Project

ENCODE cell lines, expression (Ernst 2011)

Navigation
Downloads

Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 0.67

Motif logo

logo of logo of logo of

Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
BHLHE22
ENSG00000180828.1 BHLHE22
BHLHA15
ENSG00000180535.3 BHLHA15
BHLHE23
ENSG00000125533.4 BHLHE23

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_111312622 2.92 ENST00000395634.3
 NREP
 neuronal regeneration related protein
chr3_-_121379739 2.65 ENST00000428394.2
ENST00000314583.3
 HCLS1
 hematopoietic cell-specific Lyn substrate 1
chr3_-_114477962 1.94 ENST00000471418.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr3_-_114477787 1.88 ENST00000464560.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr2_-_188378368 1.65 ENST00000392365.1
ENST00000435414.1
 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_-_27205136 1.25 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr1_+_244214577 0.71 ENST00000358704.4
 ZBTB18
 zinc finger and BTB domain containing 18
chr6_-_112115074 0.70 ENST00000368667.2
 FYN
 FYN oncogene related to SRC, FGR, YES
chr11_+_65405556 0.63 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
 SIPA1
 signal-induced proliferation-associated 1
chr18_-_52989525 0.60 ENST00000457482.3
 TCF4
 transcription factor 4
chrX_+_128913906 0.59 ENST00000356892.3
 SASH3
 SAM and SH3 domain containing 3
chr4_-_159094194 0.59 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
 FAM198B
 family with sequence similarity 198, member B
chr7_+_116502605 0.54 ENST00000458284.2
ENST00000490693.1
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr15_-_55700522 0.48 ENST00000564092.1
ENST00000310958.6
 CCPG1
 cell cycle progression 1
chr16_+_31119615 0.45 ENST00000394950.3
ENST00000287507.3
ENST00000219794.6
ENST00000561755.1
 BCKDK
 branched chain ketoacid dehydrogenase kinase
chr4_-_41216619 0.40 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
chr15_-_55700216 0.37 ENST00000569205.1
 CCPG1
 cell cycle progression 1
chr10_-_75415825 0.27 ENST00000394810.2
 SYNPO2L
 synaptopodin 2-like
chr3_+_62304648 0.27 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
 C3orf14
 chromosome 3 open reading frame 14
chr15_-_55700457 0.27 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
 CCPG1
 cell cycle progression 1
chr7_+_116502527 0.26 ENST00000361183.3
 CAPZA2
 capping protein (actin filament) muscle Z-line, alpha 2
chr15_-_63448973 0.26 ENST00000462430.1
 RPS27L
 ribosomal protein S27-like
chr12_-_91573249 0.25 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr15_+_63354769 0.25 ENST00000558910.1
 TPM1
 tropomyosin 1 (alpha)
chr12_-_91573316 0.24 ENST00000393155.1
 DCN
 decorin
chr12_-_91573132 0.24 ENST00000550563.1
ENST00000546370.1
 DCN
 decorin
chrX_+_107334895 0.24 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
 ATG4A
 autophagy related 4A, cysteine peptidase
chr14_-_69864993 0.22 ENST00000555373.1
 ERH
 enhancer of rudimentary homolog (Drosophila)
chr17_+_60758814 0.20 ENST00000579432.1
ENST00000446119.2
 MRC2
 mannose receptor, C type 2
chr11_-_107582775 0.17 ENST00000305991.2
 SLN
 sarcolipin
chr8_-_23315190 0.17 ENST00000356206.6
ENST00000358689.4
ENST00000417069.2
 ENTPD4
 ectonucleoside triphosphate diphosphohydrolase 4
chr9_-_130635741 0.17 ENST00000223836.10
 AK1
 adenylate kinase 1
chr9_+_2158443 0.15 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr9_+_2158485 0.15 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_113251143 0.14 ENST00000264852.4
ENST00000393830.3
 SIDT1
 SID1 transmembrane family, member 1
chr12_-_108714412 0.14 ENST00000412676.1
ENST00000550573.1
 CMKLR1
 chemokine-like receptor 1
chr2_-_163099885 0.13 ENST00000443424.1
 FAP
 fibroblast activation protein, alpha
chr7_-_55930443 0.12 ENST00000388975.3
 SEPT14
 septin 14
chr11_-_26743546 0.12 ENST00000280467.6
ENST00000396005.3
 SLC5A12
 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr4_+_2814011 0.12 ENST00000502260.1
ENST00000435136.2
 SH3BP2
 SH3-domain binding protein 2
chr3_+_171758344 0.12 ENST00000336824.4
ENST00000423424.1
 FNDC3B
 fibronectin type III domain containing 3B
chr7_-_38403077 0.11 ENST00000426402.2
 TRGV2
 T cell receptor gamma variable 2
chr10_+_18629628 0.10 ENST00000377329.4
 CACNB2
 calcium channel, voltage-dependent, beta 2 subunit
chr10_-_94257512 0.10 ENST00000371581.5
 IDE
 insulin-degrading enzyme
chr4_+_2813946 0.10 ENST00000442312.2
 SH3BP2
 SH3-domain binding protein 2
chr19_-_11450249 0.09 ENST00000222120.3
 RAB3D
 RAB3D, member RAS oncogene family
chr12_-_102872317 0.09 ENST00000424202.2
 IGF1
 insulin-like growth factor 1 (somatomedin C)
chr11_-_44972476 0.08 ENST00000527685.1
ENST00000308212.5
 TP53I11
 tumor protein p53 inducible protein 11
chr6_+_163148161 0.08 ENST00000337019.3
ENST00000366889.2
 PACRG
 PARK2 co-regulated
chr4_+_144354644 0.08 ENST00000512843.1
 GAB1
 GRB2-associated binding protein 1
chr14_+_69865401 0.08 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
 SLC39A9
 solute carrier family 39, member 9
chrX_-_13835147 0.08 ENST00000493677.1
ENST00000355135.2
 GPM6B
 glycoprotein M6B
chr2_+_219110149 0.08 ENST00000456575.1
 ARPC2
 actin related protein 2/3 complex, subunit 2, 34kDa
chr11_+_66008698 0.08 ENST00000531597.1
 PACS1
 phosphofurin acidic cluster sorting protein 1
chr15_-_65503801 0.07 ENST00000261883.4
 CILP
 cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_+_104293028 0.06 ENST00000370079.3
 AMY1C
 amylase, alpha 1C (salivary)
chr2_-_163100045 0.06 ENST00000188790.4
 FAP
 fibroblast activation protein, alpha
chrX_+_107288239 0.05 ENST00000217957.5
 VSIG1
 V-set and immunoglobulin domain containing 1
chr19_+_57874835 0.05 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
 TRAPPC2P1
ZNF547
AC003002.4
 trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr6_+_73076432 0.04 ENST00000414192.2
 RIMS1
 regulating synaptic membrane exocytosis 1
chr12_+_58166370 0.04 ENST00000300209.8
 METTL21B
 methyltransferase like 21B
chr8_-_67976509 0.03 ENST00000518747.1
 COPS5
 COP9 signalosome subunit 5
chr7_+_107531580 0.03 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
 DLD
 dihydrolipoamide dehydrogenase
chrX_+_107288197 0.03 ENST00000415430.3
 VSIG1
 V-set and immunoglobulin domain containing 1
chr10_-_74114714 0.03 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
chr5_-_171433819 0.02 ENST00000296933.6
 FBXW11
 F-box and WD repeat domain containing 11
chrX_-_15402498 0.02 ENST00000297904.3
 FIGF
 c-fos induced growth factor (vascular endothelial growth factor D)
chr2_+_210444748 0.02 ENST00000392194.1
 MAP2
 microtubule-associated protein 2
chr1_-_44818599 0.02 ENST00000537474.1
 ERI3
 ERI1 exoribonuclease family member 3
chr5_-_171433579 0.02 ENST00000265094.5
ENST00000393802.2
 FBXW11
 F-box and WD repeat domain containing 11
chr11_-_44972418 0.02 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
 TP53I11
 tumor protein p53 inducible protein 11
chr22_+_36113919 0.02 ENST00000249044.2
 APOL5
 apolipoprotein L, 5
chr19_-_52227221 0.02 ENST00000222115.1
ENST00000540069.2
 HAS1
 hyaluronan synthase 1
chr12_+_58166431 0.02 ENST00000333012.5
 METTL21B
 methyltransferase like 21B
chrX_+_69509927 0.02 ENST00000374403.3
 KIF4A
 kinesin family member 4A
chr1_+_186344883 0.01 ENST00000367470.3
 C1orf27
 chromosome 1 open reading frame 27
chr16_-_4896205 0.01 ENST00000589389.1
 GLYR1
 glyoxylate reductase 1 homolog (Arabidopsis)
chr3_+_119298429 0.01 ENST00000478927.1
 ADPRH
 ADP-ribosylarginine hydrolase
chr5_-_169725231 0.01 ENST00000046794.5
 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_-_107283278 0.00 ENST00000390639.2
 IGHV7-81
 immunoglobulin heavy variable 7-81 (non-functional)

Gene Ontology Analysis

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 2.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.6 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.2 GO:0051697 protein delipidation(GO:0051697)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.8 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)