ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
BACH1 Links Ensembl NCBI GeneCards UniProt	ENSG00000156273.11	BACH1
NFE2 Links Ensembl NCBI GeneCards UniProt	ENSG00000123405.9	NFE2
NFE2L2 Links Ensembl NCBI GeneCards UniProt	ENSG00000116044.11	NFE2L2

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NFE2	hg19_v2_chr12_-_54689532_54689551, hg19_v2_chr12_-_54694807_54694905, hg19_v2_chr12_-_54694758_54694805	0.81	1.6e-04	Click!
NFE2L2	hg19_v2_chr2_-_178128250_178128300, hg19_v2_chr2_-_178257401_178257432, hg19_v2_chr2_-_178128528_178128574, hg19_v2_chr2_-_178129853_178129860	-0.59	1.5e-02	Click!
BACH1	hg19_v2_chr21_+_30671189_30671207, hg19_v2_chr21_+_30671690_30671762	0.39	1.3e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chrX_-_154563889	8.17	ENST00000369449.2 ENST00000321926.4	CLIC2	chloride intracellular channel 2
chr8_-_30585217	5.26	ENST00000520888.1 ENST00000414019.1	GSR	glutathione reductase
chr8_-_30585294	5.13	ENST00000546342.1 ENST00000541648.1 ENST00000537535.1	GSR	glutathione reductase
chr8_-_30585439	5.11	ENST00000221130.5	GSR	glutathione reductase
chr2_-_220083076	4.17	ENST00000295750.4	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_158656488	3.76	ENST00000368147.4	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr22_+_19466980	3.71	ENST00000407835.1 ENST00000438587.1	CDC45	cell division cycle 45
chr7_+_112063192	3.62	ENST00000005558.4	IFRD1	interferon-related developmental regulator 1
chr17_+_30771279	3.44	ENST00000261712.3 ENST00000578213.1 ENST00000457654.2 ENST00000579451.1	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_-_225616515	3.10	ENST00000338179.2 ENST00000425080.1	LBR	lamin B receptor
chr6_-_35888905	2.71	ENST00000510290.1 ENST00000423325.2 ENST00000373822.1	SRPK1	SRSF protein kinase 1
chr6_+_32121218	2.63	ENST00000414204.1 ENST00000361568.2 ENST00000395523.1	PPT2	palmitoyl-protein thioesterase 2
chr6_+_44214824	2.48	ENST00000371646.5 ENST00000353801.3	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr5_-_137911049	2.46	ENST00000297185.3	HSPA9	heat shock 70kDa protein 9 (mortalin)
chr10_-_6019984	2.25	ENST00000525219.2	IL15RA	interleukin 15 receptor, alpha
chr14_+_58711539	2.02	ENST00000216455.4 ENST00000412908.2 ENST00000557508.1	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr16_-_1429627	1.96	ENST00000248104.7	UNKL	unkempt family zinc finger-like
chr10_-_76868931	1.90	ENST00000372700.3 ENST00000473072.2 ENST00000491677.2 ENST00000607131.1 ENST00000372702.3	DUSP13	dual specificity phosphatase 13
chr17_-_79881408	1.84	ENST00000392366.3	MAFG	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr6_+_44215603	1.80	ENST00000371554.1	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr10_-_6019552	1.80	ENST00000379977.3 ENST00000397251.3 ENST00000397248.2	IL15RA	interleukin 15 receptor, alpha
chr17_-_28618948	1.78	ENST00000261714.6	BLMH	bleomycin hydrolase
chr18_-_55253989	1.77	ENST00000262093.5	FECH	ferrochelatase
chr6_-_35888824	1.61	ENST00000361690.3 ENST00000512445.1	SRPK1	SRSF protein kinase 1
chr16_-_28222797	1.60	ENST00000569951.1 ENST00000565698.1	XPO6	exportin 6
chr21_+_33031935	1.55	ENST00000270142.6 ENST00000389995.4	SOD1	superoxide dismutase 1, soluble
chr11_+_46402297	1.53	ENST00000405308.2	MDK	midkine (neurite growth-promoting factor 2)
chr2_-_220173685	1.51	ENST00000423636.2 ENST00000442029.1 ENST00000412847.1	PTPRN	protein tyrosine phosphatase, receptor type, N
chr17_-_28618867	1.51	ENST00000394819.3 ENST00000577623.1	BLMH	bleomycin hydrolase
chr11_+_118958689	1.48	ENST00000535253.1 ENST00000392841.1	HMBS	hydroxymethylbilane synthase
chr19_-_59023348	1.40	ENST00000601355.1 ENST00000263093.2	SLC27A5	solute carrier family 27 (fatty acid transporter), member 5
chr17_-_73150629	1.36	ENST00000356033.4 ENST00000405458.3 ENST00000409753.3	HN1	hematological and neurological expressed 1
chr17_+_76311791	1.33	ENST00000586321.1	AC061992.2	AC061992.2
chr14_+_103801140	1.30	ENST00000561325.1 ENST00000392715.2 ENST00000559130.1 ENST00000559532.1 ENST00000558506.1	EIF5	eukaryotic translation initiation factor 5
chrX_+_153770421	1.29	ENST00000369609.5 ENST00000369607.1	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr1_-_200992827	1.28	ENST00000332129.2 ENST00000422435.2	KIF21B	kinesin family member 21B
chr12_-_71182695	1.26	ENST00000342084.4	PTPRR	protein tyrosine phosphatase, receptor type, R
chr16_-_1429674	1.22	ENST00000403703.1 ENST00000397464.1 ENST00000402641.2	UNKL	unkempt family zinc finger-like
chr16_+_30077055	1.22	ENST00000564595.2 ENST00000569798.1	ALDOA	aldolase A, fructose-bisphosphate
chr3_-_48057890	1.13	ENST00000434267.1	MAP4	microtubule-associated protein 4
chr2_-_11606275	1.12	ENST00000381525.3 ENST00000362009.4	E2F6	E2F transcription factor 6
chr1_-_150208291	1.11	ENST00000533654.1	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_25756638	1.09	ENST00000349320.3	RHCE	Rh blood group, CcEe antigens
chr10_+_45495898	1.05	ENST00000298299.3	ZNF22	zinc finger protein 22
chr8_-_38386175	1.02	ENST00000437935.2 ENST00000358138.1	C8orf86	chromosome 8 open reading frame 86
chr7_+_22766766	1.01	ENST00000426291.1 ENST00000401651.1 ENST00000258743.5 ENST00000420258.2 ENST00000407492.1 ENST00000401630.3 ENST00000406575.1	IL6	interleukin 6 (interferon, beta 2)
chr15_-_83240507	1.00	ENST00000564522.1 ENST00000398592.2	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr3_-_98241358	1.00	ENST00000503004.1 ENST00000506575.1 ENST00000513452.1 ENST00000515620.1	CLDND1	claudin domain containing 1
chr15_-_83240553	0.98	ENST00000423133.2 ENST00000398591.2	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr1_-_150208320	0.97	ENST00000534220.1	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_62474803	0.96	ENST00000533982.1 ENST00000360796.5	BSCL2	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr3_+_184037466	0.96	ENST00000441154.1	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr1_-_150208363	0.94	ENST00000436748.2	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_+_184038073	0.93	ENST00000428387.1 ENST00000434061.2	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr6_+_36410762	0.93	ENST00000483557.1 ENST00000498267.1 ENST00000544295.1 ENST00000449081.2 ENST00000536244.1 ENST00000460983.1	KCTD20	potassium channel tetramerization domain containing 20
chrX_-_15511438	0.92	ENST00000380420.5	PIR	pirin (iron-binding nuclear protein)
chr7_+_130794846	0.92	ENST00000421797.2	MKLN1	muskelin 1, intracellular mediator containing kelch motifs
chr19_-_10613421	0.91	ENST00000393623.2	KEAP1	kelch-like ECH-associated protein 1
chr3_+_183903811	0.91	ENST00000429586.2 ENST00000292808.5	ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3
chr19_-_46285646	0.88	ENST00000458663.2	DMPK	dystrophia myotonica-protein kinase
chr12_+_64845660	0.88	ENST00000331710.5	TBK1	TANK-binding kinase 1
chr18_-_55253871	0.87	ENST00000382873.3	FECH	ferrochelatase
chr22_-_19466683	0.87	ENST00000399523.1 ENST00000421968.2 ENST00000447868.1	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr1_-_109968973	0.84	ENST00000271308.4 ENST00000538610.1	PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr11_-_9025541	0.83	ENST00000525100.1 ENST00000309166.3 ENST00000531090.1	NRIP3	nuclear receptor interacting protein 3
chr17_-_42276574	0.83	ENST00000589805.1	ATXN7L3	ataxin 7-like 3
chr1_-_150208412	0.78	ENST00000532744.1 ENST00000369114.5 ENST00000369115.2 ENST00000369116.4	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_14541872	0.77	ENST00000419365.2 ENST00000530457.1 ENST00000532256.1 ENST00000533068.1	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1
chr1_-_150208498	0.73	ENST00000314136.8	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_+_35484793	0.73	ENST00000488741.1 ENST00000474931.1 ENST00000468236.1 ENST00000344351.5 ENST00000490511.1	CREM	cAMP responsive element modulator
chr22_-_19466732	0.73	ENST00000263202.10 ENST00000360834.4	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr16_-_23521710	0.72	ENST00000562117.1 ENST00000567468.1 ENST00000562944.1 ENST00000309859.4	GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr4_+_170581213	0.72	ENST00000507875.1	CLCN3	chloride channel, voltage-sensitive 3
chr1_+_165796753	0.71	ENST00000367879.4	UCK2	uridine-cytidine kinase 2
chr16_+_12059091	0.71	ENST00000562385.1	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr8_-_59572093	0.71	ENST00000427130.2	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr22_+_18893736	0.71	ENST00000331444.6	DGCR6	DiGeorge syndrome critical region gene 6
chr13_-_67802549	0.71	ENST00000328454.5 ENST00000377865.2	PCDH9	protocadherin 9
chr17_+_55162453	0.70	ENST00000575322.1 ENST00000337714.3 ENST00000314126.3	AKAP1	A kinase (PRKA) anchor protein 1
chr17_-_61905005	0.70	ENST00000584574.1 ENST00000585145.1 ENST00000427159.2	FTSJ3	FtsJ homolog 3 (E. coli)
chr10_+_35484053	0.70	ENST00000487763.1 ENST00000473940.1 ENST00000488328.1 ENST00000356917.5	CREM	cAMP responsive element modulator
chr10_+_85899196	0.69	ENST00000372134.3	GHITM	growth hormone inducible transmembrane protein
chr7_+_100026406	0.68	ENST00000414441.1	MEPCE	methylphosphate capping enzyme
chrX_-_16730688	0.68	ENST00000359276.4	CTPS2	CTP synthase 2
chr7_+_101460882	0.68	ENST00000292535.7 ENST00000549414.2 ENST00000550008.2 ENST00000546411.2 ENST00000556210.1	CUX1	cut-like homeobox 1
chr14_+_103589789	0.68	ENST00000558056.1 ENST00000560869.1	TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr16_+_30211181	0.67	ENST00000395138.2	SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr3_+_69915385	0.67	ENST00000314589.5	MITF	microphthalmia-associated transcription factor
chr16_+_22308717	0.66	ENST00000299853.5 ENST00000564209.1 ENST00000565358.1 ENST00000418581.2 ENST00000564883.1 ENST00000359210.4 ENST00000563024.1	POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr22_-_32058166	0.65	ENST00000435900.1 ENST00000336566.4	PISD	phosphatidylserine decarboxylase
chr6_-_31704282	0.64	ENST00000375784.3 ENST00000375779.2	CLIC1	chloride intracellular channel 1
chr1_+_76251879	0.64	ENST00000535300.1 ENST00000319942.3	RABGGTB	Rab geranylgeranyltransferase, beta subunit
chr12_-_15114492	0.63	ENST00000541546.1	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr1_-_12677714	0.63	ENST00000376223.2	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr6_-_3157760	0.63	ENST00000333628.3	TUBB2A	tubulin, beta 2A class IIa
chrX_-_16730984	0.63	ENST00000380241.3	CTPS2	CTP synthase 2
chr17_+_61905058	0.62	ENST00000375812.4 ENST00000581882.1	PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5
chr16_+_12059050	0.62	ENST00000396495.3	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr19_+_926000	0.61	ENST00000263620.3	ARID3A	AT rich interactive domain 3A (BRIGHT-like)
chr9_+_139921916	0.61	ENST00000314330.2	C9orf139	chromosome 9 open reading frame 139
chr5_+_118690466	0.60	ENST00000503646.1	TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr2_+_122513109	0.58	ENST00000389682.3 ENST00000536142.1	TSN	translin
chr1_-_39339777	0.58	ENST00000397572.2	MYCBP	MYC binding protein
chrX_-_109683446	0.56	ENST00000372057.1	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_+_84569359	0.56	ENST00000369681.5 ENST00000369679.4	CYB5R4	cytochrome b5 reductase 4
chr20_+_60878005	0.55	ENST00000253003.2	ADRM1	adhesion regulating molecule 1
chr14_-_95942173	0.55	ENST00000334258.5 ENST00000557275.1 ENST00000553340.1	SYNE3	spectrin repeat containing, nuclear envelope family member 3
chr8_-_59572301	0.54	ENST00000038176.3	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr4_-_987217	0.54	ENST00000361661.2 ENST00000398516.2	SLC26A1	solute carrier family 26 (anion exchanger), member 1
chr11_-_9781068	0.53	ENST00000500698.1	RP11-540A21.2	RP11-540A21.2
chr10_-_94333784	0.53	ENST00000265986.6	IDE	insulin-degrading enzyme
chr11_-_2924970	0.53	ENST00000533594.1	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense
chr8_-_82395461	0.53	ENST00000256104.4	FABP4	fatty acid binding protein 4, adipocyte
chr16_+_29819446	0.52	ENST00000568282.1	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr16_-_15180257	0.50	ENST00000540462.1	RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr20_+_34742650	0.50	ENST00000373945.1 ENST00000338074.2	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr22_+_23165153	0.50	ENST00000390317.2	IGLV2-8	immunoglobulin lambda variable 2-8
chr18_+_21693306	0.49	ENST00000540918.2	TTC39C	tetratricopeptide repeat domain 39C
chr6_+_33378738	0.49	ENST00000374512.3 ENST00000374516.3	PHF1	PHD finger protein 1
chrX_+_99899180	0.48	ENST00000373004.3	SRPX2	sushi-repeat containing protein, X-linked 2
chr15_+_78833071	0.48	ENST00000559365.1	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4
chr17_+_79935464	0.48	ENST00000581647.1 ENST00000580534.1 ENST00000579684.1	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr11_+_63448918	0.47	ENST00000341307.2 ENST00000356000.3 ENST00000542238.1	RTN3	reticulon 3
chr1_+_17634689	0.47	ENST00000375453.1 ENST00000375448.4	PADI4	peptidyl arginine deiminase, type IV
chr6_-_39902160	0.45	ENST00000340692.5	MOCS1	molybdenum cofactor synthesis 1
chr16_+_30077098	0.45	ENST00000395240.3 ENST00000566846.1	ALDOA	aldolase A, fructose-bisphosphate
chr7_-_129845188	0.45	ENST00000462753.1 ENST00000471077.1 ENST00000473456.1 ENST00000336804.8	TMEM209	transmembrane protein 209
chr11_-_47447767	0.45	ENST00000530651.1 ENST00000524447.2 ENST00000531051.2 ENST00000526993.1 ENST00000602866.1	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chrX_+_22056165	0.44	ENST00000535894.1	PHEX	phosphate regulating endopeptidase homolog, X-linked
chr9_+_116267536	0.44	ENST00000374136.1	RGS3	regulator of G-protein signaling 3
chr15_+_78832747	0.44	ENST00000560217.1 ENST00000044462.7 ENST00000559082.1 ENST00000559948.1 ENST00000413382.2 ENST00000559146.1 ENST00000558281.1	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4
chr11_+_10477733	0.44	ENST00000528723.1	AMPD3	adenosine monophosphate deaminase 3
chr19_+_18496957	0.44	ENST00000252809.3	GDF15	growth differentiation factor 15
chr12_-_26986076	0.44	ENST00000381340.3	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2
chr4_-_146019693	0.43	ENST00000514390.1	ANAPC10	anaphase promoting complex subunit 10
chr5_+_179247759	0.43	ENST00000389805.4 ENST00000504627.1 ENST00000402874.3 ENST00000510187.1	SQSTM1	sequestosome 1
chr7_+_102988082	0.43	ENST00000292644.3 ENST00000544811.1	PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr5_+_179125368	0.42	ENST00000502296.1 ENST00000504734.1 ENST00000415618.2	CANX	calnexin
chr13_-_41593425	0.42	ENST00000239882.3	ELF1	E74-like factor 1 (ets domain transcription factor)
chr17_+_18759612	0.42	ENST00000432893.2 ENST00000414602.1 ENST00000574522.1 ENST00000570450.1 ENST00000419071.2	PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2
chr6_-_28321971	0.42	ENST00000396838.2 ENST00000426434.1 ENST00000434036.1 ENST00000439628.1	ZSCAN31	zinc finger and SCAN domain containing 31
chr19_-_6670128	0.41	ENST00000245912.3	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14
chr2_+_231921574	0.41	ENST00000308696.6 ENST00000373635.4 ENST00000440838.1 ENST00000409643.1	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr1_+_14075865	0.41	ENST00000413440.1	PRDM2	PR domain containing 2, with ZNF domain
chr7_-_115670804	0.40	ENST00000320239.7	TFEC	transcription factor EC
chr2_+_74781828	0.40	ENST00000340004.6	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr5_-_175964366	0.40	ENST00000274811.4	RNF44	ring finger protein 44
chr4_+_17616253	0.39	ENST00000237380.7	MED28	mediator complex subunit 28
chr22_-_31063782	0.39	ENST00000404885.1 ENST00000403268.1 ENST00000407308.1 ENST00000342474.4 ENST00000334679.3	DUSP18	dual specificity phosphatase 18
chr1_+_14075903	0.39	ENST00000343137.4 ENST00000503842.1 ENST00000407521.3 ENST00000505823.1	PRDM2	PR domain containing 2, with ZNF domain
chr11_-_65430251	0.39	ENST00000534283.1 ENST00000527749.1 ENST00000533187.1 ENST00000525693.1 ENST00000534558.1 ENST00000532879.1 ENST00000532999.1	RELA	v-rel avian reticuloendotheliosis viral oncogene homolog A
chr1_+_100111580	0.39	ENST00000605497.1	PALMD	palmdelphin
chr22_+_22681656	0.38	ENST00000390291.2	IGLV1-50	immunoglobulin lambda variable 1-50 (non-functional)
chr20_-_48782639	0.38	ENST00000435301.2	RP11-112L6.3	RP11-112L6.3
chr15_+_41851211	0.38	ENST00000263798.3	TYRO3	TYRO3 protein tyrosine kinase
chr22_+_22730353	0.38	ENST00000390296.2	IGLV5-45	immunoglobulin lambda variable 5-45
chr8_-_95220775	0.37	ENST00000441892.2 ENST00000521491.1 ENST00000027335.3	CDH17	cadherin 17, LI cadherin (liver-intestine)
chr6_-_31745085	0.37	ENST00000375686.3 ENST00000447450.1	VWA7	von Willebrand factor A domain containing 7
chr8_-_94753229	0.36	ENST00000518597.1 ENST00000399300.2 ENST00000517700.1	RBM12B	RNA binding motif protein 12B
chr4_-_26492076	0.36	ENST00000295589.3	CCKAR	cholecystokinin A receptor
chr7_+_150434430	0.36	ENST00000358647.3	GIMAP5	GTPase, IMAP family member 5
chr7_-_115670792	0.36	ENST00000265440.7 ENST00000393485.1	TFEC	transcription factor EC
chr19_-_49658387	0.36	ENST00000595625.1	HRC	histidine rich calcium binding protein
chr6_-_31745037	0.36	ENST00000375688.4	VWA7	von Willebrand factor A domain containing 7
chr9_-_116840728	0.36	ENST00000265132.3	AMBP	alpha-1-microglobulin/bikunin precursor
chr17_+_61904766	0.35	ENST00000581842.1 ENST00000582130.1 ENST00000584320.1 ENST00000585123.1 ENST00000580864.1	PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5
chr11_-_47447970	0.35	ENST00000298852.3 ENST00000530912.1	PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr2_-_89417335	0.35	ENST00000490686.1	IGKV1-17	immunoglobulin kappa variable 1-17
chr3_-_119276575	0.35	ENST00000383669.3 ENST00000383668.3	CD80	CD80 molecule
chr11_+_125365110	0.35	ENST00000527818.1	AP000708.1	AP000708.1
chr12_-_15114603	0.35	ENST00000228945.4	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta
chr1_+_156756667	0.35	ENST00000526188.1 ENST00000454659.1	PRCC	papillary renal cell carcinoma (translocation-associated)
chr4_+_123747834	0.34	ENST00000264498.3	FGF2	fibroblast growth factor 2 (basic)
chr6_-_39902185	0.34	ENST00000373195.3 ENST00000308559.7 ENST00000373188.2	MOCS1	molybdenum cofactor synthesis 1
chr18_-_52989217	0.34	ENST00000570287.2	TCF4	transcription factor 4
chr17_-_74733404	0.34	ENST00000508921.3 ENST00000583836.1 ENST00000358156.6 ENST00000392485.2 ENST00000359995.5	SRSF2	serine/arginine-rich splicing factor 2
chr22_+_39353527	0.33	ENST00000249116.2	APOBEC3A	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr6_-_166582107	0.33	ENST00000296946.2 ENST00000461348.2 ENST00000366871.3	T	T, brachyury homolog (mouse)
chr2_-_89385283	0.33	ENST00000390252.2	IGKV3-15	immunoglobulin kappa variable 3-15
chr3_-_98241760	0.33	ENST00000507874.1 ENST00000502299.1 ENST00000508659.1 ENST00000510545.1 ENST00000511667.1 ENST00000394185.2 ENST00000394181.2 ENST00000508902.1 ENST00000341181.6 ENST00000437922.1 ENST00000394180.2	CLDND1	claudin domain containing 1
chr10_-_21786179	0.32	ENST00000377113.5	CASC10	cancer susceptibility candidate 10
chr12_-_113909877	0.32	ENST00000261731.3	LHX5	LIM homeobox 5
chrX_-_119445306	0.31	ENST00000371369.4 ENST00000440464.1 ENST00000519908.1	TMEM255A	transmembrane protein 255A
chr4_+_120056939	0.31	ENST00000307128.5	MYOZ2	myozenin 2
chr11_-_2906979	0.30	ENST00000380725.1 ENST00000313407.6 ENST00000430149.2 ENST00000440480.2 ENST00000414822.3	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr14_+_103800513	0.30	ENST00000560338.1 ENST00000560763.1 ENST00000558316.1 ENST00000558265.1	EIF5	eukaryotic translation initiation factor 5
chr9_+_141107506	0.30	ENST00000446912.2	FAM157B	family with sequence similarity 157, member B
chr7_-_102985035	0.30	ENST00000426036.2 ENST00000249270.7 ENST00000454277.1 ENST00000412522.1	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2
chr2_-_169887827	0.30	ENST00000263817.6	ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr12_-_53343602	0.30	ENST00000546897.1 ENST00000552551.1	KRT8	keratin 8
chr11_+_67007518	0.30	ENST00000530342.1 ENST00000308783.5	KDM2A	lysine (K)-specific demethylase 2A
chr6_+_87646995	0.30	ENST00000305344.5	HTR1E	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
chr11_-_64511789	0.29	ENST00000419843.1 ENST00000394430.1	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr12_-_51611477	0.29	ENST00000389243.4	POU6F1	POU class 6 homeobox 1
chr1_-_156399184	0.29	ENST00000368243.1 ENST00000357975.4 ENST00000310027.5 ENST00000400991.2	C1orf61	chromosome 1 open reading frame 61
chr2_+_45878790	0.29	ENST00000306156.3	PRKCE	protein kinase C, epsilon
chr3_+_140660634	0.29	ENST00000446041.2 ENST00000507429.1 ENST00000324194.6	SLC25A36	solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr2_-_10588630	0.29	ENST00000234111.4	ODC1	ornithine decarboxylase 1
chr17_-_45266542	0.29	ENST00000531206.1 ENST00000527547.1 ENST00000446365.2 ENST00000575483.1 ENST00000066544.3	CDC27	cell division cycle 27
chrX_-_119445263	0.29	ENST00000309720.5	TMEM255A	transmembrane protein 255A

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	15.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3	4.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	3.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	1.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	9.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1	0.9	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.1	4.3	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	3.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	1.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	3.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.9	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	1.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	2.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.5	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.9	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.7	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.6	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	3.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	4.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.5	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	2.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.5	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	1.7	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	2.0	PID AURORA B PATHWAY	Aurora B signaling
0.0	4.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	2.0	PID AURORA A PATHWAY	Aurora A signaling
0.0	4.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	1.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.9	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.6	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.9	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.9	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	1.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0031938	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.2	3.6	GO:0007518	myoblast fate determination(GO:0007518)
1.1	4.3	GO:1903660	negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.9	2.6	GO:0070541	response to platinum ion(GO:0070541)
0.6	7.8	GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.5	3.3	GO:0043418	homocysteine catabolic process(GO:0043418)
0.5	1.5	GO:1990502	dense core granule maturation(GO:1990502)
0.4	1.3	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.4	4.3	GO:0035092	sperm chromatin condensation(GO:0035092)
0.4	4.2	GO:0015886	heme transport(GO:0015886)
0.3	1.0	GO:0002384	hepatic immune response(GO:0002384) response to prolactin(GO:1990637) regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.3	2.6	GO:0098734	macromolecule depalmitoylation(GO:0098734)
0.3	1.5	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.3	2.5	GO:1902037	negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.3	14.1	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.3	0.5	GO:1901143	insulin catabolic process(GO:1901143)
0.3	1.5	GO:0030421	defecation(GO:0030421)
0.2	2.0	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.2	1.0	GO:0071461	cellular response to redox state(GO:0071461)
0.2	3.9	GO:0043248	proteasome assembly(GO:0043248)
0.2	0.9	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.2	1.9	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.2	1.3	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.2	1.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.2	1.1	GO:0051012	microtubule sliding(GO:0051012)
0.2	0.7	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2	0.5	GO:1901899	positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1	0.4	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1	1.6	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.7	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.6	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.4	GO:0038188	cholecystokinin signaling pathway(GO:0038188)
0.1	0.7	GO:0040031	snRNA modification(GO:0040031)
0.1	1.2	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.3	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.1	0.9	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.5	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1	0.4	GO:0014040	positive regulation of Schwann cell differentiation(GO:0014040)
0.1	4.5	GO:0043486	histone exchange(GO:0043486)
0.1	0.3	GO:0051083	'de novo' cotranslational protein folding(GO:0051083)
0.1	0.8	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1	0.7	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1	1.5	GO:0018065	protein-cofactor linkage(GO:0018065)
0.1	1.7	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1	0.9	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1	0.4	GO:1904383	response to sodium phosphate(GO:1904383)
0.1	2.2	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1	0.3	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.1	0.4	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.5	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.4	GO:0006196	AMP catabolic process(GO:0006196)
0.1	0.3	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.5	GO:0001180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1	0.5	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1	0.6	GO:0018344	protein geranylgeranylation(GO:0018344)
0.1	3.8	GO:0051693	actin filament capping(GO:0051693)
0.1	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	5.6	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.1	0.7	GO:0051601	exocyst localization(GO:0051601)
0.1	0.2	GO:0072183	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.3	GO:0015722	canalicular bile acid transport(GO:0015722)
0.1	0.7	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1	0.5	GO:0045006	DNA deamination(GO:0045006)
0.1	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.6	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.6	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.3	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1	0.5	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.1	0.4	GO:0045425	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.5	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.5	GO:0038203	TORC2 signaling(GO:0038203)
0.0	0.3	GO:1902746	regulation of lens fiber cell differentiation(GO:1902746)
0.0	0.4	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.8	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.5	GO:0071285	cellular response to lithium ion(GO:0071285)
0.0	1.0	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.3	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.4	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	1.2	GO:0015695	organic cation transport(GO:0015695)
0.0	0.3	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.7	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.4	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.2	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.4	GO:0060068	vagina development(GO:0060068)
0.0	0.4	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.3	GO:2000576	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.8	GO:0016578	histone deubiquitination(GO:0016578)
0.0	2.8	GO:0006695	cholesterol biosynthetic process(GO:0006695)
0.0	0.1	GO:0035063	nuclear speck organization(GO:0035063)
0.0	0.1	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.0	1.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.6	GO:1901657	glycosyl compound metabolic process(GO:1901657)
0.0	0.1	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	1.8	GO:0045604	regulation of epidermal cell differentiation(GO:0045604)
0.0	1.4	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.3	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.4	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.3	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.7	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0009181	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.9	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.4	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:0006050	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0	0.3	GO:0030239	myofibril assembly(GO:0030239)
0.0	0.1	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.4	GO:0050855	regulation of B cell receptor signaling pathway(GO:0050855)
0.0	0.7	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	1.3	GO:0002260	lymphocyte homeostasis(GO:0002260)
0.0	0.7	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:1901569	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0	0.1	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0	0.1	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	2.2	GO:0030449	regulation of complement activation(GO:0030449)
0.0	1.1	GO:0045669	positive regulation of osteoblast differentiation(GO:0045669)
0.0	0.2	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.1	GO:0051414	response to cortisol(GO:0051414)
0.0	0.1	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.2	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.8	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.2	GO:0007320	insemination(GO:0007320)
0.0	0.3	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0	0.4	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.6	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.6	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.7	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.1	4.3	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.5	3.8	GO:0032437	cuticular plate(GO:0032437)
0.4	4.0	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.4	4.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3	4.0	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.3	0.8	GO:0019008	molybdopterin synthase complex(GO:0019008)
0.3	1.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	4.5	GO:0000812	Swr1 complex(GO:0000812)
0.2	2.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.2	0.6	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2	3.3	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1	0.4	GO:0071159	NF-kappaB complex(GO:0071159)
0.1	0.9	GO:0031597	cytosolic proteasome complex(GO:0031597)
0.1	8.9	GO:0034707	chloride channel complex(GO:0034707)
0.1	0.4	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	2.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	1.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	1.5	GO:0031045	dense core granule(GO:0031045)
0.1	1.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0035061	interchromatin granule(GO:0035061)
0.1	0.8	GO:0000124	SAGA complex(GO:0000124)
0.1	0.3	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0	0.3	GO:1990635	proximal dendrite(GO:1990635)
0.0	16.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.4	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	2.4	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	1.3	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.4	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	1.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.4	GO:0044754	autolysosome(GO:0044754)
0.0	0.7	GO:0000145	exocyst(GO:0000145)
0.0	4.6	GO:0016363	nuclear matrix(GO:0016363)
0.0	0.5	GO:0031932	TORC2 complex(GO:0031932)
0.0	1.0	GO:0016020	membrane(GO:0016020)
0.0	0.7	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.4	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.7	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	1.3	GO:0005871	kinesin complex(GO:0005871)
0.0	0.2	GO:0042584	chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	0.5	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0	2.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.8	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.4	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.1	GO:0019867	outer membrane(GO:0019867)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.5	GO:0043679	axon terminus(GO:0043679)
0.0	1.4	GO:0072562	blood microparticle(GO:0072562)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.2	15.5	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
1.4	4.3	GO:0001884	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
1.4	4.2	GO:0015439	heme-transporting ATPase activity(GO:0015439)
1.0	3.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.4	1.3	GO:0003883	CTP synthase activity(GO:0003883)
0.3	2.6	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3	1.6	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3	1.2	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	0.7	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.2	3.7	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.2	0.6	GO:0004609	phosphatidylserine decarboxylase activity(GO:0004609)
0.2	2.2	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.2	0.5	GO:0001181	transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.2	4.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.2	1.9	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	1.7	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.4	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1	3.9	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	0.6	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.1	2.6	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.1	1.9	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.1	2.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.4	GO:0004951	cholecystokinin receptor activity(GO:0004951)
0.1	0.7	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.1	1.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	0.7	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.7	GO:0004849	uridine kinase activity(GO:0004849)
0.1	1.4	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	1.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	1.4	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	1.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.4	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.6	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.4	GO:0019862	IgA binding(GO:0019862)
0.1	0.5	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	3.9	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	0.3	GO:0035276	ethanol binding(GO:0035276)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.4	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	0.2	GO:0098626	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1	0.3	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
0.1	0.5	GO:0043559	insulin binding(GO:0043559)
0.1	0.4	GO:0071532	ankyrin repeat binding(GO:0071532)
0.1	3.3	GO:0004180	carboxypeptidase activity(GO:0004180)
0.1	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.2	GO:0004796	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.1	0.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.0	0.2	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	1.3	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.7	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.4	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	1.0	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	1.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.8	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.6	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	1.8	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0022865	transmembrane electron transfer carrier(GO:0022865)
0.0	1.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	1.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0052870	tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0	0.7	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.7	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.3	GO:0001087	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.3	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	1.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.1	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.4	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	1.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.4	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.2	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.8	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.3	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	3.7	GO:0051015	actin filament binding(GO:0051015)
0.0	0.8	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.7	GO:0008173	RNA methyltransferase activity(GO:0008173)
0.0	0.1	GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	3.2	GO:0000287	magnesium ion binding(GO:0000287)
0.0	1.1	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0032396	inhibitory MHC class I receptor activity(GO:0032396)
0.0	1.8	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	2.5	GO:0003823	antigen binding(GO:0003823)
0.0	0.9	GO:0051219	phosphoprotein binding(GO:0051219)