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ENCODE cell lines, expression (Ernst 2011)

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Results for ALX1_ARX

Z-value: 0.47

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Transcription factors associated with ALX1_ARX

Gene Symbol Gene ID Gene Info
ALX1
ENSG00000180318.3 ALX1
ARX
ENSG00000004848.6 ARX

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX1hg19_v2_chr12_+_85673868_856738850.116.9e-01Click!

Activity profile of ALX1_ARX motif

Sorted Z-values of ALX1_ARX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ALX1_ARX

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_92371839 2.19 ENST00000370399.2
 TGFBR3
 transforming growth factor, beta receptor III
chrX_-_11284095 1.16 ENST00000303025.6
ENST00000534860.1
 ARHGAP6
 Rho GTPase activating protein 6
chr6_+_34204642 0.89 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1
 high mobility group AT-hook 1
chr17_-_39023462 0.80 ENST00000251643.4
 KRT12
 keratin 12
chr6_+_26199737 0.68 ENST00000359985.1
 HIST1H2BF
 histone cluster 1, H2bf
chr3_-_141747950 0.65 ENST00000497579.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr14_+_24099318 0.65 ENST00000432832.2
 DHRS2
 dehydrogenase/reductase (SDR family) member 2
chr3_-_157824292 0.62 ENST00000483851.2
 SHOX2
 short stature homeobox 2
chr4_-_100356291 0.59 ENST00000476959.1
ENST00000482593.1
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr16_+_68119247 0.58 ENST00000575270.1
 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_55496174 0.57 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
 MTIF2
 mitochondrial translational initiation factor 2
chr3_-_33759699 0.55 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
 CLASP2
 cytoplasmic linker associated protein 2
chr8_-_57123815 0.52 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
 PLAG1
 pleiomorphic adenoma gene 1
chr8_-_91095099 0.52 ENST00000265431.3
 CALB1
 calbindin 1, 28kDa
chr6_-_26199499 0.51 ENST00000377831.5
 HIST1H3D
 histone cluster 1, H3d
chr6_-_41039567 0.45 ENST00000468811.1
 OARD1
 O-acyl-ADP-ribose deacylase 1
chr4_-_100356551 0.43 ENST00000209665.4
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_141747439 0.42 ENST00000467667.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr8_+_107738240 0.41 ENST00000449762.2
ENST00000297447.6
 OXR1
 oxidation resistance 1
chr16_+_68119324 0.37 ENST00000349223.5
 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr16_+_68119440 0.36 ENST00000346183.3
ENST00000329524.4
 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr7_-_140482926 0.36 ENST00000496384.2
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chrX_+_77166172 0.36 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr6_-_26199471 0.35 ENST00000341023.1
 HIST1H2AD
 histone cluster 1, H2ad
chr8_-_102803163 0.35 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
 NCALD
 neurocalcin delta
chr1_+_206557366 0.34 ENST00000414007.1
ENST00000419187.2
 SRGAP2
 SLIT-ROBO Rho GTPase activating protein 2
chr3_-_141747459 0.34 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
 TFDP2
 transcription factor Dp-2 (E2F dimerization partner 2)
chr8_-_86253888 0.34 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
 CA1
 carbonic anhydrase I
chr6_-_99797522 0.31 ENST00000389677.5
 FAXC
 failed axon connections homolog (Drosophila)
chr9_+_135854091 0.27 ENST00000450530.1
ENST00000534944.1
 GFI1B
 growth factor independent 1B transcription repressor
chr1_+_50569575 0.25 ENST00000371827.1
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr17_+_39240459 0.25 ENST00000391417.4
 KRTAP4-7
 keratin associated protein 4-7
chr12_-_23737534 0.24 ENST00000396007.2
 SOX5
 SRY (sex determining region Y)-box 5
chr16_+_1728257 0.22 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
 HN1L
 hematological and neurological expressed 1-like
chr2_+_58655461 0.21 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
 AC007092.1
 long intergenic non-protein coding RNA 1122
chr2_+_196313239 0.21 ENST00000413290.1
 AC064834.1
 AC064834.1
chr1_-_200379129 0.21 ENST00000367353.1
 ZNF281
 zinc finger protein 281
chr17_+_7155819 0.20 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
 ELP5
 elongator acetyltransferase complex subunit 5
chr2_+_162272605 0.20 ENST00000389554.3
 TBR1
 T-box, brain, 1
chr12_-_118628350 0.20 ENST00000537952.1
ENST00000537822.1
 TAOK3
 TAO kinase 3
chr2_-_145278475 0.20 ENST00000558170.2
 ZEB2
 zinc finger E-box binding homeobox 2
chr2_-_70529180 0.20 ENST00000450256.1
ENST00000037869.3
 FAM136A
 family with sequence similarity 136, member A
chr6_-_150067696 0.20 ENST00000340413.2
ENST00000367403.3
 NUP43
 nucleoporin 43kDa
chr12_-_118797475 0.19 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
 TAOK3
 TAO kinase 3
chr6_+_27791862 0.19 ENST00000355057.1
 HIST1H4J
 histone cluster 1, H4j
chr6_-_32908792 0.18 ENST00000418107.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr4_-_87028478 0.18 ENST00000515400.1
ENST00000395157.3
 MAPK10
 mitogen-activated protein kinase 10
chr4_-_176733897 0.18 ENST00000393658.2
 GPM6A
 glycoprotein M6A
chrX_-_138724994 0.18 ENST00000536274.1
 MCF2
 MCF.2 cell line derived transforming sequence
chr19_-_6393216 0.17 ENST00000595047.1
 GTF2F1
 general transcription factor IIF, polypeptide 1, 74kDa
chr12_+_122241928 0.17 ENST00000604567.1
ENST00000542440.1
 SETD1B
 SET domain containing 1B
chr17_+_71228537 0.17 ENST00000577615.1
ENST00000585109.1
 C17orf80
 chromosome 17 open reading frame 80
chrX_+_119737806 0.16 ENST00000371317.5
 MCTS1
 malignant T cell amplified sequence 1
chr10_+_18689637 0.15 ENST00000377315.4
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr19_-_6393465 0.14 ENST00000394456.5
 GTF2F1
 general transcription factor IIF, polypeptide 1, 74kDa
chr17_+_71228740 0.14 ENST00000268942.8
ENST00000359042.2
 C17orf80
 chromosome 17 open reading frame 80
chr14_-_38064198 0.14 ENST00000250448.2
 FOXA1
 forkhead box A1
chr11_+_128563652 0.13 ENST00000527786.2
 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
chr7_+_136553370 0.13 ENST00000445907.2
 CHRM2
 cholinergic receptor, muscarinic 2
chr6_-_32908765 0.13 ENST00000416244.2
 HLA-DMB
 major histocompatibility complex, class II, DM beta
chr1_+_186265399 0.13 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
 PRG4
 proteoglycan 4
chr14_+_95078714 0.12 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
 SERPINA3
 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr6_-_111804905 0.12 ENST00000358835.3
ENST00000435970.1
 REV3L
 REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr15_+_57511609 0.12 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
 TCF12
 transcription factor 12
chr9_-_21202204 0.12 ENST00000239347.3
 IFNA7
 interferon, alpha 7
chr3_+_190105909 0.12 ENST00000456423.1
 CLDN16
 claudin 16
chr10_+_35464513 0.12 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
 CREM
 cAMP responsive element modulator
chr3_+_12329397 0.12 ENST00000397015.2
 PPARG
 peroxisome proliferator-activated receptor gamma
chr2_+_185463093 0.12 ENST00000302277.6
 ZNF804A
 zinc finger protein 804A
chr5_-_55412774 0.12 ENST00000434982.2
 ANKRD55
 ankyrin repeat domain 55
chr9_+_42671887 0.12 ENST00000456520.1
ENST00000377391.3
 CBWD7
 COBW domain containing 7
chr1_-_110155671 0.12 ENST00000351050.3
 GNAT2
 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr12_-_112123524 0.11 ENST00000327551.6
 BRAP
 BRCA1 associated protein
chrX_+_149887090 0.11 ENST00000538506.1
 MTMR1
 myotubularin related protein 1
chr3_+_39424828 0.11 ENST00000273158.4
ENST00000431510.1
 SLC25A38
 solute carrier family 25, member 38
chr1_+_62439037 0.11 ENST00000545929.1
 INADL
 InaD-like (Drosophila)
chr3_+_12329358 0.11 ENST00000309576.6
 PPARG
 peroxisome proliferator-activated receptor gamma
chr4_+_113568207 0.11 ENST00000511529.1
 LARP7
 La ribonucleoprotein domain family, member 7
chr11_+_95523621 0.11 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
 CEP57
 centrosomal protein 57kDa
chr2_+_44001172 0.11 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
 DYNC2LI1
 dynein, cytoplasmic 2, light intermediate chain 1
chr3_-_87325612 0.11 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
 POU1F1
 POU class 1 homeobox 1
chr17_+_71228793 0.10 ENST00000426147.2
 C17orf80
 chromosome 17 open reading frame 80
chr11_+_120973375 0.10 ENST00000264037.2
 TECTA
 tectorin alpha
chr2_+_152214098 0.10 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr8_+_26150628 0.10 ENST00000523925.1
ENST00000315985.7
 PPP2R2A
 protein phosphatase 2, regulatory subunit B, alpha
chr5_+_36152179 0.10 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr5_-_115872142 0.09 ENST00000510263.1
 SEMA6A
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_200379180 0.09 ENST00000294740.3
 ZNF281
 zinc finger protein 281
chr1_+_52682052 0.09 ENST00000371591.1
 ZFYVE9
 zinc finger, FYVE domain containing 9
chr8_-_61880248 0.09 ENST00000525556.1
 AC022182.3
 AC022182.3
chr2_+_228678550 0.09 ENST00000409189.3
ENST00000358813.4
 CCL20
 chemokine (C-C motif) ligand 20
chr17_-_39623681 0.09 ENST00000225899.3
 KRT32
 keratin 32
chr14_-_36988882 0.09 ENST00000498187.2
 NKX2-1
 NK2 homeobox 1
chr7_+_93535817 0.08 ENST00000248572.5
 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_-_130465604 0.08 ENST00000356763.3
 PIK3R4
 phosphoinositide-3-kinase, regulatory subunit 4
chr11_-_82708435 0.08 ENST00000525117.1
ENST00000532548.1
 RAB30
 RAB30, member RAS oncogene family
chr5_+_145826867 0.08 ENST00000296702.5
ENST00000394421.2
 TCERG1
 transcription elongation regulator 1
chr2_-_166930131 0.08 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
 SCN1A
 sodium channel, voltage-gated, type I, alpha subunit
chr3_+_140660743 0.07 ENST00000453248.2
 SLC25A36
 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr7_-_25268104 0.07 ENST00000222674.2
 NPVF
 neuropeptide VF precursor
chr1_+_92632542 0.07 ENST00000409154.4
ENST00000370378.4
 KIAA1107
 KIAA1107
chr6_+_31895254 0.07 ENST00000299367.5
ENST00000442278.2
 C2
 complement component 2
chr2_+_65215604 0.07 ENST00000531327.1
 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_+_55980331 0.07 ENST00000429591.2
 ZNF713
 zinc finger protein 713
chr5_+_40909354 0.07 ENST00000313164.9
 C7
 complement component 7
chr6_-_27835357 0.07 ENST00000331442.3
 HIST1H1B
 histone cluster 1, H1b
chr6_-_133055815 0.07 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
 VNN3
 vanin 3
chr15_+_44092784 0.06 ENST00000458412.1
 HYPK
 huntingtin interacting protein K
chr10_+_97803151 0.06 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
 CCNJ
 cyclin J
chr12_-_53601000 0.06 ENST00000338737.4
ENST00000549086.2
 ITGB7
 integrin, beta 7
chr3_-_87325728 0.06 ENST00000350375.2
 POU1F1
 POU class 1 homeobox 1
chr5_+_59783941 0.06 ENST00000506884.1
ENST00000504876.2
 PART1
 prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_104615595 0.06 ENST00000418362.1
 RP11-364B6.1
 RP11-364B6.1
chr4_+_118955500 0.06 ENST00000296499.5
 NDST3
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr8_+_38677850 0.06 ENST00000518809.1
ENST00000520611.1
 TACC1
 transforming, acidic coiled-coil containing protein 1
chr11_-_8964580 0.06 ENST00000325884.1
 ASCL3
 achaete-scute family bHLH transcription factor 3
chr12_-_43833515 0.05 ENST00000549670.1
ENST00000395541.2
 ADAMTS20
 ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr2_+_75873902 0.05 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
 MRPL19
 mitochondrial ribosomal protein L19
chr21_-_31588365 0.05 ENST00000399899.1
 CLDN8
 claudin 8
chr12_-_10324716 0.05 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
 OLR1
 oxidized low density lipoprotein (lectin-like) receptor 1
chr12_-_53601055 0.05 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
 ITGB7
 integrin, beta 7
chr10_-_102989551 0.05 ENST00000370193.2
 LBX1
 ladybird homeobox 1
chr1_+_183774240 0.05 ENST00000360851.3
 RGL1
 ral guanine nucleotide dissociation stimulator-like 1
chr2_+_54683419 0.05 ENST00000356805.4
 SPTBN1
 spectrin, beta, non-erythrocytic 1
chr3_+_140660634 0.05 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
 SLC25A36
 solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr16_+_24549014 0.05 ENST00000564314.1
ENST00000567686.1
 RBBP6
 retinoblastoma binding protein 6
chr5_+_137203557 0.05 ENST00000515645.1
 MYOT
 myotilin
chr4_+_88571429 0.04 ENST00000339673.6
ENST00000282479.7
 DMP1
 dentin matrix acidic phosphoprotein 1
chr3_-_101039402 0.04 ENST00000193391.7
 IMPG2
 interphotoreceptor matrix proteoglycan 2
chr10_-_29923893 0.04 ENST00000355867.4
 SVIL
 supervillin
chr4_+_76649797 0.04 ENST00000538159.1
ENST00000514213.2
 USO1
 USO1 vesicle transport factor
chr2_-_145275228 0.04 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
 ZEB2
 zinc finger E-box binding homeobox 2
chr12_+_59989918 0.04 ENST00000547379.1
ENST00000549465.1
 SLC16A7
 solute carrier family 16 (monocarboxylate transporter), member 7
chr1_+_154401791 0.04 ENST00000476006.1
 IL6R
 interleukin 6 receptor
chr18_-_13915530 0.04 ENST00000327606.3
 MC2R
 melanocortin 2 receptor (adrenocorticotropic hormone)
chr2_+_101437487 0.04 ENST00000427413.1
ENST00000542504.1
 NPAS2
 neuronal PAS domain protein 2
chr1_+_180601139 0.03 ENST00000367590.4
ENST00000367589.3
 XPR1
 xenotropic and polytropic retrovirus receptor 1
chr2_+_191334212 0.03 ENST00000444317.1
ENST00000535751.1
 MFSD6
 major facilitator superfamily domain containing 6
chr3_-_167191814 0.03 ENST00000466903.1
ENST00000264677.4
 SERPINI2
 serpin peptidase inhibitor, clade I (pancpin), member 2
chr5_-_59783882 0.03 ENST00000505507.2
ENST00000502484.2
 PDE4D
 phosphodiesterase 4D, cAMP-specific
chr3_-_45837959 0.03 ENST00000353278.4
ENST00000456124.2
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chrX_-_15619076 0.03 ENST00000252519.3
 ACE2
 angiotensin I converting enzyme 2
chr3_-_45838011 0.03 ENST00000358525.4
ENST00000413781.1
 SLC6A20
 solute carrier family 6 (proline IMINO transporter), member 20
chr4_+_155484155 0.03 ENST00000509493.1
 FGB
 fibrinogen beta chain
chr2_+_161993465 0.03 ENST00000457476.1
 TANK
 TRAF family member-associated NFKB activator
chr10_-_112064665 0.03 ENST00000369603.5
 SMNDC1
 survival motor neuron domain containing 1
chr1_-_13390765 0.02 ENST00000357367.2
 PRAMEF8
 PRAME family member 8
chr5_+_36152091 0.02 ENST00000274254.5
 SKP2
 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr5_-_39270725 0.02 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
 FYB
 FYN binding protein
chr8_-_6420930 0.02 ENST00000325203.5
 ANGPT2
 angiopoietin 2
chr3_+_121774202 0.02 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
 CD86
 CD86 molecule
chr2_+_119699742 0.02 ENST00000327097.4
 MARCO
 macrophage receptor with collagenous structure
chr4_+_156824840 0.02 ENST00000536354.2
 TDO2
 tryptophan 2,3-dioxygenase
chr11_-_58499434 0.02 ENST00000344743.3
ENST00000278400.3
 GLYAT
 glycine-N-acyltransferase
chr12_+_122688090 0.02 ENST00000324189.4
ENST00000546192.1
 B3GNT4
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_-_195310802 0.01 ENST00000421243.1
ENST00000453131.1
 APOD
 apolipoprotein D
chr1_+_158323755 0.01 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
 CD1E
 CD1e molecule
chr13_-_47471155 0.01 ENST00000543956.1
ENST00000542664.1
 HTR2A
 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr12_-_118796910 0.01 ENST00000541186.1
ENST00000539872.1
 TAOK3
 TAO kinase 3
chr18_+_66465302 0.01 ENST00000360242.5
ENST00000358653.5
 CCDC102B
 coiled-coil domain containing 102B
chr12_+_12878829 0.01 ENST00000326765.6
 APOLD1
 apolipoprotein L domain containing 1
chr4_-_174320687 0.01 ENST00000296506.3
 SCRG1
 stimulator of chondrogenesis 1
chr4_+_155484103 0.01 ENST00000302068.4
 FGB
 fibrinogen beta chain
chr5_-_160279207 0.01 ENST00000327245.5
 ATP10B
 ATPase, class V, type 10B
chr12_-_67197760 0.01 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
 GRIP1
 glutamate receptor interacting protein 1
chr3_+_40518599 0.01 ENST00000314686.5
ENST00000447116.2
ENST00000429348.2
ENST00000456778.1
 ZNF619
 zinc finger protein 619
chr7_+_107224364 0.00 ENST00000491150.1
 BCAP29
 B-cell receptor-associated protein 29
chr15_+_66874502 0.00 ENST00000558797.1
 RP11-321F6.1
 HCG2003567; Uncharacterized protein
chr6_+_45296391 0.00 ENST00000371436.6
ENST00000576263.1
 RUNX2
 runt-related transcription factor 2
chrX_+_16668278 0.00 ENST00000380200.3
 S100G
 S100 calcium binding protein G
chr3_-_98241760 0.00 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
 CLDND1
 claudin domain containing 1
chr5_-_134735568 0.00 ENST00000510038.1
ENST00000304332.4
 H2AFY
 H2A histone family, member Y
chr5_-_27038683 0.00 ENST00000511822.1
ENST00000231021.4
 CDH9
 cadherin 9, type 2 (T1-cadherin)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035276 aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276)
0.2 2.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.7 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.4 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 1.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.7 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 1.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.3 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.7 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.0 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID IL4 2PATHWAY IL4-mediated signaling events