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ENCODE cell lines, expression (Ernst 2011)

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Results for CDX2

Z-value: 0.57

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Transcription factors associated with CDX2

Gene Symbol Gene ID Gene Info
ENSG00000165556.9 CDX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CDX2hg19_v2_chr13_-_28545276_28545276-0.194.8e-01Click!

Activity profile of CDX2 motif

Sorted Z-values of CDX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_52989217 1.53 ENST00000570287.2
TCF4
transcription factor 4
chr4_+_174089904 1.48 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_158979792 1.44 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr1_+_158979686 1.37 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr18_-_53177984 0.86 ENST00000543082.1
TCF4
transcription factor 4
chr18_-_52989525 0.79 ENST00000457482.3
TCF4
transcription factor 4
chr4_-_72649763 0.77 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chrX_-_101771645 0.76 ENST00000289373.4
TMSB15A
thymosin beta 15a
chr21_-_28338732 0.74 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_+_45286706 0.72 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr3_-_112127981 0.63 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr10_-_127505167 0.61 ENST00000368786.1
UROS
uroporphyrinogen III synthase
chr6_+_12958137 0.56 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr5_+_86564739 0.52 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr4_-_15939963 0.51 ENST00000259988.2
FGFBP1
fibroblast growth factor binding protein 1
chr11_+_71900572 0.51 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr4_-_169239921 0.50 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr11_+_71900703 0.48 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chrX_-_15619076 0.45 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_+_26798955 0.45 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr2_+_219081817 0.45 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr4_-_76439483 0.44 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chrX_+_65384052 0.43 ENST00000336279.5
ENST00000458621.1
HEPH
hephaestin
chr20_-_7921090 0.41 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr10_+_13652047 0.40 ENST00000601460.1
RP11-295P9.3
Uncharacterized protein
chrX_+_65384182 0.37 ENST00000441993.2
ENST00000419594.1
HEPH
hephaestin
chr1_-_23886285 0.37 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr18_+_3252206 0.35 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr7_-_41742697 0.35 ENST00000242208.4
INHBA
inhibin, beta A
chr4_-_164534657 0.34 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr1_+_84630645 0.34 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_43919346 0.34 ENST00000372430.3
ENST00000372433.1
ENST00000372434.1
ENST00000486909.1
HYI
hydroxypyruvate isomerase (putative)
chr12_+_64173583 0.33 ENST00000261234.6
TMEM5
transmembrane protein 5
chr1_-_23495340 0.31 ENST00000418342.1
LUZP1
leucine zipper protein 1
chr1_+_109419596 0.31 ENST00000435987.1
ENST00000264126.3
GPSM2
G-protein signaling modulator 2
chr18_+_3252265 0.30 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_25205568 0.29 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr18_+_21032781 0.29 ENST00000339486.3
RIOK3
RIO kinase 3
chr21_-_27423339 0.29 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr6_+_32812568 0.28 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr15_+_67418047 0.27 ENST00000540846.2
SMAD3
SMAD family member 3
chr19_+_21106081 0.27 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
ZNF85
zinc finger protein 85
chr13_-_103719196 0.27 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr10_-_21661870 0.26 ENST00000433460.1
RP11-275N1.1
RP11-275N1.1
chr15_-_55541227 0.26 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr4_-_69536346 0.25 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr6_+_25754927 0.25 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chr3_-_196911002 0.25 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr12_-_52828147 0.23 ENST00000252245.5
KRT75
keratin 75
chr9_-_95640218 0.23 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr1_-_54355430 0.22 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr19_+_21265028 0.21 ENST00000291770.7
ZNF714
zinc finger protein 714
chr15_+_35270552 0.21 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr3_+_149191723 0.21 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr9_+_2029019 0.20 ENST00000382194.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_-_46690839 0.20 ENST00000498634.2
HOXB8
homeobox B8
chr9_-_95055956 0.20 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
IARS
isoleucyl-tRNA synthetase
chr7_+_64838712 0.19 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr21_-_27462351 0.18 ENST00000448850.1
APP
amyloid beta (A4) precursor protein
chr17_+_68071389 0.18 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_+_134464376 0.18 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr22_-_30642782 0.17 ENST00000249075.3
LIF
leukemia inhibitory factor
chr12_+_56546363 0.17 ENST00000551834.1
ENST00000552568.1
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr1_-_237167718 0.16 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr4_-_76944621 0.16 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr7_+_64838786 0.16 ENST00000450302.2
ZNF92
zinc finger protein 92
chr19_-_54619006 0.16 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr12_+_56546223 0.15 ENST00000550443.1
ENST00000207437.5
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr1_+_210001309 0.14 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr17_+_61086917 0.14 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr11_-_3400442 0.14 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr1_+_151739131 0.13 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr14_+_52456327 0.13 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr19_-_54618650 0.13 ENST00000391757.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr22_-_32651326 0.13 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr19_-_48753104 0.13 ENST00000447740.2
CARD8
caspase recruitment domain family, member 8
chr19_-_48752812 0.13 ENST00000359009.4
CARD8
caspase recruitment domain family, member 8
chr9_+_137979506 0.13 ENST00000539529.1
ENST00000392991.4
ENST00000371793.3
OLFM1
olfactomedin 1
chr2_-_224467093 0.12 ENST00000305409.2
SCG2
secretogranin II
chr6_-_27775694 0.12 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr2_+_208423840 0.12 ENST00000539789.1
CREB1
cAMP responsive element binding protein 1
chr19_-_22018966 0.12 ENST00000599906.1
ENST00000354959.4
ZNF43
zinc finger protein 43
chr12_-_10959892 0.12 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr17_-_40288449 0.12 ENST00000552162.1
ENST00000550504.1
RAB5C
RAB5C, member RAS oncogene family
chr1_+_241695670 0.12 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr5_-_138534071 0.11 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr1_+_241695424 0.11 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr6_+_134274322 0.11 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr20_+_42984330 0.11 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr6_-_127840453 0.11 ENST00000556132.1
SOGA3
SOGA family member 3
chr5_-_148033726 0.11 ENST00000354217.2
ENST00000314512.6
ENST00000362016.2
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr11_-_3400330 0.11 ENST00000427810.2
ENST00000005082.9
ENST00000534569.1
ENST00000438262.2
ENST00000528796.1
ENST00000528410.1
ENST00000529678.1
ENST00000354599.6
ENST00000526601.1
ENST00000525502.1
ENST00000533036.1
ENST00000399602.4
ZNF195
zinc finger protein 195
chr14_+_52456193 0.10 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr19_+_21579908 0.10 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr12_-_18243119 0.10 ENST00000538724.1
ENST00000229002.2
RERGL
RERG/RAS-like
chr12_-_18243075 0.10 ENST00000536890.1
RERGL
RERG/RAS-like
chr6_-_26189304 0.10 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr4_+_88754069 0.10 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr7_-_122840015 0.10 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr16_-_75498553 0.10 ENST00000569276.1
ENST00000357613.4
ENST00000561878.1
ENST00000566980.1
ENST00000567194.1
TMEM170A
RP11-77K12.1
transmembrane protein 170A
Uncharacterized protein
chr4_-_39979576 0.10 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr9_-_95056010 0.10 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr2_+_233415363 0.09 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr8_+_124084899 0.09 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31
TBC1 domain family, member 31
chr12_-_10962767 0.09 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr2_-_40657397 0.08 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_204135450 0.08 ENST00000272190.8
ENST00000367195.2
REN
renin
chr19_-_53636125 0.08 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chr2_-_169887827 0.08 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr4_+_88754113 0.08 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr4_+_187148556 0.07 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr19_+_21579958 0.07 ENST00000339914.6
ENST00000599461.1
ZNF493
zinc finger protein 493
chr18_-_5396271 0.07 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr14_+_53173890 0.07 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr4_-_123377880 0.07 ENST00000226730.4
IL2
interleukin 2
chr2_+_208423891 0.07 ENST00000448277.1
ENST00000457101.1
CREB1
cAMP responsive element binding protein 1
chr14_+_53173910 0.07 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr19_-_23869999 0.07 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr22_+_32455111 0.06 ENST00000543737.1
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chrX_+_64708615 0.06 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr6_+_27782788 0.06 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr6_-_166582107 0.06 ENST00000296946.2
ENST00000461348.2
ENST00000366871.3
T
T, brachyury homolog (mouse)
chr2_+_109204909 0.06 ENST00000393310.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_+_54619125 0.06 ENST00000445811.1
ENST00000419967.1
ENST00000445124.1
ENST00000447810.1
PRPF31
pre-mRNA processing factor 31
chr3_-_123710893 0.06 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chr16_-_20338748 0.05 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr7_-_26578407 0.05 ENST00000242109.3
KIAA0087
KIAA0087
chr16_+_25228242 0.05 ENST00000219660.5
AQP8
aquaporin 8
chr16_-_21663919 0.05 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr4_+_95972822 0.05 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_+_125687987 0.05 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B
rhophilin associated tail protein 1B
chr19_+_13885252 0.05 ENST00000221576.4
C19orf53
chromosome 19 open reading frame 53
chr20_+_2276639 0.05 ENST00000381458.5
TGM3
transglutaminase 3
chr1_+_151735431 0.05 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr4_+_71248795 0.05 ENST00000304915.3
SMR3B
submaxillary gland androgen regulated protein 3B
chr10_-_96829246 0.05 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8
cytochrome P450, family 2, subfamily C, polypeptide 8
chr5_-_148033693 0.04 ENST00000377888.3
ENST00000360693.3
HTR4
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
chr18_+_55018044 0.04 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr5_+_72143988 0.04 ENST00000506351.2
TNPO1
transportin 1
chr2_+_109204743 0.04 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_-_60674037 0.04 ENST00000541371.1
ENST00000227524.4
PRPF19
pre-mRNA processing factor 19
chr3_-_123710199 0.04 ENST00000184183.4
ROPN1
rhophilin associated tail protein 1
chr3_-_67705006 0.04 ENST00000492795.1
ENST00000493112.1
ENST00000307227.5
SUCLG2
succinate-CoA ligase, GDP-forming, beta subunit
chrX_+_140982452 0.04 ENST00000544766.1
MAGEC3
melanoma antigen family C, 3
chr3_+_15045419 0.03 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr19_+_48497901 0.03 ENST00000339841.2
ELSPBP1
epididymal sperm binding protein 1
chr4_+_70894130 0.03 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr16_+_71560023 0.03 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr8_+_143761874 0.03 ENST00000301258.4
ENST00000513264.1
PSCA
prostate stem cell antigen
chr16_-_20339123 0.03 ENST00000381360.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr7_+_134464414 0.03 ENST00000361901.2
CALD1
caldesmon 1
chr16_-_21663950 0.03 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr17_+_58018269 0.03 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr11_-_4719072 0.03 ENST00000396950.3
ENST00000532598.1
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr13_+_25338290 0.03 ENST00000255324.5
ENST00000381921.1
ENST00000255325.6
RNF17
ring finger protein 17
chr22_+_41956767 0.02 ENST00000306149.7
CSDC2
cold shock domain containing C2, RNA binding
chr5_-_39270725 0.02 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr4_-_76957214 0.02 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr2_-_209010874 0.02 ENST00000260988.4
CRYGB
crystallin, gamma B
chr8_+_128426535 0.02 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chr1_+_32379174 0.02 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr11_+_60048053 0.02 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr5_-_145562147 0.01 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr2_+_210444142 0.01 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr7_-_107204918 0.01 ENST00000297135.3
COG5
component of oligomeric golgi complex 5
chr8_-_81083731 0.01 ENST00000379096.5
TPD52
tumor protein D52
chr3_-_46068969 0.01 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr1_+_53480598 0.01 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr14_-_60097524 0.01 ENST00000342503.4
RTN1
reticulon 1
chr19_+_48497962 0.01 ENST00000596043.1
ENST00000597519.1
ELSPBP1
epididymal sperm binding protein 1
chr3_+_148545586 0.00 ENST00000282957.4
ENST00000468341.1
CPB1
carboxypeptidase B1 (tissue)
chr6_-_52859968 0.00 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4

Gene Ontology Analysis

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.2 0.6 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0039534 regulation of MDA-5 signaling pathway(GO:0039533) negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.3 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 3.3 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 1.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0001842 neural fold formation(GO:0001842)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:2000320 regulation of T cell homeostatic proliferation(GO:0046013) negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.0 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.4 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 3.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.2 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 3.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 3.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 0.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0032089 NACHT domain binding(GO:0032089)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.7 GO:0050840 extracellular matrix binding(GO:0050840)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals