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ENCODE cell lines, expression (Ernst 2011)

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Results for CDC5L

Z-value: 1.08

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Transcription factors associated with CDC5L

Gene Symbol Gene ID Gene Info
CDC5L
ENSG00000096401.7 CDC5L

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDC5Lhg19_v2_chr6_+_44355257_443553150.292.8e-01Click!

Activity profile of CDC5L motif

Sorted Z-values of CDC5L motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CDC5L

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_+_127413481 3.22 ENST00000259254.4
 GYPC
 glycophorin C (Gerbich blood group)
chr6_-_49604545 2.02 ENST00000371175.4
ENST00000229810.7
 RHAG
 Rh-associated glycoprotein
chr1_+_198608146 1.48 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
 PTPRC
 protein tyrosine phosphatase, receptor type, C
chr15_-_55562582 1.43 ENST00000396307.2
 RAB27A
 RAB27A, member RAS oncogene family
chr15_-_55562479 1.42 ENST00000564609.1
 RAB27A
 RAB27A, member RAS oncogene family
chr12_-_53601055 1.31 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
 ITGB7
 integrin, beta 7
chr6_-_32557610 1.26 ENST00000360004.5
 HLA-DRB1
 major histocompatibility complex, class II, DR beta 1
chr15_-_55611306 1.14 ENST00000563262.1
 RAB27A
 RAB27A, member RAS oncogene family
chr5_+_118690466 1.12 ENST00000503646.1
 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
chr6_+_13182751 1.11 ENST00000415087.1
 PHACTR1
 phosphatase and actin regulator 1
chr12_-_53601000 1.04 ENST00000338737.4
ENST00000549086.2
 ITGB7
 integrin, beta 7
chr11_+_59824060 1.03 ENST00000395032.2
ENST00000358152.2
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr7_+_116654935 1.02 ENST00000432298.1
ENST00000422922.1
 ST7
 suppression of tumorigenicity 7
chrX_+_52780318 0.99 ENST00000375515.3
ENST00000276049.6
 SSX2B
 synovial sarcoma, X breakpoint 2B
chrX_+_65382433 0.99 ENST00000374727.3
 HEPH
 hephaestin
chr8_+_99956662 0.99 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
 OSR2
 odd-skipped related transciption factor 2
chr6_-_32498046 0.98 ENST00000374975.3
 HLA-DRB5
 major histocompatibility complex, class II, DR beta 5
chr11_+_59824127 0.97 ENST00000278865.3
 MS4A3
 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr6_+_32812568 0.95 ENST00000414474.1
 PSMB9
 proteasome (prosome, macropain) subunit, beta type, 9
chr16_+_33204156 0.89 ENST00000398667.4
 TP53TG3C
 TP53 target 3C
chr5_-_133510456 0.89 ENST00000520417.1
 SKP1
 S-phase kinase-associated protein 1
chr13_-_38172863 0.85 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
 POSTN
 periostin, osteoblast specific factor
chrX_+_30261847 0.83 ENST00000378981.3
ENST00000397550.1
 MAGEB1
 melanoma antigen family B, 1
chr22_+_19467261 0.82 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
 CDC45
 cell division cycle 45
chr3_+_20081515 0.81 ENST00000263754.4
 KAT2B
 K(lysine) acetyltransferase 2B
chr10_-_69597810 0.81 ENST00000483798.2
 DNAJC12
 DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_-_119278446 0.79 ENST00000264246.3
 CD80
 CD80 molecule
chr3_-_119278376 0.79 ENST00000478182.1
 CD80
 CD80 molecule
chr6_+_32709119 0.78 ENST00000374940.3
 HLA-DQA2
 major histocompatibility complex, class II, DQ alpha 2
chr11_-_118213331 0.77 ENST00000392884.2
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr8_-_86253888 0.77 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
 CA1
 carbonic anhydrase I
chr14_-_21516590 0.77 ENST00000555026.1
 NDRG2
 NDRG family member 2
chr1_-_150738261 0.76 ENST00000448301.2
ENST00000368985.3
 CTSS
 cathepsin S
chrX_-_48056199 0.75 ENST00000311798.1
ENST00000347757.1
 SSX5
 synovial sarcoma, X breakpoint 5
chr22_+_19466980 0.74 ENST00000407835.1
ENST00000438587.1
 CDC45
 cell division cycle 45
chr22_-_39268308 0.73 ENST00000407418.3
 CBX6
 chromobox homolog 6
chr6_+_35996859 0.72 ENST00000472333.1
 MAPK14
 mitogen-activated protein kinase 14
chr6_+_57182400 0.71 ENST00000607273.1
 PRIM2
 primase, DNA, polypeptide 2 (58kDa)
chr3_+_178276488 0.70 ENST00000432997.1
ENST00000455865.1
 KCNMB2
 potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr10_-_75226166 0.69 ENST00000544628.1
 PPP3CB
 protein phosphatase 3, catalytic subunit, beta isozyme
chr1_+_25598989 0.69 ENST00000454452.2
 RHD
 Rh blood group, D antigen
chrX_-_48216101 0.68 ENST00000298396.2
ENST00000376893.3
 SSX3
 synovial sarcoma, X breakpoint 3
chr11_+_125496619 0.68 ENST00000532669.1
ENST00000278916.3
 CHEK1
 checkpoint kinase 1
chrX_-_23926004 0.68 ENST00000379226.4
ENST00000379220.3
 APOO
 apolipoprotein O
chr13_-_47012325 0.67 ENST00000409879.2
 KIAA0226L
 KIAA0226-like
chr10_+_91152303 0.67 ENST00000371804.3
 IFIT1
 interferon-induced protein with tetratricopeptide repeats 1
chr11_-_118213455 0.67 ENST00000300692.4
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr1_+_241695670 0.66 ENST00000366557.4
 KMO
 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_-_33041378 0.65 ENST00000428995.1
 HLA-DPA1
 major histocompatibility complex, class II, DP alpha 1
chr10_-_98031310 0.65 ENST00000427367.2
ENST00000413476.2
 BLNK
 B-cell linker
chr9_+_135854091 0.65 ENST00000450530.1
ENST00000534944.1
 GFI1B
 growth factor independent 1B transcription repressor
chr19_-_53662257 0.64 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
 ZNF347
 zinc finger protein 347
chr14_-_106725723 0.64 ENST00000390609.2
 IGHV3-23
 immunoglobulin heavy variable 3-23
chr2_+_232573208 0.62 ENST00000409115.3
 PTMA
 prothymosin, alpha
chr12_+_58176525 0.61 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
 TSFM
 Ts translation elongation factor, mitochondrial
chr6_-_39197226 0.61 ENST00000359534.3
 KCNK5
 potassium channel, subfamily K, member 5
chr5_+_141346385 0.61 ENST00000513019.1
ENST00000356143.1
 RNF14
 ring finger protein 14
chr1_+_95616933 0.60 ENST00000604203.1
 RP11-57H12.6
 TMEM56-RWDD3 readthrough
chr18_-_31628558 0.59 ENST00000535384.1
 NOL4
 nucleolar protein 4
chr10_-_98031265 0.59 ENST00000224337.5
ENST00000371176.2
 BLNK
 B-cell linker
chr11_-_62609281 0.56 ENST00000525239.1
ENST00000538098.2
 WDR74
 WD repeat domain 74
chr1_+_196621156 0.56 ENST00000359637.2
 CFH
 complement factor H
chr14_-_106733624 0.55 ENST00000390610.2
 IGHV1-24
 immunoglobulin heavy variable 1-24
chr1_-_25747283 0.54 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
 RHCE
 Rh blood group, CcEe antigens
chr12_-_21927736 0.54 ENST00000240662.2
 KCNJ8
 potassium inwardly-rectifying channel, subfamily J, member 8
chr1_+_43291220 0.54 ENST00000372514.3
 ERMAP
 erythroblast membrane-associated protein (Scianna blood group)
chr11_-_118213360 0.53 ENST00000529594.1
 CD3D
 CD3d molecule, delta (CD3-TCR complex)
chr1_-_247094628 0.53 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
 AHCTF1
 AT hook containing transcription factor 1
chr2_+_232573222 0.53 ENST00000341369.7
ENST00000409683.1
 PTMA
 prothymosin, alpha
chr6_+_26156551 0.53 ENST00000304218.3
 HIST1H1E
 histone cluster 1, H1e
chr19_+_30433110 0.51 ENST00000542441.2
ENST00000392271.1
 URI1
 URI1, prefoldin-like chaperone
chr1_+_70820451 0.50 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
 HHLA3
 HERV-H LTR-associating 3
chr12_-_9913489 0.50 ENST00000228434.3
ENST00000536709.1
 CD69
 CD69 molecule
chr7_+_77469439 0.50 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
 PHTF2
 putative homeodomain transcription factor 2
chr21_-_33975547 0.49 ENST00000431599.1
 C21orf59
 chromosome 21 open reading frame 59
chr3_+_69928256 0.48 ENST00000394355.2
 MITF
 microphthalmia-associated transcription factor
chr1_+_100316041 0.48 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
 AGL
 amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr18_+_61554932 0.48 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr4_+_80584903 0.47 ENST00000506460.1
 RP11-452C8.1
 RP11-452C8.1
chr10_-_69597915 0.47 ENST00000225171.2
 DNAJC12
 DnaJ (Hsp40) homolog, subfamily C, member 12
chr9_+_125132803 0.47 ENST00000540753.1
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_-_20193370 0.46 ENST00000558565.2
 IGHV3OR15-7
 immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr10_-_62493223 0.45 ENST00000373827.2
 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
chr14_-_106668095 0.45 ENST00000390606.2
 IGHV3-20
 immunoglobulin heavy variable 3-20
chr8_+_11666649 0.45 ENST00000528643.1
ENST00000525777.1
 FDFT1
 farnesyl-diphosphate farnesyltransferase 1
chr3_-_176914238 0.44 ENST00000430069.1
ENST00000428970.1
 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
chr22_-_29107919 0.43 ENST00000434810.1
ENST00000456369.1
 CHEK2
 checkpoint kinase 2
chr1_+_25599018 0.41 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
 RHD
 Rh blood group, D antigen
chr12_-_91546926 0.41 ENST00000550758.1
 DCN
 decorin
chr6_-_26250835 0.41 ENST00000446824.2
 HIST1H3F
 histone cluster 1, H3f
chr11_+_2415061 0.41 ENST00000481687.1
 CD81
 CD81 molecule
chr12_-_91573249 0.39 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
 DCN
 decorin
chr8_+_27950619 0.39 ENST00000542181.1
ENST00000524103.1
ENST00000537665.1
ENST00000380353.4
ENST00000520288.1
 ELP3
 elongator acetyltransferase complex subunit 3
chr4_-_38806404 0.39 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
 TLR1
 toll-like receptor 1
chr7_+_116593433 0.39 ENST00000323984.3
ENST00000393449.1
 ST7
 suppression of tumorigenicity 7
chr15_+_35270552 0.39 ENST00000391457.2
 AC114546.1
 HCG37415; PRO1914; Uncharacterized protein
chr9_-_110251836 0.39 ENST00000374672.4
 KLF4
 Kruppel-like factor 4 (gut)
chr7_+_129906660 0.38 ENST00000222481.4
 CPA2
 carboxypeptidase A2 (pancreatic)
chr2_+_185463093 0.38 ENST00000302277.6
 ZNF804A
 zinc finger protein 804A
chr6_-_136847610 0.38 ENST00000454590.1
ENST00000432797.2
 MAP7
 microtubule-associated protein 7
chr10_+_35484053 0.37 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
 CREM
 cAMP responsive element modulator
chr12_+_21525818 0.37 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
 IAPP
 islet amyloid polypeptide
chr1_+_241695424 0.36 ENST00000366558.3
ENST00000366559.4
 KMO
 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_+_166095898 0.36 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
 SCN2A
 sodium channel, voltage-gated, type II, alpha subunit
chr4_-_100356844 0.36 ENST00000437033.2
 ADH7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr6_-_136847099 0.36 ENST00000438100.2
 MAP7
 microtubule-associated protein 7
chr4_+_147096837 0.36 ENST00000296581.5
ENST00000502781.1
 LSM6
 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_106631966 0.36 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
 GSTCD
 glutathione S-transferase, C-terminal domain containing
chr20_-_16554078 0.35 ENST00000354981.2
ENST00000355755.3
ENST00000378003.2
ENST00000408042.1
 KIF16B
 kinesin family member 16B
chrX_+_77166172 0.35 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
 ATP7A
 ATPase, Cu++ transporting, alpha polypeptide
chr1_+_196621002 0.35 ENST00000367429.4
ENST00000439155.2
 CFH
 complement factor H
chr12_-_54653313 0.35 ENST00000550411.1
ENST00000439541.2
 CBX5
 chromobox homolog 5
chr8_-_101962777 0.35 ENST00000395951.3
 YWHAZ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr3_+_150321068 0.34 ENST00000471696.1
ENST00000477889.1
ENST00000485923.1
 SELT
 Selenoprotein T
chr17_-_2996290 0.33 ENST00000331459.1
 OR1D2
 olfactory receptor, family 1, subfamily D, member 2
chr3_-_119396193 0.33 ENST00000484810.1
ENST00000497116.1
ENST00000261070.2
 COX17
 COX17 cytochrome c oxidase copper chaperone
chr4_-_153274078 0.33 ENST00000263981.5
 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr5_+_140213815 0.33 ENST00000525929.1
ENST00000378125.3
 PCDHA7
 protocadherin alpha 7
chr12_-_87232644 0.32 ENST00000549405.2
 MGAT4C
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_44001172 0.32 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
 DYNC2LI1
 dynein, cytoplasmic 2, light intermediate chain 1
chr11_+_2405833 0.32 ENST00000527343.1
ENST00000464784.2
 CD81
 CD81 molecule
chr6_-_133055815 0.32 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
 VNN3
 vanin 3
chr19_-_17185848 0.32 ENST00000593360.1
 HAUS8
 HAUS augmin-like complex, subunit 8
chr2_+_234601512 0.32 ENST00000305139.6
 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_149969871 0.32 ENST00000335643.8
ENST00000444282.1
 KATNA1
 katanin p60 (ATPase containing) subunit A 1
chr3_+_39424828 0.32 ENST00000273158.4
ENST00000431510.1
 SLC25A38
 solute carrier family 25, member 38
chr9_+_125133315 0.31 ENST00000223423.4
ENST00000362012.2
 PTGS1
 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_14026063 0.31 ENST00000443608.1
ENST00000438956.1
 ETV1
 ets variant 1
chr14_+_39703112 0.31 ENST00000555143.1
ENST00000280082.3
 MIA2
 melanoma inhibitory activity 2
chr3_+_122044084 0.31 ENST00000264474.3
ENST00000479204.1
 CSTA
 cystatin A (stefin A)
chr19_-_14889349 0.31 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
 EMR2
 egf-like module containing, mucin-like, hormone receptor-like 2
chr16_+_1728257 0.30 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
 HN1L
 hematological and neurological expressed 1-like
chr15_-_22448819 0.30 ENST00000604066.1
 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr6_-_149969829 0.30 ENST00000367411.2
 KATNA1
 katanin p60 (ATPase containing) subunit A 1
chr4_+_170541835 0.30 ENST00000504131.2
 CLCN3
 chloride channel, voltage-sensitive 3
chr2_-_225811747 0.30 ENST00000409592.3
 DOCK10
 dedicator of cytokinesis 10
chr22_-_19466683 0.29 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
 UFD1L
 ubiquitin fusion degradation 1 like (yeast)
chr11_-_236326 0.29 ENST00000525237.1
ENST00000532956.1
ENST00000525319.1
ENST00000524564.1
ENST00000382743.4
 SIRT3
 sirtuin 3
chr18_+_61442629 0.29 ENST00000398019.2
ENST00000540675.1
 SERPINB7
 serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr16_+_1728305 0.29 ENST00000569765.1
 HN1L
 hematological and neurological expressed 1-like
chr7_-_14026123 0.29 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
 ETV1
 ets variant 1
chr6_+_30297306 0.29 ENST00000420746.1
ENST00000513556.1
 TRIM39
TRIM39-RPP21
 tripartite motif containing 39
TRIM39-RPP21 readthrough
chr19_-_4540486 0.28 ENST00000306390.6
 LRG1
 leucine-rich alpha-2-glycoprotein 1
chr12_-_91573316 0.28 ENST00000393155.1
 DCN
 decorin
chr18_-_57027194 0.28 ENST00000251047.5
 LMAN1
 lectin, mannose-binding, 1
chr8_+_75736761 0.28 ENST00000260113.2
 PI15
 peptidase inhibitor 15
chr2_+_166326157 0.28 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
 CSRNP3
 cysteine-serine-rich nuclear protein 3
chr11_+_71249071 0.27 ENST00000398534.3
 KRTAP5-8
 keratin associated protein 5-8
chr1_+_50571949 0.27 ENST00000357083.4
 ELAVL4
 ELAV like neuron-specific RNA binding protein 4
chr1_+_110254850 0.27 ENST00000369812.5
ENST00000256593.3
ENST00000369813.1
 GSTM5
 glutathione S-transferase mu 5
chr5_+_33440802 0.27 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
 TARS
 threonyl-tRNA synthetase
chr6_+_30312908 0.27 ENST00000433076.2
ENST00000442966.2
ENST00000428040.2
ENST00000436442.2
 RPP21
 ribonuclease P/MRP 21kDa subunit
chr1_-_9132311 0.27 ENST00000474145.1
 SLC2A5
 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr22_-_39268192 0.27 ENST00000216083.6
 CBX6
 chromobox homolog 6
chr7_+_80267973 0.26 ENST00000394788.3
ENST00000447544.2
 CD36
 CD36 molecule (thrombospondin receptor)
chr19_-_1650666 0.26 ENST00000588136.1
 TCF3
 transcription factor 3
chr12_-_21487829 0.26 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
 SLCO1A2
 solute carrier organic anion transporter family, member 1A2
chr8_+_98900132 0.26 ENST00000520016.1
 MATN2
 matrilin 2
chr14_-_23877474 0.26 ENST00000405093.3
 MYH6
 myosin, heavy chain 6, cardiac muscle, alpha
chr16_-_4401258 0.26 ENST00000577031.1
 PAM16
 presequence translocase-associated motor 16 homolog (S. cerevisiae)
chr13_+_111855414 0.25 ENST00000375737.5
 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
chrX_+_65382381 0.25 ENST00000519389.1
 HEPH
 hephaestin
chr3_-_118959733 0.25 ENST00000459778.1
ENST00000359213.3
 B4GALT4
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr1_+_174769006 0.25 ENST00000489615.1
 RABGAP1L
 RAB GTPase activating protein 1-like
chr1_-_231560790 0.25 ENST00000366641.3
 EGLN1
 egl-9 family hypoxia-inducible factor 1
chr7_+_96634850 0.25 ENST00000518156.2
 DLX6
 distal-less homeobox 6
chr4_-_76957214 0.24 ENST00000306621.3
 CXCL11
 chemokine (C-X-C motif) ligand 11
chrX_+_99839799 0.24 ENST00000373031.4
 TNMD
 tenomodulin
chr4_-_87028478 0.24 ENST00000515400.1
ENST00000395157.3
 MAPK10
 mitogen-activated protein kinase 10
chr3_-_150320937 0.24 ENST00000479209.1
 SERP1
 stress-associated endoplasmic reticulum protein 1
chr22_-_19466732 0.24 ENST00000263202.10
ENST00000360834.4
 UFD1L
 ubiquitin fusion degradation 1 like (yeast)
chr11_+_119076745 0.24 ENST00000264033.4
 CBL
 Cbl proto-oncogene, E3 ubiquitin protein ligase
chr11_-_114466477 0.24 ENST00000375478.3
 NXPE4
 neurexophilin and PC-esterase domain family, member 4
chr4_-_47465666 0.24 ENST00000381571.4
 COMMD8
 COMM domain containing 8
chr4_-_38858428 0.24 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
 TLR6
TLR1
 toll-like receptor 6
toll-like receptor 1
chr1_+_41204506 0.24 ENST00000525290.1
ENST00000530965.1
ENST00000416859.2
ENST00000308733.5
 NFYC
 nuclear transcription factor Y, gamma
chr2_-_175462456 0.23 ENST00000409891.1
ENST00000410117.1
 WIPF1
 WAS/WASL interacting protein family, member 1
chr12_-_108955070 0.23 ENST00000228284.3
ENST00000546611.1
 SART3
 squamous cell carcinoma antigen recognized by T cells 3
chr13_-_31038370 0.23 ENST00000399489.1
ENST00000339872.4
 HMGB1
 high mobility group box 1
chr12_+_50794592 0.23 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
 LARP4
 La ribonucleoprotein domain family, member 4
chr12_-_71182695 0.23 ENST00000342084.4
 PTPRR
 protein tyrosine phosphatase, receptor type, R
chr1_+_59775752 0.23 ENST00000371212.1
 FGGY
 FGGY carbohydrate kinase domain containing
chr10_-_94257512 0.23 ENST00000371581.5
 IDE
 insulin-degrading enzyme
chr2_-_233641265 0.23 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
 KCNJ13
 potassium inwardly-rectifying channel, subfamily J, member 13
chr8_+_104831554 0.23 ENST00000408894.2
 RIMS2
 regulating synaptic membrane exocytosis 2
chr12_-_22063787 0.23 ENST00000544039.1
 ABCC9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_+_152956549 0.23 ENST00000307122.2
 SPRR1A
 small proline-rich protein 1A
chr22_+_39077947 0.23 ENST00000216034.4
 TOMM22
 translocase of outer mitochondrial membrane 22 homolog (yeast)
chr12_-_371994 0.22 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
 SLC6A13
 solute carrier family 6 (neurotransmitter transporter), member 13
chr11_-_83984231 0.22 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
 DLG2
 discs, large homolog 2 (Drosophila)
chr11_+_64794875 0.22 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
 SNX15
 sorting nexin 15
chr20_+_43104508 0.22 ENST00000262605.4
ENST00000372904.3
 TTPAL
 tocopherol (alpha) transfer protein-like
chr1_-_32169920 0.22 ENST00000373672.3
ENST00000373668.3
 COL16A1
 collagen, type XVI, alpha 1
chr8_+_99956759 0.21 ENST00000522510.1
ENST00000457907.2
 OSR2
 odd-skipped related transciption factor 2
chrX_+_100646190 0.21 ENST00000471855.1
 RPL36A
 ribosomal protein L36a
chr18_-_31802282 0.21 ENST00000535475.1
 NOL4
 nucleolar protein 4
chr9_-_93405352 0.21 ENST00000375765.3
 DIRAS2
 DIRAS family, GTP-binding RAS-like 2
chr11_+_236959 0.21 ENST00000431206.2
ENST00000528906.1
 PSMD13
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr3_+_190105909 0.21 ENST00000456423.1
 CLDN16
 claudin 16
chr14_+_22520762 0.21 ENST00000390449.3
 TRAV21
 T cell receptor alpha variable 21

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.7 4.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.6 2.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.5 1.6 GO:0031938 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 0.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.2 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3 1.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) bone marrow development(GO:0048539)
0.3 0.9 GO:1990523 bone regeneration(GO:1990523)
0.3 1.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.2 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.6 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.2 0.6 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.2 1.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.2 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 2.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.1 0.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.4 GO:0071409 negative regulation of muscle hyperplasia(GO:0014740) cellular response to cycloheximide(GO:0071409)
0.1 0.5 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.3 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.4 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.1 0.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.1 0.9 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.4 GO:0060613 fat pad development(GO:0060613)
0.1 0.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.8 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 1.6 GO:0006825 copper ion transport(GO:0006825)
0.1 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.2 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 1.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0070318 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 2.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0015816 glycine transport(GO:0015816)
0.0 0.3 GO:0097319 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.2 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.5 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.3 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:2000317 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.5 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.8 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0009441 fatty acid alpha-oxidation(GO:0001561) glycolate metabolic process(GO:0009441)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.6 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 2.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.6 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.3 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.1 GO:0086073 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 1.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0007595 lactation(GO:0007595)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 1.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 0.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.2 0.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.5 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 0.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 4.0 GO:0031489 myosin V binding(GO:0031489)
0.1 0.7 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.5 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 1.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.8 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.3 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 2.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.5 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.5 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 1.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.9 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 1.7 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 3.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0052724 inositol-1,3,4,5,6-pentakisphosphate kinase activity(GO:0000827) inositol hexakisphosphate kinase activity(GO:0000828) inositol heptakisphosphate kinase activity(GO:0000829) inositol hexakisphosphate 5-kinase activity(GO:0000832) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.0 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.0 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 3.5 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.5 1.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 4.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.6 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 3.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.8 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.9 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.8 GO:0000125 PCAF complex(GO:0000125)
0.1 0.2 GO:0005916 fascia adherens(GO:0005916)
0.1 1.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.3 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 2.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.0 1.5 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 2.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.0 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.3 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)