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ENCODE cell lines, expression (Ernst 2011)

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Results for CAGUAGU

Z-value: 0.78

Motif logo

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miRNA associated with seed CAGUAGU

NamemiRBASE accession
hsa-miR-199a-3p
MIMAT0000232
hsa-miR-199b-3p
MIMAT0004563
hsa-miR-3129-5p
MIMAT0014992

Activity profile of CAGUAGU motif

Sorted Z-values of CAGUAGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CAGUAGU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_224903995 2.98 ENST00000409304.1
ENST00000454956.1
ENST00000258405.4
 SERPINE2
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr20_-_14318248 1.59 ENST00000378053.3
ENST00000341420.4
 FLRT3
 fibronectin leucine rich transmembrane protein 3
chr3_-_98620500 1.57 ENST00000326840.6
 DCBLD2
 discoidin, CUB and LCCL domain containing 2
chr1_-_57045228 1.42 ENST00000371250.3
 PPAP2B
 phosphatidic acid phosphatase type 2B
chr6_+_53659746 1.33 ENST00000370888.1
 LRRC1
 leucine rich repeat containing 1
chr2_+_36582857 1.30 ENST00000280527.2
 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr7_-_19157248 1.23 ENST00000242261.5
 TWIST1
 twist family bHLH transcription factor 1
chr5_-_172756506 1.17 ENST00000265087.4
 STC2
 stanniocalcin 2
chr2_+_110371905 1.15 ENST00000356454.3
 SOWAHC
 sosondowah ankyrin repeat domain family member C
chr7_-_95064264 1.09 ENST00000536183.1
ENST00000433091.2
ENST00000222572.3
 PON2
 paraoxonase 2
chr11_+_101981169 0.95 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
 YAP1
 Yes-associated protein 1
chr2_+_148602058 0.94 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
 ACVR2A
 activin A receptor, type IIA
chr2_+_173292301 0.92 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
 ITGA6
 integrin, alpha 6
chr3_+_61547585 0.89 ENST00000295874.10
ENST00000474889.1
 PTPRG
 protein tyrosine phosphatase, receptor type, G
chr11_+_35160709 0.87 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
 CD44
 CD44 molecule (Indian blood group)
chr1_-_94079648 0.87 ENST00000370247.3
 BCAR3
 breast cancer anti-estrogen resistance 3
chr15_-_56209306 0.85 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr3_+_110790590 0.84 ENST00000485303.1
 PVRL3
 poliovirus receptor-related 3
chr2_-_216300784 0.69 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
 FN1
 fibronectin 1
chr11_+_832944 0.69 ENST00000322008.4
ENST00000397421.1
ENST00000529810.1
ENST00000526693.1
ENST00000525333.1
ENST00000524748.1
ENST00000527341.1
 CD151
 CD151 molecule (Raph blood group)
chr5_-_121413974 0.67 ENST00000231004.4
 LOX
 lysyl oxidase
chr11_+_12695944 0.63 ENST00000361905.4
 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr12_-_77272765 0.61 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
 CSRP2
 cysteine and glycine-rich protein 2
chr12_-_80084862 0.61 ENST00000328827.4
 PAWR
 PRKC, apoptosis, WT1, regulator
chr8_+_123793633 0.58 ENST00000314393.4
 ZHX2
 zinc fingers and homeoboxes 2
chr1_+_7831323 0.56 ENST00000054666.6
 VAMP3
 vesicle-associated membrane protein 3
chr3_-_114790179 0.54 ENST00000462705.1
 ZBTB20
 zinc finger and BTB domain containing 20
chr14_-_52535712 0.53 ENST00000216286.5
ENST00000541773.1
 NID2
 nidogen 2 (osteonidogen)
chr5_-_16936340 0.51 ENST00000507288.1
ENST00000513610.1
 MYO10
 myosin X
chr2_-_106810783 0.48 ENST00000283148.7
 UXS1
 UDP-glucuronate decarboxylase 1
chr6_-_139695757 0.48 ENST00000367651.2
 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr8_-_42397037 0.45 ENST00000342228.3
 SLC20A2
 solute carrier family 20 (phosphate transporter), member 2
chr11_+_129939779 0.45 ENST00000533195.1
ENST00000533713.1
ENST00000528499.1
ENST00000539648.1
ENST00000263574.5
 APLP2
 amyloid beta (A4) precursor-like protein 2
chr15_+_33010175 0.44 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
 GREM1
 gremlin 1, DAN family BMP antagonist
chr3_-_69435224 0.44 ENST00000398540.3
 FRMD4B
 FERM domain containing 4B
chr7_+_116139424 0.42 ENST00000222693.4
 CAV2
 caveolin 2
chr9_+_2621798 0.40 ENST00000382100.3
 VLDLR
 very low density lipoprotein receptor
chr10_+_74033672 0.38 ENST00000307365.3
 DDIT4
 DNA-damage-inducible transcript 4
chrX_-_8700171 0.38 ENST00000262648.3
 KAL1
 Kallmann syndrome 1 sequence
chr2_-_47168906 0.37 ENST00000444761.2
ENST00000409147.1
 MCFD2
 multiple coagulation factor deficiency 2
chrX_+_78003204 0.36 ENST00000435339.3
ENST00000514744.1
 LPAR4
 lysophosphatidic acid receptor 4
chr10_+_92980517 0.33 ENST00000336126.5
 PCGF5
 polycomb group ring finger 5
chr6_+_158733692 0.32 ENST00000367094.2
ENST00000367097.3
 TULP4
 tubby like protein 4
chrX_+_107683096 0.31 ENST00000328300.6
ENST00000361603.2
 COL4A5
 collagen, type IV, alpha 5
chr21_-_36260980 0.31 ENST00000344691.4
ENST00000358356.5
 RUNX1
 runt-related transcription factor 1
chr1_+_162602244 0.30 ENST00000367922.3
ENST00000367921.3
 DDR2
 discoidin domain receptor tyrosine kinase 2
chr12_-_120687948 0.30 ENST00000458477.2
 PXN
 paxillin
chr3_+_137906109 0.29 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
 ARMC8
 armadillo repeat containing 8
chr15_-_34502278 0.29 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
 KATNBL1
 katanin p80 subunit B-like 1
chr2_-_208030647 0.29 ENST00000309446.6
 KLF7
 Kruppel-like factor 7 (ubiquitous)
chr10_+_20105157 0.29 ENST00000377242.3
ENST00000377252.4
 PLXDC2
 plexin domain containing 2
chr1_+_29563011 0.29 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
 PTPRU
 protein tyrosine phosphatase, receptor type, U
chr4_-_129208940 0.29 ENST00000296425.5
 PGRMC2
 progesterone receptor membrane component 2
chr5_-_148930960 0.28 ENST00000261798.5
ENST00000377843.2
 CSNK1A1
 casein kinase 1, alpha 1
chr15_-_77363513 0.27 ENST00000267970.4
 TSPAN3
 tetraspanin 3
chr9_-_107690420 0.26 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
 ABCA1
 ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_128379346 0.25 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
 CALU
 calumenin
chr10_+_5454505 0.25 ENST00000355029.4
 NET1
 neuroepithelial cell transforming 1
chr2_+_138721850 0.25 ENST00000329366.4
ENST00000280097.3
 HNMT
 histamine N-methyltransferase
chr1_+_65613217 0.24 ENST00000545314.1
 AK4
 adenylate kinase 4
chr2_+_46524537 0.23 ENST00000263734.3
 EPAS1
 endothelial PAS domain protein 1
chr9_-_23821273 0.23 ENST00000380110.4
 ELAVL2
 ELAV like neuron-specific RNA binding protein 2
chr7_-_129592700 0.23 ENST00000472396.1
ENST00000355621.3
 UBE2H
 ubiquitin-conjugating enzyme E2H
chr11_+_33278811 0.21 ENST00000303296.4
ENST00000379016.3
 HIPK3
 homeodomain interacting protein kinase 3
chr3_+_38495333 0.21 ENST00000352511.4
 ACVR2B
 activin A receptor, type IIB
chr3_-_11762202 0.21 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
 VGLL4
 vestigial like 4 (Drosophila)
chr9_+_125703282 0.20 ENST00000373647.4
ENST00000402311.1
 RABGAP1
 RAB GTPase activating protein 1
chr6_+_89790490 0.20 ENST00000336032.3
 PNRC1
 proline-rich nuclear receptor coactivator 1
chr1_+_109792641 0.20 ENST00000271332.3
 CELSR2
 cadherin, EGF LAG seven-pass G-type receptor 2
chr1_+_244214577 0.20 ENST00000358704.4
 ZBTB18
 zinc finger and BTB domain containing 18
chr3_-_56835967 0.19 ENST00000495373.1
ENST00000296315.3
 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
chr7_-_27205136 0.19 ENST00000396345.1
ENST00000343483.6
 HOXA9
 homeobox A9
chr21_+_46494466 0.19 ENST00000539173.1
ENST00000389863.4
ENST00000348831.4
ENST00000437626.1
 ADARB1
 adenosine deaminase, RNA-specific, B1
chr10_-_105615164 0.19 ENST00000355946.2
ENST00000369774.4
 SH3PXD2A
 SH3 and PX domains 2A
chr19_+_41222998 0.18 ENST00000263370.2
 ITPKC
 inositol-trisphosphate 3-kinase C
chr7_+_99613195 0.18 ENST00000324306.6
 ZKSCAN1
 zinc finger with KRAB and SCAN domains 1
chr9_+_129567282 0.17 ENST00000449886.1
ENST00000373464.4
ENST00000450858.1
 ZBTB43
 zinc finger and BTB domain containing 43
chr2_-_37899323 0.16 ENST00000295324.3
ENST00000457889.1
 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
chr16_+_67880574 0.16 ENST00000219169.4
 NUTF2
 nuclear transport factor 2
chr12_-_16761007 0.16 ENST00000354662.1
ENST00000441439.2
 LMO3
 LIM domain only 3 (rhombotin-like 2)
chr20_-_4982132 0.16 ENST00000338244.1
ENST00000424750.2
 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
chr5_-_179780312 0.16 ENST00000253778.8
 GFPT2
 glutamine-fructose-6-phosphate transaminase 2
chr14_+_75745477 0.15 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
 FOS
 FBJ murine osteosarcoma viral oncogene homolog
chr3_+_107241783 0.14 ENST00000415149.2
ENST00000402543.1
ENST00000325805.8
ENST00000427402.1
 BBX
 bobby sox homolog (Drosophila)
chr13_-_30169807 0.13 ENST00000380752.5
 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr2_+_42396472 0.11 ENST00000318522.5
ENST00000402711.2
 EML4
 echinoderm microtubule associated protein like 4
chr1_-_19578003 0.11 ENST00000375199.3
ENST00000375208.3
ENST00000356068.2
ENST00000477853.1
 EMC1
 ER membrane protein complex subunit 1
chr16_-_71758602 0.11 ENST00000568954.1
 PHLPP2
 PH domain and leucine rich repeat protein phosphatase 2
chr7_-_2883928 0.11 ENST00000275364.3
 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
chr17_-_1303462 0.11 ENST00000573026.1
ENST00000575977.1
ENST00000571732.1
ENST00000264335.8
 YWHAE
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
chrX_+_40944871 0.11 ENST00000378308.2
ENST00000324545.8
 USP9X
 ubiquitin specific peptidase 9, X-linked
chr3_+_38206975 0.11 ENST00000446845.1
ENST00000311806.3
 OXSR1
 oxidative stress responsive 1
chr11_+_120207787 0.11 ENST00000397843.2
ENST00000356641.3
 ARHGEF12
 Rho guanine nucleotide exchange factor (GEF) 12
chr10_-_28571015 0.10 ENST00000375719.3
ENST00000375732.1
 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr14_-_100070363 0.10 ENST00000380243.4
 CCDC85C
 coiled-coil domain containing 85C
chrX_+_117861535 0.10 ENST00000371666.3
ENST00000371642.1
 IL13RA1
 interleukin 13 receptor, alpha 1
chr3_+_37284668 0.09 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
 GOLGA4
 golgin A4
chr12_-_57030115 0.09 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
 BAZ2A
 bromodomain adjacent to zinc finger domain, 2A
chr15_+_41523335 0.09 ENST00000334660.5
 CHP1
 calcineurin-like EF-hand protein 1
chr7_-_76829125 0.08 ENST00000248598.5
 FGL2
 fibrinogen-like 2
chr15_+_84322827 0.08 ENST00000286744.5
ENST00000567476.1
 ADAMTSL3
 ADAMTS-like 3
chr19_+_4969116 0.08 ENST00000588337.1
ENST00000159111.4
ENST00000381759.4
 KDM4B
 lysine (K)-specific demethylase 4B
chr19_+_1205740 0.07 ENST00000326873.7
 STK11
 serine/threonine kinase 11
chr6_+_7107999 0.07 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
 RREB1
 ras responsive element binding protein 1
chr14_+_23067146 0.07 ENST00000428304.2
 ABHD4
 abhydrolase domain containing 4
chr1_-_52344471 0.07 ENST00000352171.7
ENST00000354831.7
 NRD1
 nardilysin (N-arginine dibasic convertase)
chr16_+_58549378 0.06 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
 SETD6
 SET domain containing 6
chr5_-_171433819 0.06 ENST00000296933.6
 FBXW11
 F-box and WD repeat domain containing 11
chr10_+_112257596 0.06 ENST00000369583.3
 DUSP5
 dual specificity phosphatase 5
chr8_+_67579807 0.06 ENST00000519289.1
ENST00000519561.1
ENST00000521889.1
 C8orf44-SGK3
C8orf44
 C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr15_+_31619013 0.06 ENST00000307145.3
 KLF13
 Kruppel-like factor 13
chr1_-_36022979 0.05 ENST00000469892.1
ENST00000325722.3
 KIAA0319L
 KIAA0319-like
chr9_-_95432536 0.05 ENST00000287996.3
 IPPK
 inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr12_+_56401268 0.05 ENST00000262032.5
 IKZF4
 IKAROS family zinc finger 4 (Eos)
chr12_-_46662772 0.05 ENST00000549049.1
ENST00000439706.1
ENST00000398637.5
 SLC38A1
 solute carrier family 38, member 1
chrX_-_77041685 0.05 ENST00000373344.5
ENST00000395603.3
 ATRX
 alpha thalassemia/mental retardation syndrome X-linked
chr4_+_123747834 0.05 ENST00000264498.3
 FGF2
 fibroblast growth factor 2 (basic)
chr8_-_74791051 0.05 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
 UBE2W
 ubiquitin-conjugating enzyme E2W (putative)
chrX_-_77150985 0.05 ENST00000358075.6
 MAGT1
 magnesium transporter 1
chrX_-_130037198 0.05 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
 ENOX2
 ecto-NOX disulfide-thiol exchanger 2
chr2_-_213403565 0.05 ENST00000342788.4
ENST00000436443.1
 ERBB4
 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr3_+_180630090 0.05 ENST00000357559.4
ENST00000305586.7
 FXR1
 fragile X mental retardation, autosomal homolog 1
chr13_+_48877895 0.05 ENST00000267163.4
 RB1
 retinoblastoma 1
chr2_-_73053126 0.05 ENST00000272427.6
ENST00000410104.1
 EXOC6B
 exocyst complex component 6B
chr16_-_75498553 0.05 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
 TMEM170A
RP11-77K12.1
 transmembrane protein 170A
Uncharacterized protein
chr4_+_148538517 0.04 ENST00000296582.3
ENST00000508208.1
 TMEM184C
 transmembrane protein 184C
chr17_+_73521763 0.04 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
chr17_+_36508111 0.04 ENST00000331159.5
ENST00000577233.1
 SOCS7
 suppressor of cytokine signaling 7
chr11_+_111473108 0.04 ENST00000304987.3
 SIK2
 salt-inducible kinase 2
chr15_-_56535464 0.03 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
 RFX7
 regulatory factor X, 7
chr12_+_862089 0.03 ENST00000315939.6
ENST00000537687.1
ENST00000447667.2
 WNK1
 WNK lysine deficient protein kinase 1
chr17_+_34900737 0.03 ENST00000304718.4
ENST00000485685.2
 GGNBP2
 gametogenetin binding protein 2
chr3_-_105587879 0.03 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
chrX_+_133507327 0.02 ENST00000332070.3
ENST00000394292.1
ENST00000370799.1
ENST00000416404.2
 PHF6
 PHD finger protein 6
chr5_+_52083730 0.02 ENST00000282588.6
ENST00000274311.2
 ITGA1
PELO
 integrin, alpha 1
pelota homolog (Drosophila)
chr1_+_87170247 0.02 ENST00000370558.4
 SH3GLB1
 SH3-domain GRB2-like endophilin B1
chr4_-_74124502 0.02 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
 ANKRD17
 ankyrin repeat domain 17
chr10_-_126432619 0.02 ENST00000337318.3
 FAM53B
 family with sequence similarity 53, member B
chr13_+_32605437 0.02 ENST00000380250.3
 FRY
 furry homolog (Drosophila)
chr15_+_49715293 0.02 ENST00000267843.4
ENST00000560270.1
 FGF7
 fibroblast growth factor 7
chr12_+_62860581 0.01 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
 MON2
 MON2 homolog (S. cerevisiae)
chrX_+_76709648 0.01 ENST00000439435.1
 FGF16
 fibroblast growth factor 16
chr1_+_224301787 0.01 ENST00000366862.5
ENST00000424254.2
 FBXO28
 F-box protein 28
chr1_-_177133818 0.01 ENST00000424564.2
ENST00000361833.2
 ASTN1
 astrotactin 1
chr9_+_77112244 0.00 ENST00000376896.3
 RORB
 RAR-related orphan receptor B
chr7_-_83824169 0.00 ENST00000265362.4
 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_15767971 0.00 ENST00000479740.1
ENST00000454127.2
 CA5B
 carbonic anhydrase VB, mitochondrial

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0061107 seminal vesicle development(GO:0061107)
0.4 1.2 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 0.7 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 0.8 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.2 0.9 GO:0042713 sperm ejaculation(GO:0042713)
0.2 0.6 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:1900158 negative regulation of osteoclast proliferation(GO:0090291) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.5 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.9 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.6 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.4 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.9 GO:0010668 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.1 0.3 GO:0090107 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 1.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.6 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.8 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.4 GO:0045820 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.6 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.5 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.0 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.6 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.0 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0038025 glycoprotein transporter activity(GO:0034437) reelin receptor activity(GO:0038025)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.9 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 3.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 1.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 1.6 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.3 0.9 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.2 0.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway