ENCODE cell lines, expression (Ernst 2011)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
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Gene Symbol	Gene ID	Gene Info
BARX1 Links Ensembl NCBI GeneCards UniProt	ENSG00000131668.9	BARX1

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BARX1	hg19_v2_chr9_-_96717654_96717666	0.16	5.5e-01	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr12_-_52911718	3.77	ENST00000548409.1	KRT5	keratin 5
chr10_-_95242044	2.80	ENST00000371501.4 ENST00000371502.4 ENST00000371489.1	MYOF	myoferlin
chr10_-_95241951	2.77	ENST00000358334.5 ENST00000359263.4 ENST00000371488.3	MYOF	myoferlin
chr13_-_38172863	2.45	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN	periostin, osteoblast specific factor
chr4_+_169418195	2.41	ENST00000261509.6 ENST00000335742.7	PALLD	palladin, cytoskeletal associated protein
chr18_+_61442629	2.39	ENST00000398019.2 ENST00000540675.1	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_+_12766583	2.35	ENST00000361985.2	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr8_+_30244580	2.21	ENST00000523115.1 ENST00000519647.1	RBPMS	RNA binding protein with multiple splicing
chr7_+_134430212	2.18	ENST00000436461.2	CALD1	caldesmon 1
chr1_-_95391315	2.03	ENST00000545882.1 ENST00000415017.1	CNN3	calponin 3, acidic
chr3_-_149093499	1.98	ENST00000472441.1	TM4SF1	transmembrane 4 L six family member 1
chr5_+_150404904	1.78	ENST00000521632.1	GPX3	glutathione peroxidase 3 (plasma)
chr4_+_169418255	1.74	ENST00000505667.1 ENST00000511948.1	PALLD	palladin, cytoskeletal associated protein
chr2_-_106054952	1.73	ENST00000336660.5 ENST00000393352.3 ENST00000607522.1	FHL2	four and a half LIM domains 2
chr12_-_8803128	1.64	ENST00000543467.1	MFAP5	microfibrillar associated protein 5
chr13_+_73629107	1.56	ENST00000539231.1	KLF5	Kruppel-like factor 5 (intestinal)
chr9_-_113761720	1.53	ENST00000541779.1 ENST00000374430.2	LPAR1	lysophosphatidic acid receptor 1
chr2_-_175711133	1.53	ENST00000409597.1 ENST00000413882.1	CHN1	chimerin 1
chr3_-_185538849	1.53	ENST00000421047.2	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr11_+_114168085	1.51	ENST00000541754.1	NNMT	nicotinamide N-methyltransferase
chr12_+_26348246	1.48	ENST00000422622.2	SSPN	sarcospan
chr12_-_91572278	1.46	ENST00000425043.1 ENST00000420120.2 ENST00000441303.2 ENST00000456569.2	DCN	decorin
chr11_+_35201826	1.43	ENST00000531873.1	CD44	CD44 molecule (Indian blood group)
chrX_-_13835147	1.42	ENST00000493677.1 ENST00000355135.2	GPM6B	glycoprotein M6B
chr5_+_140762268	1.41	ENST00000518325.1	PCDHGA7	protocadherin gamma subfamily A, 7
chr7_+_32996997	1.41	ENST00000242209.4 ENST00000538336.1 ENST00000538443.1	FKBP9	FK506 binding protein 9, 63 kDa
chr14_+_55595762	1.40	ENST00000254301.9	LGALS3	lectin, galactoside-binding, soluble, 3
chr22_-_36220420	1.37	ENST00000473487.2	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr3_-_123512688	1.35	ENST00000475616.1	MYLK	myosin light chain kinase
chr18_+_21529811	1.26	ENST00000588004.1	LAMA3	laminin, alpha 3
chr5_-_16742330	1.22	ENST00000505695.1 ENST00000427430.2	MYO10	myosin X
chr4_-_7873981	1.20	ENST00000360265.4	AFAP1	actin filament associated protein 1
chr12_-_91574142	1.20	ENST00000547937.1	DCN	decorin
chr6_-_52859046	1.19	ENST00000457564.1 ENST00000541324.1 ENST00000370960.1	GSTA4	glutathione S-transferase alpha 4
chr10_-_91011548	1.14	ENST00000456827.1	LIPA	lipase A, lysosomal acid, cholesterol esterase
chr16_-_10652993	1.13	ENST00000536829.1	EMP2	epithelial membrane protein 2
chr7_+_134576317	1.12	ENST00000424922.1 ENST00000495522.1	CALD1	caldesmon 1
chr12_-_91546926	1.11	ENST00000550758.1	DCN	decorin
chr1_+_73771844	1.07	ENST00000440762.1 ENST00000444827.1 ENST00000415686.1 ENST00000411903.1	RP4-598G3.1	RP4-598G3.1
chr10_-_79398250	1.07	ENST00000286627.5	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr11_+_44117260	1.07	ENST00000358681.4	EXT2	exostosin glycosyltransferase 2
chrX_-_114252193	1.05	ENST00000243213.1	IL13RA2	interleukin 13 receptor, alpha 2
chrX_-_114253536	1.03	ENST00000371936.1	IL13RA2	interleukin 13 receptor, alpha 2
chr15_-_56757329	0.99	ENST00000260453.3	MNS1	meiosis-specific nuclear structural 1
chr7_+_134576151	0.99	ENST00000393118.2	CALD1	caldesmon 1
chr11_+_44117099	0.95	ENST00000533608.1	EXT2	exostosin glycosyltransferase 2
chr12_+_26274917	0.94	ENST00000538142.1	SSPN	sarcospan
chr9_+_139874683	0.94	ENST00000444903.1	PTGDS	prostaglandin D2 synthase 21kDa (brain)
chr1_+_196788887	0.94	ENST00000320493.5 ENST00000367424.4 ENST00000367421.3	CFHR1 CFHR2	complement factor H-related 1 complement factor H-related 2
chr4_+_26585538	0.93	ENST00000264866.4	TBC1D19	TBC1 domain family, member 19
chr21_+_39644305	0.89	ENST00000398930.1	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_31361543	0.89	ENST00000349752.5	GALNT14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr4_+_26585686	0.88	ENST00000505206.1 ENST00000511789.1	TBC1D19	TBC1 domain family, member 19
chr1_-_227505289	0.86	ENST00000366765.3	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr14_+_55595960	0.85	ENST00000554715.1	LGALS3	lectin, galactoside-binding, soluble, 3
chr12_+_19282643	0.85	ENST00000317589.4 ENST00000355397.3 ENST00000359180.3 ENST00000309364.4 ENST00000540972.1 ENST00000429027.2	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr17_+_18601299	0.85	ENST00000572555.1 ENST00000395902.3 ENST00000449552.2	TRIM16L	tripartite motif containing 16-like
chr6_-_2971429	0.84	ENST00000380529.1	SERPINB6	serpin peptidase inhibitor, clade B (ovalbumin), member 6
chrX_-_41449204	0.84	ENST00000378179.3	CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_+_61086917	0.83	ENST00000424789.2 ENST00000389520.4	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr1_+_78470530	0.82	ENST00000370763.5	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr19_-_55660561	0.82	ENST00000587758.1 ENST00000356783.5 ENST00000291901.8 ENST00000588426.1 ENST00000588147.1 ENST00000536926.1 ENST00000588981.1	TNNT1	troponin T type 1 (skeletal, slow)
chr3_-_151034734	0.82	ENST00000260843.4	GPR87	G protein-coupled receptor 87
chr8_+_9046503	0.82	ENST00000512942.2	RP11-10A14.5	RP11-10A14.5
chr5_-_125930929	0.80	ENST00000553117.1 ENST00000447989.2 ENST00000409134.3	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr19_+_41281416	0.78	ENST00000597140.1	MIA	melanoma inhibitory activity
chr9_-_21974820	0.76	ENST00000579122.1 ENST00000498124.1	CDKN2A	cyclin-dependent kinase inhibitor 2A
chr5_+_140743859	0.76	ENST00000518069.1	PCDHGA5	protocadherin gamma subfamily A, 5
chr2_+_234621551	0.75	ENST00000608381.1 ENST00000373414.3	UGT1A1 UGT1A5	UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5
chr2_-_190927447	0.75	ENST00000260950.4	MSTN	myostatin
chr19_-_36643329	0.75	ENST00000589154.1	COX7A1	cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr13_+_102142296	0.73	ENST00000376162.3	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_10978957	0.71	ENST00000240619.2	TAS2R10	taste receptor, type 2, member 10
chr7_+_16793160	0.71	ENST00000262067.4	TSPAN13	tetraspanin 13
chr1_+_156030937	0.66	ENST00000361084.5	RAB25	RAB25, member RAS oncogene family
chrX_-_134156502	0.66	ENST00000391440.1	FAM127C	family with sequence similarity 127, member C
chr1_+_172389821	0.64	ENST00000367727.4	C1orf105	chromosome 1 open reading frame 105
chr1_-_109584768	0.64	ENST00000357672.3	WDR47	WD repeat domain 47
chr16_-_66584059	0.64	ENST00000417693.3 ENST00000544898.1 ENST00000569718.1 ENST00000527284.1 ENST00000299697.7 ENST00000451102.2	TK2	thymidine kinase 2, mitochondrial
chr16_+_14802801	0.63	ENST00000526520.1 ENST00000531598.2	NPIPA3	nuclear pore complex interacting protein family, member A3
chr7_+_93551011	0.63	ENST00000248564.5	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr18_+_61254534	0.63	ENST00000269489.5	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr7_+_107220660	0.61	ENST00000465919.1 ENST00000445771.2 ENST00000479917.1 ENST00000421217.1 ENST00000457837.1	BCAP29	B-cell receptor-associated protein 29
chr20_+_11898507	0.60	ENST00000378226.2	BTBD3	BTB (POZ) domain containing 3
chr10_-_79397740	0.59	ENST00000372440.1 ENST00000480683.1	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_43424500	0.58	ENST00000415851.2 ENST00000426263.3 ENST00000372500.3	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr16_-_29517141	0.58	ENST00000550665.1	RP11-231C14.4	Uncharacterized protein
chr14_+_22458631	0.57	ENST00000390444.1	TRAV16	T cell receptor alpha variable 16
chr3_+_138066539	0.56	ENST00000289104.4	MRAS	muscle RAS oncogene homolog
chr4_-_57524061	0.56	ENST00000508121.1	HOPX	HOP homeobox
chr9_-_95244781	0.56	ENST00000375544.3 ENST00000375543.1 ENST00000395538.3 ENST00000450139.2	ASPN	asporin
chr2_+_130737223	0.55	ENST00000410061.2	RAB6C	RAB6C, member RAS oncogene family
chr1_-_21377447	0.55	ENST00000374937.3 ENST00000264211.8	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr6_+_53659746	0.55	ENST00000370888.1	LRRC1	leucine rich repeat containing 1
chr7_+_18535786	0.54	ENST00000406072.1	HDAC9	histone deacetylase 9
chr3_+_8543393	0.53	ENST00000157600.3 ENST00000415597.1 ENST00000535732.1	LMCD1	LIM and cysteine-rich domains 1
chr2_+_210517895	0.52	ENST00000447185.1	MAP2	microtubule-associated protein 2
chr12_+_26348429	0.52	ENST00000242729.2	SSPN	sarcospan
chr9_-_21351377	0.52	ENST00000380210.1	IFNA6	interferon, alpha 6
chr1_-_146082633	0.49	ENST00000605317.1 ENST00000604938.1 ENST00000339388.5	NBPF11	neuroblastoma breakpoint family, member 11
chr7_-_137028498	0.49	ENST00000393083.2	PTN	pleiotrophin
chr9_-_13279563	0.48	ENST00000541718.1	MPDZ	multiple PDZ domain protein
chr20_-_43150601	0.48	ENST00000541235.1 ENST00000255175.1 ENST00000342374.4	SERINC3	serine incorporator 3
chr1_-_149908217	0.47	ENST00000369140.3	MTMR11	myotubularin related protein 11
chr2_+_109237717	0.47	ENST00000409441.1	LIMS1	LIM and senescent cell antigen-like domains 1
chr16_-_18462221	0.46	ENST00000528301.1	RP11-1212A22.4	LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr1_-_6420737	0.45	ENST00000541130.1 ENST00000377845.3	ACOT7	acyl-CoA thioesterase 7
chr12_+_104609550	0.45	ENST00000525566.1 ENST00000429002.2	TXNRD1	thioredoxin reductase 1
chr15_+_71228826	0.45	ENST00000558456.1 ENST00000560158.2 ENST00000558808.1 ENST00000559806.1 ENST00000559069.1	LRRC49	leucine rich repeat containing 49
chr5_+_140797296	0.45	ENST00000398594.2	PCDHGB7	protocadherin gamma subfamily B, 7
chr11_-_118134997	0.43	ENST00000278937.2	MPZL2	myelin protein zero-like 2
chr12_-_27167233	0.42	ENST00000535819.1 ENST00000543803.1 ENST00000535423.1 ENST00000539741.1 ENST00000343028.4 ENST00000545600.1 ENST00000543088.1	TM7SF3	transmembrane 7 superfamily member 3
chr2_+_172544294	0.42	ENST00000358002.6 ENST00000435234.1 ENST00000443458.1 ENST00000412370.1	DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2
chr5_+_140734570	0.41	ENST00000571252.1	PCDHGA4	protocadherin gamma subfamily A, 4
chr15_+_72978539	0.41	ENST00000539603.1 ENST00000569338.1	BBS4	Bardet-Biedl syndrome 4
chr14_-_75643296	0.41	ENST00000303575.4	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr7_+_107220422	0.40	ENST00000005259.4	BCAP29	B-cell receptor-associated protein 29
chr1_-_21377383	0.40	ENST00000374935.3	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr2_-_74618964	0.40	ENST00000417090.1 ENST00000409868.1	DCTN1	dynactin 1
chr12_+_110011571	0.40	ENST00000539696.1 ENST00000228510.3 ENST00000392727.3	MVK	mevalonate kinase
chr16_+_28648975	0.40	ENST00000529716.1	NPIPB8	nuclear pore complex interacting protein family, member B8
chr5_+_147443534	0.39	ENST00000398454.1 ENST00000359874.3 ENST00000508733.1 ENST00000256084.7	SPINK5	serine peptidase inhibitor, Kazal type 5
chr16_+_22501658	0.39	ENST00000415833.2	NPIPB5	nuclear pore complex interacting protein family, member B5
chr15_+_72978521	0.39	ENST00000542334.1 ENST00000268057.4	BBS4	Bardet-Biedl syndrome 4
chr5_+_140792614	0.39	ENST00000398610.2	PCDHGA10	protocadherin gamma subfamily A, 10
chr18_-_61311485	0.38	ENST00000436264.1 ENST00000356424.6 ENST00000341074.5	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr10_-_79398127	0.38	ENST00000372443.1	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_11062161	0.38	ENST00000390677.2	TAS2R13	taste receptor, type 2, member 13
chr1_+_171283331	0.37	ENST00000367749.3	FMO4	flavin containing monooxygenase 4
chr4_+_177241094	0.37	ENST00000503362.1	SPCS3	signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr22_-_19466732	0.36	ENST00000263202.10 ENST00000360834.4	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr17_-_41174424	0.35	ENST00000355653.3	VAT1	vesicle amine transport 1
chr12_-_10151773	0.35	ENST00000298527.6 ENST00000348658.4	CLEC1B	C-type lectin domain family 1, member B
chr17_-_71410794	0.35	ENST00000424778.1	SDK2	sidekick cell adhesion molecule 2
chr22_+_45148432	0.34	ENST00000389774.2 ENST00000396119.2 ENST00000336963.4 ENST00000356099.6 ENST00000412433.1	ARHGAP8	Rho GTPase activating protein 8
chr1_-_165668100	0.34	ENST00000354775.4	ALDH9A1	aldehyde dehydrogenase 9 family, member A1
chr1_+_84630645	0.34	ENST00000394839.2	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr3_-_138763734	0.34	ENST00000413199.1 ENST00000502927.2	PRR23C	proline rich 23C
chr8_+_54764346	0.34	ENST00000297313.3 ENST00000344277.6	RGS20	regulator of G-protein signaling 20
chr11_-_86383650	0.33	ENST00000526944.1 ENST00000530335.1 ENST00000543262.1 ENST00000524826.1	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr4_+_492985	0.33	ENST00000296306.7 ENST00000536264.1 ENST00000310340.5 ENST00000453061.2 ENST00000504346.1 ENST00000503111.1 ENST00000383028.4 ENST00000509768.1	PIGG	phosphatidylinositol glycan anchor biosynthesis, class G
chr1_+_87012753	0.33	ENST00000370563.3	CLCA4	chloride channel accessory 4
chr13_-_33780133	0.33	ENST00000399365.3	STARD13	StAR-related lipid transfer (START) domain containing 13
chrX_-_104465358	0.33	ENST00000372578.3 ENST00000372575.1 ENST00000413579.1	TEX13A	testis expressed 13A
chr1_-_246729544	0.31	ENST00000544618.1 ENST00000366514.4	TFB2M	transcription factor B2, mitochondrial
chr22_-_38669030	0.31	ENST00000361906.3	TMEM184B	transmembrane protein 184B
chr12_+_123237321	0.31	ENST00000280557.6 ENST00000455982.2	DENR	density-regulated protein
chr1_-_153085984	0.31	ENST00000468739.1	SPRR2F	small proline-rich protein 2F
chr17_-_19266045	0.31	ENST00000395616.3	B9D1	B9 protein domain 1
chr19_-_47349395	0.31	ENST00000597020.1	AP2S1	adaptor-related protein complex 2, sigma 1 subunit
chr2_-_20251744	0.31	ENST00000175091.4	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr10_+_70748487	0.31	ENST00000361983.4	KIAA1279	KIAA1279
chr17_-_7145475	0.31	ENST00000571129.1 ENST00000571253.1 ENST00000573928.1	GABARAP	GABA(A) receptor-associated protein
chr4_-_69536346	0.31	ENST00000338206.5	UGT2B15	UDP glucuronosyltransferase 2 family, polypeptide B15
chr21_-_35884573	0.31	ENST00000399286.2	KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr1_-_203151933	0.31	ENST00000404436.2	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_153029980	0.31	ENST00000392653.2	SPRR2A	small proline-rich protein 2A
chr13_+_77564795	0.30	ENST00000377453.3	CLN5	ceroid-lipofuscinosis, neuronal 5
chr5_-_9630463	0.30	ENST00000382492.2	TAS2R1	taste receptor, type 2, member 1
chr1_+_196912902	0.30	ENST00000476712.2 ENST00000367415.5	CFHR2	complement factor H-related 2
chr5_-_55412774	0.30	ENST00000434982.2	ANKRD55	ankyrin repeat domain 55
chr3_-_151047327	0.29	ENST00000325602.5	P2RY13	purinergic receptor P2Y, G-protein coupled, 13
chr7_-_72993033	0.29	ENST00000305632.5	TBL2	transducin (beta)-like 2
chr5_+_140552218	0.29	ENST00000231137.3	PCDHB7	protocadherin beta 7
chr13_+_48611665	0.28	ENST00000258662.2	NUDT15	nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr4_+_169013666	0.28	ENST00000359299.3	ANXA10	annexin A10
chr12_-_10573149	0.28	ENST00000381904.2 ENST00000381903.2 ENST00000396439.2	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr22_-_19466683	0.28	ENST00000399523.1 ENST00000421968.2 ENST00000447868.1	UFD1L	ubiquitin fusion degradation 1 like (yeast)
chr3_+_189349162	0.28	ENST00000264731.3 ENST00000382063.4 ENST00000418709.2 ENST00000320472.5 ENST00000392460.3 ENST00000440651.2	TP63	tumor protein p63
chr9_+_35161998	0.27	ENST00000396787.1 ENST00000378495.3 ENST00000378496.4	UNC13B	unc-13 homolog B (C. elegans)
chr5_+_140474181	0.27	ENST00000194155.4	PCDHB2	protocadherin beta 2
chr22_+_51176624	0.27	ENST00000216139.5 ENST00000529621.1	ACR	acrosin
chr15_-_72523924	0.26	ENST00000566809.1 ENST00000567087.1 ENST00000569050.1 ENST00000568883.1	PKM	pyruvate kinase, muscle
chr12_-_10962767	0.26	ENST00000240691.2	TAS2R9	taste receptor, type 2, member 9
chr12_+_122326662	0.25	ENST00000261817.2 ENST00000538613.1 ENST00000542602.1	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr21_+_47531328	0.25	ENST00000409416.1 ENST00000397763.1	COL6A2	collagen, type VI, alpha 2
chr7_+_106505696	0.25	ENST00000440650.2 ENST00000496166.1 ENST00000473541.1	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr4_-_57547454	0.25	ENST00000556376.2	HOPX	HOP homeobox
chr17_-_66951474	0.25	ENST00000269080.2	ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8
chr4_+_95376396	0.25	ENST00000508216.1 ENST00000514743.1	PDLIM5	PDZ and LIM domain 5
chr17_-_3301704	0.25	ENST00000322608.2	OR1E1	olfactory receptor, family 1, subfamily E, member 1
chr8_-_141774467	0.24	ENST00000520151.1 ENST00000519024.1 ENST00000519465.1	PTK2	protein tyrosine kinase 2
chr16_-_28374829	0.24	ENST00000532254.1	NPIPB6	nuclear pore complex interacting protein family, member B6
chr2_-_74619152	0.24	ENST00000440727.1 ENST00000409240.1	DCTN1	dynactin 1
chr4_-_70518941	0.24	ENST00000286604.4 ENST00000505512.1 ENST00000514019.1	UGT2A1 UGT2A1	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr18_+_66465302	0.24	ENST00000360242.5 ENST00000358653.5	CCDC102B	coiled-coil domain containing 102B
chr15_-_78913521	0.24	ENST00000326828.5	CHRNA3	cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr10_-_92681033	0.24	ENST00000371697.3	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr12_-_71551652	0.23	ENST00000546561.1	TSPAN8	tetraspanin 8
chr20_+_123010	0.23	ENST00000382398.3	DEFB126	defensin, beta 126
chr5_-_93447333	0.23	ENST00000395965.3 ENST00000505869.1 ENST00000509163.1	FAM172A	family with sequence similarity 172, member A
chr3_+_8543533	0.23	ENST00000454244.1	LMCD1	LIM and cysteine-rich domains 1
chr2_+_90259593	0.23	ENST00000471857.1	IGKV1D-8	immunoglobulin kappa variable 1D-8
chr7_-_105752971	0.23	ENST00000011473.2	SYPL1	synaptophysin-like 1
chr19_+_9361606	0.23	ENST00000456448.1	OR7E24	olfactory receptor, family 7, subfamily E, member 24
chr20_-_10414804	0.23	ENST00000347364.3	MKKS	McKusick-Kaufman syndrome
chr17_-_2966901	0.23	ENST00000575751.1	OR1D5	olfactory receptor, family 1, subfamily D, member 5
chr6_-_136788001	0.23	ENST00000544465.1	MAP7	microtubule-associated protein 7
chr6_-_52705641	0.22	ENST00000370989.2	GSTA5	glutathione S-transferase alpha 5
chr15_-_89089860	0.22	ENST00000558413.1 ENST00000564406.1 ENST00000268148.8	DET1	de-etiolated homolog 1 (Arabidopsis)

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.5	GO:1990523	bone regeneration(GO:1990523)
0.7	2.2	GO:2000521	negative regulation of immunological synapse formation(GO:2000521)
0.6	2.4	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.6	1.8	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.5	5.4	GO:0001778	plasma membrane repair(GO:0001778)
0.4	1.5	GO:1904566	response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3	1.7	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.3	1.0	GO:0060296	regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3	3.8	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2	0.5	GO:1904397	negative regulation of neuromuscular junction development(GO:1904397)
0.2	2.1	GO:0043305	negative regulation of mast cell degranulation(GO:0043305)
0.2	1.4	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.2	2.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.6	GO:0070837	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) dehydroascorbic acid transport(GO:0070837)
0.2	0.8	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816) negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.2	2.0	GO:0034465	response to carbon monoxide(GO:0034465)
0.2	0.6	GO:0070171	negative regulation of tooth mineralization(GO:0070171)
0.2	4.1	GO:0003334	keratinocyte development(GO:0003334)
0.2	1.4	GO:1900623	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2	5.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.2	1.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.2	1.4	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2	0.6	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.2	1.5	GO:0051610	negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2	0.8	GO:0070980	biphenyl catabolic process(GO:0070980)
0.1	1.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1	0.4	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.1	0.4	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1	1.1	GO:0070836	caveola assembly(GO:0070836)
0.1	0.8	GO:0042426	choline catabolic process(GO:0042426)
0.1	0.5	GO:0036116	medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1	1.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.3	GO:0002188	translation reinitiation(GO:0002188)
0.1	0.4	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1	0.4	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.1	0.8	GO:0031444	slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1	0.3	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1	1.2	GO:0045919	positive regulation of cytolysis(GO:0045919)
0.1	2.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	1.7	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.6	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
0.1	0.3	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.4	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.1	0.8	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
0.1	0.3	GO:0010482	ectoderm and mesoderm interaction(GO:0007499) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1	0.3	GO:0097338	response to clozapine(GO:0097338)
0.1	0.3	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.5	GO:0009597	detection of virus(GO:0009597)
0.1	1.8	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.1	GO:0006788	heme oxidation(GO:0006788)
0.1	0.5	GO:0070933	peptidyl-lysine deacetylation(GO:0034983) histone H4 deacetylation(GO:0070933)
0.1	0.3	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.1	2.3	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1	0.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.1	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.8	GO:0070986	left/right axis specification(GO:0070986)
0.1	0.8	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.9	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.2	GO:0002933	lipid hydroxylation(GO:0002933)
0.1	0.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.6	GO:0097283	keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1	1.1	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.2	GO:0019605	benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.1	0.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1	0.3	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.1	0.3	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.4	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.4	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.3	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.7	GO:0031268	pseudopodium organization(GO:0031268)
0.0	1.5	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.2	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.2	GO:1902748	melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0	0.4	GO:2000580	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.8	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.8	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	1.2	GO:1901687	glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0	1.6	GO:0097435	fibril organization(GO:0097435)
0.0	0.3	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.7	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	1.2	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	4.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.8	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.0	1.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.1	GO:0010513	positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0	0.1	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:0038007	netrin-activated signaling pathway(GO:0038007)
0.0	0.2	GO:0050942	positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0	0.3	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
0.0	0.1	GO:0051066	dihydrobiopterin metabolic process(GO:0051066)
0.0	0.5	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.3	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0045014	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.2	GO:0035994	response to muscle stretch(GO:0035994)
0.0	1.7	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.1	GO:0071048	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0	1.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.3	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.8	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0	0.3	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.3	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.7	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	1.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.8	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.3	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.0	0.5	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of adherens junction organization(GO:1903393)
0.0	6.7	GO:0006936	muscle contraction(GO:0006936)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.2	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.0	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0	0.8	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.2	GO:0003301	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.6	GO:0042733	embryonic digit morphogenesis(GO:0042733)
0.0	0.0	GO:0008090	retrograde axonal transport(GO:0008090)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.5	2.3	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.3	4.3	GO:0030478	actin cap(GO:0030478)
0.3	3.8	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.4	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2	1.3	GO:0005610	laminin-5 complex(GO:0005610)
0.1	0.1	GO:0005712	chiasma(GO:0005712)
0.1	0.3	GO:0044305	calyx of Held(GO:0044305)
0.1	0.8	GO:0034464	BBSome(GO:0034464)
0.1	3.7	GO:0045095	keratin filament(GO:0045095)
0.1	3.0	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.5	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	0.3	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	4.3	GO:0002102	podosome(GO:0002102)
0.1	0.6	GO:0001939	female pronucleus(GO:0001939)
0.1	8.8	GO:0005901	caveola(GO:0005901)
0.1	0.2	GO:1902636	kinociliary basal body(GO:1902636)
0.1	1.6	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.1	0.8	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.2	GO:0032433	filopodium tip(GO:0032433)
0.1	0.4	GO:0097209	epidermal lamellar body(GO:0097209)
0.1	0.4	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.8	GO:0005652	nuclear lamina(GO:0005652)
0.1	1.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	1.6	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.4	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.6	GO:0005869	dynactin complex(GO:0005869)
0.0	0.8	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	2.9	GO:0031594	neuromuscular junction(GO:0031594)
0.0	2.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	1.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.8	GO:0005861	troponin complex(GO:0005861)
0.0	0.5	GO:0036038	MKS complex(GO:0036038)
0.0	1.6	GO:0031430	M band(GO:0031430)
0.0	0.7	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	1.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.5	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.4	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	2.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0044853	plasma membrane raft(GO:0044853)
0.0	0.1	GO:0043564	Ku70:Ku80 complex(GO:0043564)
0.0	0.1	GO:0071020	post-spliceosomal complex(GO:0071020)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.8	GO:0001533	cornified envelope(GO:0001533)
0.0	0.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.3	GO:0036020	endolysosome membrane(GO:0036020)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0032797	SMN complex(GO:0032797)
0.0	1.1	GO:0036126	sperm flagellum(GO:0036126)
0.0	0.1	GO:0072589	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.1	GO:0005657	replication fork(GO:0005657)
0.0	0.1	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	1.1	GO:0042641	actomyosin(GO:0042641)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.8	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.0	GO:0031673	H zone(GO:0031673)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.5	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	5.9	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	4.0	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	5.8	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	1.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.9	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.4	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.6	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	1.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.8	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	2.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.6	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	PID CDC42 PATHWAY	CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.4	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	5.6	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	2.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.2	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	2.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	1.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.8	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	1.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	2.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.8	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	2.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.5	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.8	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.8	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.7	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.0	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.4	1.5	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3	2.2	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.3	2.0	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.3	2.2	GO:0019863	IgE binding(GO:0019863)
0.3	1.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.9	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.2	1.1	GO:0004771	sterol esterase activity(GO:0004771)
0.2	0.6	GO:0004797	deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.2	0.6	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.2	5.1	GO:0005523	tropomyosin binding(GO:0005523)
0.2	4.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	1.5	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.2	1.8	GO:0033038	bitter taste receptor activity(GO:0033038)
0.2	1.8	GO:0008430	selenium binding(GO:0008430)
0.1	0.4	GO:0098625	methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.1	1.2	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.1	0.5	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	2.3	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.1	0.3	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1	0.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) NADH pyrophosphatase activity(GO:0035529) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.1	2.3	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1	0.3	GO:0004040	amidase activity(GO:0004040) fucose binding(GO:0042806)
0.1	0.9	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	0.3	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	0.4	GO:0008948	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.1	0.3	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.1	0.8	GO:0034452	dynactin binding(GO:0034452)
0.1	0.6	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.3	GO:0004743	pyruvate kinase activity(GO:0004743)
0.1	0.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	0.8	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.9	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	1.5	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.9	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	3.9	GO:0097110	scaffold protein binding(GO:0097110)
0.0	1.1	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	1.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.5	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.0	0.3	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0	0.9	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.8	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.5	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	1.8	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	4.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	1.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.2	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	3.9	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.5	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0033149	FFAT motif binding(GO:0033149)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.1	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.0	0.1	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) azole transmembrane transporter activity(GO:1901474)
0.0	1.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.3	GO:0008061	chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.0	0.7	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.8	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.8	GO:0001671	ATPase activator activity(GO:0001671)
0.0	1.7	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.2	GO:0042731	PH domain binding(GO:0042731)
0.0	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0	0.5	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	1.6	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0000386	second spliceosomal transesterification activity(GO:0000386)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.3	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690) cGMP-dependent protein kinase activity(GO:0004692)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0070404	NADH binding(GO:0070404)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.7	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.3	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.1	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0	0.1	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.6	GO:0031625	ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0	0.0	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.1	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0019237	satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.0	1.8	GO:0008201	heparin binding(GO:0008201)
0.0	1.5	GO:0005178	integrin binding(GO:0005178)