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ENCODE cell lines, expression (Ernst 2011)

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Results for ATF6

Z-value: 1.14

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Transcription factors associated with ATF6

Gene Symbol Gene ID Gene Info
ATF6
ENSG00000118217.5 ATF6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_1617360930.097.5e-01Click!

Activity profile of ATF6 motif

Sorted Z-values of ATF6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chrX_-_100914781 5.01 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
 ARMCX2
 armadillo repeat containing, X-linked 2
chr6_+_116692102 3.60 ENST00000359564.2
 DSE
 dermatan sulfate epimerase
chr11_-_35547572 2.59 ENST00000378880.2
 PAMR1
 peptidase domain containing associated with muscle regeneration 1
chr11_-_35547151 2.34 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
 PAMR1
 peptidase domain containing associated with muscle regeneration 1
chr12_-_106641728 2.28 ENST00000378026.4
 CKAP4
 cytoskeleton-associated protein 4
chrX_+_102631844 2.26 ENST00000372634.1
ENST00000299872.7
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102631248 2.16 ENST00000361298.4
ENST00000372645.3
ENST00000372635.1
 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
chr14_+_96505659 2.05 ENST00000555004.1
 C14orf132
 chromosome 14 open reading frame 132
chr19_+_16187085 1.90 ENST00000300933.4
 TPM4
 tropomyosin 4
chr9_+_112542572 1.89 ENST00000374530.3
 PALM2-AKAP2
 PALM2-AKAP2 readthrough
chr9_+_36036430 1.78 ENST00000377966.3
 RECK
 reversion-inducing-cysteine-rich protein with kazal motifs
chr19_+_16186903 1.73 ENST00000588507.1
 TPM4
 tropomyosin 4
chr8_+_94929077 1.54 ENST00000297598.4
ENST00000520614.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr9_-_79520989 1.52 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
 PRUNE2
 prune homolog 2 (Drosophila)
chr8_+_94929168 1.52 ENST00000518107.1
ENST00000396200.3
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_94929110 1.47 ENST00000520728.1
 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_19157248 1.42 ENST00000242261.5
 TWIST1
 twist family bHLH transcription factor 1
chr11_+_32112431 1.40 ENST00000054950.3
 RCN1
 reticulocalbin 1, EF-hand calcium binding domain
chr21_+_38445539 1.38 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
 TTC3
 tetratricopeptide repeat domain 3
chr22_+_38864041 1.31 ENST00000216014.4
ENST00000409006.3
 KDELR3
 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr13_-_49107303 1.31 ENST00000344532.3
 RCBTB2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr8_-_98290087 1.31 ENST00000322128.3
 TSPYL5
 TSPY-like 5
chr19_+_49458107 1.28 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
 BAX
 BCL2-associated X protein
chr20_-_34042558 1.22 ENST00000374372.1
 GDF5
 growth differentiation factor 5
chr15_+_67420441 1.20 ENST00000558894.1
 SMAD3
 SMAD family member 3
chr5_-_72744336 1.18 ENST00000499003.3
 FOXD1
 forkhead box D1
chrX_-_100872911 1.17 ENST00000361910.4
ENST00000539247.1
ENST00000538627.1
 ARMCX6
 armadillo repeat containing, X-linked 6
chr3_+_45067659 1.11 ENST00000296130.4
 CLEC3B
 C-type lectin domain family 3, member B
chr7_-_86849883 1.07 ENST00000433078.1
 TMEM243
 transmembrane protein 243, mitochondrial
chr16_-_66959429 0.98 ENST00000420652.1
ENST00000299759.6
 RRAD
 Ras-related associated with diabetes
chr5_-_131562935 0.98 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
 P4HA2
 prolyl 4-hydroxylase, alpha polypeptide II
chr3_+_33318914 0.97 ENST00000484457.1
ENST00000538892.1
ENST00000538181.1
ENST00000446237.3
ENST00000507198.1
 FBXL2
 F-box and leucine-rich repeat protein 2
chr4_-_119757239 0.97 ENST00000280551.6
 SEC24D
 SEC24 family member D
chr4_-_111544254 0.97 ENST00000306732.3
 PITX2
 paired-like homeodomain 2
chr10_-_118032979 0.97 ENST00000355422.6
 GFRA1
 GDNF family receptor alpha 1
chr1_-_94050668 0.97 ENST00000539242.1
 BCAR3
 breast cancer anti-estrogen resistance 3
chr18_+_56530794 0.92 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
 ZNF532
 zinc finger protein 532
chr3_+_50284321 0.90 ENST00000451956.1
 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_+_100211412 0.89 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
 TMEM45A
 transmembrane protein 45A
chr1_+_19970657 0.84 ENST00000375136.3
 NBL1
 neuroblastoma 1, DAN family BMP antagonist
chr1_-_152009460 0.84 ENST00000271638.2
 S100A11
 S100 calcium binding protein A11
chr7_+_128470431 0.83 ENST00000325888.8
ENST00000346177.6
 FLNC
 filamin C, gamma
chr4_+_668348 0.83 ENST00000511290.1
 MYL5
 myosin, light chain 5, regulatory
chr7_+_100464760 0.81 ENST00000200457.4
 TRIP6
 thyroid hormone receptor interactor 6
chr6_-_128841503 0.81 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
 PTPRK
 protein tyrosine phosphatase, receptor type, K
chr1_+_87170577 0.79 ENST00000482504.1
 SH3GLB1
 SH3-domain GRB2-like endophilin B1
chr1_+_19970797 0.78 ENST00000548815.1
 NBL1
 neuroblastoma 1, DAN family BMP antagonist
chr17_-_39968406 0.76 ENST00000393928.1
 LEPREL4
 leprecan-like 4
chr19_-_10121144 0.76 ENST00000264828.3
 COL5A3
 collagen, type V, alpha 3
chr14_+_64970662 0.76 ENST00000556965.1
ENST00000554015.1
 ZBTB1
 zinc finger and BTB domain containing 1
chr9_-_89562104 0.76 ENST00000298743.7
 GAS1
 growth arrest-specific 1
chr5_+_34656569 0.75 ENST00000428746.2
 RAI14
 retinoic acid induced 14
chr5_+_34656331 0.73 ENST00000265109.3
 RAI14
 retinoic acid induced 14
chr12_-_102455902 0.73 ENST00000240079.6
 CCDC53
 coiled-coil domain containing 53
chr11_+_1891380 0.73 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
 LSP1
 lymphocyte-specific protein 1
chr12_-_102455846 0.73 ENST00000545679.1
 CCDC53
 coiled-coil domain containing 53
chr15_-_40213080 0.72 ENST00000561100.1
 GPR176
 G protein-coupled receptor 176
chr7_+_128379346 0.71 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
 CALU
 calumenin
chr1_-_20812690 0.70 ENST00000375078.3
 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
chr8_-_57906362 0.70 ENST00000262644.4
 IMPAD1
 inositol monophosphatase domain containing 1
chr14_+_50087468 0.70 ENST00000305386.2
 MGAT2
 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr13_-_36920615 0.70 ENST00000494062.2
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr2_+_242254679 0.69 ENST00000428282.1
ENST00000360051.3
 SEPT2
 septin 2
chrX_+_48433326 0.69 ENST00000376755.1
 RBM3
 RNA binding motif (RNP1, RRM) protein 3
chr3_-_57583185 0.67 ENST00000463880.1
 ARF4
 ADP-ribosylation factor 4
chr13_-_36920872 0.65 ENST00000451493.1
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr13_-_36920420 0.64 ENST00000438666.2
 SPG20
 spastic paraplegia 20 (Troyer syndrome)
chr17_-_66951474 0.64 ENST00000269080.2
 ABCA8
 ATP-binding cassette, sub-family A (ABC1), member 8
chr3_+_129158926 0.64 ENST00000347300.2
ENST00000296266.3
 IFT122
 intraflagellar transport 122 homolog (Chlamydomonas)
chr7_-_37956409 0.64 ENST00000436072.2
 SFRP4
 secreted frizzled-related protein 4
chr2_-_242255117 0.60 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
 HDLBP
 high density lipoprotein binding protein
chr7_+_128379449 0.60 ENST00000479257.1
 CALU
 calumenin
chr10_+_112257596 0.59 ENST00000369583.3
 DUSP5
 dual specificity phosphatase 5
chr3_-_57583130 0.58 ENST00000303436.6
 ARF4
 ADP-ribosylation factor 4
chr12_-_56123444 0.58 ENST00000546457.1
ENST00000549117.1
 CD63
 CD63 molecule
chr3_-_121468513 0.57 ENST00000494517.1
ENST00000393667.3
 GOLGB1
 golgin B1
chr3_-_57583052 0.57 ENST00000496292.1
ENST00000489843.1
 ARF4
 ADP-ribosylation factor 4
chr3_+_148709128 0.57 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
 GYG1
 glycogenin 1
chr16_-_88923285 0.57 ENST00000542788.1
ENST00000569433.1
ENST00000268695.5
ENST00000568311.1
 GALNS
 galactosamine (N-acetyl)-6-sulfate sulfatase
chr5_-_131563501 0.56 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
 P4HA2
 prolyl 4-hydroxylase, alpha polypeptide II
chr3_+_158519654 0.56 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
 MFSD1
 major facilitator superfamily domain containing 1
chr1_-_161993616 0.56 ENST00000294794.3
 OLFML2B
 olfactomedin-like 2B
chr2_-_55276320 0.55 ENST00000357376.3
 RTN4
 reticulon 4
chr3_+_133292574 0.54 ENST00000264993.3
 CDV3
 CDV3 homolog (mouse)
chr2_-_98612350 0.54 ENST00000186436.5
 TMEM131
 transmembrane protein 131
chr9_+_114393634 0.54 ENST00000556107.1
ENST00000374294.3
 DNAJC25
DNAJC25-GNG10
 DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr3_+_129159039 0.54 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
 IFT122
 intraflagellar transport 122 homolog (Chlamydomonas)
chr3_-_121468602 0.53 ENST00000340645.5
 GOLGB1
 golgin B1
chr2_+_242254507 0.52 ENST00000391973.2
 SEPT2
 septin 2
chr2_-_197036289 0.51 ENST00000263955.4
 STK17B
 serine/threonine kinase 17b
chr17_-_39968855 0.51 ENST00000355468.3
ENST00000590496.1
 LEPREL4
 leprecan-like 4
chr2_-_237076992 0.50 ENST00000306318.4
 GBX2
 gastrulation brain homeobox 2
chr17_-_19771216 0.50 ENST00000395544.4
 ULK2
 unc-51 like autophagy activating kinase 2
chr14_-_23822080 0.48 ENST00000397267.1
ENST00000354772.3
 SLC22A17
 solute carrier family 22, member 17
chr6_-_90062543 0.48 ENST00000435041.2
 UBE2J1
 ubiquitin-conjugating enzyme E2, J1
chr21_-_38445470 0.47 ENST00000399098.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr13_+_114238997 0.47 ENST00000538138.1
ENST00000375370.5
 TFDP1
 transcription factor Dp-1
chr10_-_74856608 0.46 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
 P4HA1
 prolyl 4-hydroxylase, alpha polypeptide I
chr19_-_48018203 0.44 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
chr14_-_23822061 0.44 ENST00000397260.3
 SLC22A17
 solute carrier family 22, member 17
chr17_+_33914276 0.44 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
 AP2B1
 adaptor-related protein complex 2, beta 1 subunit
chr17_-_57184260 0.43 ENST00000376149.3
ENST00000393066.3
 TRIM37
 tripartite motif containing 37
chr17_+_33914460 0.43 ENST00000537622.2
 AP2B1
 adaptor-related protein complex 2, beta 1 subunit
chr17_-_17875688 0.42 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
 TOM1L2
 target of myb1-like 2 (chicken)
chr2_+_242255297 0.42 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
 SEPT2
 septin 2
chr6_-_86352982 0.42 ENST00000369622.3
 SYNCRIP
 synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_-_125398654 0.42 ENST00000541645.1
ENST00000540351.1
 UBC
 ubiquitin C
chr21_-_38445443 0.42 ENST00000360525.4
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr15_+_23255242 0.41 ENST00000450802.3
 GOLGA8I
 golgin A8 family, member I
chr19_+_13858593 0.41 ENST00000221554.8
 CCDC130
 coiled-coil domain containing 130
chr3_-_156272924 0.41 ENST00000467789.1
ENST00000265044.2
 SSR3
 signal sequence receptor, gamma (translocon-associated protein gamma)
chr6_+_127587755 0.40 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
 RNF146
 ring finger protein 146
chr8_+_22423168 0.40 ENST00000518912.1
ENST00000428103.1
 SORBS3
 sorbin and SH3 domain containing 3
chr17_-_57184064 0.40 ENST00000262294.7
 TRIM37
 tripartite motif containing 37
chr12_+_54378923 0.39 ENST00000303460.4
 HOXC10
 homeobox C10
chr12_+_147052 0.39 ENST00000594563.1
 AC026369.1
 Uncharacterized protein
chr15_+_31619013 0.39 ENST00000307145.3
 KLF13
 Kruppel-like factor 13
chr1_-_160313025 0.38 ENST00000368069.3
ENST00000241704.7
 COPA
 coatomer protein complex, subunit alpha
chr7_+_99699280 0.38 ENST00000421755.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr17_+_18684563 0.37 ENST00000476139.1
 TVP23B
 trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr12_-_125398602 0.37 ENST00000541272.1
ENST00000535131.1
 UBC
 ubiquitin C
chr1_-_32169761 0.36 ENST00000271069.6
 COL16A1
 collagen, type XVI, alpha 1
chrX_+_153672468 0.36 ENST00000393600.3
 FAM50A
 family with sequence similarity 50, member A
chr3_+_184529948 0.36 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
chr7_+_99699179 0.36 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
 AP4M1
 adaptor-related protein complex 4, mu 1 subunit
chr2_-_105946491 0.35 ENST00000393359.2
 TGFBRAP1
 transforming growth factor, beta receptor associated protein 1
chr8_+_142138711 0.35 ENST00000518347.1
ENST00000262585.2
ENST00000424248.1
ENST00000519811.1
ENST00000520986.1
ENST00000523058.1
 DENND3
 DENN/MADD domain containing 3
chr9_-_74980113 0.35 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
 ZFAND5
 zinc finger, AN1-type domain 5
chr17_+_17876127 0.34 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
 LRRC48
 leucine rich repeat containing 48
chr17_+_46048376 0.34 ENST00000338399.4
 CDK5RAP3
 CDK5 regulatory subunit associated protein 3
chr1_-_32169920 0.34 ENST00000373672.3
ENST00000373668.3
 COL16A1
 collagen, type XVI, alpha 1
chr22_-_20850128 0.34 ENST00000328879.4
 KLHL22
 kelch-like family member 22
chr2_-_242254595 0.34 ENST00000441124.1
ENST00000391976.2
 HDLBP
 high density lipoprotein binding protein
chr15_-_43785303 0.33 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
 TP53BP1
 tumor protein p53 binding protein 1
chr1_+_160313062 0.33 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
 NCSTN
 nicastrin
chr1_-_78149041 0.32 ENST00000414381.1
ENST00000370798.1
 ZZZ3
 zinc finger, ZZ-type containing 3
chrX_-_102941596 0.32 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
 MORF4L2
 mortality factor 4 like 2
chr16_-_67514982 0.32 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
 ATP6V0D1
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr11_-_64646086 0.32 ENST00000320631.3
 EHD1
 EH-domain containing 1
chr5_-_94890648 0.31 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
 TTC37
 tetratricopeptide repeat domain 37
chr12_+_54718904 0.30 ENST00000262061.2
ENST00000549043.1
ENST00000552218.1
ENST00000553231.1
ENST00000552362.1
ENST00000455864.2
ENST00000416254.2
ENST00000549116.1
ENST00000551779.1
 COPZ1
 coatomer protein complex, subunit zeta 1
chr17_-_19771242 0.29 ENST00000361658.2
 ULK2
 unc-51 like autophagy activating kinase 2
chr7_-_6523755 0.29 ENST00000436575.1
ENST00000258739.4
 DAGLB
KDELR2
 diacylglycerol lipase, beta
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr14_-_106092403 0.29 ENST00000390543.2
 IGHG4
 immunoglobulin heavy constant gamma 4 (G4m marker)
chr16_-_70719925 0.29 ENST00000338779.6
 MTSS1L
 metastasis suppressor 1-like
chr20_+_34359905 0.29 ENST00000374012.3
ENST00000439301.1
ENST00000339089.6
ENST00000374000.4
 PHF20
 PHD finger protein 20
chr3_+_184529929 0.28 ENST00000287546.4
ENST00000437079.3
 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
chrX_-_153059958 0.28 ENST00000370092.3
ENST00000217901.5
 IDH3G
 isocitrate dehydrogenase 3 (NAD+) gamma
chr21_-_46237959 0.27 ENST00000397898.3
ENST00000411651.2
 SUMO3
 small ubiquitin-like modifier 3
chr14_-_81687575 0.27 ENST00000434192.2
 GTF2A1
 general transcription factor IIA, 1, 19/37kDa
chr12_+_110562135 0.27 ENST00000361948.4
ENST00000552912.1
ENST00000242591.5
ENST00000546374.1
 IFT81
 intraflagellar transport 81 homolog (Chlamydomonas)
chr16_+_19729586 0.26 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
 IQCK
 IQ motif containing K
chr16_-_30366672 0.26 ENST00000305596.3
 CD2BP2
 CD2 (cytoplasmic tail) binding protein 2
chr12_-_49412588 0.26 ENST00000547082.1
ENST00000395170.3
 PRKAG1
 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr17_+_59529743 0.25 ENST00000589003.1
ENST00000393853.4
 TBX4
 T-box 4
chrX_+_100663243 0.25 ENST00000316594.5
 HNRNPH2
 heterogeneous nuclear ribonucleoprotein H2 (H')
chr11_-_14521379 0.25 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
 COPB1
 coatomer protein complex, subunit beta 1
chr1_-_78148324 0.25 ENST00000370801.3
ENST00000433749.1
 ZZZ3
 zinc finger, ZZ-type containing 3
chr11_+_58910295 0.24 ENST00000420244.1
 FAM111A
 family with sequence similarity 111, member A
chr16_-_2827128 0.24 ENST00000494946.2
ENST00000409477.1
ENST00000572954.1
ENST00000262306.7
ENST00000409906.4
 TCEB2
 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
chr1_+_40505891 0.23 ENST00000372797.3
ENST00000372802.1
ENST00000449311.1
 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
chr12_-_49412541 0.23 ENST00000547306.1
ENST00000548857.1
ENST00000551696.1
ENST00000316299.5
 PRKAG1
 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr4_-_54930790 0.23 ENST00000263921.3
 CHIC2
 cysteine-rich hydrophobic domain 2
chr6_+_127588020 0.23 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
 RNF146
 ring finger protein 146
chr15_-_72668185 0.23 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
 HEXA
 hexosaminidase A (alpha polypeptide)
chr1_+_32645645 0.22 ENST00000373609.1
 TXLNA
 taxilin alpha
chr9_+_99212403 0.22 ENST00000375251.3
ENST00000375249.4
 HABP4
 hyaluronan binding protein 4
chr1_+_32645269 0.22 ENST00000373610.3
 TXLNA
 taxilin alpha
chr9_-_123476612 0.22 ENST00000426959.1
 MEGF9
 multiple EGF-like-domains 9
chr17_-_15466742 0.22 ENST00000584811.1
ENST00000419890.2
 TVP23C
 trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr9_-_123476719 0.22 ENST00000373930.3
 MEGF9
 multiple EGF-like-domains 9
chr14_+_77787227 0.22 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
 GSTZ1
 glutathione S-transferase zeta 1
chr17_+_57642886 0.22 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
 DHX40
 DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_-_145016692 0.22 ENST00000357649.2
 PLEC
 plectin
chr19_-_52227221 0.22 ENST00000222115.1
ENST00000540069.2
 HAS1
 hyaluronan synthase 1
chr1_-_85040090 0.22 ENST00000370630.5
 CTBS
 chitobiase, di-N-acetyl-
chr6_-_25042231 0.21 ENST00000510784.2
 FAM65B
 family with sequence similarity 65, member B
chr17_+_7211280 0.21 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
 EIF5A
 eukaryotic translation initiation factor 5A
chr7_-_27169801 0.21 ENST00000511914.1
 HOXA4
 homeobox A4
chr8_+_109455845 0.21 ENST00000220853.3
 EMC2
 ER membrane protein complex subunit 2
chr20_+_34043085 0.21 ENST00000397527.1
ENST00000342580.4
 CEP250
 centrosomal protein 250kDa
chr8_+_61429416 0.21 ENST00000262646.7
ENST00000531289.1
 RAB2A
 RAB2A, member RAS oncogene family
chr11_+_118230287 0.20 ENST00000252108.3
ENST00000431736.2
 UBE4A
 ubiquitination factor E4A
chrX_-_153059811 0.20 ENST00000427365.2
ENST00000444450.1
ENST00000370093.1
 IDH3G
 isocitrate dehydrogenase 3 (NAD+) gamma
chr12_-_125398850 0.20 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
 UBC
 ubiquitin C
chr19_+_2269485 0.20 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
 OAZ1
 ornithine decarboxylase antizyme 1
chr8_+_22422749 0.20 ENST00000523900.1
 SORBS3
 sorbin and SH3 domain containing 3
chr20_+_2821340 0.20 ENST00000380445.3
ENST00000380469.3
 VPS16
 vacuolar protein sorting 16 homolog (S. cerevisiae)
chr3_-_139108475 0.20 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
 COPB2
 coatomer protein complex, subunit beta 2 (beta prime)
chr5_+_151151504 0.19 ENST00000356245.3
ENST00000507878.2
 G3BP1
 GTPase activating protein (SH3 domain) binding protein 1
chr8_+_97657449 0.19 ENST00000220763.5
 CPQ
 carboxypeptidase Q
chr17_-_7197881 0.19 ENST00000007699.5
 YBX2
 Y box binding protein 2
chrX_-_102319092 0.19 ENST00000372728.3
 BEX1
 brain expressed, X-linked 1
chr12_+_54447637 0.19 ENST00000609810.1
ENST00000430889.2
 HOXC4
HOXC4
 homeobox C4
Homeobox protein Hox-C4
chr3_+_51428704 0.18 ENST00000323686.4
 RBM15B
 RNA binding motif protein 15B
chr21_-_38445297 0.18 ENST00000430792.1
ENST00000399103.1
 PIGP
 phosphatidylinositol glycan anchor biosynthesis, class P
chr8_+_133787586 0.18 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
 PHF20L1
 PHD finger protein 20-like 1
chr10_+_103825080 0.18 ENST00000299238.5
 HPS6
 Hermansky-Pudlak syndrome 6
chrX_-_139587225 0.17 ENST00000370536.2
 SOX3
 SRY (sex determining region Y)-box 3
chr16_-_86588627 0.17 ENST00000565482.1
ENST00000564364.1
ENST00000561989.1
ENST00000543303.2
ENST00000381214.5
ENST00000360900.6
ENST00000322911.6
ENST00000546093.1
ENST00000569000.1
ENST00000562994.1
ENST00000561522.1
 MTHFSD
 methenyltetrahydrofolate synthetase domain containing

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.8 4.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 2.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 1.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.6 GO:0016015 morphogen activity(GO:0016015)
0.2 1.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 1.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 1.2 GO:0036122 BMP binding(GO:0036122)
0.1 0.6 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.7 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 1.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.7 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 1.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.2 GO:0008061 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.8 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.0 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.8 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.9 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.5 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 8.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 1.3 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.5 1.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.5 2.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.5 1.4 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.3 1.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 1.0 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3 5.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.3 1.2 GO:0035720 signal transduction downstream of smoothened(GO:0007227) intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.2 1.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.2 0.6 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 2.3 GO:0045176 apical protein localization(GO:0045176)
0.2 0.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.2 1.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.2 0.8 GO:0002572 pro-T cell differentiation(GO:0002572)
0.2 0.9 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 0.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 1.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 2.0 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.8 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 1.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 1.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.6 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.6 GO:0042908 xenobiotic transport(GO:0042908)
0.1 1.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.6 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 3.6 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860) specification of axis polarity(GO:0065001)
0.0 0.8 GO:0034329 cell junction assembly(GO:0034329)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 1.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0045007 DNA dealkylation involved in DNA repair(GO:0006307) depurination(GO:0045007)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0035655 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128) interleukin-18-mediated signaling pathway(GO:0035655)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 1.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 1.6 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0003016 respiratory system process(GO:0003016)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.1 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.4 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.3 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 4.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 3.7 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.1 0.9 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 4.2 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.9 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 2.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.1 GO:0001652 granular component(GO:0001652)
0.2 1.0 GO:0033263 CORVET complex(GO:0033263)
0.2 1.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 3.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 0.8 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.2 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.7 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.6 GO:0097227 sperm annulus(GO:0097227)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 2.3 GO:0042599 lamellar body(GO:0042599)
0.1 1.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.7 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 0.3 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.6 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122) endolysosome membrane(GO:0036020)
0.0 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 4.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events