr6_+_21593972 0.10 ENST00000244745.1
ENST00000543472.1
 SOX4
 SRY (sex determining region Y)-box 4
chr1_+_25664408 0.09 ENST00000374358.4
 TMEM50A
 transmembrane protein 50A
chr14_+_96000930 0.08 ENST00000331334.4
 GLRX5
 glutaredoxin 5
chr17_+_36508111 0.07 ENST00000331159.5
ENST00000577233.1
 SOCS7
 suppressor of cytokine signaling 7
chr1_+_161736072 0.07 ENST00000367942.3
 ATF6
 activating transcription factor 6
chr15_+_91073111 0.07 ENST00000420329.2
 CRTC3
 CREB regulated transcription coactivator 3
chr16_-_2264779 0.07 ENST00000333503.7
 PGP
 phosphoglycolate phosphatase
chr12_-_56583332 0.06 ENST00000347471.4
ENST00000267064.4
ENST00000394023.3
 SMARCC2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr14_-_74485960 0.05 ENST00000556242.1
ENST00000334696.6
 ENTPD5
 ectonucleoside triphosphate diphosphohydrolase 5
chrX_-_20284958 0.05 ENST00000379565.3
 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_52870227 0.04 ENST00000257181.9
 PRPF38A
 pre-mRNA processing factor 38A
chr3_+_32147997 0.04 ENST00000282541.5
 GPD1L
 glycerol-3-phosphate dehydrogenase 1-like
chrX_+_133507327 0.04 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
 PHF6
 PHD finger protein 6
chr17_+_4710391 0.04 ENST00000263088.6
ENST00000572940.1
 PLD2
 phospholipase D2
chr16_+_69599861 0.04 ENST00000354436.2
 NFAT5
 nuclear factor of activated T-cells 5, tonicity-responsive
chr20_+_1099233 0.03 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
 PSMF1
 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr15_-_34502278 0.03 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
 KATNBL1
 katanin p80 subunit B-like 1
chr15_-_42264702 0.03 ENST00000220325.4
 EHD4
 EH-domain containing 4
chr19_+_9945962 0.02 ENST00000587625.1
ENST00000247970.4
ENST00000588695.1
 PIN1
 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
chr1_-_202858227 0.02 ENST00000367262.3
 RABIF
 RAB interacting factor
chr18_+_32073253 0.02 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
 DTNA
 dystrobrevin, alpha
chr1_-_109825719 0.02 ENST00000369904.3
ENST00000369903.2
ENST00000429031.1
ENST00000418914.2
ENST00000409267.1
 PSRC1
 proline/serine-rich coiled-coil 1
chr3_+_150126101 0.02 ENST00000361875.3
ENST00000361136.2
 TSC22D2
 TSC22 domain family, member 2
chr15_+_52043758 0.00 ENST00000249700.4
ENST00000539962.2
 TMOD2
 tropomodulin 2 (neuronal)
chr16_+_30710462 0.00 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
 SRCAP
 Snf2-related CREBBP activator protein

Gene Ontology Analysis

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0043260 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2 1.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.6 GO:1903349 omegasome membrane(GO:1903349)
0.2 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 3.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.3 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.4 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.8 GO:0097227 sperm annulus(GO:0097227)
0.1 0.3 GO:0002177 manchette(GO:0002177)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 1.7 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.5 1.5 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.5 1.4 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.5 2.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.3 1.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.3 0.8 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.7 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.2 1.2 GO:1901096 regulation of autophagosome maturation(GO:1901096) positive regulation of autophagosome maturation(GO:1901098)
0.2 1.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.6 GO:0070428 negative regulation of interleukin-23 production(GO:0032707) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.2 1.9 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 1.5 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 0.5 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.2 0.5 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.2 1.1 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.2 1.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.1 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.1 0.9 GO:0051414 response to cortisol(GO:0051414)
0.1 0.5 GO:0035973 aggrephagy(GO:0035973)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.8 GO:0071692 sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 1.6 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.3 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.5 GO:0032328 alanine transport(GO:0032328)
0.1 0.9 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.4 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0003289 atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 1.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.3 GO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740)
0.0 0.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 1.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0030098 lymphocyte differentiation(GO:0030098) B cell differentiation(GO:0030183)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 1.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0051642 centrosome localization(GO:0051642)
0.0 0.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 1.5 GO:0030516 regulation of axon extension(GO:0030516)
0.0 1.0 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.9 GO:1900046 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.4 GO:0014002 astrocyte development(GO:0014002)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.5 1.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 2.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.4 3.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 1.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.6 GO:0042301 phosphate ion binding(GO:0042301)
0.1 1.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.0 1.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.1 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 3.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 5.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta